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The map label for this gene is argM [C]

Identifier: 116690183

GI number: 116690183

Start: 2408174

End: 2409568

Strand: Reverse

Name: argM [C]

Synonym: Bcen2424_2162

Alternate gene names: 116690183

Gene position: 2409568-2408174 (Counterclockwise)

Preceding gene: 116690184

Following gene: 116690181

Centisome position: 69.16

GC content: 66.02

Gene sequence:

>1395_bases
ATGACCGATCGAAACGAAGCTTTTCCGCCGCGCTCGACCGCCGATTTTCGCGCGCTCGATGCCGCCCACCACATCCACCC
GTTCTCCGACATGGGCGCGCTCAACCGCGCCGGCAGCCGCGTGATCGTGAAGGCCGACGGCGTCTATCTGTGGGACTCGG
ACGGCAACAAGGTGATCGACGGGATGGCCGGCCTCTGGTGCGTGAACGTCGGCTACGGCCGCAAGGAGCTCGCCGACGCC
GCGTATCACCAGATCCAGGAACTGCCGTTCTACAACACGTTTTTCAAGACCACGCATCCGCCGGTGATCGAGCTTTCCGC
GATGCTCGCGGAAGTGACGCCCACTGGCTTCAACCACTTCTTCTATTGCAACAGCGGCTCGGAAGGCAACGACACCGTGC
TGCGTCTCGTGCATCAGTACTGGCGCGTGCAGGGCAAGCCGCAGAAGAAGTATGTGATCTCGCGCAAGAACGGCTACCAC
GGCTCGACGATCGCGGGGGGCACGCTCGGCGGGATGGGCTACATGCACGAGCAGATGCCGTCAAAGGTCGAGCACATCGT
GCACATCGATCAGCCGTATTTCTTCGGCGAAGCGCAAGCAGGCGAGACGCCCGAAGCATTCGGCCTCGCACGCGCGCAGC
AGCTCGAAGCGAAGATCCTCGAACTCGGCGCGGAGAACGTCGCGGCGTTCATCGGCGAGCCGTTCCAGGGCGCGGGCGGC
GTGATCTTCCCGCCGTCGACGTACTGGCCGGAAATCCAGCGGATCTGCCGCAAGTACGACGTCCTGCTGGTCGCCGACGA
AGTGATCGGCGGCTTCGGGCGCACCGGCGAATGGTTCGCGCACCAGCACTTCGGCTTCGAGCCGGACCTGATCACGATGG
CGAAGGGCCTCACGTCGGGCTACGTGCCGATGGGCGCGGTCGGCATTCACGAGCGCGTCGCGCGCCCGATCATCGACAAC
GGCGAATTCAATCACGGCCTCACGTACTCGGGGCACCCGGTGGCGGCGGCCGTCGCGGTCGCGAACCTTAAGCTGCTGCG
CGACGAGGGGATCGTCGAGCGGGTAAAGACCGATATCGGGCCGTATTTCCAGCGTCGGCTGCGTGACGTGCTGGGCGACC
ATCCGATCGTCGGGGAGATTGCGGGAGCGGGGCTGGTCGCCGGCGTTCAACTGGCGCGCGACCGGGGGCGGCGCGAGCGC
TTCGGCGCGGACGTCGATGTCGGCACGATCTGCCGCGACTTCTGCTTCAACGGCAACCTGATCATGCGCGCGACCGGCGA
CCGGATGCTGCTGTCGCCGCCGCTCGTGATTCGCGAGGCGGAAGTCGACGAGATCGTCGACAAGGCGAAGCGCGCGTTCG
ACGCGACGGCGGAGCGGGTGGGGCGCGCACGGTAA

Upstream 100 bases:

>100_bases
GAAACCGAATACGAAGCGTTCTTCCGCGTGATCAGCTCGTGGGAACGCAGGCACCTGCTGCTGCACGTGTAAGCGTGCGG
CGCTGTTTGACGGAGAAAAC

Downstream 100 bases:

>100_bases
GCCGGTAGCTGCGTGCGGACGCGAGCGTCGAATGACGCGGCGCCCGCGTCGCGCAGGATACGCGCGACGCCAAAACGAAA
AGGGCCTGCGTCGTGAGACG

Product: putative aminotransferase

Products: L-glutamate; N2-succinylglutamic-semialdehyde [C]

Alternate protein names: NA

Number of amino acids: Translated: 464; Mature: 463

Protein sequence:

>464_residues
MTDRNEAFPPRSTADFRALDAAHHIHPFSDMGALNRAGSRVIVKADGVYLWDSDGNKVIDGMAGLWCVNVGYGRKELADA
AYHQIQELPFYNTFFKTTHPPVIELSAMLAEVTPTGFNHFFYCNSGSEGNDTVLRLVHQYWRVQGKPQKKYVISRKNGYH
GSTIAGGTLGGMGYMHEQMPSKVEHIVHIDQPYFFGEAQAGETPEAFGLARAQQLEAKILELGAENVAAFIGEPFQGAGG
VIFPPSTYWPEIQRICRKYDVLLVADEVIGGFGRTGEWFAHQHFGFEPDLITMAKGLTSGYVPMGAVGIHERVARPIIDN
GEFNHGLTYSGHPVAAAVAVANLKLLRDEGIVERVKTDIGPYFQRRLRDVLGDHPIVGEIAGAGLVAGVQLARDRGRRER
FGADVDVGTICRDFCFNGNLIMRATGDRMLLSPPLVIREAEVDEIVDKAKRAFDATAERVGRAR

Sequences:

>Translated_464_residues
MTDRNEAFPPRSTADFRALDAAHHIHPFSDMGALNRAGSRVIVKADGVYLWDSDGNKVIDGMAGLWCVNVGYGRKELADA
AYHQIQELPFYNTFFKTTHPPVIELSAMLAEVTPTGFNHFFYCNSGSEGNDTVLRLVHQYWRVQGKPQKKYVISRKNGYH
GSTIAGGTLGGMGYMHEQMPSKVEHIVHIDQPYFFGEAQAGETPEAFGLARAQQLEAKILELGAENVAAFIGEPFQGAGG
VIFPPSTYWPEIQRICRKYDVLLVADEVIGGFGRTGEWFAHQHFGFEPDLITMAKGLTSGYVPMGAVGIHERVARPIIDN
GEFNHGLTYSGHPVAAAVAVANLKLLRDEGIVERVKTDIGPYFQRRLRDVLGDHPIVGEIAGAGLVAGVQLARDRGRRER
FGADVDVGTICRDFCFNGNLIMRATGDRMLLSPPLVIREAEVDEIVDKAKRAFDATAERVGRAR
>Mature_463_residues
TDRNEAFPPRSTADFRALDAAHHIHPFSDMGALNRAGSRVIVKADGVYLWDSDGNKVIDGMAGLWCVNVGYGRKELADAA
YHQIQELPFYNTFFKTTHPPVIELSAMLAEVTPTGFNHFFYCNSGSEGNDTVLRLVHQYWRVQGKPQKKYVISRKNGYHG
STIAGGTLGGMGYMHEQMPSKVEHIVHIDQPYFFGEAQAGETPEAFGLARAQQLEAKILELGAENVAAFIGEPFQGAGGV
IFPPSTYWPEIQRICRKYDVLLVADEVIGGFGRTGEWFAHQHFGFEPDLITMAKGLTSGYVPMGAVGIHERVARPIIDNG
EFNHGLTYSGHPVAAAVAVANLKLLRDEGIVERVKTDIGPYFQRRLRDVLGDHPIVGEIAGAGLVAGVQLARDRGRRERF
GADVDVGTICRDFCFNGNLIMRATGDRMLLSPPLVIREAEVDEIVDKAKRAFDATAERVGRAR

Specific function: Catalyzes The Transmination Of N(2)-Succinylornithine And Alpha-Ketoglutarate Into N(2)-Succinylglutamate Semialdehyde And Glutamate. Can Also Act As A Acetylornithine Aminotransferase. [C]

COG id: COG0161

COG function: function code H; Adenosylmethionine-8-amino-7-oxononanoate aminotransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI4557809, Length=440, Percent_Identity=27.5, Blast_Score=140, Evalue=3e-33,
Organism=Homo sapiens, GI24119277, Length=362, Percent_Identity=30.1104972375691, Blast_Score=140, Evalue=4e-33,
Organism=Homo sapiens, GI37574042, Length=454, Percent_Identity=27.3127753303965, Blast_Score=139, Evalue=5e-33,
Organism=Homo sapiens, GI226442705, Length=451, Percent_Identity=27.4944567627494, Blast_Score=137, Evalue=2e-32,
Organism=Homo sapiens, GI13994255, Length=434, Percent_Identity=26.036866359447, Blast_Score=134, Evalue=1e-31,
Organism=Homo sapiens, GI226442709, Length=407, Percent_Identity=26.7813267813268, Blast_Score=127, Evalue=2e-29,
Organism=Homo sapiens, GI284507298, Length=231, Percent_Identity=32.4675324675325, Blast_Score=117, Evalue=2e-26,
Organism=Homo sapiens, GI188536080, Length=428, Percent_Identity=22.8971962616822, Blast_Score=80, Evalue=5e-15,
Organism=Homo sapiens, GI38679950, Length=428, Percent_Identity=22.8971962616822, Blast_Score=80, Evalue=5e-15,
Organism=Homo sapiens, GI38679946, Length=428, Percent_Identity=22.8971962616822, Blast_Score=80, Evalue=5e-15,
Organism=Escherichia coli, GI1788044, Length=409, Percent_Identity=28.6063569682152, Blast_Score=160, Evalue=1e-40,
Organism=Escherichia coli, GI1786991, Length=448, Percent_Identity=29.4642857142857, Blast_Score=152, Evalue=4e-38,
Organism=Escherichia coli, GI145693181, Length=410, Percent_Identity=25.8536585365854, Blast_Score=150, Evalue=2e-37,
Organism=Escherichia coli, GI1789759, Length=407, Percent_Identity=27.2727272727273, Blast_Score=147, Evalue=2e-36,
Organism=Escherichia coli, GI1789016, Length=467, Percent_Identity=24.1970021413276, Blast_Score=120, Evalue=2e-28,
Organism=Escherichia coli, GI1787560, Length=360, Percent_Identity=28.6111111111111, Blast_Score=110, Evalue=2e-25,
Organism=Escherichia coli, GI1786349, Length=314, Percent_Identity=24.5222929936306, Blast_Score=79, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI32564660, Length=435, Percent_Identity=30.3448275862069, Blast_Score=151, Evalue=8e-37,
Organism=Caenorhabditis elegans, GI25144271, Length=413, Percent_Identity=27.8450363196126, Blast_Score=150, Evalue=1e-36,
Organism=Caenorhabditis elegans, GI71992977, Length=422, Percent_Identity=27.4881516587678, Blast_Score=148, Evalue=7e-36,
Organism=Caenorhabditis elegans, GI25144274, Length=321, Percent_Identity=29.595015576324, Blast_Score=133, Evalue=2e-31,
Organism=Caenorhabditis elegans, GI17541228, Length=449, Percent_Identity=24.2761692650334, Blast_Score=84, Evalue=1e-16,
Organism=Saccharomyces cerevisiae, GI6323470, Length=455, Percent_Identity=26.3736263736264, Blast_Score=158, Evalue=2e-39,
Organism=Saccharomyces cerevisiae, GI6324432, Length=432, Percent_Identity=25.462962962963, Blast_Score=133, Evalue=7e-32,
Organism=Saccharomyces cerevisiae, GI6324386, Length=420, Percent_Identity=28.5714285714286, Blast_Score=124, Evalue=2e-29,
Organism=Drosophila melanogaster, GI21357415, Length=440, Percent_Identity=27.5, Blast_Score=146, Evalue=2e-35,
Organism=Drosophila melanogaster, GI161085790, Length=444, Percent_Identity=28.6036036036036, Blast_Score=146, Evalue=4e-35,
Organism=Drosophila melanogaster, GI28574759, Length=434, Percent_Identity=28.8018433179723, Blast_Score=145, Evalue=6e-35,
Organism=Drosophila melanogaster, GI21356575, Length=371, Percent_Identity=28.5714285714286, Blast_Score=134, Evalue=2e-31,
Organism=Drosophila melanogaster, GI281366494, Length=451, Percent_Identity=23.2815964523282, Blast_Score=77, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24667139, Length=451, Percent_Identity=23.2815964523282, Blast_Score=77, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24667143, Length=451, Percent_Identity=23.2815964523282, Blast_Score=77, Evalue=3e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005814
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00202 Aminotran_3 [H]

EC number: 2.6.1.- [C]

Molecular weight: Translated: 51071; Mature: 50939

Theoretical pI: Translated: 6.66; Mature: 6.66

Prosite motif: PS00600 AA_TRANSFER_CLASS_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDRNEAFPPRSTADFRALDAAHHIHPFSDMGALNRAGSRVIVKADGVYLWDSDGNKVID
CCCCCCCCCCCCCCCHHHHHHHHHCCCCHHHHHHHCCCCEEEEEECCEEEECCCCCCHHH
GMAGLWCVNVGYGRKELADAAYHQIQELPFYNTFFKTTHPPVIELSAMLAEVTPTGFNHF
CCCCEEEEECCCCHHHHHHHHHHHHHHCCCHHHHHCCCCCCHHHHHHHHHHCCCCCCCEE
FYCNSGSEGNDTVLRLVHQYWRVQGKPQKKYVISRKNGYHGSTIAGGTLGGMGYMHEQMP
EEECCCCCCHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCCCCCCCCCCCCHHHHHHHHH
SKVEHIVHIDQPYFFGEAQAGETPEAFGLARAQQLEAKILELGAENVAAFIGEPFQGAGG
HHHHHHEECCCCEEECCCCCCCCCHHHHHHHHHHHHHHHHHHCHHHHHHHHCCCCCCCCC
VIFPPSTYWPEIQRICRKYDVLLVADEVIGGFGRTGEWFAHQHFGFEPDLITMAKGLTSG
EEECCCCCCHHHHHHHHHHCEEEEEHHHHCCCCCCCHHHHHHCCCCCCCHHHHHHHCCCC
YVPMGAVGIHERVARPIIDNGEFNHGLTYSGHPVAAAVAVANLKLLRDEGIVERVKTDIG
CCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCC
PYFQRRLRDVLGDHPIVGEIAGAGLVAGVQLARDRGRRERFGADVDVGTICRDFCFNGNL
HHHHHHHHHHHCCCCCCHHHHCCHHHHHHHHHHHCCHHHHCCCCCCHHHHHHHHHCCCCE
IMRATGDRMLLSPPLVIREAEVDEIVDKAKRAFDATAERVGRAR
EEEECCCEEEECCCCEEECCHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
TDRNEAFPPRSTADFRALDAAHHIHPFSDMGALNRAGSRVIVKADGVYLWDSDGNKVID
CCCCCCCCCCCCCCHHHHHHHHHCCCCHHHHHHHCCCCEEEEEECCEEEECCCCCCHHH
GMAGLWCVNVGYGRKELADAAYHQIQELPFYNTFFKTTHPPVIELSAMLAEVTPTGFNHF
CCCCEEEEECCCCHHHHHHHHHHHHHHCCCHHHHHCCCCCCHHHHHHHHHHCCCCCCCEE
FYCNSGSEGNDTVLRLVHQYWRVQGKPQKKYVISRKNGYHGSTIAGGTLGGMGYMHEQMP
EEECCCCCCHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCCCCCCCCCCCCHHHHHHHHH
SKVEHIVHIDQPYFFGEAQAGETPEAFGLARAQQLEAKILELGAENVAAFIGEPFQGAGG
HHHHHHEECCCCEEECCCCCCCCCHHHHHHHHHHHHHHHHHHCHHHHHHHHCCCCCCCCC
VIFPPSTYWPEIQRICRKYDVLLVADEVIGGFGRTGEWFAHQHFGFEPDLITMAKGLTSG
EEECCCCCCHHHHHHHHHHCEEEEEHHHHCCCCCCCHHHHHHCCCCCCCHHHHHHHCCCC
YVPMGAVGIHERVARPIIDNGEFNHGLTYSGHPVAAAVAVANLKLLRDEGIVERVKTDIG
CCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCC
PYFQRRLRDVLGDHPIVGEIAGAGLVAGVQLARDRGRRERFGADVDVGTICRDFCFNGNL
HHHHHHHHHHHCCCCCCHHHHCCHHHHHHHHHHHCCHHHHCCCCCCHHHHHHHHHCCCCE
IMRATGDRMLLSPPLVIREAEVDEIVDKAKRAFDATAERVGRAR
EEEECCCEEEECCCCEEECCHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: Pyridoxal Phosphate. [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: N-alpha-acetylornithine; 2-oxoglutarate [C]

Specific reaction: N-alpha-acetylornithine + 2-oxoglutarate = N-acetylglutamate semialdehyde + L-glutamate N2-succinylornithine + 2-oxoglutarate = N2-succinylglutamic-semialdehyde + L-glutamate [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8796346; 9163424 [H]