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The map label for this gene is dalD [H]

Identifier: 116690605

GI number: 116690605

Start: 2861462

End: 2862856

Strand: Direct

Name: dalD [H]

Synonym: Bcen2424_2585

Alternate gene names: 116690605

Gene position: 2861462-2862856 (Clockwise)

Preceding gene: 116690604

Following gene: 116690606

Centisome position: 82.13

GC content: 70.9

Gene sequence:

>1395_bases
ATGAGCGAATCGCCCGCCGCCCACGCGCCCGTGCTGCTGCACATCGGCGCGGGCTCGTTTCACCGCGCGCACCAGGCGTG
GTATCTGCATCGCGTGAACGCGGCCGTGCCGGCCGACGAACGCTGGTCGCTAACCGTCGGCAACATCCGCGACGACATGC
GCGCGACGATGGACGCGCTCGCCGCGCAGCACGGTGCGTACACGCTCGAAACCGTCACGCCGCAAGGCGAGCGCGCGTAC
GAGACGATCCGTGCGATCACGCGCGTGCTGCCGTGGTCGATCGACCTCGCCGCGCTGATCGACGCCGGCGCCGATCCGGC
CTGCCGGATCGTGTCGTTCACCGTCACCGAAGGCGGCTACTACCTCGACGAACACAACCGGCTCGACATCGCGAACGCCG
ATCTCGCCGCCGACCTGCAGGGCGCACGCACGACGCTGTACGGCGCGCTCGCCGCGCTGCTCGCCGAACGCGTGAAGCGC
GGCGCGGGGCCGCTCACGCTGCAAAGCTGCGACAACCTGCGCAACAACGGCGCACGGTTTCGCGCGGGGATGCGCGAATT
CCTCGAACGGCGCGGCGAAGGCGGCCTGCTCGCATGGTTCGATGCGCACGTCGCGACGCCCAGCGCGATGGTCGACCGCA
TCACGCCGCGCCCGACCGCCGACGTGCGCGAGCGCGTCCTCGCGGCCACCGGCATCGACGACGCGTGCCCGGTGATGGGC
GAATCGTTCATCCAGTGGGTGATCGAGGACCGCTTCGCGGCCGGTCGCCCGCGCTGGGAGCTGGCCGGCGCCGAACTCGT
CGACGACGTGCATCCGTACGAGGAAGCGAAGATCCGCATCCTCAACGCGACGCACAGCTGCATCGCATGGGCCGGCACGC
TCGCGGGCCATACCTACATCCACGAAGGCACGCACGACCCGGCGATCCGCCGCTTCGCGCACGACTACGTGACGCAGGAC
GTGATCCCGTGCCTCACGCCGAGCCCGCTCGATCTCGCACGCTATCGCGACGTCGTGCTGGAGCGCTTCGGCAATCCGTA
CGTGCTCGACACGAACCAGCGGGTCGCGGCCGACGGTTTCTCGAAGATCCCCGGCTTCATCGCGCCGACGCTCGTCGAAT
CGTTCGCTCGCGGCGCGGCACCCGTCGCCACCGCCGTGCTGCCCGCGCTGTTCCTGCGCTTTCTCGAACGCTGGGCGCGC
GGCACGCTGCCATATGCGTACCAGGACGGCGTGATGGACGACGGCAGCGCACGCGCGATCGTCGAAGCCGACGACCCGGT
CGTCGCGTTGTGCGCGAGCCGCGCCTTGTGGGGCTCGCTCGCCGGCAACGCGGCGCTGTTCGACGCGCTGCGCGCCGGGC
TCGCGCGCGTCGACGCCTGGCTCACCGCCCGCTGA

Upstream 100 bases:

>100_bases
CCCGCCTTGACTTTCGTCCGCCTGAATACGATCATTCGCTCACACAAAGAGCAAAAGATCGTATTCGGCAGGATAGACAG
GCTGGAACAGGAGACACCGG

Downstream 100 bases:

>100_bases
TGACCCGCGCGCGGCGCCCGGCCGCGCAGCCGGGCGAACCCGCTTGGCACAGGCCGTGCGGCACGGCTAAAGTAGCGGCT
CCTCACTGACCGAACGGATC

Product: mannitol dehydrogenase domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 464; Mature: 463

Protein sequence:

>464_residues
MSESPAAHAPVLLHIGAGSFHRAHQAWYLHRVNAAVPADERWSLTVGNIRDDMRATMDALAAQHGAYTLETVTPQGERAY
ETIRAITRVLPWSIDLAALIDAGADPACRIVSFTVTEGGYYLDEHNRLDIANADLAADLQGARTTLYGALAALLAERVKR
GAGPLTLQSCDNLRNNGARFRAGMREFLERRGEGGLLAWFDAHVATPSAMVDRITPRPTADVRERVLAATGIDDACPVMG
ESFIQWVIEDRFAAGRPRWELAGAELVDDVHPYEEAKIRILNATHSCIAWAGTLAGHTYIHEGTHDPAIRRFAHDYVTQD
VIPCLTPSPLDLARYRDVVLERFGNPYVLDTNQRVAADGFSKIPGFIAPTLVESFARGAAPVATAVLPALFLRFLERWAR
GTLPYAYQDGVMDDGSARAIVEADDPVVALCASRALWGSLAGNAALFDALRAGLARVDAWLTAR

Sequences:

>Translated_464_residues
MSESPAAHAPVLLHIGAGSFHRAHQAWYLHRVNAAVPADERWSLTVGNIRDDMRATMDALAAQHGAYTLETVTPQGERAY
ETIRAITRVLPWSIDLAALIDAGADPACRIVSFTVTEGGYYLDEHNRLDIANADLAADLQGARTTLYGALAALLAERVKR
GAGPLTLQSCDNLRNNGARFRAGMREFLERRGEGGLLAWFDAHVATPSAMVDRITPRPTADVRERVLAATGIDDACPVMG
ESFIQWVIEDRFAAGRPRWELAGAELVDDVHPYEEAKIRILNATHSCIAWAGTLAGHTYIHEGTHDPAIRRFAHDYVTQD
VIPCLTPSPLDLARYRDVVLERFGNPYVLDTNQRVAADGFSKIPGFIAPTLVESFARGAAPVATAVLPALFLRFLERWAR
GTLPYAYQDGVMDDGSARAIVEADDPVVALCASRALWGSLAGNAALFDALRAGLARVDAWLTAR
>Mature_463_residues
SESPAAHAPVLLHIGAGSFHRAHQAWYLHRVNAAVPADERWSLTVGNIRDDMRATMDALAAQHGAYTLETVTPQGERAYE
TIRAITRVLPWSIDLAALIDAGADPACRIVSFTVTEGGYYLDEHNRLDIANADLAADLQGARTTLYGALAALLAERVKRG
AGPLTLQSCDNLRNNGARFRAGMREFLERRGEGGLLAWFDAHVATPSAMVDRITPRPTADVRERVLAATGIDDACPVMGE
SFIQWVIEDRFAAGRPRWELAGAELVDDVHPYEEAKIRILNATHSCIAWAGTLAGHTYIHEGTHDPAIRRFAHDYVTQDV
IPCLTPSPLDLARYRDVVLERFGNPYVLDTNQRVAADGFSKIPGFIAPTLVESFARGAAPVATAVLPALFLRFLERWARG
TLPYAYQDGVMDDGSARAIVEADDPVVALCASRALWGSLAGNAALFDALRAGLARVDAWLTAR

Specific function: Unknown

COG id: COG0246

COG function: function code G; Mannitol-1-phosphate/altronate dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mannitol dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI1788497, Length=357, Percent_Identity=36.1344537815126, Blast_Score=212, Evalue=3e-56,
Organism=Escherichia coli, GI1790779, Length=361, Percent_Identity=34.9030470914127, Blast_Score=200, Evalue=1e-52,
Organism=Escherichia coli, GI1787823, Length=450, Percent_Identity=32, Blast_Score=195, Evalue=6e-51,
Organism=Escherichia coli, GI48994885, Length=404, Percent_Identity=24.7524752475248, Blast_Score=88, Evalue=1e-18,
Organism=Escherichia coli, GI1790028, Length=367, Percent_Identity=24.5231607629428, Blast_Score=78, Evalue=9e-16,
Organism=Saccharomyces cerevisiae, GI6324401, Length=423, Percent_Identity=37.5886524822695, Blast_Score=262, Evalue=8e-71,
Organism=Saccharomyces cerevisiae, GI6320765, Length=423, Percent_Identity=37.5886524822695, Blast_Score=262, Evalue=8e-71,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008927
- InterPro:   IPR013328
- InterPro:   IPR000669
- InterPro:   IPR013118
- InterPro:   IPR013131
- InterPro:   IPR016040 [H]

Pfam domain/function: PF01232 Mannitol_dh; PF08125 Mannitol_dh_C [H]

EC number: =1.1.1.11 [H]

Molecular weight: Translated: 50495; Mature: 50363

Theoretical pI: Translated: 5.88; Mature: 5.88

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSESPAAHAPVLLHIGAGSFHRAHQAWYLHRVNAAVPADERWSLTVGNIRDDMRATMDAL
CCCCCCCCCCEEEEECCCCHHHHHHHHHHEECCCCCCCCCCCEEEECCHHHHHHHHHHHH
AAQHGAYTLETVTPQGERAYETIRAITRVLPWSIDLAALIDAGADPACRIVSFTVTEGGY
HHHCCCEEEEEECCCCHHHHHHHHHHHHHCCCCCCHHHHHCCCCCCCEEEEEEEEECCCE
YLDEHNRLDIANADLAADLQGARTTLYGALAALLAERVKRGAGPLTLQSCDNLRNNGARF
EECCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEHHHHHHHHCCCHHH
RAGMREFLERRGEGGLLAWFDAHVATPSAMVDRITPRPTADVRERVLAATGIDDACPVMG
HHHHHHHHHHCCCCCEEEEEECHHCCHHHHHHCCCCCCCHHHHHHHHHHCCCCCCCHHHH
ESFIQWVIEDRFAAGRPRWELAGAELVDDVHPYEEAKIRILNATHSCIAWAGTLAGHTYI
HHHHHHHHHHHHHCCCCCCEECCHHHHHHCCCCCCCEEEEEECCHHHHHHHHHHHCCCEE
HEGTHDPAIRRFAHDYVTQDVIPCLTPSPLDLARYRDVVLERFGNPYVLDTNQRVAADGF
ECCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCEEEECCCCHHHCCH
SKIPGFIAPTLVESFARGAAPVATAVLPALFLRFLERWARGTLPYAYQDGVMDDGSARAI
HHCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEE
VEADDPVVALCASRALWGSLAGNAALFDALRAGLARVDAWLTAR
EECCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SESPAAHAPVLLHIGAGSFHRAHQAWYLHRVNAAVPADERWSLTVGNIRDDMRATMDAL
CCCCCCCCCEEEEECCCCHHHHHHHHHHEECCCCCCCCCCCEEEECCHHHHHHHHHHHH
AAQHGAYTLETVTPQGERAYETIRAITRVLPWSIDLAALIDAGADPACRIVSFTVTEGGY
HHHCCCEEEEEECCCCHHHHHHHHHHHHHCCCCCCHHHHHCCCCCCCEEEEEEEEECCCE
YLDEHNRLDIANADLAADLQGARTTLYGALAALLAERVKRGAGPLTLQSCDNLRNNGARF
EECCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEHHHHHHHHCCCHHH
RAGMREFLERRGEGGLLAWFDAHVATPSAMVDRITPRPTADVRERVLAATGIDDACPVMG
HHHHHHHHHHCCCCCEEEEEECHHCCHHHHHHCCCCCCCHHHHHHHHHHCCCCCCCHHHH
ESFIQWVIEDRFAAGRPRWELAGAELVDDVHPYEEAKIRILNATHSCIAWAGTLAGHTYI
HHHHHHHHHHHHHCCCCCCEECCHHHHHHCCCCCCCEEEEEECCHHHHHHHHHHHCCCEE
HEGTHDPAIRRFAHDYVTQDVIPCLTPSPLDLARYRDVVLERFGNPYVLDTNQRVAADGF
ECCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCEEEECCCCHHHCCH
SKIPGFIAPTLVESFARGAAPVATAVLPALFLRFLERWARGTLPYAYQDGVMDDGSARAI
HHCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEE
VEADDPVVALCASRALWGSLAGNAALFDALRAGLARVDAWLTAR
EECCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11823852 [H]