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The map label for this gene is aaeR [H]

Identifier: 116689173

GI number: 116689173

Start: 1262279

End: 1263196

Strand: Reverse

Name: aaeR [H]

Synonym: Bcen2424_1151

Alternate gene names: 116689173

Gene position: 1263196-1262279 (Counterclockwise)

Preceding gene: 116689176

Following gene: 116689172

Centisome position: 36.26

GC content: 70.37

Gene sequence:

>918_bases
ATGAACGATAAAGCGCGGGATCTGAACGATCTCTACTACTTCGTGCAGGTCGTCGAACACGGCGGCTTCGCGCCGGCCGG
GCGCGCGCTGGACATGCCGAAATCGAAGCTGAGCCGCCGCGTCGCGCTGCTCGAAGCGCGGCTCGGGATGCGGCTGATCC
AGCGTTCGACGCGCCGCTTCACGGTCACCGACGTCGGCCAGACCTATTACGCGCATTGCCGCGCGATGCTCGTCGAGGCC
GATGCCGCCGACGAGGCGATCGCGCTGCTGCACGAGGAGCCGCGCGGCATCGTGCGCGTCAGTTGCCCGATCGTGCTGCT
CGATTCGCTGGTCGGCACGATGATCGCCGCGTTCATGGCCGCGTGCCCGCGCGTCGAGATCCACCTGGAAGCGACCAACC
GGCGTGTCGACGTGGTGGGCGAAGGGATCGACGTCGCGATCCGCGTGCGCCCGCCGCCGCTCGAGGACAGCGATCTCGCG
CTGCGTGTGCTCGCCGAACGCGGCCAGTGCCTCGTCGCGAGCCCAGCGCTGCTGCGCGAGCAAGGTGTACCGGCCGTTCC
CGCGGACCTGACGCGCCTGCCGAGCCTCGATCACGGCGTGCCGCAGTCCACGCACGTGTGGCGGCTGCGCGGGCCCGACG
GCGCGCATGCGGAAATCCATCACCAGCCGCGCTACGTGACGGGCGGCATGCTCGCGCTGCGCGCGGCGGCCGTTGCAGGC
GTCGGCGTCGTGCAGTTGCCGACGATGATGGTGCGCGACGAGGTTTCGCGCGGTGAACTGGTCACGGTGCTGCCCGACTG
GGCGCCGCGTCGCGAAATCGTGCACGCGGTGTTCGCGTCGCGCCGCGGGCTGCTGCCGGCGGTGCGGGCGCTACTCGACT
TTCTGGCCGAGCGGTTCGCCGAACTCGAACCCGACTAG

Upstream 100 bases:

>100_bases
GAATTGCGGCGAAACCCGTGTTTCGCATCCATGACTGACAATATAGAGATGGAACGATCGATCCGGTAGACTGCCGAAAT
CGCACTCAGCGTTCCATTTC

Downstream 100 bases:

>100_bases
CGGGGCCGCATCACGCGCGACCACGCGCTGCAGACCACGCACGGGTGCCGTAGACTGCGGTACGCGCAGTGCGCCTTCAG
TGCGCCTTTTTGACAACCCT

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 305; Mature: 305

Protein sequence:

>305_residues
MNDKARDLNDLYYFVQVVEHGGFAPAGRALDMPKSKLSRRVALLEARLGMRLIQRSTRRFTVTDVGQTYYAHCRAMLVEA
DAADEAIALLHEEPRGIVRVSCPIVLLDSLVGTMIAAFMAACPRVEIHLEATNRRVDVVGEGIDVAIRVRPPPLEDSDLA
LRVLAERGQCLVASPALLREQGVPAVPADLTRLPSLDHGVPQSTHVWRLRGPDGAHAEIHHQPRYVTGGMLALRAAAVAG
VGVVQLPTMMVRDEVSRGELVTVLPDWAPRREIVHAVFASRRGLLPAVRALLDFLAERFAELEPD

Sequences:

>Translated_305_residues
MNDKARDLNDLYYFVQVVEHGGFAPAGRALDMPKSKLSRRVALLEARLGMRLIQRSTRRFTVTDVGQTYYAHCRAMLVEA
DAADEAIALLHEEPRGIVRVSCPIVLLDSLVGTMIAAFMAACPRVEIHLEATNRRVDVVGEGIDVAIRVRPPPLEDSDLA
LRVLAERGQCLVASPALLREQGVPAVPADLTRLPSLDHGVPQSTHVWRLRGPDGAHAEIHHQPRYVTGGMLALRAAAVAG
VGVVQLPTMMVRDEVSRGELVTVLPDWAPRREIVHAVFASRRGLLPAVRALLDFLAERFAELEPD
>Mature_305_residues
MNDKARDLNDLYYFVQVVEHGGFAPAGRALDMPKSKLSRRVALLEARLGMRLIQRSTRRFTVTDVGQTYYAHCRAMLVEA
DAADEAIALLHEEPRGIVRVSCPIVLLDSLVGTMIAAFMAACPRVEIHLEATNRRVDVVGEGIDVAIRVRPPPLEDSDLA
LRVLAERGQCLVASPALLREQGVPAVPADLTRLPSLDHGVPQSTHVWRLRGPDGAHAEIHHQPRYVTGGMLALRAAAVAG
VGVVQLPTMMVRDEVSRGELVTVLPDWAPRREIVHAVFASRRGLLPAVRALLDFLAERFAELEPD

Specific function: Activates transcription of the aaeXAB operon [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789639, Length=295, Percent_Identity=30.5084745762712, Blast_Score=146, Evalue=1e-36,
Organism=Escherichia coli, GI1786401, Length=291, Percent_Identity=31.2714776632302, Blast_Score=132, Evalue=3e-32,
Organism=Escherichia coli, GI87081978, Length=303, Percent_Identity=30.3630363036304, Blast_Score=121, Evalue=7e-29,
Organism=Escherichia coli, GI145693193, Length=289, Percent_Identity=29.4117647058824, Blast_Score=114, Evalue=9e-27,
Organism=Escherichia coli, GI1789440, Length=290, Percent_Identity=25.5172413793103, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI1787589, Length=300, Percent_Identity=26, Blast_Score=91, Evalue=8e-20,
Organism=Escherichia coli, GI1787128, Length=295, Percent_Identity=22.7118644067797, Blast_Score=90, Evalue=2e-19,
Organism=Escherichia coli, GI1788297, Length=261, Percent_Identity=26.0536398467433, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1789173, Length=263, Percent_Identity=25.8555133079848, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI157672245, Length=157, Percent_Identity=29.9363057324841, Blast_Score=67, Evalue=2e-12,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 33461; Mature: 33461

Theoretical pI: Translated: 7.06; Mature: 7.06

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNDKARDLNDLYYFVQVVEHGGFAPAGRALDMPKSKLSRRVALLEARLGMRLIQRSTRRF
CCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCEE
TVTDVGQTYYAHCRAMLVEADAADEAIALLHEEPRGIVRVSCPIVLLDSLVGTMIAAFMA
EEEECHHHHHHHHHHHEEECCCCHHHHHHHHCCCCCEEEEECHHHHHHHHHHHHHHHHHH
ACPRVEIHLEATNRRVDVVGEGIDVAIRVRPPPLEDSDLALRVLAERGQCLVASPALLRE
HCCCEEEEEEECCCEEEEEECCCEEEEEECCCCCCCCHHHHHHHHHCCCEEEECHHHHHH
QGVPAVPADLTRLPSLDHGVPQSTHVWRLRGPDGAHAEIHHQPRYVTGGMLALRAAAVAG
CCCCCCCHHHHHCCCCCCCCCCCCEEEEEECCCCCCCEECCCCCEEHHHHHHHHHHHHHC
VGVVQLPTMMVRDEVSRGELVTVLPDWAPRREIVHAVFASRRGLLPAVRALLDFLAERFA
CCHHHHHHHHHHHCCCCCCEEEECCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
ELEPD
HCCCC
>Mature Secondary Structure
MNDKARDLNDLYYFVQVVEHGGFAPAGRALDMPKSKLSRRVALLEARLGMRLIQRSTRRF
CCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCEE
TVTDVGQTYYAHCRAMLVEADAADEAIALLHEEPRGIVRVSCPIVLLDSLVGTMIAAFMA
EEEECHHHHHHHHHHHEEECCCCHHHHHHHHCCCCCEEEEECHHHHHHHHHHHHHHHHHH
ACPRVEIHLEATNRRVDVVGEGIDVAIRVRPPPLEDSDLALRVLAERGQCLVASPALLRE
HCCCEEEEEEECCCEEEEEECCCEEEEEECCCCCCCCHHHHHHHHHCCCEEEECHHHHHH
QGVPAVPADLTRLPSLDHGVPQSTHVWRLRGPDGAHAEIHHQPRYVTGGMLALRAAAVAG
CCCCCCCHHHHHCCCCCCCCCCCCEEEEEECCCCCCCEECCCCCEEHHHHHHHHHHHHHC
VGVVQLPTMMVRDEVSRGELVTVLPDWAPRREIVHAVFASRRGLLPAVRALLDFLAERFA
CCHHHHHHHHHHHCCCCCCEEEECCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
ELEPD
HCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]