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The map label for this gene is lsrR [H]

Identifier: 116690607

GI number: 116690607

Start: 2864506

End: 2865519

Strand: Direct

Name: lsrR [H]

Synonym: Bcen2424_2587

Alternate gene names: 116690607

Gene position: 2864506-2865519 (Clockwise)

Preceding gene: 116690606

Following gene: 116690610

Centisome position: 82.22

GC content: 70.32

Gene sequence:

>1014_bases
ATGCGGCCCGCCGGCCGGCCCGCGGGGCGGCCCCCAGATCCGAACCGAATCGCTATCGTGTCCAAGTCCTCAGAAAAACT
CGATCTCGCCACGCGCGCCGCGTGGCTCTACTACGTCGCGGGCGACACGCAGAACGAAATCGCCGAAAAACTGCAGGTGT
CGCGCCCCGTCGCGCAGCGCCTCGTCGCGTTCGCGGTCGAGAAGAACCTGATCCGCGTGCGCGTCGACCATCGACTCGCC
GACTGCCTCGATCTCGGCGCGCAGCTGTCGAAACGCTACGGCCTCGCGATGTGCGAGGTCGTGCCCGTCGACGCCGATGC
GCCCGACGCGATCGACCGCAAGCTCGCGGTCGCCGGCGCGCAGGTGATGGAGCGCTACCTGAACGAAACACGGCCGATGG
TGATCGCGGTCAGCAGCGGCCGGACGCTGAAGGCCGCGGTCGCGCAGATCGCGCAGATCGACCGCCCGCAGCACCGGCTC
GTGTCGATGGTCGGCGCGATCGCGGCCGACGGCTCGTCGAACCGCTACGACGTCGCGCAGTACATCTCCGAGAAAACCGG
CAGCAAGCACTTCCTGCTGCCCGCGCCGCTGTTCGCGGATAGCGACGCCGAGCGCGCGCAGTGGTGCAATCACCGGCTGT
ACCGGATCGTCGAGGCGCTGTCGGGCGAGGCCGACGTCGCGTTCGTCGGGATCGGCAACATCGGCCCGCACTGCCCGCTC
TACGAAGACGGCTTCATCACCGAACAGGAGCGCGACGAGATGACCGCGCTCGGCGCGGTGGCCGAACTGCTCGGCGTGCC
GATCGACGCGCAGGGCACGCAGATCACCGTGTCGACCAGCGCGCGCGTGACGAGCGTCGCGCTCGCCACGCCGCCGAAGC
TGCCGACGATCGCGTTCGCCGGCGGCCCGAAGAAACACGACGCGGTGATTGCCGCGCTGCGCGGCGGCTGGCTGTCGGGG
CTCGTCACCGACGAAGCCTGCGCGCGCGCCGCGCTCGCCGCGAAGGCGGCCTGA

Upstream 100 bases:

>100_bases
GCCGCTGTACGAACCGTCGCGCGCACGGCTCGCGTAGGCGCCGCGCTTACGCGACCGGCCGCCGGCCGTGCGCGCGACAT
GCGTTACAGTGGATGCCGTC

Downstream 100 bases:

>100_bases
CGCGGCCGTCGCCCGCACGGGTTCAGGCCGCGCGCGGCGCCGGAAACGCATGGCGGCGTGCGCGCCACGCGCCGACCCAC
GCCAGCGCCAGCAGCGCGAC

Product: DeoR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 337; Mature: 337

Protein sequence:

>337_residues
MRPAGRPAGRPPDPNRIAIVSKSSEKLDLATRAAWLYYVAGDTQNEIAEKLQVSRPVAQRLVAFAVEKNLIRVRVDHRLA
DCLDLGAQLSKRYGLAMCEVVPVDADAPDAIDRKLAVAGAQVMERYLNETRPMVIAVSSGRTLKAAVAQIAQIDRPQHRL
VSMVGAIAADGSSNRYDVAQYISEKTGSKHFLLPAPLFADSDAERAQWCNHRLYRIVEALSGEADVAFVGIGNIGPHCPL
YEDGFITEQERDEMTALGAVAELLGVPIDAQGTQITVSTSARVTSVALATPPKLPTIAFAGGPKKHDAVIAALRGGWLSG
LVTDEACARAALAAKAA

Sequences:

>Translated_337_residues
MRPAGRPAGRPPDPNRIAIVSKSSEKLDLATRAAWLYYVAGDTQNEIAEKLQVSRPVAQRLVAFAVEKNLIRVRVDHRLA
DCLDLGAQLSKRYGLAMCEVVPVDADAPDAIDRKLAVAGAQVMERYLNETRPMVIAVSSGRTLKAAVAQIAQIDRPQHRL
VSMVGAIAADGSSNRYDVAQYISEKTGSKHFLLPAPLFADSDAERAQWCNHRLYRIVEALSGEADVAFVGIGNIGPHCPL
YEDGFITEQERDEMTALGAVAELLGVPIDAQGTQITVSTSARVTSVALATPPKLPTIAFAGGPKKHDAVIAALRGGWLSG
LVTDEACARAALAAKAA
>Mature_337_residues
MRPAGRPAGRPPDPNRIAIVSKSSEKLDLATRAAWLYYVAGDTQNEIAEKLQVSRPVAQRLVAFAVEKNLIRVRVDHRLA
DCLDLGAQLSKRYGLAMCEVVPVDADAPDAIDRKLAVAGAQVMERYLNETRPMVIAVSSGRTLKAAVAQIAQIDRPQHRL
VSMVGAIAADGSSNRYDVAQYISEKTGSKHFLLPAPLFADSDAERAQWCNHRLYRIVEALSGEADVAFVGIGNIGPHCPL
YEDGFITEQERDEMTALGAVAELLGVPIDAQGTQITVSTSARVTSVALATPPKLPTIAFAGGPKKHDAVIAALRGGWLSG
LVTDEACARAALAAKAA

Specific function: Regulates transcription of many different genes. In the absence of autoinducer 2 (AI-2), represses transcription of the lsrACDBFG operon and its own transcription. In the presence of AI- 2, lsrR is inactivated by binding phospho-AI-2, leading to the trans

COG id: COG2390

COG function: function code K; Transcriptional regulator, contains sigma factor-related N-terminal domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sorC transcriptional regulatory family [H]

Homologues:

Organism=Escherichia coli, GI1787791, Length=305, Percent_Identity=28.5245901639344, Blast_Score=113, Evalue=2e-26,
Organism=Escherichia coli, GI87082414, Length=316, Percent_Identity=24.6835443037975, Blast_Score=87, Evalue=1e-18,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007324
- InterPro:   IPR011991 [H]

Pfam domain/function: PF04198 Sugar-bind [H]

EC number: NA

Molecular weight: Translated: 35966; Mature: 35966

Theoretical pI: Translated: 7.50; Mature: 7.50

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRPAGRPAGRPPDPNRIAIVSKSSEKLDLATRAAWLYYVAGDTQNEIAEKLQVSRPVAQR
CCCCCCCCCCCCCCCEEEEEECCCCHHHHHHHEEEEEEEECCCHHHHHHHHHHHHHHHHH
LVAFAVEKNLIRVRVDHRLADCLDLGAQLSKRYGLAMCEVVPVDADAPDAIDRKLAVAGA
HHHHHHHCCEEEEEHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCHHHHHHHHHHHH
QVMERYLNETRPMVIAVSSGRTLKAAVAQIAQIDRPQHRLVSMVGAIAADGSSNRYDVAQ
HHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCHHHHH
YISEKTGSKHFLLPAPLFADSDAERAQWCNHRLYRIVEALSGEADVAFVGIGNIGPHCPL
HHHHHCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCC
YEDGFITEQERDEMTALGAVAELLGVPIDAQGTQITVSTSARVTSVALATPPKLPTIAFA
CCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCEEEEEEECCCCCCEEEEC
GGPKKHDAVIAALRGGWLSGLVTDEACARAALAAKAA
CCCCHHHHHHHHHHCCHHHCCCCHHHHHHHHHHHCCC
>Mature Secondary Structure
MRPAGRPAGRPPDPNRIAIVSKSSEKLDLATRAAWLYYVAGDTQNEIAEKLQVSRPVAQR
CCCCCCCCCCCCCCCEEEEEECCCCHHHHHHHEEEEEEEECCCHHHHHHHHHHHHHHHHH
LVAFAVEKNLIRVRVDHRLADCLDLGAQLSKRYGLAMCEVVPVDADAPDAIDRKLAVAGA
HHHHHHHCCEEEEEHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCCHHHHHHHHHHHH
QVMERYLNETRPMVIAVSSGRTLKAAVAQIAQIDRPQHRLVSMVGAIAADGSSNRYDVAQ
HHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCHHHHH
YISEKTGSKHFLLPAPLFADSDAERAQWCNHRLYRIVEALSGEADVAFVGIGNIGPHCPL
HHHHHCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCC
YEDGFITEQERDEMTALGAVAELLGVPIDAQGTQITVSTSARVTSVALATPPKLPTIAFA
CCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCEEEEEEECCCCCCEEEEC
GGPKKHDAVIAALRGGWLSGLVTDEACARAALAAKAA
CCCCHHHHHHHHHHCCHHHCCCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA