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The map label for this gene is xylB [H]

Identifier: 116690606

GI number: 116690606

Start: 2862961

End: 2864442

Strand: Direct

Name: xylB [H]

Synonym: Bcen2424_2586

Alternate gene names: 116690606

Gene position: 2862961-2864442 (Clockwise)

Preceding gene: 116690605

Following gene: 116690607

Centisome position: 82.18

GC content: 72.67

Gene sequence:

>1482_bases
ATGTATCTCGGCATCGACCTCGGCACCTCCGAAGTGAAGGTGCTGCTGCTCGCCCCGGACGGCGCGGTCGTCGGCACCGC
CGGCTCGCCGTTCAGCGTGTCGCGGCCGCATCCGCGCTGGGCGGAACAGCATCCGGACGACTGGTGGCAAGGCACGCTCG
CCGCGCTCGCGGCGCTGCGCGAACGGCACCCGCAGGCGTTCGCGCAGGTGCGCGGCATCGGCCTGTCGGGCCAGATGCAC
GGCGCGGTGCTGCTCGGCCGCGACGATCGCGTGCTGCGCCCCGCGATCCTGTGGAACGACATGCGCAGCGCCGACGAATG
CGCGCTGCTCACCGAACGCGCCCCCGATCTCCATGCGCTGGCCGGCAACCTCGCGATGCCCGGCTTCACCGCGCCGAAAC
TGCTGTGGGTCGCGAAGCACGAACCCGACGTGTTCGCGGCGACCGCGTGCGTGCTGATGCCGAAGGACTACCTGCGCTTC
CGGCTGACCGGCGCGAAAGTGTCCGATCCGTCGGACGCGGCCGGCACGCTGTGGCTCGACGTCGCGCGCCGCGACTGGTC
CGATGCGCTGCTCGCCGCGTGCGGGATGACGCGCGGGCAGATGCCGCGCATCGTCGAGGGCAATGCGCCATCCGGCACGC
TGCGTGCGGACGTCGCACGCGAGTTGGGGTTGTCCGAGGCCGTGCTGGTCGCGGGCGGCGGCGGCGACAACGCGACGAGC
GCGCTCGGCATCGGCGCGATCCACGCGGGCGACGGCTTCGTGTCGCTTGGCACGTCCGGCGTGCTGAGCGTGGTCGGCGA
CCGCTTCATGCCGAATCCCGCGTCGGCCGTGCATGCGTTCTGCCATGCGATTCCCGATCGCTGGCAACTGATGAGCGTCG
TGCTGTCGGCCGCGAGTTGCCTGCGCTGGGTCTGCAAGCTGACCGGCACCGACGAGCCTGCGCTGCTCGCCGAAGTCGAG
GCGCTCGACCCCGACGCGCTCGCCGCCGCCCCGCTGTTCCTGCCCTACCTGTCGGGCGAGCGCACGCCGCACAACGATCC
GTACGCGCAGGGCGTGTTCTTCGGGATGACGCACGCGACCGACCGCGCGCACCTCGGCTATGCGGTACTCGAAGGCGTGA
CGCTGGGCCTCGCCGACGGCCTCGACGCGCTGCACGCGGCCGGCGTCGAGACCGACCAGTTGTCGCTGATCGGCGGCGGC
GCGCGCAGCGCGTTCTGGGCGCAACTGATCGCGGACGCGCTGAACGTGCGCACGCGTCAGCACGGCGGCGGCGAAACCGG
CGCGGCGCTCGGCGCGGCACGGCTCGGCTGGCTGGCCGTCGGCGGCGATCCGCAGACGGTGCTGACCAAACCGCCGGTGC
GCGCCGAATACGCACCGGACGCCGCCCGCCATGCGCGGCTGCGCGAACGCCTCGATGCGTTCCGCACGCTGTACCGTCAC
GTGCGGCCGCTGTACGAACCGTCGCGCGCACGGCTCGCGTAG

Upstream 100 bases:

>100_bases
CCGCGCGCGGCGCCCGGCCGCGCAGCCGGGCGAACCCGCTTGGCACAGGCCGTGCGGCACGGCTAAAGTAGCGGCTCCTC
ACTGACCGAACGGATCGCTC

Downstream 100 bases:

>100_bases
GCGCCGCGCTTACGCGACCGGCCGCCGGCCGTGCGCGCGACATGCGTTACAGTGGATGCCGTCATGCGGCCCGCCGGCCG
GCCCGCGGGGCGGCCCCCAG

Product: xylulokinase

Products: NA

Alternate protein names: Xylulokinase [H]

Number of amino acids: Translated: 493; Mature: 493

Protein sequence:

>493_residues
MYLGIDLGTSEVKVLLLAPDGAVVGTAGSPFSVSRPHPRWAEQHPDDWWQGTLAALAALRERHPQAFAQVRGIGLSGQMH
GAVLLGRDDRVLRPAILWNDMRSADECALLTERAPDLHALAGNLAMPGFTAPKLLWVAKHEPDVFAATACVLMPKDYLRF
RLTGAKVSDPSDAAGTLWLDVARRDWSDALLAACGMTRGQMPRIVEGNAPSGTLRADVARELGLSEAVLVAGGGGDNATS
ALGIGAIHAGDGFVSLGTSGVLSVVGDRFMPNPASAVHAFCHAIPDRWQLMSVVLSAASCLRWVCKLTGTDEPALLAEVE
ALDPDALAAAPLFLPYLSGERTPHNDPYAQGVFFGMTHATDRAHLGYAVLEGVTLGLADGLDALHAAGVETDQLSLIGGG
ARSAFWAQLIADALNVRTRQHGGGETGAALGAARLGWLAVGGDPQTVLTKPPVRAEYAPDAARHARLRERLDAFRTLYRH
VRPLYEPSRARLA

Sequences:

>Translated_493_residues
MYLGIDLGTSEVKVLLLAPDGAVVGTAGSPFSVSRPHPRWAEQHPDDWWQGTLAALAALRERHPQAFAQVRGIGLSGQMH
GAVLLGRDDRVLRPAILWNDMRSADECALLTERAPDLHALAGNLAMPGFTAPKLLWVAKHEPDVFAATACVLMPKDYLRF
RLTGAKVSDPSDAAGTLWLDVARRDWSDALLAACGMTRGQMPRIVEGNAPSGTLRADVARELGLSEAVLVAGGGGDNATS
ALGIGAIHAGDGFVSLGTSGVLSVVGDRFMPNPASAVHAFCHAIPDRWQLMSVVLSAASCLRWVCKLTGTDEPALLAEVE
ALDPDALAAAPLFLPYLSGERTPHNDPYAQGVFFGMTHATDRAHLGYAVLEGVTLGLADGLDALHAAGVETDQLSLIGGG
ARSAFWAQLIADALNVRTRQHGGGETGAALGAARLGWLAVGGDPQTVLTKPPVRAEYAPDAARHARLRERLDAFRTLYRH
VRPLYEPSRARLA
>Mature_493_residues
MYLGIDLGTSEVKVLLLAPDGAVVGTAGSPFSVSRPHPRWAEQHPDDWWQGTLAALAALRERHPQAFAQVRGIGLSGQMH
GAVLLGRDDRVLRPAILWNDMRSADECALLTERAPDLHALAGNLAMPGFTAPKLLWVAKHEPDVFAATACVLMPKDYLRF
RLTGAKVSDPSDAAGTLWLDVARRDWSDALLAACGMTRGQMPRIVEGNAPSGTLRADVARELGLSEAVLVAGGGGDNATS
ALGIGAIHAGDGFVSLGTSGVLSVVGDRFMPNPASAVHAFCHAIPDRWQLMSVVLSAASCLRWVCKLTGTDEPALLAEVE
ALDPDALAAAPLFLPYLSGERTPHNDPYAQGVFFGMTHATDRAHLGYAVLEGVTLGLADGLDALHAAGVETDQLSLIGGG
ARSAFWAQLIADALNVRTRQHGGGETGAALGAARLGWLAVGGDPQTVLTKPPVRAEYAPDAARHARLRERLDAFRTLYRH
VRPLYEPSRARLA

Specific function: Unknown

COG id: COG1070

COG function: function code G; Sugar (pentulose and hexulose) kinases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FGGY kinase family [H]

Homologues:

Organism=Homo sapiens, GI42794763, Length=438, Percent_Identity=22.6027397260274, Blast_Score=100, Evalue=5e-21,
Organism=Homo sapiens, GI4504007, Length=438, Percent_Identity=22.8310502283105, Blast_Score=97, Evalue=3e-20,
Organism=Homo sapiens, GI189409120, Length=438, Percent_Identity=22.8310502283105, Blast_Score=97, Evalue=3e-20,
Organism=Homo sapiens, GI41393575, Length=405, Percent_Identity=21.7283950617284, Blast_Score=88, Evalue=2e-17,
Organism=Escherichia coli, GI1789987, Length=488, Percent_Identity=52.4590163934426, Blast_Score=480, Evalue=1e-136,
Organism=Escherichia coli, GI1790005, Length=486, Percent_Identity=26.5432098765432, Blast_Score=128, Evalue=1e-30,
Organism=Escherichia coli, GI1789168, Length=448, Percent_Identity=27.0089285714286, Blast_Score=115, Evalue=5e-27,
Organism=Escherichia coli, GI1790361, Length=478, Percent_Identity=22.5941422594142, Blast_Score=107, Evalue=2e-24,
Organism=Escherichia coli, GI1787789, Length=373, Percent_Identity=24.6648793565684, Blast_Score=95, Evalue=8e-21,
Organism=Caenorhabditis elegans, GI17535599, Length=452, Percent_Identity=23.2300884955752, Blast_Score=92, Evalue=9e-19,
Organism=Saccharomyces cerevisiae, GI6321633, Length=332, Percent_Identity=25, Blast_Score=87, Evalue=8e-18,
Organism=Drosophila melanogaster, GI24657106, Length=468, Percent_Identity=22.4358974358974, Blast_Score=75, Evalue=8e-14,
Organism=Drosophila melanogaster, GI24657102, Length=468, Percent_Identity=22.4358974358974, Blast_Score=75, Evalue=8e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000577
- InterPro:   IPR018485
- InterPro:   IPR018483
- InterPro:   IPR018484
- InterPro:   IPR006000 [H]

Pfam domain/function: PF02782 FGGY_C; PF00370 FGGY_N [H]

EC number: =2.7.1.17 [H]

Molecular weight: Translated: 52201; Mature: 52201

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: PS00933 FGGY_KINASES_1 ; PS00445 FGGY_KINASES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYLGIDLGTSEVKVLLLAPDGAVVGTAGSPFSVSRPHPRWAEQHPDDWWQGTLAALAALR
CEEEEECCCCCEEEEEECCCCCEEECCCCCCCCCCCCCCHHHCCCCHHHHHHHHHHHHHH
ERHPQAFAQVRGIGLSGQMHGAVLLGRDDRVLRPAILWNDMRSADECALLTERAPDLHAL
HHCHHHHHHHHCCCCCCCCCCEEEECCCCCCCCHHHHHHHCCCCHHHHHHHCCCCCHHHH
AGNLAMPGFTAPKLLWVAKHEPDVFAATACVLMPKDYLRFRLTGAKVSDPSDAAGTLWLD
HCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHCCCHHEEEEEECCCCCCCCCCCCEEEEE
VARRDWSDALLAACGMTRGQMPRIVEGNAPSGTLRADVARELGLSEAVLVAGGGGDNATS
EHHCCHHHHHHHHHCCCCCCCCCEEECCCCCCCHHHHHHHHCCCCCEEEEEECCCCCCCH
ALGIGAIHAGDGFVSLGTSGVLSVVGDRFMPNPASAVHAFCHAIPDRWQLMSVVLSAASC
HHEEEEEECCCCEEECCCCHHHHHHCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHH
LRWVCKLTGTDEPALLAEVEALDPDALAAAPLFLPYLSGERTPHNDPYAQGVFFGMTHAT
HHHHHHHCCCCCCHHHHEECCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEECCCC
DRAHLGYAVLEGVTLGLADGLDALHAAGVETDQLSLIGGGARSAFWAQLIADALNVRTRQ
CCHHHHHHHHHHHHHHHHCCHHHHHHCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHC
HGGGETGAALGAARLGWLAVGGDPQTVLTKPPVRAEYAPDAARHARLRERLDAFRTLYRH
CCCCCCHHHHHHHHHCEEEECCCCCEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
VRPLYEPSRARLA
HHHCCCCCCCCCC
>Mature Secondary Structure
MYLGIDLGTSEVKVLLLAPDGAVVGTAGSPFSVSRPHPRWAEQHPDDWWQGTLAALAALR
CEEEEECCCCCEEEEEECCCCCEEECCCCCCCCCCCCCCHHHCCCCHHHHHHHHHHHHHH
ERHPQAFAQVRGIGLSGQMHGAVLLGRDDRVLRPAILWNDMRSADECALLTERAPDLHAL
HHCHHHHHHHHCCCCCCCCCCEEEECCCCCCCCHHHHHHHCCCCHHHHHHHCCCCCHHHH
AGNLAMPGFTAPKLLWVAKHEPDVFAATACVLMPKDYLRFRLTGAKVSDPSDAAGTLWLD
HCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHCCCHHEEEEEECCCCCCCCCCCCEEEEE
VARRDWSDALLAACGMTRGQMPRIVEGNAPSGTLRADVARELGLSEAVLVAGGGGDNATS
EHHCCHHHHHHHHHCCCCCCCCCEEECCCCCCCHHHHHHHHCCCCCEEEEEECCCCCCCH
ALGIGAIHAGDGFVSLGTSGVLSVVGDRFMPNPASAVHAFCHAIPDRWQLMSVVLSAASC
HHEEEEEECCCCEEECCCCHHHHHHCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHH
LRWVCKLTGTDEPALLAEVEALDPDALAAAPLFLPYLSGERTPHNDPYAQGVFFGMTHAT
HHHHHHHCCCCCCHHHHEECCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEECCCC
DRAHLGYAVLEGVTLGLADGLDALHAAGVETDQLSLIGGGARSAFWAQLIADALNVRTRQ
CCHHHHHHHHHHHHHHHHCCHHHHHHCCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHC
HGGGETGAALGAARLGWLAVGGDPQTVLTKPPVRAEYAPDAARHARLRERLDAFRTLYRH
CCCCCCHHHHHHHHHCEEEECCCCCEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHH
VRPLYEPSRARLA
HHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 6320721; 8041620; 9278503 [H]