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The map label for this gene is htpG

Identifier: 116690367

GI number: 116690367

Start: 2607396

End: 2609294

Strand: Reverse

Name: htpG

Synonym: Bcen2424_2347

Alternate gene names: 116690367

Gene position: 2609294-2607396 (Counterclockwise)

Preceding gene: 116690368

Following gene: 116690366

Centisome position: 74.9

GC content: 63.98

Gene sequence:

>1899_bases
ATGGCACACGAAACGATGAGCTTTCAGGCAGAGGTCAAGCAACTCCTCCACCTGATGATCCATTCGCTCTACAGCAACAA
GGAAATCTTCCTGCGCGAACTGGTGTCGAATGCGTCCGACGCGGCCGACAAGCTGCGTTTCGAAGGGCTCGCGGACAACG
CGCTGTACGAGAACGATCCGAACCTGCGTATCCGTATCGGCTACGACAAGGCCGCGCGCACGATCACCATCGACGACAAC
GGCATCGGCATGAGCCGCGACGAGGCGATCGCGAACCTCGGCACGATCGCGCGTTCGGGCACCAAGGAATTCTTCACGAA
GCTGTCGGGCGACCAGCAGAAGGACGCGGCGCTGATCGGCCAGTTCGGCGTGGGCTTCTACTCGGGCTTCATCGTTGCCG
ACAAGATCACCGTCGAAACGCGTCGCGCGGGCCTGCCGGCGAACGAAGCCGTGCGCTGGGAAAGCGCGGGCGAGGGCGAT
TTCACGATCGACGCGATCGAGCGCGCGCAACGCGGCACGACGATCACGCTGCACCTGCGCGAAGGCGAGGACGACCTGCT
GTCGTCGCACCGCCTGAAGTCGATCATCCAGAAGTACTCCGACCACATCGCGCTGCCGATCCTGATGCGCAAGGAAGAGT
GGGATCAGGAAAAGGGCGAGATGGTCCTGAAGGACGAGGACGAAACCGTCAACCAGGCGAGCGCGCTGTGGACGCGTTCG
AAGAGCGACGTCACCGACGAGCAGTACACGCAGTTCTACCAGCACATCGCGCACGATCACCAGGACCCGCTCACGTGGAC
GCACAACCGCGTCGAGGGCCGCAGCGAATACACGCAGCTGCTGTTCGTGCCCGCGCACGCGCCGTTCGACCTGTGGAACC
GCGACTATCGCGGCGGCCTGAAGCTGTACGTGAAGCGCGTGTTCATCATGGACGACGCCGAGCAGCTGCTGCCGCAATAC
CTGCGCTTCGTGAAGGGTGTGGTCGATTCGGCCGACCTGCCGCTGAACGTGTCGCGTGAAATCCTGCAGGAAAGCCGCGA
CGTGAAGGCGATCCGCGAAGGCGTGACCAAGCGCGCGCTGTCGATGCTCGAGGAACTCGCGAACGCGGAAGACGATGCCG
GCAAGGAGAAGTACAAGACGTTCTGGGGCGCGTTCGGCCAGGTGCTGAAGGAGGGCCTCGGCGAGGATCACGCGAACCGT
GAGCGCATCGCGAAGCTGCTGCGCTTCGCGTCGACGCATGGCGACACCGACGCGCAGGACGTGTCGCTCGCCGACTACGT
GTCGCGCATGAAGCCCGAGCAGAGCAAGATCTACTACGTGACCGCCGATACGTGGCAGGCCGCGAAGAACAGCCCGCATC
TGGAAGTGTTCCGCAAGAAGGGTGTCGAGGTGCTGCTGCTGACCGACCGCGTCGACGAATGGATGCTGTCGTTCCTGCAT
GAATTCGACGGCAAGCCGCTCGCGAGCGTGGCCCGCGGCGACCTCGATCTCGGCGAGCTGAACGACGAGGAGAAGAAGGC
GCAGGAGCAGGCCGGCGAGGCGATCAAGCCGGTCGTCGAGAAGATGAAGGAAGCGCTCGGCGACAAGGTGAAGGAAGTGC
GCGTCACGTTCCGCCTGACCGATTCGCCGTCGTGCCTCGTCGCGGACGACAACGACATGAGCGGCTACCTGCAGCGGATG
CTGAAGGCAGCCGGCCAGAACGCGCCGGCGATGCAGCCGATCCTCGAGATCAATCCCGAGCACGCGCTCGTGAAGCAGCT
GAACGCCGACAGCGCCGATTTCGGCGACTGGTGCCATCTGCTGTTCGATCAGGCGCTGCTGGCCGAAGGCGGCATGCTCG
ACGATCCGGCGAGCTTCGTGAAGCGGACCAACGCGCTGCTGCTGTCGCGCGCCGCGTGA

Upstream 100 bases:

>100_bases
CCCGGTTGTCCCAACCGGGCGTCCTTCACGGGTCCGCCGGCATCGCGCGCCGGGCGCCGGCGTCACCCCTTTTCAGTTCA
AGTAAGAGGAAACAGCATCC

Downstream 100 bases:

>100_bases
ACGCGCGCATGCGATTCGACGGCGCGCAGGCCGGCTGGCGCGAGACGCCGCGGCCTGGCTGCACGCTCGACCAGCGCGAC
TGGCTGACGCGCGGCGGATC

Product: heat shock protein 90

Products: NA

Alternate protein names: Heat shock protein htpG; High temperature protein G

Number of amino acids: Translated: 632; Mature: 631

Protein sequence:

>632_residues
MAHETMSFQAEVKQLLHLMIHSLYSNKEIFLRELVSNASDAADKLRFEGLADNALYENDPNLRIRIGYDKAARTITIDDN
GIGMSRDEAIANLGTIARSGTKEFFTKLSGDQQKDAALIGQFGVGFYSGFIVADKITVETRRAGLPANEAVRWESAGEGD
FTIDAIERAQRGTTITLHLREGEDDLLSSHRLKSIIQKYSDHIALPILMRKEEWDQEKGEMVLKDEDETVNQASALWTRS
KSDVTDEQYTQFYQHIAHDHQDPLTWTHNRVEGRSEYTQLLFVPAHAPFDLWNRDYRGGLKLYVKRVFIMDDAEQLLPQY
LRFVKGVVDSADLPLNVSREILQESRDVKAIREGVTKRALSMLEELANAEDDAGKEKYKTFWGAFGQVLKEGLGEDHANR
ERIAKLLRFASTHGDTDAQDVSLADYVSRMKPEQSKIYYVTADTWQAAKNSPHLEVFRKKGVEVLLLTDRVDEWMLSFLH
EFDGKPLASVARGDLDLGELNDEEKKAQEQAGEAIKPVVEKMKEALGDKVKEVRVTFRLTDSPSCLVADDNDMSGYLQRM
LKAAGQNAPAMQPILEINPEHALVKQLNADSADFGDWCHLLFDQALLAEGGMLDDPASFVKRTNALLLSRAA

Sequences:

>Translated_632_residues
MAHETMSFQAEVKQLLHLMIHSLYSNKEIFLRELVSNASDAADKLRFEGLADNALYENDPNLRIRIGYDKAARTITIDDN
GIGMSRDEAIANLGTIARSGTKEFFTKLSGDQQKDAALIGQFGVGFYSGFIVADKITVETRRAGLPANEAVRWESAGEGD
FTIDAIERAQRGTTITLHLREGEDDLLSSHRLKSIIQKYSDHIALPILMRKEEWDQEKGEMVLKDEDETVNQASALWTRS
KSDVTDEQYTQFYQHIAHDHQDPLTWTHNRVEGRSEYTQLLFVPAHAPFDLWNRDYRGGLKLYVKRVFIMDDAEQLLPQY
LRFVKGVVDSADLPLNVSREILQESRDVKAIREGVTKRALSMLEELANAEDDAGKEKYKTFWGAFGQVLKEGLGEDHANR
ERIAKLLRFASTHGDTDAQDVSLADYVSRMKPEQSKIYYVTADTWQAAKNSPHLEVFRKKGVEVLLLTDRVDEWMLSFLH
EFDGKPLASVARGDLDLGELNDEEKKAQEQAGEAIKPVVEKMKEALGDKVKEVRVTFRLTDSPSCLVADDNDMSGYLQRM
LKAAGQNAPAMQPILEINPEHALVKQLNADSADFGDWCHLLFDQALLAEGGMLDDPASFVKRTNALLLSRAA
>Mature_631_residues
AHETMSFQAEVKQLLHLMIHSLYSNKEIFLRELVSNASDAADKLRFEGLADNALYENDPNLRIRIGYDKAARTITIDDNG
IGMSRDEAIANLGTIARSGTKEFFTKLSGDQQKDAALIGQFGVGFYSGFIVADKITVETRRAGLPANEAVRWESAGEGDF
TIDAIERAQRGTTITLHLREGEDDLLSSHRLKSIIQKYSDHIALPILMRKEEWDQEKGEMVLKDEDETVNQASALWTRSK
SDVTDEQYTQFYQHIAHDHQDPLTWTHNRVEGRSEYTQLLFVPAHAPFDLWNRDYRGGLKLYVKRVFIMDDAEQLLPQYL
RFVKGVVDSADLPLNVSREILQESRDVKAIREGVTKRALSMLEELANAEDDAGKEKYKTFWGAFGQVLKEGLGEDHANRE
RIAKLLRFASTHGDTDAQDVSLADYVSRMKPEQSKIYYVTADTWQAAKNSPHLEVFRKKGVEVLLLTDRVDEWMLSFLHE
FDGKPLASVARGDLDLGELNDEEKKAQEQAGEAIKPVVEKMKEALGDKVKEVRVTFRLTDSPSCLVADDNDMSGYLQRML
KAAGQNAPAMQPILEINPEHALVKQLNADSADFGDWCHLLFDQALLAEGGMLDDPASFVKRTNALLLSRAA

Specific function: Molecular chaperone. Has ATPase activity

COG id: COG0326

COG function: function code O; Molecular chaperone, HSP90 family

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the heat shock protein 90 family

Homologues:

Organism=Homo sapiens, GI20149594, Length=685, Percent_Identity=39.5620437956204, Blast_Score=439, Evalue=1e-123,
Organism=Homo sapiens, GI4507677, Length=688, Percent_Identity=37.2093023255814, Blast_Score=424, Evalue=1e-118,
Organism=Homo sapiens, GI155722983, Length=637, Percent_Identity=35.4788069073783, Blast_Score=375, Evalue=1e-104,
Organism=Homo sapiens, GI154146191, Length=414, Percent_Identity=40.5797101449275, Blast_Score=287, Evalue=2e-77,
Organism=Homo sapiens, GI153792590, Length=414, Percent_Identity=40.5797101449275, Blast_Score=285, Evalue=1e-76,
Organism=Escherichia coli, GI1786679, Length=630, Percent_Identity=60.4761904761905, Blast_Score=787, Evalue=0.0,
Organism=Caenorhabditis elegans, GI17559162, Length=677, Percent_Identity=38.5524372230428, Blast_Score=457, Evalue=1e-129,
Organism=Caenorhabditis elegans, GI17542208, Length=688, Percent_Identity=37.0639534883721, Blast_Score=396, Evalue=1e-110,
Organism=Caenorhabditis elegans, GI115535205, Length=644, Percent_Identity=32.4534161490683, Blast_Score=308, Evalue=8e-84,
Organism=Caenorhabditis elegans, GI115535167, Length=438, Percent_Identity=35.1598173515982, Blast_Score=245, Evalue=5e-65,
Organism=Saccharomyces cerevisiae, GI6325016, Length=686, Percent_Identity=39.067055393586, Blast_Score=469, Evalue=1e-133,
Organism=Saccharomyces cerevisiae, GI6323840, Length=682, Percent_Identity=39.1495601173021, Blast_Score=468, Evalue=1e-132,
Organism=Drosophila melanogaster, GI17647529, Length=685, Percent_Identity=39.8540145985401, Blast_Score=467, Evalue=1e-131,
Organism=Drosophila melanogaster, GI21357739, Length=677, Percent_Identity=37.5184638109306, Blast_Score=402, Evalue=1e-112,
Organism=Drosophila melanogaster, GI24586016, Length=650, Percent_Identity=35.3846153846154, Blast_Score=362, Evalue=1e-100,

Paralogues:

None

Copy number: 640 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 2419 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): HTPG_BURCA (Q1BUR7)

Other databases:

- EMBL:   CP000378
- RefSeq:   YP_621611.1
- ProteinModelPortal:   Q1BUR7
- SMR:   Q1BUR7
- STRING:   Q1BUR7
- GeneID:   4092933
- GenomeReviews:   CP000378_GR
- KEGG:   bcn:Bcen_1735
- eggNOG:   COG0326
- HOGENOM:   HBG631012
- OMA:   AIYYITA
- ProtClustDB:   PRK05218
- BioCyc:   BCEN331271:BCEN_1735-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00505
- InterPro:   IPR003594
- InterPro:   IPR019805
- InterPro:   IPR001404
- InterPro:   IPR020575
- InterPro:   IPR020568
- Gene3D:   G3DSA:3.30.565.10
- PANTHER:   PTHR11528
- PIRSF:   PIRSF002583
- PRINTS:   PR00775
- SMART:   SM00387

Pfam domain/function: PF02518 HATPase_c; PF00183 HSP90; SSF55874 ATP_bd_ATPase; SSF54211 Ribosomal_S5_D2-typ_fold

EC number: NA

Molecular weight: Translated: 71183; Mature: 71052

Theoretical pI: Translated: 4.92; Mature: 4.92

Prosite motif: PS00298 HSP90

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAHETMSFQAEVKQLLHLMIHSLYSNKEIFLRELVSNASDAADKLRFEGLADNALYENDP
CCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCHHHHHHHHHCCCCCCCCCCCCC
NLRIRIGYDKAARTITIDDNGIGMSRDEAIANLGTIARSGTKEFFTKLSGDQQKDAALIG
CEEEEEECCCCCCEEEECCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHCCCCHHHHHHHH
QFGVGFYSGFIVADKITVETRRAGLPANEAVRWESAGEGDFTIDAIERAQRGTTITLHLR
HHHHHHHHCEEEEEEEEEEHHHCCCCCCCCEECCCCCCCCEEHHHHHHHHCCCEEEEEEE
EGEDDLLSSHRLKSIIQKYSDHIALPILMRKEEWDQEKGEMVLKDEDETVNQASALWTRS
CCCHHHHHHHHHHHHHHHHHCCEEEHHEECCHHHCHHHCCEEEECCCHHHHHHHHHHHCC
KSDVTDEQYTQFYQHIAHDHQDPLTWTHNRVEGRSEYTQLLFVPAHAPFDLWNRDYRGGL
CCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEEEEECCCCHHHCCCCCCCCH
KLYVKRVFIMDDAEQLLPQYLRFVKGVVDSADLPLNVSREILQESRDVKAIREGVTKRAL
HHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
SMLEELANAEDDAGKEKYKTFWGAFGQVLKEGLGEDHANRERIAKLLRFASTHGDTDAQD
HHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCCHH
VSLADYVSRMKPEQSKIYYVTADTWQAAKNSPHLEVFRKKGVEVLLLTDRVDEWMLSFLH
HHHHHHHHHCCCCCCEEEEEECCCHHHCCCCCHHHHHHHCCCEEEEEECHHHHHHHHHHH
EFDGKPLASVARGDLDLGELNDEEKKAQEQAGEAIKPVVEKMKEALGDKVKEVRVTFRLT
HCCCCCHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCHHHHEEEEEEEEE
DSPSCLVADDNDMSGYLQRMLKAAGQNAPAMQPILEINPEHALVKQLNADSADFGDWCHL
CCCCEEEECCCCHHHHHHHHHHHCCCCCCCCCHHHHCCCHHHHHHHHCCCCCCHHHHHHH
LFDQALLAEGGMLDDPASFVKRTNALLLSRAA
HHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
AHETMSFQAEVKQLLHLMIHSLYSNKEIFLRELVSNASDAADKLRFEGLADNALYENDP
CCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCHHHHHHHHHCCCCCCCCCCCCC
NLRIRIGYDKAARTITIDDNGIGMSRDEAIANLGTIARSGTKEFFTKLSGDQQKDAALIG
CEEEEEECCCCCCEEEECCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHCCCCHHHHHHHH
QFGVGFYSGFIVADKITVETRRAGLPANEAVRWESAGEGDFTIDAIERAQRGTTITLHLR
HHHHHHHHCEEEEEEEEEEHHHCCCCCCCCEECCCCCCCCEEHHHHHHHHCCCEEEEEEE
EGEDDLLSSHRLKSIIQKYSDHIALPILMRKEEWDQEKGEMVLKDEDETVNQASALWTRS
CCCHHHHHHHHHHHHHHHHHCCEEEHHEECCHHHCHHHCCEEEECCCHHHHHHHHHHHCC
KSDVTDEQYTQFYQHIAHDHQDPLTWTHNRVEGRSEYTQLLFVPAHAPFDLWNRDYRGGL
CCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEEEEECCCCHHHCCCCCCCCH
KLYVKRVFIMDDAEQLLPQYLRFVKGVVDSADLPLNVSREILQESRDVKAIREGVTKRAL
HHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
SMLEELANAEDDAGKEKYKTFWGAFGQVLKEGLGEDHANRERIAKLLRFASTHGDTDAQD
HHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCCHH
VSLADYVSRMKPEQSKIYYVTADTWQAAKNSPHLEVFRKKGVEVLLLTDRVDEWMLSFLH
HHHHHHHHHCCCCCCEEEEEECCCHHHCCCCCHHHHHHHCCCEEEEEECHHHHHHHHHHH
EFDGKPLASVARGDLDLGELNDEEKKAQEQAGEAIKPVVEKMKEALGDKVKEVRVTFRLT
HCCCCCHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCHHHHEEEEEEEEE
DSPSCLVADDNDMSGYLQRMLKAAGQNAPAMQPILEINPEHALVKQLNADSADFGDWCHL
CCCCEEEECCCCHHHHHHHHHHHCCCCCCCCCHHHHCCCHHHHHHHHCCCCCCHHHHHHH
LFDQALLAEGGMLDDPASFVKRTNALLLSRAA
HHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA