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The map label for this gene is surA

Identifier: 116690730

GI number: 116690730

Start: 3000614

End: 3001972

Strand: Reverse

Name: surA

Synonym: Bcen2424_2710

Alternate gene names: 116690730

Gene position: 3001972-3000614 (Counterclockwise)

Preceding gene: 116690731

Following gene: 116690729

Centisome position: 86.17

GC content: 68.87

Gene sequence:

>1359_bases
ATGAAGAAAACCCTTCGTTTCGCGGCAGTCGTGTCCAGCCTCGCCGCGTCCGCCGCGCTGCTCGTCGCCGCGCCGGCCGC
GGCGCAGGCGCTCGGTTCGCAAGGTGCGCAGCTCGCCGACGAAGTCGTCGCGGTCGTCAACAACGACGTGATCACGGGCC
GCGAACTCGACCAGCGCGTCGGCCTGATCGCGCGCCGGCTGCAGCAGCAGAACGCGCCGGTGCCGCCGGCCGACCAGCTG
CGCGCGCAGGTGCTGAACCAGATGGTGCTCGAGCGTATCCAGGTGCAGAAGGCCAAGGACGACGGAATCCGTATCGACGA
CGCGACCGTGCAGGCCACGCTGCAGCGTCTCGCGCAGGCGAACGGGATGACGCTCGACCAGTACCGCGGGCGCCTCGAGG
CGCAAGGCGTGCCCTGGAGCATCTTCACGAACGACGCGCGCACCGAGCTGATGCTGTCGAAGCTGCGCGAGCGCGAGGTC
GACGGCAAGATCACGGTGTCGGACGCCGAGGTCGCGAACTACATCGCGAGCCAGCGCGGGCCGAACGCGTCGCAGCAGCA
GGACCTGCGCTTCCAGCACATCTTCATCAAGGCGCCCACCAACGCGCCGCAGGCCGACATCGAGGCCGCGCAGAAGAAGG
CCGACGCGCTGCTGCAGCAGGCGAAGTCGGGCGCCGATTTCGAGCGCCTCGCGAAGAACAACTCCGAAGCGAACGACGCG
AAGAAGGGCGGCGATCTCGGCTTCAAGTCGCCGAGCGCGCTGCCGGCCGACGTCGTCGACGCCGCGTCGAAGCTGCGCCC
GGGCCAGGTCAACCCGACGCTGATCCGCGTGCCGGACGGCTTCGAGATCGTGCGCCTCGTCGATCGCCGCCAGAGCCAGG
GCGCGAGCGCCGCGGCGCCGAAGATCGTCCAGACGCACGTGCGCCATATCCTGCTGCGCGTCGGCGAAGGCAAGTCCGAA
GGCCAGGCGCGCCAGCAACTGGTCGACATCCGCAACCAGGTCGAGGCCGGCGGCGATTTCGCGAAGTTCGCGCGCACCTA
TTCGCAGGACGGTTCCGCGTCGCAGGGCGGCGATCTCGGCTGGATCAGCCCGGGCGAGACCGTGCCGGAATTCGAGCGCG
CGATGAACAACCTGCAGGACGGCCAGATCAGTCAGCCGATTCGTACCGAATACGGCTACCACCTGATCCAGGTGCTGAAC
CGCCGCGAGGCGGAAGGGTCGGTGCAGCAGCAGATGGACATCGCCCGTCAGGCGATCGGCCAGCGCAAGGCCGAGCAGGC
GTATGCCGACTGGCTGCGCGAGCTGCGCGACTCGTCGTACGTGCAGTACAAGATCGGCGGCGTCGGCCCGGCGAACTGA

Upstream 100 bases:

>100_bases
GTTGCCGCCGCCGCCGCCGCCGATGTCCCGCTTCAGCAACTACGAGTAACGCCGGCATGTCTGCACCGGTCAGCACGATT
TCAATGGAGTTCCAGTGGCA

Downstream 100 bases:

>100_bases
GCGAGCATCAATGACCACGCCCGCGCTGCAGATCGCGATCACGACCGGCGAACCCGCGGGAGTCGGCCCGGAGCTGACCG
TGCAGGCGCTGCGTGACGCC

Product: PpiC-type peptidyl-prolyl cis-trans isomerase

Products: NA

Alternate protein names: Peptidyl-prolyl cis-trans isomerase surA; PPIase surA; Rotamase surA

Number of amino acids: Translated: 452; Mature: 452

Protein sequence:

>452_residues
MKKTLRFAAVVSSLAASAALLVAAPAAAQALGSQGAQLADEVVAVVNNDVITGRELDQRVGLIARRLQQQNAPVPPADQL
RAQVLNQMVLERIQVQKAKDDGIRIDDATVQATLQRLAQANGMTLDQYRGRLEAQGVPWSIFTNDARTELMLSKLREREV
DGKITVSDAEVANYIASQRGPNASQQQDLRFQHIFIKAPTNAPQADIEAAQKKADALLQQAKSGADFERLAKNNSEANDA
KKGGDLGFKSPSALPADVVDAASKLRPGQVNPTLIRVPDGFEIVRLVDRRQSQGASAAAPKIVQTHVRHILLRVGEGKSE
GQARQQLVDIRNQVEAGGDFAKFARTYSQDGSASQGGDLGWISPGETVPEFERAMNNLQDGQISQPIRTEYGYHLIQVLN
RREAEGSVQQQMDIARQAIGQRKAEQAYADWLRELRDSSYVQYKIGGVGPAN

Sequences:

>Translated_452_residues
MKKTLRFAAVVSSLAASAALLVAAPAAAQALGSQGAQLADEVVAVVNNDVITGRELDQRVGLIARRLQQQNAPVPPADQL
RAQVLNQMVLERIQVQKAKDDGIRIDDATVQATLQRLAQANGMTLDQYRGRLEAQGVPWSIFTNDARTELMLSKLREREV
DGKITVSDAEVANYIASQRGPNASQQQDLRFQHIFIKAPTNAPQADIEAAQKKADALLQQAKSGADFERLAKNNSEANDA
KKGGDLGFKSPSALPADVVDAASKLRPGQVNPTLIRVPDGFEIVRLVDRRQSQGASAAAPKIVQTHVRHILLRVGEGKSE
GQARQQLVDIRNQVEAGGDFAKFARTYSQDGSASQGGDLGWISPGETVPEFERAMNNLQDGQISQPIRTEYGYHLIQVLN
RREAEGSVQQQMDIARQAIGQRKAEQAYADWLRELRDSSYVQYKIGGVGPAN
>Mature_452_residues
MKKTLRFAAVVSSLAASAALLVAAPAAAQALGSQGAQLADEVVAVVNNDVITGRELDQRVGLIARRLQQQNAPVPPADQL
RAQVLNQMVLERIQVQKAKDDGIRIDDATVQATLQRLAQANGMTLDQYRGRLEAQGVPWSIFTNDARTELMLSKLREREV
DGKITVSDAEVANYIASQRGPNASQQQDLRFQHIFIKAPTNAPQADIEAAQKKADALLQQAKSGADFERLAKNNSEANDA
KKGGDLGFKSPSALPADVVDAASKLRPGQVNPTLIRVPDGFEIVRLVDRRQSQGASAAAPKIVQTHVRHILLRVGEGKSE
GQARQQLVDIRNQVEAGGDFAKFARTYSQDGSASQGGDLGWISPGETVPEFERAMNNLQDGQISQPIRTEYGYHLIQVLN
RREAEGSVQQQMDIARQAIGQRKAEQAYADWLRELRDSSYVQYKIGGVGPAN

Specific function: Chaperone involved in the correct folding and assembly of outer membrane proteins. It recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act

COG id: COG0760

COG function: function code O; Parvulin-like peptidyl-prolyl isomerase

Gene ontology:

Cell location: Periplasm. Note=Is capable of associating with the outer membrane (By similarity)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 PpiC domains

Homologues:

Organism=Escherichia coli, GI1786238, Length=391, Percent_Identity=34.2710997442455, Blast_Score=206, Evalue=3e-54,

Paralogues:

None

Copy number: 400 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 160 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): SURA_BURCA (Q1BTQ6)

Other databases:

