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The map label for this gene is dctB [H]

Identifier: 116690892

GI number: 116690892

Start: 3171574

End: 3173583

Strand: Reverse

Name: dctB [H]

Synonym: Bcen2424_2872

Alternate gene names: 116690892

Gene position: 3173583-3171574 (Counterclockwise)

Preceding gene: 116690893

Following gene: 116690891

Centisome position: 91.09

GC content: 70.75

Gene sequence:

>2010_bases
ATGAAGGAGCAGGCGGCGGCACCGCCCGCCGGCCGTGCGGCCCGCGGCGGCCGGGGTATCGAGGCGGAGGCCTATGACAC
AATAGGCGATCCGCATCGTCAGGAAGCCTCGACCGTGACGCGCCGCCTGCTCATCCTCGTCGTGCTCGCCGCCGCGCTCG
TCGCGGCGTGCGCGCTGACGTGGACGATCACCTGGCAGCGCGGCGTCGCCGAGCTGCAGCGCAATGCCGCGGTGCGGGTC
GACCGCACCACCAGCGCGCTCAAGAGCACGCTTGACCGCTACGAATCGCTGCCTTATCTGCTCGGCAGCCATCCGTACGT
GCAGGATCTGCTCGCCGACCCGAAGCGCGGCGACTACACCGCCCGCGTCAACCGCTATCTCGAAGACCTCAACGAACACG
CGCACGCGACCGTCACCTACGTGATCGGCGCGGACGGCCTGTGCGTCGCCGCCAGCAACTGGCGCGCGCCCGACAGCTTC
GTCGGGATCGAATACCGTTTCCGCCCGTATTTCCTCGATGCGATGAACGGCCAGGTCGGCCGCTTCTTCGGGATCGGCAC
GATCTCGCGCGATCCCGGTTACTACATCTCGCAGCCCGTGTGGCGCGACGGCAAGATCGCGGGCGTCGTCGTCGTGAAGC
TCAATCTCGAATGGTTCCAGGGCGCCGACGCGTCCGAGCCGCTCGTCGTCGTGGACGATCACGGGGTCGTGTTCCTGTCG
TCGGTGCCCGCGTGGAAGTACCACACGCTGCGCCCGCTCACGGGGCCGGTCGCCGCGTCGATCTACGAAACGCGCCAGTA
CGCGCAGCAACCGGTCACGCCGCTGCCGCTGCGCGTCGAGCAGACGCTCGGCGCCGACGCGGAAATCGTGCGCCTCGGCG
CCGGCCGGCGCGCGCCGCGCTTCCTCGCCAGCAAGCGCCGGATCGGCGAGCCCGACTGGCTGCTCGTCACGCTCGCGCCG
ATCGCGCCGATCGATGCCGATGCGCGCAATGCGACGATCGTCACCGGTTTCGGCTTCGTGTCGGTCGCGCTCCTGGCGTT
CTACTGGCGGATGCGCCGCGCCCGCGTGCGCGAGATGATCCGCGGCCGCGCGCTGCTGCAGCAGGCGTACGCGGAGCTGA
ACCGGCGCGTCGAGGAGCGTACGGCCGATTTGTCCGAAGCGAACGAGCAGTTGCAGAAGGAGGTCGGCGACCGGATCCGC
GCGGAGCAGGAGCTGCGCGCCGCGCACGACGAACTGATCCAGGCGAGCAAGCTCGCCGCGCTCGGCCAGATGGCGGCCGG
CATCACGCATGAACTGAACCAGCCGCTCGCGGCGCTGCGCAGCTTCTCGGACAACACGCGCGTGCTGCTCGATCGCGGCG
AGCAGGCCGCCGCGCGCGAGAATCTCGAGGCGATCGCCGCGCTCACCGAGCGGATGGGCAAGATCACCAACCAGCTGAAG
CTGTTCGTCGGCCGAGCGAAGCCGCGCAACGAGCGGGCACTCGTCGTGCGCGCGCTGCGCAGCGTGCTGTCGCTGCTCGG
CGAGCGCCTGCGCGGCGTCGCGCTCACGCTGACGCTGCAGGACGCGACCGTGTCGCCCGCGCACGACGCGCCGCTCGACC
TGGCGCGCGACTATCCCGAACTCGTCGCGCGCTGCGAGGATCTGCGCCTCGAACAGGTGCTGATCAACCTGCTCGGCAAC
GCGCTCGACGCGGTGGCCGGCGTCGCGGCGCCGGCCATCGAGGTGACGATCGCGGTGTCGGCCGCGACGCTCGCGGTCGA
GGTGCGCGACAACGGCTCCGGCATTGCGCCCGATCTGCTGCCGCGCCTGTTCGAGCCGTTCTTCACGACCAAGGAAATGG
GGCGCGGGCTCGGGCTCGGCCTCGCGATCTCGTCGTCGATCGCGAGCGACGCGGGTGGCGCGCTGACGGCACGCAACGCA
CCGTCGGGCGGCGCGCTGTTCGTCTTGACGCTGCGGCGCGCCCGCACGCATCATCCGGACTCCGTGTCCGAGCCGGCGGG
CTCGCATTAG

Upstream 100 bases:

>100_bases
TCGGCCTGGGAGAAGGAGCTCGACCGCAACAAGCTGCGCCAGGCGCTGAAGGGCGGCGGCGAAGTCGCGCCGACCGAGAC
GACGGCCGGCGTCTGACGTC

Downstream 100 bases:

>100_bases
CGTGAACAGGCCGGTCGACGAACGACCGGGATCAACGAGAGCCGCACGCACCAGCGCCGCGCGGCCTGTCAGGAGCAAGT
GACCAAGATGGCCAACCGGC

Product: periplasmic sensor signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 669; Mature: 669

Protein sequence:

>669_residues
MKEQAAAPPAGRAARGGRGIEAEAYDTIGDPHRQEASTVTRRLLILVVLAAALVAACALTWTITWQRGVAELQRNAAVRV
DRTTSALKSTLDRYESLPYLLGSHPYVQDLLADPKRGDYTARVNRYLEDLNEHAHATVTYVIGADGLCVAASNWRAPDSF
VGIEYRFRPYFLDAMNGQVGRFFGIGTISRDPGYYISQPVWRDGKIAGVVVVKLNLEWFQGADASEPLVVVDDHGVVFLS
SVPAWKYHTLRPLTGPVAASIYETRQYAQQPVTPLPLRVEQTLGADAEIVRLGAGRRAPRFLASKRRIGEPDWLLVTLAP
IAPIDADARNATIVTGFGFVSVALLAFYWRMRRARVREMIRGRALLQQAYAELNRRVEERTADLSEANEQLQKEVGDRIR
AEQELRAAHDELIQASKLAALGQMAAGITHELNQPLAALRSFSDNTRVLLDRGEQAAARENLEAIAALTERMGKITNQLK
LFVGRAKPRNERALVVRALRSVLSLLGERLRGVALTLTLQDATVSPAHDAPLDLARDYPELVARCEDLRLEQVLINLLGN
ALDAVAGVAAPAIEVTIAVSAATLAVEVRDNGSGIAPDLLPRLFEPFFTTKEMGRGLGLGLAISSSIASDAGGALTARNA
PSGGALFVLTLRRARTHHPDSVSEPAGSH

Sequences:

