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The map label for this gene is pdxA [H]

Identifier: 116690729

GI number: 116690729

Start: 2999614

End: 3000603

Strand: Reverse

Name: pdxA [H]

Synonym: Bcen2424_2709

Alternate gene names: 116690729

Gene position: 3000603-2999614 (Counterclockwise)

Preceding gene: 116690730

Following gene: 116690728

Centisome position: 86.13

GC content: 71.72

Gene sequence:

>990_bases
ATGACCACGCCCGCGCTGCAGATCGCGATCACGACCGGCGAACCCGCGGGAGTCGGCCCGGAGCTGACCGTGCAGGCGCT
GCGTGACGCCGCGCAGCGCTGGCCCGATGCGCATTTCACCGTGCTCGGCGATGCGGCGCTGCTCGACGCGCGGGCCGCGG
CGGTCGGCGCCGACCCGGCCACGCTGGCCGGCAGCGCGCAGGTGTCGGTCGCGCATCACGCGCTGGCCGTGCCCGCGCAG
GCGGGCAAGCTGGACGCGGCGAACGGCCGGTACGTGCTCGGCCTGCTCGACGCGGCGATCGACGGCGCGCTGGCGGGCCG
GTACGACGCGATCGTCACCGCACCGCTGCAGAAAAGCACGATCAACGATGCGGGCGTGCCGTTCACCGGCCATACCGAAT
ACCTGGCCGAGCGCACGCATACGCCGCGCGTCGTGATGATGCTGGCCGGCACCGGCCACCGGCCGCTGCGTGTCGCCCTC
GCGACCACGCACCTGCCGCTGAAGGACGTATCGGCCGCGCTGACGATCGACGGGCTCGTCGAGACGCTCGCGATCATCGA
TCGTGACCTGCGGCGCGACTTCGGTCTCGCCGCACCGCGCATCCTCGTGACGGGCCTGAACCCGCACGCGGGCGAGAACG
GTTATCTCGGCCGCGAGGAGATCGACGTGATCTCGCCGGCACTGGCCCGCGCGAACGCGCAACACATCGACGCGCGCGGC
CCGTATCCGGCCGACACGCTGTTCCAGCCGCGCCATCTGGCCGATGCCGATTGCGTACTCGCGATGTTCCATGACCAGGG
TCTGCCCGTGCTGAAGTACGCGACGTTCGGCGAGGGCATCAACGTGACGCTCGGGCTGCCGATCATCCGCACGTCGGTCG
ATCACGGCACCGCACTCGATCTGGCCGGCACGGGCCGCGCGGATCCGGGCAGCATGATCGCCGCGCTCGATACGGCCGTC
ACGATGGCGCGCCATCGCCGCGCAGCCTGA

Upstream 100 bases:

>100_bases
GCCGAGCAGGCGTATGCCGACTGGCTGCGCGAGCTGCGCGACTCGTCGTACGTGCAGTACAAGATCGGCGGCGTCGGCCC
GGCGAACTGAGCGAGCATCA

Downstream 100 bases:

>100_bases
CGCTGCCGGTTTACCCCATTCGTCGTATTTTTCGTTTCATTCAGTCGATGTCGAACAGCAGACAGCACCAAGGCCATTTC
GCGCGCAAGCGCTTCGGGCA

Product: 4-hydroxythreonine-4-phosphate dehydrogenase

Products: NA

Alternate protein names: 4-(phosphohydroxy)-L-threonine dehydrogenase [H]

Number of amino acids: Translated: 329; Mature: 328

Protein sequence:

>329_residues
MTTPALQIAITTGEPAGVGPELTVQALRDAAQRWPDAHFTVLGDAALLDARAAAVGADPATLAGSAQVSVAHHALAVPAQ
AGKLDAANGRYVLGLLDAAIDGALAGRYDAIVTAPLQKSTINDAGVPFTGHTEYLAERTHTPRVVMMLAGTGHRPLRVAL
ATTHLPLKDVSAALTIDGLVETLAIIDRDLRRDFGLAAPRILVTGLNPHAGENGYLGREEIDVISPALARANAQHIDARG
PYPADTLFQPRHLADADCVLAMFHDQGLPVLKYATFGEGINVTLGLPIIRTSVDHGTALDLAGTGRADPGSMIAALDTAV
TMARHRRAA

Sequences:

>Translated_329_residues
MTTPALQIAITTGEPAGVGPELTVQALRDAAQRWPDAHFTVLGDAALLDARAAAVGADPATLAGSAQVSVAHHALAVPAQ
AGKLDAANGRYVLGLLDAAIDGALAGRYDAIVTAPLQKSTINDAGVPFTGHTEYLAERTHTPRVVMMLAGTGHRPLRVAL
ATTHLPLKDVSAALTIDGLVETLAIIDRDLRRDFGLAAPRILVTGLNPHAGENGYLGREEIDVISPALARANAQHIDARG
PYPADTLFQPRHLADADCVLAMFHDQGLPVLKYATFGEGINVTLGLPIIRTSVDHGTALDLAGTGRADPGSMIAALDTAV
TMARHRRAA
>Mature_328_residues
TTPALQIAITTGEPAGVGPELTVQALRDAAQRWPDAHFTVLGDAALLDARAAAVGADPATLAGSAQVSVAHHALAVPAQA
GKLDAANGRYVLGLLDAAIDGALAGRYDAIVTAPLQKSTINDAGVPFTGHTEYLAERTHTPRVVMMLAGTGHRPLRVALA
TTHLPLKDVSAALTIDGLVETLAIIDRDLRRDFGLAAPRILVTGLNPHAGENGYLGREEIDVISPALARANAQHIDARGP
YPADTLFQPRHLADADCVLAMFHDQGLPVLKYATFGEGINVTLGLPIIRTSVDHGTALDLAGTGRADPGSMIAALDTAVT
MARHRRAA

Specific function: Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) [H]

COG id: COG1995

COG function: function code H; Pyridoxal phosphate biosynthesis protein

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the pdxA family [H]

Homologues:

Organism=Escherichia coli, GI1786237, Length=326, Percent_Identity=53.680981595092, Blast_Score=326, Evalue=1e-90,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005255 [H]

Pfam domain/function: PF04166 PdxA [H]

EC number: =1.1.1.262 [H]

Molecular weight: Translated: 34228; Mature: 34097

Theoretical pI: Translated: 6.32; Mature: 6.32

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTPALQIAITTGEPAGVGPELTVQALRDAAQRWPDAHFTVLGDAALLDARAAAVGADPA
CCCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHCCCCCH
TLAGSAQVSVAHHALAVPAQAGKLDAANGRYVLGLLDAAIDGALAGRYDAIVTAPLQKST
HCCCCCEEEEHHHEEECCCCCCCEECCCCCEEEEEHHHHHHHHHCCCCCEEEECCCCCCC
INDAGVPFTGHTEYLAERTHTPRVVMMLAGTGHRPLRVALATTHLPLKDVSAALTIDGLV
CCCCCCCCCCCHHHHHHCCCCCEEEEEEECCCCCCEEEEEEECCCCHHHHHHHEEHHHHH
ETLAIIDRDLRRDFGLAAPRILVTGLNPHAGENGYLGREEIDVISPALARANAQHIDARG
HHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCC
PYPADTLFQPRHLADADCVLAMFHDQGLPVLKYATFGEGINVTLGLPIIRTSVDHGTALD
CCCCCCCCCCCCCCCCCEEEEEECCCCCCEEEEEECCCCEEEEECCEEEEECCCCCCEEE
LAGTGRADPGSMIAALDTAVTMARHRRAA
ECCCCCCCCCHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TTPALQIAITTGEPAGVGPELTVQALRDAAQRWPDAHFTVLGDAALLDARAAAVGADPA
CCCEEEEEEECCCCCCCCHHHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHHCCCCCH
TLAGSAQVSVAHHALAVPAQAGKLDAANGRYVLGLLDAAIDGALAGRYDAIVTAPLQKST
HCCCCCEEEEHHHEEECCCCCCCEECCCCCEEEEEHHHHHHHHHCCCCCEEEECCCCCCC
INDAGVPFTGHTEYLAERTHTPRVVMMLAGTGHRPLRVALATTHLPLKDVSAALTIDGLV
CCCCCCCCCCCHHHHHHCCCCCEEEEEEECCCCCCEEEEEEECCCCHHHHHHHEEHHHHH
ETLAIIDRDLRRDFGLAAPRILVTGLNPHAGENGYLGREEIDVISPALARANAQHIDARG
HHHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCC
PYPADTLFQPRHLADADCVLAMFHDQGLPVLKYATFGEGINVTLGLPIIRTSVDHGTALD
CCCCCCCCCCCCCCCCCEEEEEECCCCCCEEEEEECCCCEEEEECCEEEEECCCCCCEEE
LAGTGRADPGSMIAALDTAVTMARHRRAA
ECCCCCCCCCHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA