Click here to switch to the map view.

The map label for this gene is xerD [H]

Identifier: 116690579

GI number: 116690579

Start: 2834754

End: 2835710

Strand: Reverse

Name: xerD [H]

Synonym: Bcen2424_2559

Alternate gene names: 116690579

Gene position: 2835710-2834754 (Counterclockwise)

Preceding gene: 116690580

Following gene: 116690577

Centisome position: 81.39

GC content: 70.64

Gene sequence:

>957_bases
ATGAGCGAACCGATGATTTCCCCCGCCGCCGACAACGACACCGACGCCGTCGCGGCATCGCCCGCGCTGCTCGCGAGCCG
CGCGTCGATCGACGTGTTCTGCGATGCGCTGTGGCTCGAGCACGGGCTCGCGCGCAACACGCTCGATGCGTACCGGCGCG
ACCTGGCGCTGTTTTCCCAATGGCTGGCCGCGACGCACGACGCGCCGCTCGACTCGGCCGACGAGGCGATGGTGACGGGC
TATATCGCCGCGCGCAGCGACGGCAAGGCGACGTCGTCGAACCGGCGGTTGTCCGTGTTCCGCCGCTATTACGGCTGGGC
CGTGCGCGAGCATCGCGCGAGCGCCGATCCGACGCTGCGGATCACGTCCGCGAAACAGGGGGCCCGGTTCCCGTCGACGC
TGTCCGAGGCGCAGGTCGAGGCGCTGCTCGGCGCACCCGACATCGGCACGCCGCTCGGCCTGCGCGATCGCACGATGCTC
GAGCTGATGTACGCGAGCGGGCTGCGCGTGAGCGAGCTCGTGACGCTGAAGACGGTCGAGGTCGGCCTCAACGAAGGCGT
CGTGCGCGTGATGGGCAAGGGCTCGAAGGAGCGGCTCGTGCCGTTCGGCGAAGTCGCGCACGGCTGGATCGAACGCTACC
TGCGCGACGCGCGGCCGGCGCTGCTCGGCGCACGCGCGGCCGATGCGCTGTTCGTGACCGCGCGCGGCGACGGCATGACG
CGCCAGCAGTTCTGGAACATCATCAAGCGTCACGCGCAGCAGGCCGACGTGCGTGCGCACCTGTCGCCGCACACGCTGCG
GCACGCGTTCGCGACGCACCTGCTGAACCACGGCGCCGACTTGCGCGTCGTGCAGTTGCTGCTCGGCCACAGCGACATCT
CGACCACGCAGATCTATACGCACGTCGCGCGCGAGCGGCTCAGGACGCTGCACGCGCAGCATCACCCGCGCGGCTGA

Upstream 100 bases:

>100_bases
TCGCGGCGGGCGGTCTCGGCGGATTCGCGAACCACGACGACAACGGCTATTACCAGCAAGTGAAGCGCTGGCTGCTGACG
CACGAGGGCGTGCCGTACTG

Downstream 100 bases:

>100_bases
CGCGCGACGCGGGCATGCGGCTCGGCGTGAGCCGCAATGTGGACTCGCGTGCCGTCGCGTCGGCCGCGTCAGACCAGCTC
GCGCAGCCGGTGCTTCAGCA

Product: site-specific tyrosine recombinase XerD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 318; Mature: 317

Protein sequence:

>318_residues
MSEPMISPAADNDTDAVAASPALLASRASIDVFCDALWLEHGLARNTLDAYRRDLALFSQWLAATHDAPLDSADEAMVTG
YIAARSDGKATSSNRRLSVFRRYYGWAVREHRASADPTLRITSAKQGARFPSTLSEAQVEALLGAPDIGTPLGLRDRTML
ELMYASGLRVSELVTLKTVEVGLNEGVVRVMGKGSKERLVPFGEVAHGWIERYLRDARPALLGARAADALFVTARGDGMT
RQQFWNIIKRHAQQADVRAHLSPHTLRHAFATHLLNHGADLRVVQLLLGHSDISTTQIYTHVARERLRTLHAQHHPRG

Sequences:

>Translated_318_residues
MSEPMISPAADNDTDAVAASPALLASRASIDVFCDALWLEHGLARNTLDAYRRDLALFSQWLAATHDAPLDSADEAMVTG
YIAARSDGKATSSNRRLSVFRRYYGWAVREHRASADPTLRITSAKQGARFPSTLSEAQVEALLGAPDIGTPLGLRDRTML
ELMYASGLRVSELVTLKTVEVGLNEGVVRVMGKGSKERLVPFGEVAHGWIERYLRDARPALLGARAADALFVTARGDGMT
RQQFWNIIKRHAQQADVRAHLSPHTLRHAFATHLLNHGADLRVVQLLLGHSDISTTQIYTHVARERLRTLHAQHHPRG
>Mature_317_residues
SEPMISPAADNDTDAVAASPALLASRASIDVFCDALWLEHGLARNTLDAYRRDLALFSQWLAATHDAPLDSADEAMVTGY
IAARSDGKATSSNRRLSVFRRYYGWAVREHRASADPTLRITSAKQGARFPSTLSEAQVEALLGAPDIGTPLGLRDRTMLE
LMYASGLRVSELVTLKTVEVGLNEGVVRVMGKGSKERLVPFGEVAHGWIERYLRDARPALLGARAADALFVTARGDGMTR
QQFWNIIKRHAQQADVRAHLSPHTLRHAFATHLLNHGADLRVVQLLLGHSDISTTQIYTHVARERLRTLHAQHHPRG

Specific function: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The xerC-xerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell div

COG id: COG4974

COG function: function code L; Site-specific recombinase XerD

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'phage' integrase family. XerD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789261, Length=294, Percent_Identity=56.8027210884354, Blast_Score=307, Evalue=6e-85,
Organism=Escherichia coli, GI1790244, Length=294, Percent_Identity=38.4353741496599, Blast_Score=167, Evalue=7e-43,
Organism=Escherichia coli, GI1790768, Length=168, Percent_Identity=33.9285714285714, Blast_Score=86, Evalue=5e-18,
Organism=Escherichia coli, GI1790767, Length=172, Percent_Identity=27.906976744186, Blast_Score=73, Evalue=3e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011010
- InterPro:   IPR013762
- InterPro:   IPR002104
- InterPro:   IPR010998
- InterPro:   IPR023109
- InterPro:   IPR004107
- InterPro:   IPR011932 [H]

Pfam domain/function: PF02899 Phage_integr_N; PF00589 Phage_integrase [H]

EC number: NA

Molecular weight: Translated: 35017; Mature: 34886

Theoretical pI: Translated: 9.62; Mature: 9.62

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEPMISPAADNDTDAVAASPALLASRASIDVFCDALWLEHGLARNTLDAYRRDLALFSQ
CCCCCCCCCCCCCCCHHHCCHHHHHHCCHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHH
WLAATHDAPLDSADEAMVTGYIAARSDGKATSSNRRLSVFRRYYGWAVREHRASADPTLR
HHHHCCCCCCCCCCHHHHHHEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEE
ITSAKQGARFPSTLSEAQVEALLGAPDIGTPLGLRDRTMLELMYASGLRVSELVTLKTVE
EECCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHEE
VGLNEGVVRVMGKGSKERLVPFGEVAHGWIERYLRDARPALLGARAADALFVTARGDGMT
CCCCCCHHEECCCCCHHHCCCHHHHHHHHHHHHHHHCCHHHHHCCCCCEEEEEECCCCCC
RQQFWNIIKRHAQQADVRAHLSPHTLRHAFATHLLNHGADLRVVQLLLGHSDISTTQIYT
HHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCHHHHHH
HVARERLRTLHAQHHPRG
HHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
SEPMISPAADNDTDAVAASPALLASRASIDVFCDALWLEHGLARNTLDAYRRDLALFSQ
CCCCCCCCCCCCCCHHHCCHHHHHHCCHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHH
WLAATHDAPLDSADEAMVTGYIAARSDGKATSSNRRLSVFRRYYGWAVREHRASADPTLR
HHHHCCCCCCCCCCHHHHHHEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEE
ITSAKQGARFPSTLSEAQVEALLGAPDIGTPLGLRDRTMLELMYASGLRVSELVTLKTVE
EECCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHEE
VGLNEGVVRVMGKGSKERLVPFGEVAHGWIERYLRDARPALLGARAADALFVTARGDGMT
CCCCCCHHEECCCCCHHHCCCHHHHHHHHHHHHHHHCCHHHHHCCCCCEEEEEECCCCCC
RQQFWNIIKRHAQQADVRAHLSPHTLRHAFATHLLNHGADLRVVQLLLGHSDISTTQIYT
HHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCHHHHHHHHCCCCCCHHHHHH
HVARERLRTLHAQHHPRG
HHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11823852 [H]