>Translated_669_residues
MKEQAAAPPAGRAARGGRGIEAEAYDTIGDPHRQEASTVTRRLLILVVLAAALVAACALTWTITWQRGVAELQRNAAVRV
DRTTSALKSTLDRYESLPYLLGSHPYVQDLLADPKRGDYTARVNRYLEDLNEHAHATVTYVIGADGLCVAASNWRAPDSF
VGIEYRFRPYFLDAMNGQVGRFFGIGTISRDPGYYISQPVWRDGKIAGVVVVKLNLEWFQGADASEPLVVVDDHGVVFLS
SVPAWKYHTLRPLTGPVAASIYETRQYAQQPVTPLPLRVEQTLGADAEIVRLGAGRRAPRFLASKRRIGEPDWLLVTLAP
IAPIDADARNATIVTGFGFVSVALLAFYWRMRRARVREMIRGRALLQQAYAELNRRVEERTADLSEANEQLQKEVGDRIR
AEQELRAAHDELIQASKLAALGQMAAGITHELNQPLAALRSFSDNTRVLLDRGEQAAARENLEAIAALTERMGKITNQLK
LFVGRAKPRNERALVVRALRSVLSLLGERLRGVALTLTLQDATVSPAHDAPLDLARDYPELVARCEDLRLEQVLINLLGN
ALDAVAGVAAPAIEVTIAVSAATLAVEVRDNGSGIAPDLLPRLFEPFFTTKEMGRGLGLGLAISSSIASDAGGALTARNA
PSGGALFVLTLRRARTHHPDSVSEPAGSH
>Mature_669_residues
MKEQAAAPPAGRAARGGRGIEAEAYDTIGDPHRQEASTVTRRLLILVVLAAALVAACALTWTITWQRGVAELQRNAAVRV
DRTTSALKSTLDRYESLPYLLGSHPYVQDLLADPKRGDYTARVNRYLEDLNEHAHATVTYVIGADGLCVAASNWRAPDSF
VGIEYRFRPYFLDAMNGQVGRFFGIGTISRDPGYYISQPVWRDGKIAGVVVVKLNLEWFQGADASEPLVVVDDHGVVFLS
SVPAWKYHTLRPLTGPVAASIYETRQYAQQPVTPLPLRVEQTLGADAEIVRLGAGRRAPRFLASKRRIGEPDWLLVTLAP
IAPIDADARNATIVTGFGFVSVALLAFYWRMRRARVREMIRGRALLQQAYAELNRRVEERTADLSEANEQLQKEVGDRIR
AEQELRAAHDELIQASKLAALGQMAAGITHELNQPLAALRSFSDNTRVLLDRGEQAAARENLEAIAALTERMGKITNQLK
LFVGRAKPRNERALVVRALRSVLSLLGERLRGVALTLTLQDATVSPAHDAPLDLARDYPELVARCEDLRLEQVLINLLGN
ALDAVAGVAAPAIEVTIAVSAATLAVEVRDNGSGIAPDLLPRLFEPFFTTKEMGRGLGLGLAISSSIASDAGGALTARNA
PSGGALFVLTLRRARTHHPDSVSEPAGSH

Specific function: Member of the two-component regulatory system dctB/dctD involved in the transport of C4-dicarboxylates. DctB functions as a membrane-associated protein kinase that phosphorylates dctD in response to environmental signals [H]

COG id: COG4191

COG function: function code T; Signal transduction histidine kinase regulating C4-dicarboxylate transport system

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1788549, Length=284, Percent_Identity=30.2816901408451, Blast_Score=95, Evalue=1e-20,
Organism=Escherichia coli, GI1790436, Length=258, Percent_Identity=31.3953488372093, Blast_Score=89, Evalue=8e-19,
Organism=Escherichia coli, GI1787894, Length=325, Percent_Identity=28, Blast_Score=74, Evalue=4e-14,
Organism=Escherichia coli, GI87081816, Length=295, Percent_Identity=29.8305084745763, Blast_Score=71, Evalue=3e-13,
Organism=Escherichia coli, GI1786912, Length=294, Percent_Identity=28.2312925170068, Blast_Score=68, Evalue=2e-12,
Organism=Escherichia coli, GI1789149, Length=289, Percent_Identity=25.6055363321799, Blast_Score=66, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR017055
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 72779; Mature: 72779

Theoretical pI: Translated: 8.68; Mature: 8.68

Prosite motif: PS50109 HIS_KIN ; PS00210 HEMOCYANIN_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKEQAAAPPAGRAARGGRGIEAEAYDTIGDPHRQEASTVTRRLLILVVLAAALVAACALT
CCCCCCCCCCCCCCCCCCCCCCCCHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
WTITWQRGVAELQRNAAVRVDRTTSALKSTLDRYESLPYLLGSHPYVQDLLADPKRGDYT
EEEEHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHCCCHHHCCCCHHHHHHCCCCCCCHH
ARVNRYLEDLNEHAHATVTYVIGADGLCVAASNWRAPDSFVGIEYRFRPYFLDAMNGQVG
HHHHHHHHHHHCCCCEEEEEEEECCCEEEEECCCCCCCCEEEEEEEECCEEEECCCCCCC
RFFGIGTISRDPGYYISQPVWRDGKIAGVVVVKLNLEWFQGADASEPLVVVDDHGVVFLS
EEEEECCCCCCCCCCCCCCCCCCCCEEEEEEEEEEEHHHCCCCCCCCEEEECCCCEEEEE
SVPAWKYHTLRPLTGPVAASIYETRQYAQQPVTPLPLRVEQTLGADAEIVRLGAGRRAPR
CCCCCCEEECCCCCCHHHHHHHHHHHHHHCCCCCCCCEEHHHCCCCCEEEEECCCCCCHH
FLASKRRIGEPDWLLVTLAPIAPIDADARNATIVTGFGFVSVALLAFYWRMRRARVREMI
HHHHHHCCCCCCEEEEEECCCCCCCCCCCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHH
RGRALLQQAYAELNRRVEERTADLSEANEQLQKEVGDRIRAEQELRAAHDELIQASKLAA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LGQMAAGITHELNQPLAALRSFSDNTRVLLDRGEQAAARENLEAIAALTERMGKITNQLK
HHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHH
LFVGRAKPRNERALVVRALRSVLSLLGERLRGVALTLTLQDATVSPAHDAPLDLARDYPE
HHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCEEEEEEEECCCCCCCCCCCHHHHCCHHH
LVARCEDLRLEQVLINLLGNALDAVAGVAAPAIEVTIAVSAATLAVEVRDNGSGIAPDLL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEEEEEEEEEECCCCCCCHHHH
PRLFEPFFTTKEMGRGLGLGLAISSSIASDAGGALTARNAPSGGALFVLTLRRARTHHPD
HHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCEEECCCCCCCEEEEEEEHHHHCCCCC
SVSEPAGSH
CCCCCCCCC
>Mature Secondary Structure
MKEQAAAPPAGRAARGGRGIEAEAYDTIGDPHRQEASTVTRRLLILVVLAAALVAACALT
CCCCCCCCCCCCCCCCCCCCCCCCHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
WTITWQRGVAELQRNAAVRVDRTTSALKSTLDRYESLPYLLGSHPYVQDLLADPKRGDYT
EEEEHHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHCCCHHHCCCCHHHHHHCCCCCCCHH
ARVNRYLEDLNEHAHATVTYVIGADGLCVAASNWRAPDSFVGIEYRFRPYFLDAMNGQVG
HHHHHHHHHHHCCCCEEEEEEEECCCEEEEECCCCCCCCEEEEEEEECCEEEECCCCCCC
RFFGIGTISRDPGYYISQPVWRDGKIAGVVVVKLNLEWFQGADASEPLVVVDDHGVVFLS
EEEEECCCCCCCCCCCCCCCCCCCCEEEEEEEEEEEHHHCCCCCCCCEEEECCCCEEEEE
SVPAWKYHTLRPLTGPVAASIYETRQYAQQPVTPLPLRVEQTLGADAEIVRLGAGRRAPR
CCCCCCEEECCCCCCHHHHHHHHHHHHHHCCCCCCCCEEHHHCCCCCEEEEECCCCCCHH
FLASKRRIGEPDWLLVTLAPIAPIDADARNATIVTGFGFVSVALLAFYWRMRRARVREMI
HHHHHHCCCCCCEEEEEECCCCCCCCCCCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHH
RGRALLQQAYAELNRRVEERTADLSEANEQLQKEVGDRIRAEQELRAAHDELIQASKLAA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LGQMAAGITHELNQPLAALRSFSDNTRVLLDRGEQAAARENLEAIAALTERMGKITNQLK
HHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHH
LFVGRAKPRNERALVVRALRSVLSLLGERLRGVALTLTLQDATVSPAHDAPLDLARDYPE
HHHCCCCCCCHHHHHHHHHHHHHHHHHHHHCCEEEEEEEECCCCCCCCCCCHHHHCCHHH
LVARCEDLRLEQVLINLLGNALDAVAGVAAPAIEVTIAVSAATLAVEVRDNGSGIAPDLL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEEEEEEEEEECCCCCCCHHHH
PRLFEPFFTTKEMGRGLGLGLAISSSIASDAGGALTARNAPSGGALFVLTLRRARTHHPD
HHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCEEECCCCCCCEEEEEEEHHHHCCCCC
SVSEPAGSH
CCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 3671068 [H]