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The map label for this gene is hmgA [H]

Identifier: 116688843

GI number: 116688843

Start: 919540

End: 920874

Strand: Direct

Name: hmgA [H]

Synonym: Bcen2424_0820

Alternate gene names: 116688843

Gene position: 919540-920874 (Clockwise)

Preceding gene: 116688842

Following gene: 116688844

Centisome position: 26.39

GC content: 68.09

Gene sequence:

>1335_bases
ATGACGCTTGACCTGTCGAAACCGGCGACCGCCGGCTACCTGAGCGGTTTCGCGAACGAATTCGCGACCGAGGCGCTGCC
CGGTGCGCTGCCGCACGGCCGCAACTCGCCGCAGCGCGCGCCGTACGGGCTGTACGCGGAGCAGCTGTCGGGCACCGCGT
TCACCGCGCCGCGCGGCCACAACCGCCGCTCATGGCTGTACCGGATTCGCCCGGCCGCCGTGCACCGGCCGTTCGAGCCG
TATGCGGGCGCGCAGCGGCTCGTGTCGGAATTCGGCGATTCGGCCGACGTGCCGCCGACGCCGCCGAACCAGCTGCGCTG
GGACCCGCTGCCGATGCCGGTCGAGCCGACCGATTTCGTCGACGGTCTCGTGACGATGGCCGGCAACGGGTCGGCCGCCG
CGATGAACGGCTGCGCGATCCACCTGTACGCGGCGAACCGTTCGATGCAGGACCGCTTTTTCTACAGCGCGGACGGCGAG
CTGCTGATCGTGCCGCAGCAGGGGCGGCTGTTCATCGCGACCGAATTCGGCCGGCTCGACGTCGAGCCGTTCGAGATCGC
GGTGATCCCGCGCGGCGTGCGTTTTGCCGTCGCGCTGCCGGACGGCAACGCGCGCGGCTATATCTGCGAGAACTTCGGTG
CGCTGCTGCGCCTGCCGGATCTCGGCCCGATCGGCTCGAACGGGCTCGCGAACCCGCGCGATTTCCTGACGCCGCAGGCC
GCGTACGAGGATCGCGAAGGCGCGTTCGAGCTGATCGCGAAGCTGAACGGCCGGCTCTGGCGCGCGGATATCGGCCATTC
GCCGCTCGACGTCGTCGCGTGGCACGGCAACTACGCACCGTATAAGTACGATCTGCGGCTGTTCAACACGATCGGCTCGA
TCAGCTTCGACCATCCCGATCCTTCGATCTTCCTCGTGCTGCAGGCGCAGAGCGACACGCCGGGCGTCGACACGATCGAC
TTCGTGATCTTTCCGCCGCGCTGGCTCGCGGCCGAGGATACGTTCCGCCCGCCGTGGTTCCACCGCAACGTCGCGAGCGA
GTTCATGGGGCTCGTGCACGGCGCGTACGACGCGAAGGCCGAAGGCTTCGTGCCGGGCGGCGCGAGCCTGCACAACTGCA
TGTCGGGCCACGGGCCCGATGCGGACACGTTCGAGAAGGCGTCCGCGAGCGACACGACGAAGCCGCACAAGGTCGACGCG
ACGATGGCGTTCATGTTCGAAACCCGCACGCTGATTCGGCCGACGCGCTACGCGCTCGACACCGCGCAGCTGCAGGCCGA
CTACTTCGAATGCTGGCAAGGCATCAAGAAACACTTCAATCCGGAGCAACGATGA

Upstream 100 bases:

>100_bases
CTGTGCTCGGCGCTGTTCGTGCTCGGCCTTGCGGGCGTCACGCGCCGCAGCGCTGCGCAGGCGCCGAACGCCGCCCTGAA
TTGATGGAGAAAGGAAAACG

Downstream 100 bases:

>100_bases
GCGACACCCAAGACTGGCGCGCGACGCTCGACCCGGCTCGCAAGAGCTGGATCGACACGGCGAACGATCCCGCGTGCGAT
TTCCCGATCCAGAACCTGCC

Product: homogentisate 1,2-dioxygenase

Products: NA

Alternate protein names: Homogentisate oxygenase; Homogentisic acid oxidase; Homogentisicase [H]

Number of amino acids: Translated: 444; Mature: 443

Protein sequence:

>444_residues
MTLDLSKPATAGYLSGFANEFATEALPGALPHGRNSPQRAPYGLYAEQLSGTAFTAPRGHNRRSWLYRIRPAAVHRPFEP
YAGAQRLVSEFGDSADVPPTPPNQLRWDPLPMPVEPTDFVDGLVTMAGNGSAAAMNGCAIHLYAANRSMQDRFFYSADGE
LLIVPQQGRLFIATEFGRLDVEPFEIAVIPRGVRFAVALPDGNARGYICENFGALLRLPDLGPIGSNGLANPRDFLTPQA
AYEDREGAFELIAKLNGRLWRADIGHSPLDVVAWHGNYAPYKYDLRLFNTIGSISFDHPDPSIFLVLQAQSDTPGVDTID
FVIFPPRWLAAEDTFRPPWFHRNVASEFMGLVHGAYDAKAEGFVPGGASLHNCMSGHGPDADTFEKASASDTTKPHKVDA
TMAFMFETRTLIRPTRYALDTAQLQADYFECWQGIKKHFNPEQR

Sequences:

>Translated_444_residues
MTLDLSKPATAGYLSGFANEFATEALPGALPHGRNSPQRAPYGLYAEQLSGTAFTAPRGHNRRSWLYRIRPAAVHRPFEP
YAGAQRLVSEFGDSADVPPTPPNQLRWDPLPMPVEPTDFVDGLVTMAGNGSAAAMNGCAIHLYAANRSMQDRFFYSADGE
LLIVPQQGRLFIATEFGRLDVEPFEIAVIPRGVRFAVALPDGNARGYICENFGALLRLPDLGPIGSNGLANPRDFLTPQA
AYEDREGAFELIAKLNGRLWRADIGHSPLDVVAWHGNYAPYKYDLRLFNTIGSISFDHPDPSIFLVLQAQSDTPGVDTID
FVIFPPRWLAAEDTFRPPWFHRNVASEFMGLVHGAYDAKAEGFVPGGASLHNCMSGHGPDADTFEKASASDTTKPHKVDA
TMAFMFETRTLIRPTRYALDTAQLQADYFECWQGIKKHFNPEQR
>Mature_443_residues
TLDLSKPATAGYLSGFANEFATEALPGALPHGRNSPQRAPYGLYAEQLSGTAFTAPRGHNRRSWLYRIRPAAVHRPFEPY
AGAQRLVSEFGDSADVPPTPPNQLRWDPLPMPVEPTDFVDGLVTMAGNGSAAAMNGCAIHLYAANRSMQDRFFYSADGEL
LIVPQQGRLFIATEFGRLDVEPFEIAVIPRGVRFAVALPDGNARGYICENFGALLRLPDLGPIGSNGLANPRDFLTPQAA
YEDREGAFELIAKLNGRLWRADIGHSPLDVVAWHGNYAPYKYDLRLFNTIGSISFDHPDPSIFLVLQAQSDTPGVDTIDF
VIFPPRWLAAEDTFRPPWFHRNVASEFMGLVHGAYDAKAEGFVPGGASLHNCMSGHGPDADTFEKASASDTTKPHKVDAT
MAFMFETRTLIRPTRYALDTAQLQADYFECWQGIKKHFNPEQR

Specific function: Unknown

COG id: COG3508

COG function: function code Q; Homogentisate 1,2-dioxygenase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the homogentisate dioxygenase family [H]

Homologues:

Organism=Homo sapiens, GI115527117, Length=444, Percent_Identity=52.9279279279279, Blast_Score=466, Evalue=1e-131,
Organism=Caenorhabditis elegans, GI17507969, Length=432, Percent_Identity=54.8611111111111, Blast_Score=459, Evalue=1e-129,
Organism=Drosophila melanogaster, GI24583650, Length=434, Percent_Identity=52.7649769585253, Blast_Score=447, Evalue=1e-126,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011051
- InterPro:   IPR005708
- InterPro:   IPR022950 [H]

Pfam domain/function: PF04209 HgmA [H]

EC number: =1.13.11.5 [H]

Molecular weight: Translated: 48961; Mature: 48829

Theoretical pI: Translated: 5.90; Mature: 5.90

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLDLSKPATAGYLSGFANEFATEALPGALPHGRNSPQRAPYGLYAEQLSGTAFTAPRGH
CEECCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHCCCCEEECCCCC
NRRSWLYRIRPAAVHRPFEPYAGAQRLVSEFGDSADVPPTPPNQLRWDPLPMPVEPTDFV
CCCCEEEEECHHHHCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCHHHH
DGLVTMAGNGSAAAMNGCAIHLYAANRSMQDRFFYSADGELLIVPQQGRLFIATEFGRLD
HHHEEECCCCCCEEECCCEEEEEECCCCCCCCEEEECCCCEEEEECCCCEEEEEECCCCC
VEPFEIAVIPRGVRFAVALPDGNARGYICENFGALLRLPDLGPIGSNGLANPRDFLTPQA
CCCEEEEEECCCEEEEEECCCCCCCEEEECCCCCEEECCCCCCCCCCCCCCCHHHCCCCH
AYEDREGAFELIAKLNGRLWRADIGHSPLDVVAWHGNYAPYKYDLRLFNTIGSISFDHPD
HCCCCCHHHHHHHHHCCEEEEECCCCCCCEEEEECCCCCCEEEEEEEEECCCCCEECCCC
PSIFLVLQAQSDTPGVDTIDFVIFPPRWLAAEDTFRPPWFHRNVASEFMGLVHGAYDAKA
CEEEEEEEECCCCCCCCEEEEEEECCCEECCCCCCCCCCHHHHHHHHHHHHHHCCCCCCC
EGFVPGGASLHNCMSGHGPDADTFEKASASDTTKPHKVDATMAFMFETRTLIRPTRYALD
CCCCCCCCHHHHHHCCCCCCHHHHHCCCCCCCCCCCCCCCEEEEEEHHHHHHCCHHHHHH
TAQLQADYFECWQGIKKHFNPEQR
HHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
TLDLSKPATAGYLSGFANEFATEALPGALPHGRNSPQRAPYGLYAEQLSGTAFTAPRGH
EECCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHCCCCEEECCCCC
NRRSWLYRIRPAAVHRPFEPYAGAQRLVSEFGDSADVPPTPPNQLRWDPLPMPVEPTDFV
CCCCEEEEECHHHHCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCHHHH
DGLVTMAGNGSAAAMNGCAIHLYAANRSMQDRFFYSADGELLIVPQQGRLFIATEFGRLD
HHHEEECCCCCCEEECCCEEEEEECCCCCCCCEEEECCCCEEEEECCCCEEEEEECCCCC
VEPFEIAVIPRGVRFAVALPDGNARGYICENFGALLRLPDLGPIGSNGLANPRDFLTPQA
CCCEEEEEECCCEEEEEECCCCCCCEEEECCCCCEEECCCCCCCCCCCCCCCHHHCCCCH
AYEDREGAFELIAKLNGRLWRADIGHSPLDVVAWHGNYAPYKYDLRLFNTIGSISFDHPD
HCCCCCHHHHHHHHHCCEEEEECCCCCCCEEEEECCCCCCEEEEEEEEECCCCCEECCCC
PSIFLVLQAQSDTPGVDTIDFVIFPPRWLAAEDTFRPPWFHRNVASEFMGLVHGAYDAKA
CEEEEEEEECCCCCCCCEEEEEEECCCEECCCCCCCCCCHHHHHHHHHHHHHHCCCCCCC
EGFVPGGASLHNCMSGHGPDADTFEKASASDTTKPHKVDATMAFMFETRTLIRPTRYALD
CCCCCCCCHHHHHHCCCCCCHHHHHCCCCCCCCCCCCCCCEEEEEEHHHHHHCCHHHHHH
TAQLQADYFECWQGIKKHFNPEQR
HHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA