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The map label for this gene is ychE [H]

Identifier: 116688452

GI number: 116688452

Start: 478134

End: 478754

Strand: Direct

Name: ychE [H]

Synonym: Bcen2424_0428

Alternate gene names: 116688452

Gene position: 478134-478754 (Clockwise)

Preceding gene: 116688451

Following gene: 116688453

Centisome position: 13.72

GC content: 63.12

Gene sequence:

>621_bases
ATGGATCTGCTCAAATCGTTCATTTCGCTGCTCGCGCTGATCAACCCGGTCGGCGCGGTGCCGTTTTTCCTGAGCCTGAC
GGCGCAGCAGACGGACGACGAGCGGCGGCGCACGATCCGGATCGCATCGGTGTCGGTGTTCTGCGTGATGACGGTGACCG
CGCTGCTCGGGCAGCAGATCATCAACTTCTTCGGCATTTCGGTCGGGTCGCTCGAAGTGGGCGGCGGGATCATCATGCTG
CTGATGGCGATCAACATGCTGAACGCGCAGATCGGCAACACGCGATCGACGCCGGAGGAACGCCACGAAGCCGAGCTGAA
GGACAACATCGCGGTCGTGCCGCTGGCGATTCCGCTGCTCACGGGCCCCGGCTCGATCAGCACGGTGATCATCTATGCGG
CGAACGCGCATCACTGGTATGAACGGGCCGGGCTGGTCGCGATCGGCGCGGTCCTGGCTTTTCTGTGTTTCGTCGCGATG
CGGCTCGCCGAGCCGATCGCGAACTGGATCGGCCGCACCGGCATCAACATCGCCACACGGCTGATGGGTCTGATGCTGTC
GGCGCTGGCGGTGGAATTCATCGTCAATGGACTGAGGGCGCTACTGCCTGCACTGAGATGA

Upstream 100 bases:

>100_bases
GGCGGCGGGGCAGATTCCGTCGACGAAAGGCAGCCTCTAACTTCCGAACGGACGACGCCAAGGACGACCTCACGGCTTCG
GCGCGGCGCGCCGGCGTGCG

Downstream 100 bases:

>100_bases
AAACTTCGATTGCGATTGTGGATTATGGGATGGGCAACCTGCGCTCGGTCGCGCAGGCGCTCAAGAAGGCCGAACCGGCC
GCCGACGTGGCGATCGTCGA

Product: multiple antibiotic resistance (MarC)-related proteins

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 206; Mature: 206

Protein sequence:

>206_residues
MDLLKSFISLLALINPVGAVPFFLSLTAQQTDDERRRTIRIASVSVFCVMTVTALLGQQIINFFGISVGSLEVGGGIIML
LMAINMLNAQIGNTRSTPEERHEAELKDNIAVVPLAIPLLTGPGSISTVIIYAANAHHWYERAGLVAIGAVLAFLCFVAM
RLAEPIANWIGRTGINIATRLMGLMLSALAVEFIVNGLRALLPALR

Sequences:

>Translated_206_residues
MDLLKSFISLLALINPVGAVPFFLSLTAQQTDDERRRTIRIASVSVFCVMTVTALLGQQIINFFGISVGSLEVGGGIIML
LMAINMLNAQIGNTRSTPEERHEAELKDNIAVVPLAIPLLTGPGSISTVIIYAANAHHWYERAGLVAIGAVLAFLCFVAM
RLAEPIANWIGRTGINIATRLMGLMLSALAVEFIVNGLRALLPALR
>Mature_206_residues
MDLLKSFISLLALINPVGAVPFFLSLTAQQTDDERRRTIRIASVSVFCVMTVTALLGQQIINFFGISVGSLEVGGGIIML
LMAINMLNAQIGNTRSTPEERHEAELKDNIAVVPLAIPLLTGPGSISTVIIYAANAHHWYERAGLVAIGAVLAFLCFVAM
RLAEPIANWIGRTGINIATRLMGLMLSALAVEFIVNGLRALLPALR

Specific function: Unknown

COG id: COG2095

COG function: function code U; Multiple antibiotic transporter

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UPF0056 (marC) family [H]

Homologues:

Organism=Escherichia coli, GI1787494, Length=202, Percent_Identity=38.1188118811881, Blast_Score=161, Evalue=4e-41,
Organism=Escherichia coli, GI1787809, Length=194, Percent_Identity=34.020618556701, Blast_Score=103, Evalue=1e-23,
Organism=Escherichia coli, GI1789842, Length=201, Percent_Identity=28.3582089552239, Blast_Score=84, Evalue=5e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002771 [H]

Pfam domain/function: PF01914 MarC [H]

EC number: NA

Molecular weight: Translated: 22138; Mature: 22138

Theoretical pI: Translated: 8.25; Mature: 8.25

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDLLKSFISLLALINPVGAVPFFLSLTAQQTDDERRRTIRIASVSVFCVMTVTALLGQQI
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
INFFGISVGSLEVGGGIIMLLMAINMLNAQIGNTRSTPEERHEAELKDNIAVVPLAIPLL
HHHHCCCCCCEECCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCEEEEEHHHHHC
TGPGSISTVIIYAANAHHWYERAGLVAIGAVLAFLCFVAMRLAEPIANWIGRTGINIATR
CCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
LMGLMLSALAVEFIVNGLRALLPALR
HHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MDLLKSFISLLALINPVGAVPFFLSLTAQQTDDERRRTIRIASVSVFCVMTVTALLGQQI
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
INFFGISVGSLEVGGGIIMLLMAINMLNAQIGNTRSTPEERHEAELKDNIAVVPLAIPLL
HHHHCCCCCCEECCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCEEEEEHHHHHC
TGPGSISTVIIYAANAHHWYERAGLVAIGAVLAFLCFVAMRLAEPIANWIGRTGINIATR
CCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
LMGLMLSALAVEFIVNGLRALLPALR
HHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 2015910; 9097039; 9278503 [H]