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The map label for this gene is pccB [H]

Identifier: 116689293

GI number: 116689293

Start: 1401981

End: 1402910

Strand: Direct

Name: pccB [H]

Synonym: Bcen2424_1271

Alternate gene names: 116689293

Gene position: 1401981-1402910 (Clockwise)

Preceding gene: 116689292

Following gene: 116689294

Centisome position: 40.24

GC content: 70.54

Gene sequence:

>930_bases
ATGATGAGCGATATTCGTCATATCCATGACGCCCCCGCGTTCGTCGCGAACGCGGCGAGCTGGTACGAAGCGTCGGCGCG
GCAACGCATCGACGGGCTGCTCGACGCGGGCAGCTTCACGGAATTCCTCGGGCCGGCCGAGCGCGTGACGAGCCCGCACC
TGCCGCTGTTCGCGCTGCCGCAGCAGTTCGACGACGGGATGGTGGTCGGCCACGGCCGGCTCGATGGCAAGCCGGTGTTC
GTCGCCGCGCAGGAGGGCCGCTTCATGGGCGGCGCGTTCGGCGAAGTGCACGGCGCGAAGCTCACCGGGCTGCTGCGCGC
CGCGCGTGACGTCGGCAAGCCGGTGCTGATCCTGTTCGACACGGGCGGCGTGCGGTTGCAGGAAGCGAACGCGGGCGAGC
TCGCGATCGCCGAGATCATGCGCGCGCTCGTCGACGCGCGGGCGGCCGGCGTGCCGGTGATCGGGCTGATCGGCGGGCGC
GCGGGCTGCTACGGCGGCGGCGGGTTGCTCGCCGCGTGCTGTTCGGCGCTCGCGGTGTCGGAGCAGGGGCGCATCAGCGT
GTCGGGGCCTGAAGTGATCGAGACCAATCGCGGCGTCGAGGAATTCGACTCGAAGGATCGCGCGCTGATCTGGCGCACGA
TGGGCGGCAAGCATCGCCGCTTGATCGGCGGCGCCGATCGTTACGTGGCCGATACGCCGGACGCGTTCCGCGCGGCCGCG
CTCGACCTGATCGGCCGCGCGCCGACGTTCGATGCGGCGATGCTGCGTGAGGAACAGGCGCGTCTCGAAGCACGGATCGA
GCGGTTCGGCGGCTGCCGGGATGCGCTCGACGTGTGGCGTGCGCTCGGGGCCGACGCGCCGGAAGCGATTCCGGGCATGT
CCGACGACGAATTCGCGAAGCTCGCCGACCAGTTACAGGAGCAGAAATGA

Upstream 100 bases:

>100_bases
CGCCGGGCGGCCTGAAGCTGTCGATCAACGACGGCGGCGCGCGGCCCGACATGGTGTCGCTGCGGCTCGCGCAGGCCGTG
CGCGCGATCGAGGGGGACGC

Downstream 100 bases:

>100_bases
AACGACCCCCACGCTCACTTCGTTCGCTGCCCCCCGAGGGGGCGCCTGCCTCCCTTGGGGCGGCCCGGCGGGAGGCAGCA
TGACGCTCGATGAAGTACTG

Product: malonate decarboxylase subunit beta

Products: NA

Alternate protein names: PCCase; Propanoyl-CoA:carbon dioxide ligase [H]

Number of amino acids: Translated: 309; Mature: 309

Protein sequence:

>309_residues
MMSDIRHIHDAPAFVANAASWYEASARQRIDGLLDAGSFTEFLGPAERVTSPHLPLFALPQQFDDGMVVGHGRLDGKPVF
VAAQEGRFMGGAFGEVHGAKLTGLLRAARDVGKPVLILFDTGGVRLQEANAGELAIAEIMRALVDARAAGVPVIGLIGGR
AGCYGGGGLLAACCSALAVSEQGRISVSGPEVIETNRGVEEFDSKDRALIWRTMGGKHRRLIGGADRYVADTPDAFRAAA
LDLIGRAPTFDAAMLREEQARLEARIERFGGCRDALDVWRALGADAPEAIPGMSDDEFAKLADQLQEQK

Sequences:

>Translated_309_residues
MMSDIRHIHDAPAFVANAASWYEASARQRIDGLLDAGSFTEFLGPAERVTSPHLPLFALPQQFDDGMVVGHGRLDGKPVF
VAAQEGRFMGGAFGEVHGAKLTGLLRAARDVGKPVLILFDTGGVRLQEANAGELAIAEIMRALVDARAAGVPVIGLIGGR
AGCYGGGGLLAACCSALAVSEQGRISVSGPEVIETNRGVEEFDSKDRALIWRTMGGKHRRLIGGADRYVADTPDAFRAAA
LDLIGRAPTFDAAMLREEQARLEARIERFGGCRDALDVWRALGADAPEAIPGMSDDEFAKLADQLQEQK
>Mature_309_residues
MMSDIRHIHDAPAFVANAASWYEASARQRIDGLLDAGSFTEFLGPAERVTSPHLPLFALPQQFDDGMVVGHGRLDGKPVF
VAAQEGRFMGGAFGEVHGAKLTGLLRAARDVGKPVLILFDTGGVRLQEANAGELAIAEIMRALVDARAAGVPVIGLIGGR
AGCYGGGGLLAACCSALAVSEQGRISVSGPEVIETNRGVEEFDSKDRALIWRTMGGKHRRLIGGADRYVADTPDAFRAAA
LDLIGRAPTFDAAMLREEQARLEARIERFGGCRDALDVWRALGADAPEAIPGMSDDEFAKLADQLQEQK

Specific function: This Protein Is A Component Of The Acetyl Coenzyme A Carboxylase Complex; First, Biotin Carboxylase Catalyzes The Carboxylation Of The Carrier Protein And Then The Transcarboxylase Transfers The Carboxyl Group To Form Malonyl-CoA. [C]

COG id: COG0777

COG function: function code I; Acetyl-CoA carboxylase beta subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 carboxyltransferase domain [H]

Homologues:

Organism=Homo sapiens, GI119943100, Length=182, Percent_Identity=33.5164835164835, Blast_Score=72, Evalue=5e-13,
Organism=Escherichia coli, GI1788655, Length=183, Percent_Identity=31.6939890710383, Blast_Score=65, Evalue=8e-12,
Organism=Caenorhabditis elegans, GI25147362, Length=182, Percent_Identity=32.4175824175824, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI25147359, Length=182, Percent_Identity=32.4175824175824, Blast_Score=80, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000438
- InterPro:   IPR000022
- InterPro:   IPR011763
- InterPro:   IPR011762 [H]

Pfam domain/function: PF01039 Carboxyl_trans [H]

EC number: =6.4.1.3 [H]

Molecular weight: Translated: 32851; Mature: 32851

Theoretical pI: Translated: 5.10; Mature: 5.10

Prosite motif: PS50980 COA_CT_NTER ; PS50989 COA_CT_CTER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMSDIRHIHDAPAFVANAASWYEASARQRIDGLLDAGSFTEFLGPAERVTSPHLPLFALP
CCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCHHHHCCCCCCEEECC
QQFDDGMVVGHGRLDGKPVFVAAQEGRFMGGAFGEVHGAKLTGLLRAARDVGKPVLILFD
CCCCCCEEEECCCCCCCEEEEEECCCCCCCCCCHHHCHHHHHHHHHHHHHCCCCEEEEEC
TGGVRLQEANAGELAIAEIMRALVDARAAGVPVIGLIGGRAGCYGGGGLLAACCSALAVS
CCCEEEEECCCCCHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHC
EQGRISVSGPEVIETNRGVEEFDSKDRALIWRTMGGKHRRLIGGADRYVADTPDAFRAAA
CCCEEEECCCCCEECCCCHHHHCCCCCEEEEECCCCCCEEEECCCCCCCCCCCHHHHHHH
LDLIGRAPTFDAAMLREEQARLEARIERFGGCRDALDVWRALGADAPEAIPGMSDDEFAK
HHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCHHCCCCCCHHHHH
LADQLQEQK
HHHHHHHCC
>Mature Secondary Structure
MMSDIRHIHDAPAFVANAASWYEASARQRIDGLLDAGSFTEFLGPAERVTSPHLPLFALP
CCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCHHHHCCCCCCEEECC
QQFDDGMVVGHGRLDGKPVFVAAQEGRFMGGAFGEVHGAKLTGLLRAARDVGKPVLILFD
CCCCCCEEEECCCCCCCEEEEEECCCCCCCCCCHHHCHHHHHHHHHHHHHCCCCEEEEEC
TGGVRLQEANAGELAIAEIMRALVDARAAGVPVIGLIGGRAGCYGGGGLLAACCSALAVS
CCCEEEEECCCCCHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHC
EQGRISVSGPEVIETNRGVEEFDSKDRALIWRTMGGKHRRLIGGADRYVADTPDAFRAAA
CCCEEEECCCCCEECCCCHHHHCCCCCEEEEECCCCCCEEEECCCCCCCCCCCHHHHHHH
LDLIGRAPTFDAAMLREEQARLEARIERFGGCRDALDVWRALGADAPEAIPGMSDDEFAK
HHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCHHCCCCCCHHHHH
LADQLQEQK
HHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8830278 [H]