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The map label for this gene is ubiC

Identifier: 116690366

GI number: 116690366

Start: 2606791

End: 2607387

Strand: Reverse

Name: ubiC

Synonym: Bcen2424_2346

Alternate gene names: 116690366

Gene position: 2607387-2606791 (Counterclockwise)

Preceding gene: 116690367

Following gene: 116690365

Centisome position: 74.84

GC content: 74.71

Gene sequence:

>597_bases
ATGCGATTCGACGGCGCGCAGGCCGGCTGGCGCGAGACGCCGCGGCCTGGCTGCACGCTCGACCAGCGCGACTGGCTGAC
GCGCGGCGGATCGCTGACCGCGCACCTCGCGCGGCTCGGCCGCGTGAACGTGCGGGTGACGCGCGAGGCCGTCGACCGCC
CGTGGTTCGACGAGCCGGACGCGCTCGCCAGTTCGCCGCGCGCGCCGATGTGGGTGCGCGAGGTGATCCTGTCGGTCGAC
GGCATGCCGTACGTCGCCGCGCACAGCATCGCGCCGCTCGCGGCCAGCAAGGGCGTGTGGCAGGCGATGCGGCGGCTGCG
CACGCGACCGCTCGCGGAGCTGCTGTACAGCGATCCGCAGGTCGAGCGCTCGGCGCTCGTGAGCCGGCGCGTGATCGCCG
GCCATCCGCTGTATGCGCTCGCGAGCCATGCATTGCTGGGCGCGCGGGCGCCGCATGCGTTCGTCGCGCGGCGCTCGGTG
TTCCAGCGTCACGGCAAGCCGCTGATGGTCACCGAGTGCATGCTGCCGGCGCTGTGGCGCCACCTCGATGCGCACGGCGA
CGGGCCGCGGTCCGTCGGGTCGCACGGAGGCGCGTGA

Upstream 100 bases:

>100_bases
ATCAGGCGCTGCTGGCCGAAGGCGGCATGCTCGACGATCCGGCGAGCTTCGTGAAGCGGACCAACGCGCTGCTGCTGTCG
CGCGCCGCGTGAACGCGCGC

Downstream 100 bases:

>100_bases
TGCTGCAAGGTTTTCCGCCGGTCGTCGCGCCGAATACGCACACGATGATCCTCGGCAGCTTTCCGGGCGAGGCGTCGCTC
GACGCCGCGCAGTACTACGC

Product: chorismate lyase

Products: NA

Alternate protein names: CL; CPL

Number of amino acids: Translated: 198; Mature: 198

Protein sequence:

>198_residues
MRFDGAQAGWRETPRPGCTLDQRDWLTRGGSLTAHLARLGRVNVRVTREAVDRPWFDEPDALASSPRAPMWVREVILSVD
GMPYVAAHSIAPLAASKGVWQAMRRLRTRPLAELLYSDPQVERSALVSRRVIAGHPLYALASHALLGARAPHAFVARRSV
FQRHGKPLMVTECMLPALWRHLDAHGDGPRSVGSHGGA

Sequences:

>Translated_198_residues
MRFDGAQAGWRETPRPGCTLDQRDWLTRGGSLTAHLARLGRVNVRVTREAVDRPWFDEPDALASSPRAPMWVREVILSVD
GMPYVAAHSIAPLAASKGVWQAMRRLRTRPLAELLYSDPQVERSALVSRRVIAGHPLYALASHALLGARAPHAFVARRSV
FQRHGKPLMVTECMLPALWRHLDAHGDGPRSVGSHGGA
>Mature_198_residues
MRFDGAQAGWRETPRPGCTLDQRDWLTRGGSLTAHLARLGRVNVRVTREAVDRPWFDEPDALASSPRAPMWVREVILSVD
GMPYVAAHSIAPLAASKGVWQAMRRLRTRPLAELLYSDPQVERSALVSRRVIAGHPLYALASHALLGARAPHAFVARRSV
FQRHGKPLMVTECMLPALWRHLDAHGDGPRSVGSHGGA

Specific function: Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4- hydroxybenzoate (4HB) for the ubiquinone pathway

COG id: COG3161

COG function: function code H; 4-hydroxybenzoate synthetase (chorismate lyase)

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ubiC family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): UBIC_BURCA (Q1BUR8)

Other databases:

- EMBL:   CP000378
- RefSeq:   YP_621610.1
- ProteinModelPortal:   Q1BUR8
- SMR:   Q1BUR8
- STRING:   Q1BUR8
- GeneID:   4092932
- GenomeReviews:   CP000378_GR
- KEGG:   bcn:Bcen_1734
- eggNOG:   COG3161
- HOGENOM:   HBG644467
- OMA:   GTPYVAA
- ProtClustDB:   CLSK920196
- BioCyc:   BCEN331271:BCEN_1734-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_01632
- InterPro:   IPR007440

Pfam domain/function: PF04345 Chor_lyase

EC number: =4.1.3.40

Molecular weight: Translated: 21842; Mature: 21842

Theoretical pI: Translated: 11.53; Mature: 11.53

Prosite motif: NA

Important sites: BINDING 73-73 BINDING 111-111

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRFDGAQAGWRETPRPGCTLDQRDWLTRGGSLTAHLARLGRVNVRVTREAVDRPWFDEPD
CCCCCCCCCCCCCCCCCCCCCHHHHHHCCCCHHHHHHHHCCCCEEEEHHHHCCCCCCCCH
ALASSPRAPMWVREVILSVDGMPYVAAHSIAPLAASKGVWQAMRRLRTRPLAELLYSDPQ
HHHCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCC
VERSALVSRRVIAGHPLYALASHALLGARAPHAFVARRSVFQRHGKPLMVTECMLPALWR
HHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCEEHHHHHHHHHHH
HLDAHGDGPRSVGSHGGA
HHHCCCCCCCCCCCCCCC
>Mature Secondary Structure
MRFDGAQAGWRETPRPGCTLDQRDWLTRGGSLTAHLARLGRVNVRVTREAVDRPWFDEPD
CCCCCCCCCCCCCCCCCCCCCHHHHHHCCCCHHHHHHHHCCCCEEEEHHHHCCCCCCCCH
ALASSPRAPMWVREVILSVDGMPYVAAHSIAPLAASKGVWQAMRRLRTRPLAELLYSDPQ
HHHCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCC
VERSALVSRRVIAGHPLYALASHALLGARAPHAFVARRSVFQRHGKPLMVTECMLPALWR
HHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCEEHHHHHHHHHHH
HLDAHGDGPRSVGSHGGA
HHHCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA