| Definition | Burkholderia cenocepacia HI2424 chromosome 1, complete sequence. |
|---|---|
| Accession | NC_008542 |
| Length | 3,483,902 |
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The map label for this gene is fabG [H]
Identifier: 116690778
GI number: 116690778
Start: 3053971
End: 3054687
Strand: Reverse
Name: fabG [H]
Synonym: Bcen2424_2758
Alternate gene names: 116690778
Gene position: 3054687-3053971 (Counterclockwise)
Preceding gene: 116690779
Following gene: 116690777
Centisome position: 87.68
GC content: 70.43
Gene sequence:
>717_bases ATGCGGGCGCTCGTGACGGGCGGCAGCGGCGCACTCGGGCAGGCGATTTGCACGGCGCTCGCGCAGGCCGGCCATGAAGT GTGGGTGCATGCGAACCGCCATCTCGAGCAGGCGCAGGCCGTCGCGCAACGGATCGTCGCGGCCGGCGGCGCCGCGCACG CGATCGCGTTCGACGTGACCGACGCCGATGCGACGCTCGCCGCGCTGAAGCCGTTCATCGACGAGACGCCGGTGCAGATC CTCGTCAACAACGCGGGCATTCACGACGACGCGCCGATGGCCGGCATGTCGCGCCAGCAATGGCACAGCGTGATCGACGT GACGCTCAACGGCTTTTTCAACGTCACGCAGCCGCTGCTGCTGCCGATGATCCGCACGCGGCGCGGGCGGATCGTCAACA TCGCGTCGGTGGCCGGCGTGACCGGCAATCGCGGGCAGGCCAATTACGCGGCCGCGAAGGCGGGGCTGATCGGCGCGACG AAGTCGCTGTCGCTGGAGCTCGCGTCGCGCGGCATCACCGTGAACGCGGTGGCGCCCGGCATCATCGCGTCGCCGATGGC CGACCAGGCGTTTCCCGCGGAACGCATCAAGCAGCTCGTGCCCGCGCAGCGCGCGGGCCGGCCCGACGAAGTCGCGGCGA TGGTCGCGTATCTGGTATCCGACGCCGCGGCCTATGTGACGGGGCAGGTGTTGTCCGTCAACGGCGGGCTCGCATGA
Upstream 100 bases:
>100_bases TGCCTACGTCGCCGCGCATCGCACGAAGTGACGGCGGCGCTCGGCGGACGATGCGCGGCGGCAGCGATCGAGGGGAACAC GCGATGAACGGAGCAAGGCG
Downstream 100 bases:
>100_bases CGAAGCGCGCCGCATTCGCCTGACGTAACGCAACGCGGCGCAGGGCCGCGTGGTCGCGCGGCCTGCGCCGCATAGTGAGG AAATCGAAGTGTCCGTGCAT
Product: short chain dehydrogenase
Products: NA
Alternate protein names: 3-ketoacyl-acyl carrier protein reductase [H]
Number of amino acids: Translated: 238; Mature: 238
Protein sequence:
>238_residues MRALVTGGSGALGQAICTALAQAGHEVWVHANRHLEQAQAVAQRIVAAGGAAHAIAFDVTDADATLAALKPFIDETPVQI LVNNAGIHDDAPMAGMSRQQWHSVIDVTLNGFFNVTQPLLLPMIRTRRGRIVNIASVAGVTGNRGQANYAAAKAGLIGAT KSLSLELASRGITVNAVAPGIIASPMADQAFPAERIKQLVPAQRAGRPDEVAAMVAYLVSDAAAYVTGQVLSVNGGLA
Sequences:
>Translated_238_residues MRALVTGGSGALGQAICTALAQAGHEVWVHANRHLEQAQAVAQRIVAAGGAAHAIAFDVTDADATLAALKPFIDETPVQI LVNNAGIHDDAPMAGMSRQQWHSVIDVTLNGFFNVTQPLLLPMIRTRRGRIVNIASVAGVTGNRGQANYAAAKAGLIGAT KSLSLELASRGITVNAVAPGIIASPMADQAFPAERIKQLVPAQRAGRPDEVAAMVAYLVSDAAAYVTGQVLSVNGGLA >Mature_238_residues MRALVTGGSGALGQAICTALAQAGHEVWVHANRHLEQAQAVAQRIVAAGGAAHAIAFDVTDADATLAALKPFIDETPVQI LVNNAGIHDDAPMAGMSRQQWHSVIDVTLNGFFNVTQPLLLPMIRTRRGRIVNIASVAGVTGNRGQANYAAAKAGLIGAT KSLSLELASRGITVNAVAPGIIASPMADQAFPAERIKQLVPAQRAGRPDEVAAMVAYLVSDAAAYVTGQVLSVNGGLA
Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]
COG id: COG1028
COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]
Homologues:
Organism=Homo sapiens, GI15277342, Length=250, Percent_Identity=37.2, Blast_Score=130, Evalue=8e-31, Organism=Homo sapiens, GI40254992, Length=236, Percent_Identity=35.1694915254237, Blast_Score=119, Evalue=4e-27, Organism=Homo sapiens, GI19923817, Length=246, Percent_Identity=33.3333333333333, Blast_Score=117, Evalue=1e-26, Organism=Homo sapiens, GI32483357, Length=247, Percent_Identity=30.7692307692308, Blast_Score=100, Evalue=1e-21, Organism=Homo sapiens, GI4504505, Length=243, Percent_Identity=32.0987654320988, Blast_Score=94, Evalue=9e-20, Organism=Homo sapiens, GI10190704, Length=241, Percent_Identity=31.5352697095436, Blast_Score=91, Evalue=7e-19, Organism=Homo sapiens, GI4503301, Length=218, Percent_Identity=30.2752293577982, Blast_Score=87, Evalue=2e-17, Organism=Homo sapiens, GI5031737, Length=247, Percent_Identity=29.1497975708502, Blast_Score=84, Evalue=1e-16, Organism=Homo sapiens, GI66933014, Length=168, Percent_Identity=28.5714285714286, Blast_Score=83, Evalue=2e-16, Organism=Homo sapiens, GI126723750, Length=243, Percent_Identity=27.5720164609054, Blast_Score=79, Evalue=3e-15, Organism=Homo sapiens, GI59889578, Length=197, Percent_Identity=31.9796954314721, Blast_Score=79, Evalue=4e-15, Organism=Homo sapiens, GI4758504, Length=264, Percent_Identity=29.9242424242424, Blast_Score=77, Evalue=2e-14, Organism=Homo sapiens, GI7705925, Length=241, Percent_Identity=26.9709543568465, Blast_Score=73, Evalue=2e-13, Organism=Homo sapiens, GI7706318, Length=205, Percent_Identity=26.8292682926829, Blast_Score=72, Evalue=4e-13, Organism=Homo sapiens, GI150247226, Length=141, Percent_Identity=32.6241134751773, Blast_Score=69, Evalue=3e-12, Organism=Homo sapiens, GI33667109, Length=196, Percent_Identity=29.0816326530612, Blast_Score=65, Evalue=6e-11, Organism=Escherichia coli, GI1787335, Length=238, Percent_Identity=44.5378151260504, Blast_Score=171, Evalue=4e-44, Organism=Escherichia coli, GI2367175, Length=244, Percent_Identity=36.8852459016393, Blast_Score=130, Evalue=7e-32, Organism=Escherichia coli, GI1788459, Length=239, Percent_Identity=33.8912133891213, Blast_Score=120, Evalue=8e-29, Organism=Escherichia coli, GI87082100, Length=247, Percent_Identity=33.1983805668016, Blast_Score=120, Evalue=1e-28, Organism=Escherichia coli, GI1790717, Length=240, Percent_Identity=31.6666666666667, Blast_Score=115, Evalue=3e-27, Organism=Escherichia coli, GI1789057, Length=253, Percent_Identity=33.596837944664, Blast_Score=105, Evalue=4e-24, Organism=Escherichia coli, GI87082160, Length=249, Percent_Identity=31.7269076305221, Blast_Score=103, Evalue=7e-24, Organism=Escherichia coli, GI1789208, Length=245, Percent_Identity=31.4285714285714, Blast_Score=101, Evalue=3e-23, Organism=Escherichia coli, GI1786812, Length=245, Percent_Identity=29.7959183673469, Blast_Score=87, Evalue=8e-19, Organism=Escherichia coli, GI1787905, Length=243, Percent_Identity=31.2757201646091, Blast_Score=87, Evalue=1e-18, Organism=Escherichia coli, GI1789378, Length=251, Percent_Identity=28.2868525896414, Blast_Score=76, Evalue=2e-15, Organism=Escherichia coli, GI2367365, Length=247, Percent_Identity=30.7692307692308, Blast_Score=75, Evalue=5e-15, Organism=Escherichia coli, GI1787820, Length=242, Percent_Identity=26.8595041322314, Blast_Score=65, Evalue=4e-12, Organism=Escherichia coli, GI1787526, Length=238, Percent_Identity=26.4705882352941, Blast_Score=63, Evalue=1e-11, Organism=Caenorhabditis elegans, GI17555706, Length=241, Percent_Identity=41.49377593361, Blast_Score=156, Evalue=1e-38, Organism=Caenorhabditis elegans, GI25147288, Length=243, Percent_Identity=39.917695473251, Blast_Score=149, Evalue=9e-37, Organism=Caenorhabditis elegans, GI17560676, Length=245, Percent_Identity=33.469387755102, Blast_Score=115, Evalue=2e-26, Organism=Caenorhabditis elegans, GI17568967, Length=229, Percent_Identity=35.3711790393013, Blast_Score=102, Evalue=2e-22, Organism=Caenorhabditis elegans, GI17536025, Length=246, Percent_Identity=31.7073170731707, Blast_Score=100, Evalue=8e-22, Organism=Caenorhabditis elegans, GI17536651, Length=250, Percent_Identity=32, Blast_Score=99, Evalue=1e-21, Organism=Caenorhabditis elegans, GI115534694, Length=248, Percent_Identity=32.258064516129, Blast_Score=99, Evalue=3e-21, Organism=Caenorhabditis elegans, GI71994600, Length=255, Percent_Identity=27.843137254902, Blast_Score=90, Evalue=8e-19, Organism=Caenorhabditis elegans, GI17559104, Length=257, Percent_Identity=29.1828793774319, Blast_Score=90, Evalue=9e-19, Organism=Caenorhabditis elegans, GI71994604, Length=247, Percent_Identity=27.9352226720648, Blast_Score=89, Evalue=3e-18, Organism=Caenorhabditis elegans, GI17562910, Length=258, Percent_Identity=27.5193798449612, Blast_Score=88, Evalue=3e-18, Organism=Caenorhabditis elegans, GI17560150, Length=256, Percent_Identity=28.125, Blast_Score=88, Evalue=3e-18, Organism=Caenorhabditis elegans, GI17538480, Length=257, Percent_Identity=29.5719844357977, Blast_Score=86, Evalue=2e-17, Organism=Caenorhabditis elegans, GI17538182, Length=252, Percent_Identity=28.968253968254, Blast_Score=85, Evalue=3e-17, Organism=Caenorhabditis elegans, GI17561402, Length=255, Percent_Identity=31.7647058823529, Blast_Score=85, Evalue=3e-17, Organism=Caenorhabditis elegans, GI17561272, Length=235, Percent_Identity=30.2127659574468, Blast_Score=84, Evalue=8e-17, Organism=Caenorhabditis elegans, GI17562904, Length=262, Percent_Identity=29.3893129770992, Blast_Score=83, Evalue=1e-16, Organism=Caenorhabditis elegans, GI17560332, Length=256, Percent_Identity=27.34375, Blast_Score=82, Evalue=3e-16, Organism=Caenorhabditis elegans, GI17562906, Length=256, Percent_Identity=26.953125, Blast_Score=81, Evalue=6e-16, Organism=Caenorhabditis elegans, GI17538486, Length=256, Percent_Identity=28.125, Blast_Score=80, Evalue=1e-15, Organism=Caenorhabditis elegans, GI17562990, Length=252, Percent_Identity=25.7936507936508, Blast_Score=79, Evalue=2e-15, Organism=Caenorhabditis elegans, GI193204405, Length=260, Percent_Identity=29.6153846153846, Blast_Score=78, Evalue=3e-15, Organism=Caenorhabditis elegans, GI17563726, Length=255, Percent_Identity=27.843137254902, Blast_Score=77, Evalue=6e-15, Organism=Caenorhabditis elegans, GI72000259, Length=251, Percent_Identity=24.3027888446215, Blast_Score=76, Evalue=1e-14, Organism=Caenorhabditis elegans, GI17551412, Length=263, Percent_Identity=28.1368821292776, Blast_Score=75, Evalue=3e-14, Organism=Caenorhabditis elegans, GI17562908, Length=259, Percent_Identity=27.7992277992278, Blast_Score=75, Evalue=3e-14, Organism=Caenorhabditis elegans, GI17565030, Length=259, Percent_Identity=28.5714285714286, Blast_Score=74, Evalue=9e-14, Organism=Caenorhabditis elegans, GI17564282, Length=192, Percent_Identity=27.6041666666667, Blast_Score=73, Evalue=2e-13, Organism=Caenorhabditis elegans, GI17508895, Length=204, Percent_Identity=26.9607843137255, Blast_Score=71, Evalue=6e-13, Organism=Caenorhabditis elegans, GI17531453, Length=258, Percent_Identity=27.1317829457364, Blast_Score=69, Evalue=2e-12, Organism=Caenorhabditis elegans, GI17508651, Length=251, Percent_Identity=27.4900398406374, Blast_Score=69, Evalue=3e-12, Organism=Caenorhabditis elegans, GI17560220, Length=256, Percent_Identity=25.390625, Blast_Score=65, Evalue=3e-11, Organism=Saccharomyces cerevisiae, GI6322861, Length=245, Percent_Identity=33.0612244897959, Blast_Score=110, Evalue=1e-25, Organism=Saccharomyces cerevisiae, GI6324126, Length=243, Percent_Identity=29.2181069958848, Blast_Score=85, Evalue=9e-18, Organism=Saccharomyces cerevisiae, GI6323882, Length=230, Percent_Identity=27.8260869565217, Blast_Score=71, Evalue=1e-13, Organism=Drosophila melanogaster, GI24639444, Length=245, Percent_Identity=38.3673469387755, Blast_Score=133, Evalue=1e-31, Organism=Drosophila melanogaster, GI21357041, Length=243, Percent_Identity=32.0987654320988, Blast_Score=106, Evalue=1e-23, Organism=Drosophila melanogaster, GI28571526, Length=243, Percent_Identity=32.0987654320988, Blast_Score=101, Evalue=3e-22, Organism=Drosophila melanogaster, GI18859837, Length=230, Percent_Identity=35.2173913043478, Blast_Score=100, Evalue=8e-22, Organism=Drosophila melanogaster, GI23397609, Length=243, Percent_Identity=30.8641975308642, Blast_Score=96, Evalue=2e-20, Organism=Drosophila melanogaster, GI24644339, Length=243, Percent_Identity=30.4526748971193, Blast_Score=96, Evalue=2e-20, Organism=Drosophila melanogaster, GI24643142, Length=242, Percent_Identity=33.0578512396694, Blast_Score=95, Evalue=5e-20, Organism=Drosophila melanogaster, GI21355319, Length=249, Percent_Identity=27.3092369477912, Blast_Score=87, Evalue=1e-17, Organism=Drosophila melanogaster, GI17737361, Length=253, Percent_Identity=30.4347826086957, Blast_Score=82, Evalue=3e-16, Organism=Drosophila melanogaster, GI24644337, Length=215, Percent_Identity=30.2325581395349, Blast_Score=78, Evalue=5e-15, Organism=Drosophila melanogaster, GI24640442, Length=191, Percent_Identity=28.7958115183246, Blast_Score=70, Evalue=1e-12, Organism=Drosophila melanogaster, GI24581726, Length=173, Percent_Identity=27.1676300578035, Blast_Score=64, Evalue=7e-11, Organism=Drosophila melanogaster, GI161076933, Length=238, Percent_Identity=26.4705882352941, Blast_Score=64, Evalue=8e-11, Organism=Drosophila melanogaster, GI24584748, Length=238, Percent_Identity=26.4705882352941, Blast_Score=64, Evalue=9e-11,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR002198 - InterPro: IPR011285 - InterPro: IPR002347 - InterPro: IPR016040 [H]
Pfam domain/function: PF00106 adh_short [H]
EC number: =1.1.1.100 [H]
Molecular weight: Translated: 24511; Mature: 24511
Theoretical pI: Translated: 8.52; Mature: 8.52
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.4 %Cys (Translated Protein) 2.5 %Met (Translated Protein) 2.9 %Cys+Met (Translated Protein) 0.4 %Cys (Mature Protein) 2.5 %Met (Mature Protein) 2.9 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MRALVTGGSGALGQAICTALAQAGHEVWVHANRHLEQAQAVAQRIVAAGGAAHAIAFDVT CCEEEECCCCHHHHHHHHHHHHCCCEEEEECHHHHHHHHHHHHHHHHCCCCCEEEEEECC DADATLAALKPFIDETPVQILVNNAGIHDDAPMAGMSRQQWHSVIDVTLNGFFNVTQPLL CCHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHH LPMIRTRRGRIVNIASVAGVTGNRGQANYAAAKAGLIGATKSLSLELASRGITVNAVAPG HHHHHHCCCCEEEEHHHCCCCCCCCCCHHHHHHHCCCCCCHHHHHHHHHCCEEEEECCCC IIASPMADQAFPAERIKQLVPAQRAGRPDEVAAMVAYLVSDAAAYVTGQVLSVNGGLA HHHCCCCCCCCCHHHHHHHCCHHHCCCHHHHHHHHHHHHHHHHHHHCCEEEEECCCCC >Mature Secondary Structure MRALVTGGSGALGQAICTALAQAGHEVWVHANRHLEQAQAVAQRIVAAGGAAHAIAFDVT CCEEEECCCCHHHHHHHHHHHHCCCEEEEECHHHHHHHHHHHHHHHHCCCCCEEEEEECC DADATLAALKPFIDETPVQILVNNAGIHDDAPMAGMSRQQWHSVIDVTLNGFFNVTQPLL CCHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHH LPMIRTRRGRIVNIASVAGVTGNRGQANYAAAKAGLIGATKSLSLELASRGITVNAVAPG HHHHHHCCCCEEEEHHHCCCCCCCCCCHHHHHHHCCCCCCHHHHHHHHHCCEEEEECCCC IIASPMADQAFPAERIKQLVPAQRAGRPDEVAAMVAYLVSDAAAYVTGQVLSVNGGLA HHHCCCCCCCCCHHHHHHHCCHHHCCCHHHHHHHHHHHHHHHHHHHCCEEEEECCCCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: 9020051 [H]