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The map label for this gene is glpR [H]

Identifier: 116688964

GI number: 116688964

Start: 1049074

End: 1049829

Strand: Reverse

Name: glpR [H]

Synonym: Bcen2424_0941

Alternate gene names: 116688964

Gene position: 1049829-1049074 (Counterclockwise)

Preceding gene: 116688968

Following gene: 116688963

Centisome position: 30.13

GC content: 70.77

Gene sequence:

>756_bases
ATGCTGACGACACAACGCAAGAAGGCGATCCTCGATGCGCTCGCGCGCGACGGCCAGGTACTGGCCGCCGAGCTGAGCGT
GCAATTCGGCGTGTCCGAAGACACGGTGCGCCGCGACCTGCGCGAGCTCGCGGCCGAAGGGCTGCTGCAGCGCGTGCATG
GCGGCGCGCTGCCGGCGTCGCCGGCCATCGCGCCGTTCGCGCAGCGCGAAGCGCTCGAATCCGCGGAGAAGCGGCGCATC
GCGCGGCGGGCCGCGCAGATGATCGCGCCCGGGCAGGTGGCGATCGTCGACGGCGGCACGACCTCCGCGCTGCTCGTCGG
CCAGTTGCCGGCCGACCTGCGCGCGACGATCGTCACGCACAGCCCGAGCGTCGCGGTCGCGCTGGCCGCCCATCCGTCGA
TCGACGTGATCCTGATCGGCGGGCGGCTCTACAAGCATTCGATCGTCGCGGTCGGCGCCGCGGCGATGGAAGGCATCGCG
CGCATTCATGCAGACCTGTACTTCATGGGCGTCACGGGCGTCCATCCGGTAGCCGGCCTGAGCACCGGCGATTTCGAGGA
AGCGGCGATCAAGCGCGCGCTGGCCGAACGCGCGGCCGAGACGGTCGTGCTCGCGTCGCAGTCGAAACTGCGCGCGGCAT
CGCAATTCGTGATCGGTGACCTCACGCTGGCGCAGACGATCGTCGTCGAGAAGGAAACCGACGCCGCGCTGACGAAGCCG
ATCGAGGCCGCGGGCGTGACGGTGGTGCGCGCGTAG

Upstream 100 bases:

>100_bases
GCTCCCGCGTTGCAGCCATTGCAGCCTCCGGTTCGACAAAGGATGGCGCCCATGGTAACGTGCAGTTTCGTGCAATTTCA
AGAATTTTCGTGCAAACACG

Downstream 100 bases:

>100_bases
CGCGCGGGGCGCTCGCATGCGCCGAATCGGTTGCGGGCGGCACCGCGCCCGTGCCGAATCCATGTCAGCGTGCTGACAGG
CACCGCTTGCTAACATGGGC

Product: DeoR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 251; Mature: 251

Protein sequence:

>251_residues
MLTTQRKKAILDALARDGQVLAAELSVQFGVSEDTVRRDLRELAAEGLLQRVHGGALPASPAIAPFAQREALESAEKRRI
ARRAAQMIAPGQVAIVDGGTTSALLVGQLPADLRATIVTHSPSVAVALAAHPSIDVILIGGRLYKHSIVAVGAAAMEGIA
RIHADLYFMGVTGVHPVAGLSTGDFEEAAIKRALAERAAETVVLASQSKLRAASQFVIGDLTLAQTIVVEKETDAALTKP
IEAAGVTVVRA

Sequences:

>Translated_251_residues
MLTTQRKKAILDALARDGQVLAAELSVQFGVSEDTVRRDLRELAAEGLLQRVHGGALPASPAIAPFAQREALESAEKRRI
ARRAAQMIAPGQVAIVDGGTTSALLVGQLPADLRATIVTHSPSVAVALAAHPSIDVILIGGRLYKHSIVAVGAAAMEGIA
RIHADLYFMGVTGVHPVAGLSTGDFEEAAIKRALAERAAETVVLASQSKLRAASQFVIGDLTLAQTIVVEKETDAALTKP
IEAAGVTVVRA
>Mature_251_residues
MLTTQRKKAILDALARDGQVLAAELSVQFGVSEDTVRRDLRELAAEGLLQRVHGGALPASPAIAPFAQREALESAEKRRI
ARRAAQMIAPGQVAIVDGGTTSALLVGQLPADLRATIVTHSPSVAVALAAHPSIDVILIGGRLYKHSIVAVGAAAMEGIA
RIHADLYFMGVTGVHPVAGLSTGDFEEAAIKRALAERAAETVVLASQSKLRAASQFVIGDLTLAQTIVVEKETDAALTKP
IEAAGVTVVRA

Specific function: Repressor of the glycerol-3-phosphate regulon [H]

COG id: COG1349

COG function: function code KG; Transcriptional regulators of sugar metabolism

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH deoR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789829, Length=231, Percent_Identity=31.6017316017316, Blast_Score=123, Evalue=1e-29,
Organism=Escherichia coli, GI1789519, Length=251, Percent_Identity=30.2788844621514, Blast_Score=115, Evalue=3e-27,
Organism=Escherichia coli, GI1787540, Length=244, Percent_Identity=29.0983606557377, Blast_Score=98, Evalue=5e-22,
Organism=Escherichia coli, GI1788069, Length=234, Percent_Identity=29.9145299145299, Blast_Score=95, Evalue=4e-21,
Organism=Escherichia coli, GI87082344, Length=245, Percent_Identity=28.5714285714286, Blast_Score=93, Evalue=2e-20,
Organism=Escherichia coli, GI1789170, Length=230, Percent_Identity=29.1304347826087, Blast_Score=89, Evalue=2e-19,
Organism=Escherichia coli, GI1789059, Length=247, Percent_Identity=27.9352226720648, Blast_Score=89, Evalue=4e-19,
Organism=Escherichia coli, GI226510968, Length=211, Percent_Identity=29.8578199052133, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI1790635, Length=256, Percent_Identity=27.34375, Blast_Score=79, Evalue=4e-16,
Organism=Escherichia coli, GI1787063, Length=233, Percent_Identity=25.7510729613734, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1790753, Length=251, Percent_Identity=24.7011952191235, Blast_Score=71, Evalue=7e-14,

Paralogues:

None

Copy number: 900 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014036
- InterPro:   IPR001034
- InterPro:   IPR018356
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00455 DeoR; PF08220 HTH_DeoR [H]

EC number: NA

Molecular weight: Translated: 26127; Mature: 26127

Theoretical pI: Translated: 7.95; Mature: 7.95

Prosite motif: PS00894 HTH_DEOR_1 ; PS51000 HTH_DEOR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLTTQRKKAILDALARDGQVLAAELSVQFGVSEDTVRRDLRELAAEGLLQRVHGGALPAS
CCCCHHHHHHHHHHHCCCCEEEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCCCCC
PAIAPFAQREALESAEKRRIARRAAQMIAPGQVAIVDGGTTSALLVGQLPADLRATIVTH
CCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCEEEEEECCCCCCEEEEEEC
SPSVAVALAAHPSIDVILIGGRLYKHSIVAVGAAAMEGIARIHADLYFMGVTGVHPVAGL
CCCEEEEEEECCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCCCCC
STGDFEEAAIKRALAERAAETVVLASQSKLRAASQFVIGDLTLAQTIVVEKETDAALTKP
CCCCHHHHHHHHHHHHHHHHEEEEECCHHHHHHHHHHHCCHHHHHEEEEECCCCHHHHCC
IEAAGVTVVRA
HHHCCEEEEEC
>Mature Secondary Structure
MLTTQRKKAILDALARDGQVLAAELSVQFGVSEDTVRRDLRELAAEGLLQRVHGGALPAS
CCCCHHHHHHHHHHHCCCCEEEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCCCCC
PAIAPFAQREALESAEKRRIARRAAQMIAPGQVAIVDGGTTSALLVGQLPADLRATIVTH
CCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCEEEEEECCCCCCEEEEEEC
SPSVAVALAAHPSIDVILIGGRLYKHSIVAVGAAAMEGIARIHADLYFMGVTGVHPVAGL
CCCEEEEEEECCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCCCCC
STGDFEEAAIKRALAERAAETVVLASQSKLRAASQFVIGDLTLAQTIVVEKETDAALTKP
CCCCHHHHHHHHHHHHHHHHEEEEECCHHHHHHHHHHHCCHHHHHEEEEECCCCHHHHCC
IEAAGVTVVRA
HHHCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8955387; 3045764; 9278503 [H]