- EMBL:   CP000378
- RefSeq:   YP_621972.1
- ProteinModelPortal:   Q1BTQ6
- SMR:   Q1BTQ6
- STRING:   Q1BTQ6
- GeneID:   4091108
- GenomeReviews:   CP000378_GR
- KEGG:   bcn:Bcen_2098
- eggNOG:   COG0760
- HOGENOM:   HBG391483
- OMA:   RHILIKT
- ProtClustDB:   CLSK930370
- BioCyc:   BCEN331271:BCEN_2098-MONOMER
- HAMAP:   MF_01183
- InterPro:   IPR000297
- InterPro:   IPR023034
- InterPro:   IPR015391
- InterPro:   IPR008880

Pfam domain/function: PF00639 Rotamase; PF09312 SurA_N; SSF109998 Trigger_fac_C_bac

EC number: =5.2.1.8

Molecular weight: Translated: 49137; Mature: 49137

Theoretical pI: Translated: 9.14; Mature: 9.14

Prosite motif: PS01096 PPIC_PPIASE_1; PS50198 PPIC_PPIASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKTLRFAAVVSSLAASAALLVAAPAAAQALGSQGAQLADEVVAVVNNDVITGRELDQRV
CCCHHHHHHHHHHHHHHHHHHHHCHHHHHHHHCCCHHHHHHHHHHHCCCCCCCHHHHHHH
GLIARRLQQQNAPVPPADQLRAQVLNQMVLERIQVQKAKDDGIRIDDATVQATLQRLAQA
HHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEECHHHHHHHHHHHHHH
NGMTLDQYRGRLEAQGVPWSIFTNDARTELMLSKLREREVDGKITVSDAEVANYIASQRG
CCCCHHHHCCHHHCCCCCEEEECCCHHHHHHHHHHHHHCCCCCEEECHHHHHHHHHHCCC
PNASQQQDLRFQHIFIKAPTNAPQADIEAAQKKADALLQQAKSGADFERLAKNNSEANDA
CCCCHHHCCEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCCCCHHH
KKGGDLGFKSPSALPADVVDAASKLRPGQVNPTLIRVPDGFEIVRLVDRRQSQGASAAAP
HCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCEEEECCCCHHHHHHHHHHHHCCCCCCCH
KIVQTHVRHILLRVGEGKSEGQARQQLVDIRNQVEAGGDFAKFARTYSQDGSASQGGDLG
HHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCCCCCC
WISPGETVPEFERAMNNLQDGQISQPIRTEYGYHLIQVLNRREAEGSVQQQMDIARQAIG
CCCCCCCCHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
QRKAEQAYADWLRELRDSSYVQYKIGGVGPAN
HHHHHHHHHHHHHHHCCCCEEEEEECCCCCCC
>Mature Secondary Structure
MKKTLRFAAVVSSLAASAALLVAAPAAAQALGSQGAQLADEVVAVVNNDVITGRELDQRV
CCCHHHHHHHHHHHHHHHHHHHHCHHHHHHHHCCCHHHHHHHHHHHCCCCCCCHHHHHHH
GLIARRLQQQNAPVPPADQLRAQVLNQMVLERIQVQKAKDDGIRIDDATVQATLQRLAQA
HHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEECHHHHHHHHHHHHHH
NGMTLDQYRGRLEAQGVPWSIFTNDARTELMLSKLREREVDGKITVSDAEVANYIASQRG
CCCCHHHHCCHHHCCCCCEEEECCCHHHHHHHHHHHHHCCCCCEEECHHHHHHHHHHCCC
PNASQQQDLRFQHIFIKAPTNAPQADIEAAQKKADALLQQAKSGADFERLAKNNSEANDA
CCCCHHHCCEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCCCCHHH
KKGGDLGFKSPSALPADVVDAASKLRPGQVNPTLIRVPDGFEIVRLVDRRQSQGASAAAP
HCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCEEEECCCCHHHHHHHHHHHHCCCCCCCH
KIVQTHVRHILLRVGEGKSEGQARQQLVDIRNQVEAGGDFAKFARTYSQDGSASQGGDLG
HHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCCCCCCC
WISPGETVPEFERAMNNLQDGQISQPIRTEYGYHLIQVLNRREAEGSVQQQMDIARQAIG
CCCCCCCCHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
QRKAEQAYADWLRELRDSSYVQYKIGGVGPAN
HHHHHHHHHHHHHHHCCCCEEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA