Click here to switch to the map view.

The map label for this gene is trxB [H]

Identifier: 116688997

GI number: 116688997

Start: 1081845

End: 1082807

Strand: Reverse

Name: trxB [H]

Synonym: Bcen2424_0974

Alternate gene names: 116688997

Gene position: 1082807-1081845 (Counterclockwise)

Preceding gene: 116689001

Following gene: 116688996

Centisome position: 31.08

GC content: 65.52

Gene sequence:

>963_bases
ATGTCCACGCCCAAACACGCCAAAGTCCTGATTCTCGGTTCCGGCCCCGCCGGCTACACGGCCGCCGTCTACGCGGCACG
CGCCAACCTGTCCCCGGTGCTGATCACCGGCATCGCGCAGGGCGGCCAGCTGATGACCACGACCGACGTCGAAAACTGGC
CGGCTGACGCGAAAGGCGTGCAAGGTCCGGAGCTGATGGCGCGCTTCCAGGAGCACGCGGAGCGCTTCAACACCGAAATC
GTGTTCGACCACATCCACACCGCGAAACTGCACGAGCAGCCGATCCGCCTGATCGGCGACTCGGGCGAATACACGTGCGA
TTCGCTGATCATCGCGACCGGCGCGTCCGCACAGTATCTCGGCCTGCCGTCCGAGGAAGCGTTCATGGGCAAGGGCGTGT
CGGCCTGCGCGACCTGCGACGGCTTCTTCTATCGCAACCAGGAAGTCGCGGTGATCGGCGGGGGCAACACGGCCGTCGAG
GAAGCGCTCTACCTGACCGGCATCGCGAAGAAGGTCACGGTGATCCACCGCCGCGACAAGTTCCGCGCGGAGCCGATCCT
GATCGACCGCCTGCTGGAGAAGCAAAAGGAAGGCGTCGTCGACATCAAGTGGGATCACGTGCTCGACGAGGTGACGGGCG
AGGAGTCGGGCGTCACGGGCCTGCGCATCAAGAACGTGAAGACCGGCGCGACGGAAGACCTGCTCGTACAGGGCGTGTTC
GTCGCGATCGGCCACAAGCCGAACACCGACCTGTTCCAGGGCCAGCTCGAGATGAAGGACGGCTACATCCTGACGAAGAG
CGGCCTGCAAGGCAACGCGACGTCGACGAGCGTGCCGGGCGTGTTCGCCGCGGGCGACGTGCAGGACAACGTGTACCGCC
AGGCGATCACCAGCGCGGGCACCGGCTGCATGGCCGCACTCGACGCGCAGCGCTACCTCGAAAGCCTGCACGACAAGAAG
TAA

Upstream 100 bases:

>100_bases
ATAATGCGCGTCTGATACCCATCTATGACGGCATCCCGGTCACCCCGGATCGCACGGCGAGCCCTACCCCGCCCGCCGGC
CGCCTTTTACGGATTCGCAC

Downstream 100 bases:

>100_bases
GCCGGAAGCCTTTTCACGGCGGGCGCTACAATGGCGTCCGCTGCCGCGAAGCAGGCTCGACCGGAAAGCCGCTGCCGCCG
CGCAGCGGCTTTTTTTTGCC

Product: thioredoxin reductase

Products: NA

Alternate protein names: TRXR [H]

Number of amino acids: Translated: 320; Mature: 319

Protein sequence:

>320_residues
MSTPKHAKVLILGSGPAGYTAAVYAARANLSPVLITGIAQGGQLMTTTDVENWPADAKGVQGPELMARFQEHAERFNTEI
VFDHIHTAKLHEQPIRLIGDSGEYTCDSLIIATGASAQYLGLPSEEAFMGKGVSACATCDGFFYRNQEVAVIGGGNTAVE
EALYLTGIAKKVTVIHRRDKFRAEPILIDRLLEKQKEGVVDIKWDHVLDEVTGEESGVTGLRIKNVKTGATEDLLVQGVF
VAIGHKPNTDLFQGQLEMKDGYILTKSGLQGNATSTSVPGVFAAGDVQDNVYRQAITSAGTGCMAALDAQRYLESLHDKK

Sequences:

>Translated_320_residues
MSTPKHAKVLILGSGPAGYTAAVYAARANLSPVLITGIAQGGQLMTTTDVENWPADAKGVQGPELMARFQEHAERFNTEI
VFDHIHTAKLHEQPIRLIGDSGEYTCDSLIIATGASAQYLGLPSEEAFMGKGVSACATCDGFFYRNQEVAVIGGGNTAVE
EALYLTGIAKKVTVIHRRDKFRAEPILIDRLLEKQKEGVVDIKWDHVLDEVTGEESGVTGLRIKNVKTGATEDLLVQGVF
VAIGHKPNTDLFQGQLEMKDGYILTKSGLQGNATSTSVPGVFAAGDVQDNVYRQAITSAGTGCMAALDAQRYLESLHDKK
>Mature_319_residues
STPKHAKVLILGSGPAGYTAAVYAARANLSPVLITGIAQGGQLMTTTDVENWPADAKGVQGPELMARFQEHAERFNTEIV
FDHIHTAKLHEQPIRLIGDSGEYTCDSLIIATGASAQYLGLPSEEAFMGKGVSACATCDGFFYRNQEVAVIGGGNTAVEE
ALYLTGIAKKVTVIHRRDKFRAEPILIDRLLEKQKEGVVDIKWDHVLDEVTGEESGVTGLRIKNVKTGATEDLLVQGVFV
AIGHKPNTDLFQGQLEMKDGYILTKSGLQGNATSTSVPGVFAAGDVQDNVYRQAITSAGTGCMAALDAQRYLESLHDKK

Specific function: Unknown

COG id: COG0492

COG function: function code O; Thioredoxin reductase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family [H]

Homologues:

Organism=Escherichia coli, GI1787114, Length=321, Percent_Identity=67.9127725856698, Blast_Score=458, Evalue=1e-130,
Organism=Escherichia coli, GI87081763, Length=312, Percent_Identity=34.9358974358974, Blast_Score=143, Evalue=2e-35,
Organism=Saccharomyces cerevisiae, GI6320560, Length=324, Percent_Identity=47.2222222222222, Blast_Score=278, Evalue=1e-75,
Organism=Saccharomyces cerevisiae, GI6321898, Length=322, Percent_Identity=47.2049689440994, Blast_Score=277, Evalue=2e-75,

Paralogues:

None

Copy number: 808 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013027
- InterPro:   IPR008255
- InterPro:   IPR001327
- InterPro:   IPR000103
- InterPro:   IPR005982 [H]

Pfam domain/function: PF00070 Pyr_redox; PF07992 Pyr_redox_2 [H]

EC number: =1.8.1.9 [H]

Molecular weight: Translated: 34335; Mature: 34204

Theoretical pI: Translated: 5.60; Mature: 5.60

Prosite motif: PS00573 PYRIDINE_REDOX_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTPKHAKVLILGSGPAGYTAAVYAARANLSPVLITGIAQGGQLMTTTDVENWPADAKGV
CCCCCCEEEEEEECCCCCCCEEEEEHHCCCCEEEEEEECCCCEEEEECCCCCCCCCCCCC
QGPELMARFQEHAERFNTEIVFDHIHTAKLHEQPIRLIGDSGEYTCDSLIIATGASAQYL
CCHHHHHHHHHHHHHCCCEEEEECHHHHHHHCCCCEEECCCCCCEECEEEEEECCCCEEE
GLPSEEAFMGKGVSACATCDGFFYRNQEVAVIGGGNTAVEEALYLTGIAKKVTVIHRRDK
CCCCCHHHHCCCCHHHEECCCEEEECCEEEEEECCCHHHHHHHHHHHHHHHEEEEEECCC
FRAEPILIDRLLEKQKEGVVDIKWDHVLDEVTGEESGVTGLRIKNVKTGATEDLLVQGVF
CCCCHHHHHHHHHHHHCCEEEEEHHHHHHHHCCCCCCCCEEEEECCCCCCCHHHHHEEEE
VAIGHKPNTDLFQGQLEMKDGYILTKSGLQGNATSTSVPGVFAAGDVQDNVYRQAITSAG
EEECCCCCCCHHCCEEEECCCEEEEECCCCCCCCCCCCCCEEEECCCHHHHHHHHHHHCC
TGCMAALDAQRYLESLHDKK
CCHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
STPKHAKVLILGSGPAGYTAAVYAARANLSPVLITGIAQGGQLMTTTDVENWPADAKGV
CCCCCEEEEEEECCCCCCCEEEEEHHCCCCEEEEEEECCCCEEEEECCCCCCCCCCCCC
QGPELMARFQEHAERFNTEIVFDHIHTAKLHEQPIRLIGDSGEYTCDSLIIATGASAQYL
CCHHHHHHHHHHHHHCCCEEEEECHHHHHHHCCCCEEECCCCCCEECEEEEEECCCCEEE
GLPSEEAFMGKGVSACATCDGFFYRNQEVAVIGGGNTAVEEALYLTGIAKKVTVIHRRDK
CCCCCHHHHCCCCHHHEECCCEEEECCEEEEEECCCHHHHHHHHHHHHHHHEEEEEECCC
FRAEPILIDRLLEKQKEGVVDIKWDHVLDEVTGEESGVTGLRIKNVKTGATEDLLVQGVF
CCCCHHHHHHHHHHHHCCEEEEEHHHHHHHHCCCCCCCCEEEEECCCCCCCHHHHHEEEE
VAIGHKPNTDLFQGQLEMKDGYILTKSGLQGNATSTSVPGVFAAGDVQDNVYRQAITSAG
EEECCCCCCCHHCCEEEECCCEEEEECCCCCCCCCCCCCCEEEECCCHHHHHHHHHHHCC
TGCMAALDAQRYLESLHDKK
CCHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10952301 [H]