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The map label for this gene is aceE [H]

Identifier: 116690158

GI number: 116690158

Start: 2370814

End: 2373510

Strand: Reverse

Name: aceE [H]

Synonym: Bcen2424_2137

Alternate gene names: 116690158

Gene position: 2373510-2370814 (Counterclockwise)

Preceding gene: 116690163

Following gene: 116690157

Centisome position: 68.13

GC content: 64.22

Gene sequence:

>2697_bases
ATGTCCGCTGTACCGAACGAAGTGATGAAATATGTCGCCGCCGAACGTGACGACGACCCGCAAGAAACCGTCGAGTGGCT
GGAGTCGCTCGATGGCGTGATCTCCTCCGTGGGCACCGGCCGTGCGCATTACCTGATCGAAAAGCAGATCGAATTCGCCC
GCATGCACGGCGAACACCTGCCGTTCTCCGCCAATACCCCGTACATCAACACGATTCCGGTCGAAGCCCAGGCAAAGATT
CCGGGCGACCAGGACATCGAGCACCGCATCCGTTCGTACACGCGCTGGAACGCGCTGGCGATGGTGCTGCGCGCAGGCAA
GGACACGAACGTCGGCGGCCACATCGCGTCGTTCGCATCGGCCGCGACGCTCTACGACGTCGGCTACAACCACTTCTGGC
ACGCAGCATCCGACCAGCACGGCGGCGATCTCGTGTTCGTGCAGGGCCACTCGTCGCCGGGCGTGTACTCGCGCGCGTTC
CTGCTCGGCCGCCTGAAGGAAGAGCAGCTCGACAACTTCCGCCAGGAAGTCGACGGCAAGGGTATCTCGTCGTACCCGCA
CCCGTGGCTGATGCCGGATTTCTGGCAGTTCCCGACCGTGTCGATGGGCCTCGGCCCGATCATGGCGATCTACCAGGCCC
GCTTCATGAAGTACCTGGAGTCGCGCGGCATCGCGAAGACGGAAGGCCGCAAGGTGTGGGCGTTCCTCGGCGACGGCGAG
ACGGACGAGCCGGAATCGCTCGGCGCGATCGGCATGGCGAGCCGCGAGAAGCTCGACAACCTCGTGTTCGTGATCAACTG
CAACCTGCAGCGTCTCGACGGCCCGGTGCGCGGCAACGGCAAGATCATCCAGGAACTCGAATCGGAATTCCGCGGCGCCG
GCTGGAACGTGATCAAGGTCATCTGGGGCAGCCGCTGGGATGCGCTGTTCGCGCGCGACAAGTCGGGCGCGCTGATGCGC
CGCATGATGGAGTGCGTCGACGGCGAATACCAGACGTACAAGTCGGAGTCGGGCGCGTACGTTCGCGAGCACTTCTTCAA
CACGCCTGAACTGAAGGCGCTCGTCGCCGACTGGTCGGACGACGACATCTGGGCGCTGAACCGCGGCGGTCACGATCCGC
ACAAGATCTACGCGGCATTCCACGAAGCCACGAACACGAAGGGCGCGCCGACCGTCATCCTCGCGAAGACCATCAAGGGC
TACGGGATGGGCGAGTCGGGCCAGGCGATGAACATCACGCACCAGCAGAAGAAGCTGCCGGTCGAGCAACTGAAGAAGTT
CCGTGACCAGTTCCGCCTGCCGATCACCGACGAGCAGATCGCCGACGTGCCGTACCTGAAGTTCGAGGAAGGCTCGAAGG
AACTCGAATACATGCGCCAGAAGCGCATGGACCTCGGCGGCTACTTGCCGCACCGCCGCGAGAAGGCGACGTCGCTGCCG
GTGCCGGCGCTCGACGCGTTCGAGCCGCTCCTGAAGGGCACGGGCGAAGGCCGCGAGATCTCGACGACGATGGCGTTCGT
GCGGATTCTGAACATCCTGCTGAAGGACAAGGCGCTCGGCAAGCGCGTCGTGCCGATCGTCCCGGACGAATCGCGTACGT
TCGGCATGGAAGGCCTGTTCCGCCAGATCGGTATCTGGAACCAGGAAGGCCAGAAGTACGTGCCGGAAGATTCTGACCAG
CTGATGTTCTACAAGGAATCGCAGACCGGCCAGATCCTGCAGGAAGGCATCAACGAAGCGGGCGGCATGTGCGACTGGAT
CGCGGCGGCGACGTCGTATTCGACGCACGGCGAGATCATGGTGCCGTTCTACATCTTCTACTCGATGTTCGGCTTCCAGC
GGATCGGCGACCTCGCCTGGGCCGCGGGCGACATGCGTTCGCGCGGCTTCCTGCTGGGCGGCACCGCGGGCCGTACGACG
CTGAACGGCGAAGGCCTGCAGCACGAAGACGGTCACTCGCTCCTGTGGGCGGCATCGGTGCCGAACTGCGTGAGCTACGA
CCCGACGTTCGGCTACGAACTCGCGGTGATCATCCAGGACGGCCTGCGCCGCATGGTGCAGGACCAGGAAGACGTGTACT
ACTACATCACGGTGATGAACGAGAACTACGAGCACCCGGCGATTCCGCAGGGCGAGCACGTGGCGGCTGACATCATCAAG
GGCATGTACGCGTTCAAGAAGGCCGACGCCGACAAGAAGGCGCCGCGCGTCCAGTTGCTCGGCGCGGGCACGATCTTCAA
CGAAGTGATCGCCGCCGCCGACCTGCTGAAGAACGACTGGGGCGTCGCCGCCGACCTGTGGAGCGTGCCGAGCTTCACCG
AACTCGCGCGCGAAGGCCATGAGGTCGAGCGCTGGAACCTGCTCCATCCGACCGAGGAGCGTCGCCTGTCGCACGTGCAG
AAGTGCCTGAAGGACACGCAGGGCCCGGTCATCGCATCGACCGACTACGTCCGTGCGCTGGTCGACCAGATCCGTGGCCA
GATCGATCGCCGCTTCGTCGTGCTGGGCACCGACGGCTTCGGTCGTTCGGACACCCGCGAGAAGCTGCGTCACTTCTTCG
AGGTCGACCGTCACTGGGTCACCGTCGCCGCGCTCAACGCGCTGGCCGACGAAGGCACGATCGAGCGCAAGGTGGTCGCG
GACGCGATCGCCAAGTACAACCTCGATCCGTCCAAGCCCAACCCGATGACCGTTTAA

Upstream 100 bases:

>100_bases
GTCCACGCTCATTACAATCCGTCGGAGCTTGCCCGCAGCCGGCCGCGTCGCGTCGTCTGCACGAGAGCGATCCTCACATT
CCAGGACCCAGGAGACGAGA

Downstream 100 bases:

>100_bases
CGCACACGCCGTGTGATGCCGCGCGCCGCTCCCGCGAGGAGCGCGCGCGGCCATGGAGACAGAAACAGATGAGTCAAGCG
ATCGAAGTGAAGGTGCCGGA

Product: pyruvate dehydrogenase subunit E1

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 898; Mature: 897

Protein sequence:

>898_residues
MSAVPNEVMKYVAAERDDDPQETVEWLESLDGVISSVGTGRAHYLIEKQIEFARMHGEHLPFSANTPYINTIPVEAQAKI
PGDQDIEHRIRSYTRWNALAMVLRAGKDTNVGGHIASFASAATLYDVGYNHFWHAASDQHGGDLVFVQGHSSPGVYSRAF
LLGRLKEEQLDNFRQEVDGKGISSYPHPWLMPDFWQFPTVSMGLGPIMAIYQARFMKYLESRGIAKTEGRKVWAFLGDGE
TDEPESLGAIGMASREKLDNLVFVINCNLQRLDGPVRGNGKIIQELESEFRGAGWNVIKVIWGSRWDALFARDKSGALMR
RMMECVDGEYQTYKSESGAYVREHFFNTPELKALVADWSDDDIWALNRGGHDPHKIYAAFHEATNTKGAPTVILAKTIKG
YGMGESGQAMNITHQQKKLPVEQLKKFRDQFRLPITDEQIADVPYLKFEEGSKELEYMRQKRMDLGGYLPHRREKATSLP
VPALDAFEPLLKGTGEGREISTTMAFVRILNILLKDKALGKRVVPIVPDESRTFGMEGLFRQIGIWNQEGQKYVPEDSDQ
LMFYKESQTGQILQEGINEAGGMCDWIAAATSYSTHGEIMVPFYIFYSMFGFQRIGDLAWAAGDMRSRGFLLGGTAGRTT
LNGEGLQHEDGHSLLWAASVPNCVSYDPTFGYELAVIIQDGLRRMVQDQEDVYYYITVMNENYEHPAIPQGEHVAADIIK
GMYAFKKADADKKAPRVQLLGAGTIFNEVIAAADLLKNDWGVAADLWSVPSFTELAREGHEVERWNLLHPTEERRLSHVQ
KCLKDTQGPVIASTDYVRALVDQIRGQIDRRFVVLGTDGFGRSDTREKLRHFFEVDRHWVTVAALNALADEGTIERKVVA
DAIAKYNLDPSKPNPMTV

Sequences:

>Translated_898_residues
MSAVPNEVMKYVAAERDDDPQETVEWLESLDGVISSVGTGRAHYLIEKQIEFARMHGEHLPFSANTPYINTIPVEAQAKI
PGDQDIEHRIRSYTRWNALAMVLRAGKDTNVGGHIASFASAATLYDVGYNHFWHAASDQHGGDLVFVQGHSSPGVYSRAF
LLGRLKEEQLDNFRQEVDGKGISSYPHPWLMPDFWQFPTVSMGLGPIMAIYQARFMKYLESRGIAKTEGRKVWAFLGDGE
TDEPESLGAIGMASREKLDNLVFVINCNLQRLDGPVRGNGKIIQELESEFRGAGWNVIKVIWGSRWDALFARDKSGALMR
RMMECVDGEYQTYKSESGAYVREHFFNTPELKALVADWSDDDIWALNRGGHDPHKIYAAFHEATNTKGAPTVILAKTIKG
YGMGESGQAMNITHQQKKLPVEQLKKFRDQFRLPITDEQIADVPYLKFEEGSKELEYMRQKRMDLGGYLPHRREKATSLP
VPALDAFEPLLKGTGEGREISTTMAFVRILNILLKDKALGKRVVPIVPDESRTFGMEGLFRQIGIWNQEGQKYVPEDSDQ
LMFYKESQTGQILQEGINEAGGMCDWIAAATSYSTHGEIMVPFYIFYSMFGFQRIGDLAWAAGDMRSRGFLLGGTAGRTT
LNGEGLQHEDGHSLLWAASVPNCVSYDPTFGYELAVIIQDGLRRMVQDQEDVYYYITVMNENYEHPAIPQGEHVAADIIK
GMYAFKKADADKKAPRVQLLGAGTIFNEVIAAADLLKNDWGVAADLWSVPSFTELAREGHEVERWNLLHPTEERRLSHVQ
KCLKDTQGPVIASTDYVRALVDQIRGQIDRRFVVLGTDGFGRSDTREKLRHFFEVDRHWVTVAALNALADEGTIERKVVA
DAIAKYNLDPSKPNPMTV
>Mature_897_residues
SAVPNEVMKYVAAERDDDPQETVEWLESLDGVISSVGTGRAHYLIEKQIEFARMHGEHLPFSANTPYINTIPVEAQAKIP
GDQDIEHRIRSYTRWNALAMVLRAGKDTNVGGHIASFASAATLYDVGYNHFWHAASDQHGGDLVFVQGHSSPGVYSRAFL
LGRLKEEQLDNFRQEVDGKGISSYPHPWLMPDFWQFPTVSMGLGPIMAIYQARFMKYLESRGIAKTEGRKVWAFLGDGET
DEPESLGAIGMASREKLDNLVFVINCNLQRLDGPVRGNGKIIQELESEFRGAGWNVIKVIWGSRWDALFARDKSGALMRR
MMECVDGEYQTYKSESGAYVREHFFNTPELKALVADWSDDDIWALNRGGHDPHKIYAAFHEATNTKGAPTVILAKTIKGY
GMGESGQAMNITHQQKKLPVEQLKKFRDQFRLPITDEQIADVPYLKFEEGSKELEYMRQKRMDLGGYLPHRREKATSLPV
PALDAFEPLLKGTGEGREISTTMAFVRILNILLKDKALGKRVVPIVPDESRTFGMEGLFRQIGIWNQEGQKYVPEDSDQL
MFYKESQTGQILQEGINEAGGMCDWIAAATSYSTHGEIMVPFYIFYSMFGFQRIGDLAWAAGDMRSRGFLLGGTAGRTTL
NGEGLQHEDGHSLLWAASVPNCVSYDPTFGYELAVIIQDGLRRMVQDQEDVYYYITVMNENYEHPAIPQGEHVAADIIKG
MYAFKKADADKKAPRVQLLGAGTIFNEVIAAADLLKNDWGVAADLWSVPSFTELAREGHEVERWNLLHPTEERRLSHVQK
CLKDTQGPVIASTDYVRALVDQIRGQIDRRFVVLGTDGFGRSDTREKLRHFFEVDRHWVTVAALNALADEGTIERKVVAD
AIAKYNLDPSKPNPMTV

Specific function: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components:pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydroge

COG id: COG2609

COG function: function code C; Pyruvate dehydrogenase complex, dehydrogenase (E1) component

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1786304, Length=885, Percent_Identity=59.6610169491525, Blast_Score=1084, Evalue=0.0,

Paralogues:

None

Copy number: 1140 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 400 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). 6,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004660
- InterPro:   IPR009014
- InterPro:   IPR015941
- InterPro:   IPR005474 [H]

Pfam domain/function: PF00456 Transketolase_N [H]

EC number: =1.2.4.1 [H]

Molecular weight: Translated: 100870; Mature: 100739

Theoretical pI: Translated: 5.77; Mature: 5.77

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAVPNEVMKYVAAERDDDPQETVEWLESLDGVISSVGTGRAHYLIEKQIEFARMHGEHL
CCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCC
PFSANTPYINTIPVEAQAKIPGDQDIEHRIRSYTRWNALAMVLRAGKDTNVGGHIASFAS
CCCCCCCEEEEECCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHH
AATLYDVGYNHFWHAASDQHGGDLVFVQGHSSPGVYSRAFLLGRLKEEQLDNFRQEVDGK
HHHHHHCCCHHEECCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCC
GISSYPHPWLMPDFWQFPTVSMGLGPIMAIYQARFMKYLESRGIAKTEGRKVWAFLGDGE
CCCCCCCCCCCCCCCCCCCCHHCHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCC
TDEPESLGAIGMASREKLDNLVFVINCNLQRLDGPVRGNGKIIQELESEFRGAGWNVIKV
CCCCHHCCCCCCCCHHHHCCEEEEEECCHHHCCCCCCCCCHHHHHHHHHHCCCCCEEEEE
IWGSRWDALFARDKSGALMRRMMECVDGEYQTYKSESGAYVREHFFNTPELKALVADWSD
ECCCCCHHHEECCCCCHHHHHHHHHHCCCHHHHCCCCCCHHHHHCCCCCHHHEEEECCCC
DDIWALNRGGHDPHKIYAAFHEATNTKGAPTVILAKTIKGYGMGESGQAMNITHQQKKLP
CCEEEECCCCCCHHHHHHHHHHHCCCCCCCEEEEEEHHCCCCCCCCCCEECCCHHHHCCC
VEQLKKFRDQFRLPITDEQIADVPYLKFEEGSKELEYMRQKRMDLGGYLPHRREKATSLP
HHHHHHHHHHCCCCCCCHHHCCCCCEEECCCCHHHHHHHHHHHCCCCCCCCCHHHCCCCC
VPALDAFEPLLKGTGEGREISTTMAFVRILNILLKDKALGKRVVPIVPDESRTFGMEGLF
CCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCEECCCCCCCCCHHHHH
RQIGIWNQEGQKYVPEDSDQLMFYKESQTGQILQEGINEAGGMCDWIAAATSYSTHGEIM
HHHCCCCCCCCCCCCCCCCCEEEEECCCCHHHHHHHHHHHCCHHHHHHHHCCCCCCCCEE
VPFYIFYSMFGFQRIGDLAWAAGDMRSRGFLLGGTAGRTTLNGEGLQHEDGHSLLWAASV
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCEECCCCCCCCCCCEEEEECCC
PNCVSYDPTFGYELAVIIQDGLRRMVQDQEDVYYYITVMNENYEHPAIPQGEHVAADIIK
CCCCCCCCCCCCEEEHHHHHHHHHHHCCCCCEEEEEEEECCCCCCCCCCCCCHHHHHHHH
GMYAFKKADADKKAPRVQLLGAGTIFNEVIAAADLLKNDWGVAADLWSVPSFTELAREGH
HHHHHHHCCCCCCCCEEEEEECHHHHHHHHHHHHHHHCCCCCCHHHHCCCCHHHHHHCCC
EVERWNLLHPTEERRLSHVQKCLKDTQGPVIASTDYVRALVDQIRGQIDRRFVVLGTDGF
CCCCCCCCCCCHHHHHHHHHHHHHHCCCCEEECHHHHHHHHHHHHHHHCCEEEEEECCCC
GRSDTREKLRHFFEVDRHWVTVAALNALADEGTIERKVVADAIAKYNLDPSKPNPMTV
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure 
SAVPNEVMKYVAAERDDDPQETVEWLESLDGVISSVGTGRAHYLIEKQIEFARMHGEHL
CCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCC
PFSANTPYINTIPVEAQAKIPGDQDIEHRIRSYTRWNALAMVLRAGKDTNVGGHIASFAS
CCCCCCCEEEEECCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHH
AATLYDVGYNHFWHAASDQHGGDLVFVQGHSSPGVYSRAFLLGRLKEEQLDNFRQEVDGK
HHHHHHCCCHHEECCCCCCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCC
GISSYPHPWLMPDFWQFPTVSMGLGPIMAIYQARFMKYLESRGIAKTEGRKVWAFLGDGE
CCCCCCCCCCCCCCCCCCCCHHCHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCC
TDEPESLGAIGMASREKLDNLVFVINCNLQRLDGPVRGNGKIIQELESEFRGAGWNVIKV
CCCCHHCCCCCCCCHHHHCCEEEEEECCHHHCCCCCCCCCHHHHHHHHHHCCCCCEEEEE
IWGSRWDALFARDKSGALMRRMMECVDGEYQTYKSESGAYVREHFFNTPELKALVADWSD
ECCCCCHHHEECCCCCHHHHHHHHHHCCCHHHHCCCCCCHHHHHCCCCCHHHEEEECCCC
DDIWALNRGGHDPHKIYAAFHEATNTKGAPTVILAKTIKGYGMGESGQAMNITHQQKKLP
CCEEEECCCCCCHHHHHHHHHHHCCCCCCCEEEEEEHHCCCCCCCCCCEECCCHHHHCCC
VEQLKKFRDQFRLPITDEQIADVPYLKFEEGSKELEYMRQKRMDLGGYLPHRREKATSLP
HHHHHHHHHHCCCCCCCHHHCCCCCEEECCCCHHHHHHHHHHHCCCCCCCCCHHHCCCCC
VPALDAFEPLLKGTGEGREISTTMAFVRILNILLKDKALGKRVVPIVPDESRTFGMEGLF
CCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCEECCCCCCCCCHHHHH
RQIGIWNQEGQKYVPEDSDQLMFYKESQTGQILQEGINEAGGMCDWIAAATSYSTHGEIM
HHHCCCCCCCCCCCCCCCCCEEEEECCCCHHHHHHHHHHHCCHHHHHHHHCCCCCCCCEE
VPFYIFYSMFGFQRIGDLAWAAGDMRSRGFLLGGTAGRTTLNGEGLQHEDGHSLLWAASV
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCEECCCCCCCCCCCEEEEECCC
PNCVSYDPTFGYELAVIIQDGLRRMVQDQEDVYYYITVMNENYEHPAIPQGEHVAADIIK
CCCCCCCCCCCCEEEHHHHHHHHHHHCCCCCEEEEEEEECCCCCCCCCCCCCHHHHHHHH
GMYAFKKADADKKAPRVQLLGAGTIFNEVIAAADLLKNDWGVAADLWSVPSFTELAREGH
HHHHHHHCCCCCCCCEEEEEECHHHHHHHHHHHHHHHCCCCCCHHHHCCCCHHHHHHCCC
EVERWNLLHPTEERRLSHVQKCLKDTQGPVIASTDYVRALVDQIRGQIDRRFVVLGTDGF
CCCCCCCCCCCHHHHHHHHHHHHHHCCCCEEECHHHHHHHHHHHHHHHCCEEEEEECCCC
GRSDTREKLRHFFEVDRHWVTVAALNALADEGTIERKVVADAIAKYNLDPSKPNPMTV
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8021225 [H]