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The map label for this gene is ybdL [H]

Identifier: 116688143

GI number: 116688143

Start: 128154

End: 129308

Strand: Direct

Name: ybdL [H]

Synonym: Bcen2424_0119

Alternate gene names: 116688143

Gene position: 128154-129308 (Clockwise)

Preceding gene: 116688142

Following gene: 116688144

Centisome position: 3.68

GC content: 67.27

Gene sequence:

>1155_bases
ATGCGAAGCGCCACCGCGCCCCGTTCGAAACTGCCCGACGTCGGGACGACGATCTTCACGGTGATCGGCCAACTGGCTGC
TCAACACGACGCGCTGAACCTGTCGCAGGGCGCGCCGAATTTCGCGCCCGATCCGGCGCTCGTCGAAGGCGTCGCGCGCG
CGATGCGCGACGGTCACAACCAGTACGCGCCGATGGCCGGCGTGATCGCGCTGCGCGAGCGGCTCGCCGAGAAGACCGAG
GCGCTGTACGGCGCGCGCTACGACCCGGCGACCGAAATCACGGTGATCGCGAGCGCGAGCGAAGGGCTTTACGCGGCGAT
CAGCGCGCTCGTGCATCCCGGCGACGAAGTGATCTATTTCGAGCCGTCGTTCGACAGCTATGCGCCGATCGTGCGACTGC
AGGGCGCGACGCCGGTCGCGATCAAGCTGTCGCCCGAGCATTTCCGCGTGAACTGGGACGAGGTGGCCGCGGCCATCACG
CCGCGCACGCGGATGATCATCGTCAACACGCCGCACAACCCGACCGCGACGGTGTTCTCCGCCGACGATCTCGAACGCCT
CGCGCAACTCACGCGCGACACGGGCATCGTCGTGCTGTCCGACGAAGTCTACGAGCACGTCGTGTTCGACGGCGCGCAGC
ACCAGAGCGTCGCGCGCCATCGCGAGCTGGCCGAGCGCAGCGTGATCGTGTCGTCGTTCGGCAAGTCGTTCCACGTGACC
GGCTGGCGCGTCGGCCATTGCCTCGCGCCGGCCGAGCTGATGGACGAGATCCGCAAGGTGCACCAGTTCATGGTGTTCTC
GGCCGACACGCCGATGCAGGTCGCGTTCGCGGAGATCCTCGCGCGGCCGGACAGCTATCTCGGCCTGTCGGCGTTCTACC
AGGCCAAGCGCGACCTGCTCGCGCGCGAGCTGGCCGATTCGCGTTTCGAGCTGCTGCCGAGCGAAGGCTCGTTCTTCATG
CTCGCGCGCTTTCGCCACTTCTCGGACGAAAGCGACAGCGATTTCGTGCTGCGTCTGATCCGCGATGCGCGTGTCGCGAC
GATTCCGCTGTCGGCGTTCTATACCGACGGCACCGACGCCGGCGTGATCCGGCTCAGTTTTTCGAAGGACGACGCGACGC
TGGTCGAAGGCGCGCGGCGGCTGCGTTCGCTGTAA

Upstream 100 bases:

>100_bases
AACTTTCGATTGTCCGCCGATATTGGCTCGGGCTAAATCATGCGGCAGATGCAGGCCGCGCACGGCGCGGCCCGCCCGAA
GGACATCAGGAGGAGAAGTC

Downstream 100 bases:

>100_bases
GGCCCATACGGAAACCGGCGACGGAGACGTCGCATCGACCAGACCCAGGAGATCACGATGAAACACACGGCTACCTTGAA
ACTCGCGTTCGCACTCGCGT

Product: putative aminotransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 384; Mature: 384

Protein sequence:

>384_residues
MRSATAPRSKLPDVGTTIFTVIGQLAAQHDALNLSQGAPNFAPDPALVEGVARAMRDGHNQYAPMAGVIALRERLAEKTE
ALYGARYDPATEITVIASASEGLYAAISALVHPGDEVIYFEPSFDSYAPIVRLQGATPVAIKLSPEHFRVNWDEVAAAIT
PRTRMIIVNTPHNPTATVFSADDLERLAQLTRDTGIVVLSDEVYEHVVFDGAQHQSVARHRELAERSVIVSSFGKSFHVT
GWRVGHCLAPAELMDEIRKVHQFMVFSADTPMQVAFAEILARPDSYLGLSAFYQAKRDLLARELADSRFELLPSEGSFFM
LARFRHFSDESDSDFVLRLIRDARVATIPLSAFYTDGTDAGVIRLSFSKDDATLVEGARRLRSL

Sequences:

>Translated_384_residues
MRSATAPRSKLPDVGTTIFTVIGQLAAQHDALNLSQGAPNFAPDPALVEGVARAMRDGHNQYAPMAGVIALRERLAEKTE
ALYGARYDPATEITVIASASEGLYAAISALVHPGDEVIYFEPSFDSYAPIVRLQGATPVAIKLSPEHFRVNWDEVAAAIT
PRTRMIIVNTPHNPTATVFSADDLERLAQLTRDTGIVVLSDEVYEHVVFDGAQHQSVARHRELAERSVIVSSFGKSFHVT
GWRVGHCLAPAELMDEIRKVHQFMVFSADTPMQVAFAEILARPDSYLGLSAFYQAKRDLLARELADSRFELLPSEGSFFM
LARFRHFSDESDSDFVLRLIRDARVATIPLSAFYTDGTDAGVIRLSFSKDDATLVEGARRLRSL
>Mature_384_residues
MRSATAPRSKLPDVGTTIFTVIGQLAAQHDALNLSQGAPNFAPDPALVEGVARAMRDGHNQYAPMAGVIALRERLAEKTE
ALYGARYDPATEITVIASASEGLYAAISALVHPGDEVIYFEPSFDSYAPIVRLQGATPVAIKLSPEHFRVNWDEVAAAIT
PRTRMIIVNTPHNPTATVFSADDLERLAQLTRDTGIVVLSDEVYEHVVFDGAQHQSVARHRELAERSVIVSSFGKSFHVT
GWRVGHCLAPAELMDEIRKVHQFMVFSADTPMQVAFAEILARPDSYLGLSAFYQAKRDLLARELADSRFELLPSEGSFFM
LARFRHFSDESDSDFVLRLIRDARVATIPLSAFYTDGTDAGVIRLSFSKDDATLVEGARRLRSL

Specific function: Shows aminotransferase activity with methionine and histidine as substrates, and to a lesser extent also with phenylalanine [H]

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI95147551, Length=395, Percent_Identity=34.6835443037975, Blast_Score=213, Evalue=3e-55,
Organism=Homo sapiens, GI169881279, Length=395, Percent_Identity=34.6835443037975, Blast_Score=213, Evalue=3e-55,
Organism=Homo sapiens, GI56713254, Length=390, Percent_Identity=30.5128205128205, Blast_Score=195, Evalue=7e-50,
Organism=Homo sapiens, GI56713256, Length=390, Percent_Identity=30.5128205128205, Blast_Score=194, Evalue=8e-50,
Organism=Homo sapiens, GI169881281, Length=393, Percent_Identity=30.5343511450382, Blast_Score=166, Evalue=3e-41,
Organism=Homo sapiens, GI4507369, Length=374, Percent_Identity=25.1336898395722, Blast_Score=106, Evalue=3e-23,
Organism=Escherichia coli, GI1786816, Length=379, Percent_Identity=51.7150395778364, Blast_Score=387, Evalue=1e-109,
Organism=Escherichia coli, GI1788722, Length=362, Percent_Identity=23.7569060773481, Blast_Score=103, Evalue=3e-23,
Organism=Escherichia coli, GI1788627, Length=342, Percent_Identity=26.3157894736842, Blast_Score=88, Evalue=1e-18,
Organism=Escherichia coli, GI1788332, Length=262, Percent_Identity=25.5725190839695, Blast_Score=67, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI71994472, Length=422, Percent_Identity=32.4644549763033, Blast_Score=221, Evalue=6e-58,
Organism=Caenorhabditis elegans, GI71994476, Length=422, Percent_Identity=32.4644549763033, Blast_Score=221, Evalue=7e-58,
Organism=Caenorhabditis elegans, GI17567369, Length=419, Percent_Identity=29.3556085918854, Blast_Score=197, Evalue=6e-51,
Organism=Caenorhabditis elegans, GI17567663, Length=350, Percent_Identity=25.7142857142857, Blast_Score=106, Evalue=2e-23,
Organism=Saccharomyces cerevisiae, GI6322401, Length=390, Percent_Identity=29.2307692307692, Blast_Score=170, Evalue=3e-43,
Organism=Drosophila melanogaster, GI28573069, Length=392, Percent_Identity=33.6734693877551, Blast_Score=208, Evalue=5e-54,
Organism=Drosophila melanogaster, GI24646114, Length=392, Percent_Identity=33.6734693877551, Blast_Score=208, Evalue=5e-54,
Organism=Drosophila melanogaster, GI28573067, Length=392, Percent_Identity=33.6734693877551, Blast_Score=208, Evalue=5e-54,
Organism=Drosophila melanogaster, GI28573065, Length=392, Percent_Identity=33.6734693877551, Blast_Score=208, Evalue=5e-54,
Organism=Drosophila melanogaster, GI18859735, Length=356, Percent_Identity=25.2808988764045, Blast_Score=92, Evalue=7e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: 2.6.1.- [C]

Molecular weight: Translated: 42247; Mature: 42247

Theoretical pI: Translated: 5.76; Mature: 5.76

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRSATAPRSKLPDVGTTIFTVIGQLAAQHDALNLSQGAPNFAPDPALVEGVARAMRDGHN
CCCCCCCHHCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCC
QYAPMAGVIALRERLAEKTEALYGARYDPATEITVIASASEGLYAAISALVHPGDEVIYF
CCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEECCCCHHHHHHHHHCCCCCEEEE
EPSFDSYAPIVRLQGATPVAIKLSPEHFRVNWDEVAAAITPRTRMIIVNTPHNPTATVFS
CCCCCCCCCEEEECCCCEEEEEECCCCEECCHHHHHHHCCCCEEEEEEECCCCCCEEEEE
ADDLERLAQLTRDTGIVVLSDEVYEHVVFDGAQHQSVARHRELAERSVIVSSFGKSFHVT
HHHHHHHHHHHHCCCEEEECHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEC
GWRVGHCLAPAELMDEIRKVHQFMVFSADTPMQVAFAEILARPDSYLGLSAFYQAKRDLL
CEEHHHHCCCHHHHHHHHHHHHHEEECCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHH
ARELADSRFELLPSEGSFFMLARFRHFSDESDSDFVLRLIRDARVATIPLSAFYTDGTDA
HHHHHCCHHHCCCCCCCEEEEEHHHHCCCCCCHHHHHHHHHCCCEEEEEEEEEECCCCCC
GVIRLSFSKDDATLVEGARRLRSL
EEEEEEECCCCHHHHHHHHHHHCC
>Mature Secondary Structure
MRSATAPRSKLPDVGTTIFTVIGQLAAQHDALNLSQGAPNFAPDPALVEGVARAMRDGHN
CCCCCCCHHCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCC
QYAPMAGVIALRERLAEKTEALYGARYDPATEITVIASASEGLYAAISALVHPGDEVIYF
CCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEECCCCHHHHHHHHHCCCCCEEEE
EPSFDSYAPIVRLQGATPVAIKLSPEHFRVNWDEVAAAITPRTRMIIVNTPHNPTATVFS
CCCCCCCCCEEEECCCCEEEEEECCCCEECCHHHHHHHCCCCEEEEEEECCCCCCEEEEE
ADDLERLAQLTRDTGIVVLSDEVYEHVVFDGAQHQSVARHRELAERSVIVSSFGKSFHVT
HHHHHHHHHHHHCCCEEEECHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEC
GWRVGHCLAPAELMDEIRKVHQFMVFSADTPMQVAFAEILARPDSYLGLSAFYQAKRDLL
CEEHHHHCCCHHHHHHHHHHHHHEEECCCCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHH
ARELADSRFELLPSEGSFFMLARFRHFSDESDSDFVLRLIRDARVATIPLSAFYTDGTDA
HHHHHCCHHHCCCCCCCEEEEEHHHHCCCCCCHHHHHHHHHCCCEEEEEEEEEECCCCCC
GVIRLSFSKDDATLVEGARRLRSL
EEEEEEECCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: Pyridoxal Phosphate. [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8905232; 9278503 [H]