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The map label for this gene is dinB [H]

Identifier: 116690163

GI number: 116690163

Start: 2380485

End: 2381570

Strand: Reverse

Name: dinB [H]

Synonym: Bcen2424_2142

Alternate gene names: 116690163

Gene position: 2381570-2380485 (Counterclockwise)

Preceding gene: 116690167

Following gene: 116690158

Centisome position: 68.36

GC content: 68.69

Gene sequence:

>1086_bases
ATGCGCAAGATCATTCATTGCGACTGCGACTGCTTCTACGCGTCGGTCGAGATGCGCGACGACCCGTCGCTGCGCAACCG
GCCGCTCGCGGTCGGCGGTCGCCCCGACCAGCGCGGCGTGATCGCGACCTGTAACTACGAGGCGCGGCGCTACGGCGTGC
ATTCGGCGATGTCGTCCGCGCTGGCGATGCGCAAGTGCCCGGACCTGCTGATCCTGCCGTCCGCGATGGACAAGTATCGC
GCGGCGTCGCGGCAGATCATGGCGATCTATCGCGACTACACGCCGGACGTCGAGCCGCTGTCGCTCGACGAGGCGTACCT
CGACGTCAGCGGGTCCGAACGTTGCCAGGGCAGTGCGACGCTGATTGCGCGCGAGATCCGCGAGCGCGTGCGCGATACGG
TCGGCGTGACCGTGTCGGCGGGCGTCGCGCCGAACAAGTTCATCGCGAAGATCGCGTCCGACTGGAACAAGCCCGACGGG
CTGTTCGTCGTGCGGCCGCACGAGATCGACGCGTTCGTCGCGGCGCTGCCGGTGCGCAAGCTGCACGGCGTCGGCAAGGT
GACGGCCACGCGGCTCGACCGGCTCGGCATCCAGACCTGCGCGCAATTGCGCGACTGGCCGCTGATCGACCTGCACCGCG
AGTTCGGCGCGTTCGGGCGGCGGCTGTACGAACTGTCGCGCGGGATCGACGAGCGGCCTGTGCAGGCCGACCAGGAGCGC
AAGTCGGTCAGCGTCGAGACGACCTACGTGACCGACCTGACGACGCTCGAACAATGCGCGGACGAAATCCGTCGCCTCGT
CGTGCAACTCGACGCGCGGATCGATCGCGCGGGCGCCGCGCGGTCGATCCGCAAGCTGTACGTGAAGATCCGCTTCGCCG
ATTTCCAGCGCACGACGGTCGAGTGCGTGGCCGACGCGACGAATGCCGAGACGGCCGTCACGCTGCTCGCGAAGGGGTTG
TTGCGGCGCGCGCAGCCGGTGCGGCTGCTCGGCGTCGGCGTGCGCATCGACGAGGATACGGCCGAACGCCACGGGCAATT
TCTGCTGTTCGACGACGAAGTGGGCGACGACACGCCCGCGCCATGA

Upstream 100 bases:

>100_bases
AACCGGCACTGTGTTTTTGTACAGTATCGGCACCGTGAGCCCGACCACCATCCTGCCTGCCGATCTACCCACGCCACCGC
CCGGCGACGCGCCGCCGCGC

Downstream 100 bases:

>100_bases
AAAAAGGCACCGCCGAAGCGGTGCCTGTCGATGCAGCCTGAACAACTGGAAGGGCCGGGCAGCGCGCTCAGTGCGCGGAC
GCGGCCATCCCGTTGTGGCG

Product: DNA polymerase IV

Products: NA

Alternate protein names: Pol IV [H]

Number of amino acids: Translated: 361; Mature: 361

Protein sequence:

>361_residues
MRKIIHCDCDCFYASVEMRDDPSLRNRPLAVGGRPDQRGVIATCNYEARRYGVHSAMSSALAMRKCPDLLILPSAMDKYR
AASRQIMAIYRDYTPDVEPLSLDEAYLDVSGSERCQGSATLIAREIRERVRDTVGVTVSAGVAPNKFIAKIASDWNKPDG
LFVVRPHEIDAFVAALPVRKLHGVGKVTATRLDRLGIQTCAQLRDWPLIDLHREFGAFGRRLYELSRGIDERPVQADQER
KSVSVETTYVTDLTTLEQCADEIRRLVVQLDARIDRAGAARSIRKLYVKIRFADFQRTTVECVADATNAETAVTLLAKGL
LRRAQPVRLLGVGVRIDEDTAERHGQFLLFDDEVGDDTPAP

Sequences:

>Translated_361_residues
MRKIIHCDCDCFYASVEMRDDPSLRNRPLAVGGRPDQRGVIATCNYEARRYGVHSAMSSALAMRKCPDLLILPSAMDKYR
AASRQIMAIYRDYTPDVEPLSLDEAYLDVSGSERCQGSATLIAREIRERVRDTVGVTVSAGVAPNKFIAKIASDWNKPDG
LFVVRPHEIDAFVAALPVRKLHGVGKVTATRLDRLGIQTCAQLRDWPLIDLHREFGAFGRRLYELSRGIDERPVQADQER
KSVSVETTYVTDLTTLEQCADEIRRLVVQLDARIDRAGAARSIRKLYVKIRFADFQRTTVECVADATNAETAVTLLAKGL
LRRAQPVRLLGVGVRIDEDTAERHGQFLLFDDEVGDDTPAP
>Mature_361_residues
MRKIIHCDCDCFYASVEMRDDPSLRNRPLAVGGRPDQRGVIATCNYEARRYGVHSAMSSALAMRKCPDLLILPSAMDKYR
AASRQIMAIYRDYTPDVEPLSLDEAYLDVSGSERCQGSATLIAREIRERVRDTVGVTVSAGVAPNKFIAKIASDWNKPDG
LFVVRPHEIDAFVAALPVRKLHGVGKVTATRLDRLGIQTCAQLRDWPLIDLHREFGAFGRRLYELSRGIDERPVQADQER
KSVSVETTYVTDLTTLEQCADEIRRLVVQLDARIDRAGAARSIRKLYVKIRFADFQRTTVECVADATNAETAVTLLAKGL
LRRAQPVRLLGVGVRIDEDTAERHGQFLLFDDEVGDDTPAP

Specific function: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits

COG id: COG0389

COG function: function code L; Nucleotidyltransferase/DNA polymerase involved in DNA repair

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 umuC domain [H]

Homologues:

Organism=Homo sapiens, GI84043967, Length=341, Percent_Identity=28.4457478005865, Blast_Score=152, Evalue=3e-37,
Organism=Homo sapiens, GI7706681, Length=342, Percent_Identity=28.3625730994152, Blast_Score=152, Evalue=5e-37,
Organism=Homo sapiens, GI154350220, Length=314, Percent_Identity=30.8917197452229, Blast_Score=138, Evalue=1e-32,
Organism=Homo sapiens, GI7705344, Length=107, Percent_Identity=48.5981308411215, Blast_Score=119, Evalue=6e-27,
Organism=Homo sapiens, GI5729982, Length=366, Percent_Identity=28.9617486338798, Blast_Score=114, Evalue=2e-25,
Organism=Escherichia coli, GI1786425, Length=346, Percent_Identity=47.3988439306358, Blast_Score=316, Evalue=2e-87,
Organism=Escherichia coli, GI1787432, Length=232, Percent_Identity=29.7413793103448, Blast_Score=88, Evalue=8e-19,
Organism=Caenorhabditis elegans, GI193205700, Length=422, Percent_Identity=29.1469194312796, Blast_Score=149, Evalue=2e-36,
Organism=Caenorhabditis elegans, GI17537959, Length=284, Percent_Identity=30.2816901408451, Blast_Score=125, Evalue=4e-29,
Organism=Caenorhabditis elegans, GI193205702, Length=367, Percent_Identity=26.9754768392371, Blast_Score=107, Evalue=8e-24,
Organism=Caenorhabditis elegans, GI115534089, Length=125, Percent_Identity=38.4, Blast_Score=76, Evalue=3e-14,
Organism=Saccharomyces cerevisiae, GI6324921, Length=206, Percent_Identity=28.1553398058252, Blast_Score=72, Evalue=1e-13,
Organism=Drosophila melanogaster, GI19923006, Length=344, Percent_Identity=26.7441860465116, Blast_Score=131, Evalue=7e-31,
Organism=Drosophila melanogaster, GI21355641, Length=283, Percent_Identity=30.0353356890459, Blast_Score=119, Evalue=3e-27,
Organism=Drosophila melanogaster, GI24644984, Length=283, Percent_Identity=30.0353356890459, Blast_Score=119, Evalue=3e-27,
Organism=Drosophila melanogaster, GI24668444, Length=149, Percent_Identity=32.2147651006711, Blast_Score=70, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017962
- InterPro:   IPR017961
- InterPro:   IPR001126
- InterPro:   IPR017963
- InterPro:   IPR022880 [H]

Pfam domain/function: PF00817 IMS [H]

EC number: =2.7.7.7 [H]

Molecular weight: Translated: 40332; Mature: 40332

Theoretical pI: Translated: 7.69; Mature: 7.69

Prosite motif: PS50173 UMUC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRKIIHCDCDCFYASVEMRDDPSLRNRPLAVGGRPDQRGVIATCNYEARRYGVHSAMSSA
CCCEEEECCCEEEEEEEECCCCCCCCCCEEECCCCCCCCEEEEECCHHHHHHHHHHHHHH
LAMRKCPDLLILPSAMDKYRAASRQIMAIYRDYTPDVEPLSLDEAYLDVSGSERCQGSAT
HHHHHCCCEEEECCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHEEECCCCCCCCCHHH
LIAREIRERVRDTVGVTVSAGVAPNKFIAKIASDWNKPDGLFVVRPHEIDAFVAALPVRK
HHHHHHHHHHHHHHCEEEECCCCCHHHHHHHHHCCCCCCCEEEECCCHHHHHHHHHHHHH
LHGVGKVTATRLDRLGIQTCAQLRDWPLIDLHREFGAFGRRLYELSRGIDERPVQADQER
HHCCCHHHHHHHHHHHHHHHHHHCCCCEEHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHH
KSVSVETTYVTDLTTLEQCADEIRRLVVQLDARIDRAGAARSIRKLYVKIRFADFQRTTV
HCEEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEECCHHHHH
ECVADATNAETAVTLLAKGLLRRAQPVRLLGVGVRIDEDTAERHGQFLLFDDEVGDDTPA
HHHHCCCCHHHHHHHHHHHHHHHCCCEEEEEEEEEECCHHHHHCCCEEEEECCCCCCCCC
P
C
>Mature Secondary Structure
MRKIIHCDCDCFYASVEMRDDPSLRNRPLAVGGRPDQRGVIATCNYEARRYGVHSAMSSA
CCCEEEECCCEEEEEEEECCCCCCCCCCEEECCCCCCCCEEEEECCHHHHHHHHHHHHHH
LAMRKCPDLLILPSAMDKYRAASRQIMAIYRDYTPDVEPLSLDEAYLDVSGSERCQGSAT
HHHHHCCCEEEECCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHEEECCCCCCCCCHHH
LIAREIRERVRDTVGVTVSAGVAPNKFIAKIASDWNKPDGLFVVRPHEIDAFVAALPVRK
HHHHHHHHHHHHHHCEEEECCCCCHHHHHHHHHCCCCCCCEEEECCCHHHHHHHHHHHHH
LHGVGKVTATRLDRLGIQTCAQLRDWPLIDLHREFGAFGRRLYELSRGIDERPVQADQER
HHCCCHHHHHHHHHHHHHHHHHHCCCCEEHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHH
KSVSVETTYVTDLTTLEQCADEIRRLVVQLDARIDRAGAARSIRKLYVKIRFADFQRTTV
HCEEEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEECCHHHHH
ECVADATNAETAVTLLAKGLLRRAQPVRLLGVGVRIDEDTAERHGQFLLFDDEVGDDTPA
HHHHCCCCHHHHHHHHHHHHHHHCCCEEEEEEEEEECCHHHHHCCCEEEEECCCCCCCCC
P
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11823852 [H]