Click here to switch to the map view.

The map label for this gene is ybdL [H]

Identifier: 116690246

GI number: 116690246

Start: 2480567

End: 2481739

Strand: Direct

Name: ybdL [H]

Synonym: Bcen2424_2225

Alternate gene names: 116690246

Gene position: 2480567-2481739 (Clockwise)

Preceding gene: 116690245

Following gene: 116690248

Centisome position: 71.2

GC content: 66.5

Gene sequence:

>1173_bases
ATGAACGCTCCTTCAGATATGCCAACGACTCCCGTTTTCCCCTCGCGCCTGCCGAACGTCGGCACGACGATCTTCACGAT
CATGAGCGCGCTTGCCGCCGAAAAAGGCGCGGTGAACCTCGGCCAGGGCTTTCCGGATTTCGATTGCGATCCGCGCATCG
TCGATGCGGTCGCCGCCGCGATGCGCAACGGGCACAACCAGTACCCGCCGATGGCCGGCGTCGCGCCGCTGCGCGACGCG
ATCGCCGACAAGATCGCGCAGGTGTACGGCCGGCGCTACGATCCGGGCACCGAAATCACCGTGACGGCCGGCGCGACCCA
GGCGCTGCTGACGGCGATCCTGTGCGCGGTGCATCCGGGCGACGAAGTGATCGTGGTCGAGCCGACCTACGACAGCTACC
TGCCGTCGATCGAACTCGCCGGCGGCAAGCCCGTGTTCGTCACGCTGGAGGCGCCCGACTACGCGATCCCGTTCGACCGT
CTCGCGGCCGCGATCACGCCGAAAACGCGAATGATCCTGATCAACACGCCGCACAACCCGACGGGCACCGTGTGGCGCGA
GGCGGACATGCGCAAGCTCGAGGACATCGTGCGCGGCACCAACGTGCTGATCCTGTCCGACGAGGTCTACGAGCACATGG
TCTACGACGGCGCGCGCCACGAGAGCGTCGCGCGCTATCCGGAACTCGCCGCGCGCAGCTTCATCGTGTCGAGCTTCGGC
AAGACCTATCACGTGACGGGCTGGAAGGTCGGTTACGTCGCGGCGCCGGCGGCGCTGACCGCGGAGTTCCGCAAGGTCCA
CCAGTTCAACGTGTTCACGGTGAACACGCCGATGCAGATCGGGCTCGCCGACTACCTGCGGGACCCGGCGCCGTACCTGT
CGCTCGCGGGCTTCTATCAGCGCAAGCGCGACTTCTTCCGGGCCGGTCTCGAGCGCACGCGCTTCAAGCTGCTGCCGTGC
ACGGGCACGTACTTCCAGTGCGTCGATTACTCGGCGATCAGCGACCTGCCCGAAGCGGAATTCTCGAAGTGGCTCACGTC
GGAGATCGGCGTGGCCGCCATTCCGGTGTCGGCGTTCTATCACGAGCCGCACGAATCGGGCGTCGTGCGCTTCTGCTTCG
CGAAGCAGGAAAGCACGCTCGCGTCCGCGCTCGAACGGCTGGCCCGCCTGTAA

Upstream 100 bases:

>100_bases
CGCACAACCCGCGCCGTTTGCCGAAGCCTGCGCCCTCGACGCCGCGCCGCCCGCCACGGCGACGCCGGCCTGACGCCCCA
ATCCGAATTCGACCGTATCG

Downstream 100 bases:

>100_bases
GACCGCACGGGCGGCCGCACGCCGCCCTTCGGGAACCGCGGTTACGAACGCGCGACGTTCGCCGCTTCGACATACGCCTT
GCGCTCGGCGGCCACGCGCT

Product: putative aminotransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 390; Mature: 390

Protein sequence:

>390_residues
MNAPSDMPTTPVFPSRLPNVGTTIFTIMSALAAEKGAVNLGQGFPDFDCDPRIVDAVAAAMRNGHNQYPPMAGVAPLRDA
IADKIAQVYGRRYDPGTEITVTAGATQALLTAILCAVHPGDEVIVVEPTYDSYLPSIELAGGKPVFVTLEAPDYAIPFDR
LAAAITPKTRMILINTPHNPTGTVWREADMRKLEDIVRGTNVLILSDEVYEHMVYDGARHESVARYPELAARSFIVSSFG
KTYHVTGWKVGYVAAPAALTAEFRKVHQFNVFTVNTPMQIGLADYLRDPAPYLSLAGFYQRKRDFFRAGLERTRFKLLPC
TGTYFQCVDYSAISDLPEAEFSKWLTSEIGVAAIPVSAFYHEPHESGVVRFCFAKQESTLASALERLARL

Sequences:

>Translated_390_residues
MNAPSDMPTTPVFPSRLPNVGTTIFTIMSALAAEKGAVNLGQGFPDFDCDPRIVDAVAAAMRNGHNQYPPMAGVAPLRDA
IADKIAQVYGRRYDPGTEITVTAGATQALLTAILCAVHPGDEVIVVEPTYDSYLPSIELAGGKPVFVTLEAPDYAIPFDR
LAAAITPKTRMILINTPHNPTGTVWREADMRKLEDIVRGTNVLILSDEVYEHMVYDGARHESVARYPELAARSFIVSSFG
KTYHVTGWKVGYVAAPAALTAEFRKVHQFNVFTVNTPMQIGLADYLRDPAPYLSLAGFYQRKRDFFRAGLERTRFKLLPC
TGTYFQCVDYSAISDLPEAEFSKWLTSEIGVAAIPVSAFYHEPHESGVVRFCFAKQESTLASALERLARL
>Mature_390_residues
MNAPSDMPTTPVFPSRLPNVGTTIFTIMSALAAEKGAVNLGQGFPDFDCDPRIVDAVAAAMRNGHNQYPPMAGVAPLRDA
IADKIAQVYGRRYDPGTEITVTAGATQALLTAILCAVHPGDEVIVVEPTYDSYLPSIELAGGKPVFVTLEAPDYAIPFDR
LAAAITPKTRMILINTPHNPTGTVWREADMRKLEDIVRGTNVLILSDEVYEHMVYDGARHESVARYPELAARSFIVSSFG
KTYHVTGWKVGYVAAPAALTAEFRKVHQFNVFTVNTPMQIGLADYLRDPAPYLSLAGFYQRKRDFFRAGLERTRFKLLPC
TGTYFQCVDYSAISDLPEAEFSKWLTSEIGVAAIPVSAFYHEPHESGVVRFCFAKQESTLASALERLARL

Specific function: Shows aminotransferase activity with methionine and histidine as substrates, and to a lesser extent also with phenylalanine [H]

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI95147551, Length=409, Percent_Identity=34.718826405868, Blast_Score=232, Evalue=4e-61,
Organism=Homo sapiens, GI169881279, Length=409, Percent_Identity=34.718826405868, Blast_Score=232, Evalue=4e-61,
Organism=Homo sapiens, GI56713254, Length=401, Percent_Identity=33.9152119700748, Blast_Score=220, Evalue=2e-57,
Organism=Homo sapiens, GI56713256, Length=401, Percent_Identity=33.9152119700748, Blast_Score=220, Evalue=2e-57,
Organism=Homo sapiens, GI169881281, Length=408, Percent_Identity=30.3921568627451, Blast_Score=184, Evalue=1e-46,
Organism=Homo sapiens, GI4507369, Length=216, Percent_Identity=26.8518518518519, Blast_Score=80, Evalue=2e-15,
Organism=Escherichia coli, GI1786816, Length=386, Percent_Identity=50.7772020725389, Blast_Score=400, Evalue=1e-113,
Organism=Escherichia coli, GI1788722, Length=379, Percent_Identity=25.8575197889182, Blast_Score=115, Evalue=6e-27,
Organism=Escherichia coli, GI1788627, Length=188, Percent_Identity=31.9148936170213, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI1787710, Length=297, Percent_Identity=28.6195286195286, Blast_Score=79, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI71994472, Length=404, Percent_Identity=35.6435643564356, Blast_Score=232, Evalue=3e-61,
Organism=Caenorhabditis elegans, GI71994476, Length=403, Percent_Identity=35.2357320099256, Blast_Score=231, Evalue=4e-61,
Organism=Caenorhabditis elegans, GI17567369, Length=406, Percent_Identity=31.5270935960591, Blast_Score=192, Evalue=3e-49,
Organism=Caenorhabditis elegans, GI17567663, Length=203, Percent_Identity=25.1231527093596, Blast_Score=71, Evalue=8e-13,
Organism=Saccharomyces cerevisiae, GI6322401, Length=396, Percent_Identity=33.0808080808081, Blast_Score=194, Evalue=2e-50,
Organism=Drosophila melanogaster, GI28573069, Length=411, Percent_Identity=35.5231143552311, Blast_Score=243, Evalue=2e-64,
Organism=Drosophila melanogaster, GI24646114, Length=411, Percent_Identity=35.5231143552311, Blast_Score=243, Evalue=2e-64,
Organism=Drosophila melanogaster, GI28573067, Length=411, Percent_Identity=35.5231143552311, Blast_Score=243, Evalue=2e-64,
Organism=Drosophila melanogaster, GI28573065, Length=411, Percent_Identity=35.5231143552311, Blast_Score=243, Evalue=2e-64,
Organism=Drosophila melanogaster, GI18859735, Length=207, Percent_Identity=28.5024154589372, Blast_Score=74, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: 2.6.1.- [C]

Molecular weight: Translated: 42847; Mature: 42847

Theoretical pI: Translated: 6.24; Mature: 6.24

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNAPSDMPTTPVFPSRLPNVGTTIFTIMSALAAEKGAVNLGQGFPDFDCDPRIVDAVAAA
CCCCCCCCCCCCCHHHCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHH
MRNGHNQYPPMAGVAPLRDAIADKIAQVYGRRYDPGTEITVTAGATQALLTAILCAVHPG
HHCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCHHHHHHHHHHHCCCC
DEVIVVEPTYDSYLPSIELAGGKPVFVTLEAPDYAIPFDRLAAAITPKTRMILINTPHNP
CCEEEECCCHHHHCCCEEECCCCEEEEEECCCCCCCCHHHHHHHCCCCEEEEEEECCCCC
TGTVWREADMRKLEDIVRGTNVLILSDEVYEHMVYDGARHESVARYPELAARSFIVSSFG
CCCEECHHHHHHHHHHHCCCCEEEECHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCC
KTYHVTGWKVGYVAAPAALTAEFRKVHQFNVFTVNTPMQIGLADYLRDPAPYLSLAGFYQ
CEEEECCEEEEHEECCHHHHHHHHHHHEEEEEEECCCHHHCHHHHHCCCCCHHHHHHHHH
RKRDFFRAGLERTRFKLLPCTGTYFQCVDYSAISDLPEAEFSKWLTSEIGVAAIPVSAFY
HHHHHHHHHHHHCCEEEEECCCCHHHHCCHHHHHCCCHHHHHHHHHHCCCEEEEEHHHHH
HEPHESGVVRFCFAKQESTLASALERLARL
CCCCCCCEEEEEECCCHHHHHHHHHHHHCC
>Mature Secondary Structure
MNAPSDMPTTPVFPSRLPNVGTTIFTIMSALAAEKGAVNLGQGFPDFDCDPRIVDAVAAA
CCCCCCCCCCCCCHHHCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHH
MRNGHNQYPPMAGVAPLRDAIADKIAQVYGRRYDPGTEITVTAGATQALLTAILCAVHPG
HHCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCHHHHHHHHHHHCCCC
DEVIVVEPTYDSYLPSIELAGGKPVFVTLEAPDYAIPFDRLAAAITPKTRMILINTPHNP
CCEEEECCCHHHHCCCEEECCCCEEEEEECCCCCCCCHHHHHHHCCCCEEEEEEECCCCC
TGTVWREADMRKLEDIVRGTNVLILSDEVYEHMVYDGARHESVARYPELAARSFIVSSFG
CCCEECHHHHHHHHHHHCCCCEEEECHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCC
KTYHVTGWKVGYVAAPAALTAEFRKVHQFNVFTVNTPMQIGLADYLRDPAPYLSLAGFYQ
CEEEECCEEEEHEECCHHHHHHHHHHHEEEEEEECCCHHHCHHHHHCCCCCHHHHHHHHH
RKRDFFRAGLERTRFKLLPCTGTYFQCVDYSAISDLPEAEFSKWLTSEIGVAAIPVSAFY
HHHHHHHHHHHHCCEEEEECCCCHHHHCCHHHHHCCCHHHHHHHHHHCCCEEEEEHHHHH
HEPHESGVVRFCFAKQESTLASALERLARL
CCCCCCCEEEEEECCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: Pyridoxal Phosphate. [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8905232; 9278503 [H]