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The map label for this gene is putA [H]

Identifier: 116688137

GI number: 116688137

Start: 117943

End: 121875

Strand: Direct

Name: putA [H]

Synonym: Bcen2424_0113

Alternate gene names: 116688137

Gene position: 117943-121875 (Clockwise)

Preceding gene: 116688136

Following gene: 116688138

Centisome position: 3.39

GC content: 69.97

Gene sequence:

>3933_bases
ATGGCAAGCACGACTCTCGGCGTCAAAGTCGACGACCTTCTCCGCTCGCGCCTGAAAGACGCGGCGGCGCGTCTCGAGCG
CACTCCCCACTGGCTGATCAAGCAGGCGATCTTCGCGTATCTCGAGCGGATCGAGCACGGCCAGCTGCCGCCCGAGCTGT
CGGGCCACAGCGGCGTGACGGAGCTCGCCGACGGTCAGGCAACGGACGGCGACGACGACAACTCGCCGCATCCGTTCCTC
GAGTTCGCGCAGAACGTGCAGCCGCAATCGGTGCTGCGCGCGGCGATCACGGCCGCGTACCGCCGTCCGGAGCCGGAGTG
CGTGCCGTTCCTGCTCGGCCAGGCGCGCCTGCCCGCGAACCTGCAGGCGGACGTGCAGGCGCTCGCGACGAAGCTGGTCG
AGGCGCTGCGCGAGAAGAGCTCGGGCGGCGGCGTCGAAGGGCTGATCCACGAGTTCTCGCTGTCGAGCCAGGAAGGCGTC
GCGCTGATGTGCCTCGCCGAAGCGCTGCTGCGCATTCCCGATCGCGCGACGCGCGATGCGCTGATCCGCGACAAGATCAG
CAAGGGCGACTGGCGCTCGCACGTCGGCCACGCGCCATCGCTGTTCGTGAACGCGGCGACCTGGGGGCTGATGATCACCG
GCAAGCTCGTGACGACCAACAGCGAAGCGGGCCTGTCGTCGGCGCTCACGCGCCTGATCGGCCGCGGCGGCGAGCCGCTG
ATCCGCAAGGGCGTCGACATGGCGATGCGCCTGATGGGCGAGCAGTTCGTCACCGGCGAAACGATTTCCGAAGCGCTCGC
GAACAGCCGCAAGTACGAAGCGCGCGGCTTTCGCTACTCGTACGACATGCTCGGCGAAGCGGCGACGACCGAAGAGGACG
CACAGCGCTACTACGCGTCGTACGAACAGGCGATCCACGCGATCGGCAAGGCGGCCGGCGGCCGCGGCATCTACGAAGGC
CCGGGCATCTCGATCAAGCTGTCGGCGCTGCATGCGCGCTACTCGCGTTCGCAGCAGGACCGCACGATGAGCGAGCTGCT
GCCGCGCGTGCGTGCGCTGGCGCTGCTCGCGCGCCGCTACGACATCGGCCTGAACATCGACGCGGAAGAGGCCGACCGTC
TCGAACTGTCGCTCGACCTGCTCGAGGCGCTGTGCTTCGATCCGGAGCTCGCGGGCTGGAACGGCATCGGCTTCGTCGTG
CAGGGCTACCAGAAGCGCTGCCCGTTCGTGATCGACTACCTGATCGATCTCGCGCGCCGCAGCCGTCACCGCCTGATGAT
CCGCCTCGTGAAGGGCGCGTACTGGGACAGCGAGATCAAGCGGGCGCAGGTCGACGGCCTCGAAGGCTATCCGGTCTACA
CGCGCAAGATCTACACCGACGTGTCGTACCTCGCGTGCGCGAAGAAGCTGCTCGGAGCGCCGGACGCCGTCTACCCGCAA
TTCGCGACGCACAACGCGCACACGCTGGCCGCGATCTATCACCTGGCCGGCCAGAACTACTACCCGGGCCAGTACGAATT
CCAGTGCCTGCACGGGATGGGCGAGCCGCTCTACGAGGAAGTCACGGGCCGCGACAAGCTGAATCGTCCGTGCCGCGTGT
ACGCACCGGTCGGCACGCACGAGACGCTGCTCGCGTATCTCGTGCGCCGTTTGCTGGAAAACGGCGCGAACACGTCGTTC
GTGAACCGCATTGCGGATAAAACCGTGCCGGTGAAGGAGCTGGTCGCCGATCCGGTCGACGAAGCGTCGAAGGTCGTGCC
GCTCGGCGCGCCGCACGCGAAGATCCCGCTGCCGCGCAACCTGTACGGCGACGAGCGTCCCAACTCGATGGGCCTCGACC
TGTCGAACGAACATCGTCTCGCGTCGCTGTCGTCCGCGCTGCTCGCGAGCGCGCACCACCCGTGGCGCGCGGCGCCGATG
CTCGCCGACGACGCGCTCGCCGACGCGCCGGCGCGCGACGTGCGCAACCCGGCCGACCAGCGCGACGTGGTCGGCACGGT
CAGCGAAGCGACGTCCGAGCACGTGAGCGCGGCGCTCGCGCATGCGGTGGCCGCCGCGCCGATCTGGCAGGCGACGCCGG
TCGACGCACGCGCCGATTGCCTGGTGCGCGCCGCTGACCTCCTCGAAGCGCAGATGCACACGCTGATGGGCCTGATCGTG
CGCGAAGCCGGCAAGTCGCTGCCGAACGCGATCGCCGAAATCCGCGAAGCGGTCGACTTCCTGCGCTATTACGCGGCGCA
GATCCGCGGCGAATTCTCGAACGACACGCACCGTCCGCTCGGCCCCGTGGTCTGTATCAGCCCGTGGAACTTCCCGCTCG
CGATCTTCATGGGCCAGGTGGCCGCGGCGCTCGCCGCCGGCAACACGGTGCTCGCGAAGCCGGCCGAACAGACGCCGCTG
ATCGCCGCGCAGGCCGTGCGCCTCTTGCGCGAGGCCGGCGTGCCGGCCGGCGCGGTGCAACTGCTGCCGGGCACCGGCGA
GACCGTCGGCGCGGCGCTGGTCGCCGATCCGCGCACCCGGGCGGTGATGTTCACCGGTTCGACCGAAGTCGCGCGCCTGA
TCAACAAGACGCTCGCCGCGCGCCTCGACCCGGACGGCAAGCCGATTCCGCTGATCGCCGAAACGGGCGGCCAGAACGCG
ATGATCGTCGACTCGTCGGCGCTCGCGGAGCAGGTCGTCGCGGACGTGATGCAGTCGTCGTTCGACTCGGCCGGTCAACG
GTGTTCGGCGCTGCGCGTTCTGTGTCTGCAGGACGACGTCGCGGACCGCACGCTGACGATGCTCAAGGGCGCGATGCACG
AGCTGGCGCTCGGCAACCCGGACCGGCTGTCGACCGACGTTGGCCCGGTGATCGACGCCGAAGCGAAGCAGACGATCGAC
ACGCACGTCGCGGCGATGAAGGACAAGGGCCACGCGGTCACGCAACTGCCGATGCCCGACGCGTGCGCGCACGGCACGTT
CGTGCCGCCGACGCTGATCGAGATCGGCAGCATCGACGAGCTGAAGCGTGAAGTGTTCGGCCCCGTGCTGCACGTGGTGC
GCTACCGCCGCAGCCAGCTCGACAAGCTGCTCGAGCAGATCCGCGCGACCGGCTACGGGCTGACGCTCGGCATTCACACG
CGGATCGACGAGACGATCGCGCACGTGATCTCGAATGCGCACGTGGGCAACATCTACGTGAACCGCAACGTGATCGGCGC
GGTGGTCGGCGTGCAGCCGTTCGGCGGCGAAGGGCTGTCGGGCACGGGCCCGAAGGCCGGCGGCGCGCTGTACCTGCAGC
GCCTGCTCGCGACGCGTCCGTCGGGCCTGCCGCGCGCGCTCGCGCAGTCGCTGGTGGCGGACGGCGCGACCGAAAGCGAT
GCGCGCGGCAACCCGGCGGCGGCGCTCACGACGCTGCGCGACTGGCTGATCGAGCAGCGCGAGCCGGCGCTGGCCGCGCG
TTGCGACGGCTACCTCGCGCAGGTGCCGGCCGGCGCGACCGCGGTGCTGAGCGGTCCGACGGGCGAGCGAAACACGTATA
CACTCGGCCCGCGCGGCACGGTGCTGTGTGTCGCGGCGACGCCCGGCGGCGCGCGTGCGCAGTTCGCGGCGGTGCTGGCG
ACGGGCAACCGTGCGTTGTTCGCCGGCGCGGCGGGCGAGGCGCTGGTCGCCGCGCTGCCGGCGTCGCTGAAGGCGCACGC
GGCCGTGCGCAAGCAGGCCGACGCGCCGTTCGACGCGGTGCTGTTCGAAGGCGACAGCGACGAACTGCAGACGCTCGTGA
AGGACGTCGCGCAGCGGCCGGGCCCGATCGTGTCGGTGCAGGGCGTGTCGGCGGGCGCGTTCGAGAACGGCGATGCGGAA
GACTACGCGCTCGAGCGGCTGCTGACGGAACGCTCGGTGAGCGTGAATACGGCCGCGGCGGGCGGCAATGCGAATTTGAT
GACGATCGGCTGA

Upstream 100 bases:

>100_bases
CTATCTCTCAATTTGGTTGCACCTTTTTATTGCGTGCCGTAGGATTTCGCGCATCCTCTTACACCACATTGCCGGCCTCG
CACCGGCGCACGAACCCACC

Downstream 100 bases:

>100_bases
TCATCCTTGCCGTTCGGATCAAACAAAGGAAGCGGCCAGGCGATCCCGAAGCCGCTCCATTTACCCTGGTACCAAGGAGA
TGCTATGCAACACACGATGA

Product: trifunctional transcriptional regulator/proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase

Products: NA

Alternate protein names: Proline dehydrogenase; Proline oxidase; Delta-1-pyrroline-5-carboxylate dehydrogenase; P5C dehydrogenase [H]

Number of amino acids: Translated: 1310; Mature: 1309

Protein sequence:

>1310_residues
MASTTLGVKVDDLLRSRLKDAAARLERTPHWLIKQAIFAYLERIEHGQLPPELSGHSGVTELADGQATDGDDDNSPHPFL
EFAQNVQPQSVLRAAITAAYRRPEPECVPFLLGQARLPANLQADVQALATKLVEALREKSSGGGVEGLIHEFSLSSQEGV
ALMCLAEALLRIPDRATRDALIRDKISKGDWRSHVGHAPSLFVNAATWGLMITGKLVTTNSEAGLSSALTRLIGRGGEPL
IRKGVDMAMRLMGEQFVTGETISEALANSRKYEARGFRYSYDMLGEAATTEEDAQRYYASYEQAIHAIGKAAGGRGIYEG
PGISIKLSALHARYSRSQQDRTMSELLPRVRALALLARRYDIGLNIDAEEADRLELSLDLLEALCFDPELAGWNGIGFVV
QGYQKRCPFVIDYLIDLARRSRHRLMIRLVKGAYWDSEIKRAQVDGLEGYPVYTRKIYTDVSYLACAKKLLGAPDAVYPQ
FATHNAHTLAAIYHLAGQNYYPGQYEFQCLHGMGEPLYEEVTGRDKLNRPCRVYAPVGTHETLLAYLVRRLLENGANTSF
VNRIADKTVPVKELVADPVDEASKVVPLGAPHAKIPLPRNLYGDERPNSMGLDLSNEHRLASLSSALLASAHHPWRAAPM
LADDALADAPARDVRNPADQRDVVGTVSEATSEHVSAALAHAVAAAPIWQATPVDARADCLVRAADLLEAQMHTLMGLIV
REAGKSLPNAIAEIREAVDFLRYYAAQIRGEFSNDTHRPLGPVVCISPWNFPLAIFMGQVAAALAAGNTVLAKPAEQTPL
IAAQAVRLLREAGVPAGAVQLLPGTGETVGAALVADPRTRAVMFTGSTEVARLINKTLAARLDPDGKPIPLIAETGGQNA
MIVDSSALAEQVVADVMQSSFDSAGQRCSALRVLCLQDDVADRTLTMLKGAMHELALGNPDRLSTDVGPVIDAEAKQTID
THVAAMKDKGHAVTQLPMPDACAHGTFVPPTLIEIGSIDELKREVFGPVLHVVRYRRSQLDKLLEQIRATGYGLTLGIHT
RIDETIAHVISNAHVGNIYVNRNVIGAVVGVQPFGGEGLSGTGPKAGGALYLQRLLATRPSGLPRALAQSLVADGATESD
ARGNPAAALTTLRDWLIEQREPALAARCDGYLAQVPAGATAVLSGPTGERNTYTLGPRGTVLCVAATPGGARAQFAAVLA
TGNRALFAGAAGEALVAALPASLKAHAAVRKQADAPFDAVLFEGDSDELQTLVKDVAQRPGPIVSVQGVSAGAFENGDAE
DYALERLLTERSVSVNTAAAGGNANLMTIG

Sequences:

>Translated_1310_residues
MASTTLGVKVDDLLRSRLKDAAARLERTPHWLIKQAIFAYLERIEHGQLPPELSGHSGVTELADGQATDGDDDNSPHPFL
EFAQNVQPQSVLRAAITAAYRRPEPECVPFLLGQARLPANLQADVQALATKLVEALREKSSGGGVEGLIHEFSLSSQEGV
ALMCLAEALLRIPDRATRDALIRDKISKGDWRSHVGHAPSLFVNAATWGLMITGKLVTTNSEAGLSSALTRLIGRGGEPL
IRKGVDMAMRLMGEQFVTGETISEALANSRKYEARGFRYSYDMLGEAATTEEDAQRYYASYEQAIHAIGKAAGGRGIYEG
PGISIKLSALHARYSRSQQDRTMSELLPRVRALALLARRYDIGLNIDAEEADRLELSLDLLEALCFDPELAGWNGIGFVV
QGYQKRCPFVIDYLIDLARRSRHRLMIRLVKGAYWDSEIKRAQVDGLEGYPVYTRKIYTDVSYLACAKKLLGAPDAVYPQ
FATHNAHTLAAIYHLAGQNYYPGQYEFQCLHGMGEPLYEEVTGRDKLNRPCRVYAPVGTHETLLAYLVRRLLENGANTSF
VNRIADKTVPVKELVADPVDEASKVVPLGAPHAKIPLPRNLYGDERPNSMGLDLSNEHRLASLSSALLASAHHPWRAAPM
LADDALADAPARDVRNPADQRDVVGTVSEATSEHVSAALAHAVAAAPIWQATPVDARADCLVRAADLLEAQMHTLMGLIV
REAGKSLPNAIAEIREAVDFLRYYAAQIRGEFSNDTHRPLGPVVCISPWNFPLAIFMGQVAAALAAGNTVLAKPAEQTPL
IAAQAVRLLREAGVPAGAVQLLPGTGETVGAALVADPRTRAVMFTGSTEVARLINKTLAARLDPDGKPIPLIAETGGQNA
MIVDSSALAEQVVADVMQSSFDSAGQRCSALRVLCLQDDVADRTLTMLKGAMHELALGNPDRLSTDVGPVIDAEAKQTID
THVAAMKDKGHAVTQLPMPDACAHGTFVPPTLIEIGSIDELKREVFGPVLHVVRYRRSQLDKLLEQIRATGYGLTLGIHT
RIDETIAHVISNAHVGNIYVNRNVIGAVVGVQPFGGEGLSGTGPKAGGALYLQRLLATRPSGLPRALAQSLVADGATESD
ARGNPAAALTTLRDWLIEQREPALAARCDGYLAQVPAGATAVLSGPTGERNTYTLGPRGTVLCVAATPGGARAQFAAVLA
TGNRALFAGAAGEALVAALPASLKAHAAVRKQADAPFDAVLFEGDSDELQTLVKDVAQRPGPIVSVQGVSAGAFENGDAE
DYALERLLTERSVSVNTAAAGGNANLMTIG
>Mature_1309_residues
ASTTLGVKVDDLLRSRLKDAAARLERTPHWLIKQAIFAYLERIEHGQLPPELSGHSGVTELADGQATDGDDDNSPHPFLE
FAQNVQPQSVLRAAITAAYRRPEPECVPFLLGQARLPANLQADVQALATKLVEALREKSSGGGVEGLIHEFSLSSQEGVA
LMCLAEALLRIPDRATRDALIRDKISKGDWRSHVGHAPSLFVNAATWGLMITGKLVTTNSEAGLSSALTRLIGRGGEPLI
RKGVDMAMRLMGEQFVTGETISEALANSRKYEARGFRYSYDMLGEAATTEEDAQRYYASYEQAIHAIGKAAGGRGIYEGP
GISIKLSALHARYSRSQQDRTMSELLPRVRALALLARRYDIGLNIDAEEADRLELSLDLLEALCFDPELAGWNGIGFVVQ
GYQKRCPFVIDYLIDLARRSRHRLMIRLVKGAYWDSEIKRAQVDGLEGYPVYTRKIYTDVSYLACAKKLLGAPDAVYPQF
ATHNAHTLAAIYHLAGQNYYPGQYEFQCLHGMGEPLYEEVTGRDKLNRPCRVYAPVGTHETLLAYLVRRLLENGANTSFV
NRIADKTVPVKELVADPVDEASKVVPLGAPHAKIPLPRNLYGDERPNSMGLDLSNEHRLASLSSALLASAHHPWRAAPML
ADDALADAPARDVRNPADQRDVVGTVSEATSEHVSAALAHAVAAAPIWQATPVDARADCLVRAADLLEAQMHTLMGLIVR
EAGKSLPNAIAEIREAVDFLRYYAAQIRGEFSNDTHRPLGPVVCISPWNFPLAIFMGQVAAALAAGNTVLAKPAEQTPLI
AAQAVRLLREAGVPAGAVQLLPGTGETVGAALVADPRTRAVMFTGSTEVARLINKTLAARLDPDGKPIPLIAETGGQNAM
IVDSSALAEQVVADVMQSSFDSAGQRCSALRVLCLQDDVADRTLTMLKGAMHELALGNPDRLSTDVGPVIDAEAKQTIDT
HVAAMKDKGHAVTQLPMPDACAHGTFVPPTLIEIGSIDELKREVFGPVLHVVRYRRSQLDKLLEQIRATGYGLTLGIHTR
IDETIAHVISNAHVGNIYVNRNVIGAVVGVQPFGGEGLSGTGPKAGGALYLQRLLATRPSGLPRALAQSLVADGATESDA
RGNPAAALTTLRDWLIEQREPALAARCDGYLAQVPAGATAVLSGPTGERNTYTLGPRGTVLCVAATPGGARAQFAAVLAT
GNRALFAGAAGEALVAALPASLKAHAAVRKQADAPFDAVLFEGDSDELQTLVKDVAQRPGPIVSVQGVSAGAFENGDAED
YALERLLTERSVSVNTAAAGGNANLMTIG

Specific function: Oxidizes proline to glutamate for use as a carbon and nitrogen source and also function as a transcriptional repressor of the put operon [H]

COG id: COG4230

COG function: function code C; Delta 1-pyrroline-5-carboxylate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the aldehyde dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI21361176, Length=453, Percent_Identity=32.4503311258278, Blast_Score=186, Evalue=9e-47,
Organism=Homo sapiens, GI153266822, Length=451, Percent_Identity=30.5986696230599, Blast_Score=177, Evalue=6e-44,
Organism=Homo sapiens, GI25777732, Length=447, Percent_Identity=31.3199105145414, Blast_Score=170, Evalue=1e-41,
Organism=Homo sapiens, GI25777730, Length=450, Percent_Identity=30.6666666666667, Blast_Score=169, Evalue=2e-41,
Organism=Homo sapiens, GI25777736, Length=465, Percent_Identity=30.3225806451613, Blast_Score=169, Evalue=2e-41,
Organism=Homo sapiens, GI25777734, Length=465, Percent_Identity=30.3225806451613, Blast_Score=169, Evalue=2e-41,
Organism=Homo sapiens, GI238859541, Length=465, Percent_Identity=30.3225806451613, Blast_Score=168, Evalue=3e-41,
Organism=Homo sapiens, GI25777724, Length=452, Percent_Identity=29.646017699115, Blast_Score=167, Evalue=5e-41,
Organism=Homo sapiens, GI21614513, Length=431, Percent_Identity=30.8584686774942, Blast_Score=162, Evalue=2e-39,
Organism=Homo sapiens, GI25777728, Length=406, Percent_Identity=30.2955665024631, Blast_Score=160, Evalue=1e-38,
Organism=Homo sapiens, GI12007648, Length=444, Percent_Identity=28.8288288288288, Blast_Score=154, Evalue=7e-37,
Organism=Homo sapiens, GI238814322, Length=423, Percent_Identity=28.1323877068558, Blast_Score=152, Evalue=3e-36,
Organism=Homo sapiens, GI4507229, Length=496, Percent_Identity=29.2338709677419, Blast_Score=149, Evalue=2e-35,
Organism=Homo sapiens, GI115387104, Length=449, Percent_Identity=27.1714922048998, Blast_Score=140, Evalue=7e-33,
Organism=Homo sapiens, GI25777721, Length=509, Percent_Identity=28.2907662082515, Blast_Score=138, Evalue=3e-32,
Organism=Homo sapiens, GI11095441, Length=425, Percent_Identity=27.7647058823529, Blast_Score=135, Evalue=3e-31,
Organism=Homo sapiens, GI310128103, Length=463, Percent_Identity=26.133909287257, Blast_Score=132, Evalue=3e-30,
Organism=Homo sapiens, GI310128093, Length=461, Percent_Identity=26.6811279826464, Blast_Score=132, Evalue=3e-30,
Organism=Homo sapiens, GI188035924, Length=463, Percent_Identity=26.133909287257, Blast_Score=131, Evalue=4e-30,
Organism=Homo sapiens, GI25952152, Length=438, Percent_Identity=27.8538812785388, Blast_Score=128, Evalue=4e-29,
Organism=Homo sapiens, GI25777726, Length=452, Percent_Identity=25.4424778761062, Blast_Score=116, Evalue=1e-25,
Organism=Homo sapiens, GI310128091, Length=396, Percent_Identity=27.020202020202, Blast_Score=115, Evalue=2e-25,
Organism=Homo sapiens, GI206597441, Length=463, Percent_Identity=25.2699784017279, Blast_Score=99, Evalue=3e-20,
Organism=Homo sapiens, GI206597439, Length=463, Percent_Identity=25.2699784017279, Blast_Score=99, Evalue=3e-20,
Organism=Homo sapiens, GI22907049, Length=463, Percent_Identity=25.2699784017279, Blast_Score=99, Evalue=3e-20,
Organism=Homo sapiens, GI310128087, Length=304, Percent_Identity=25.9868421052632, Blast_Score=97, Evalue=1e-19,
Organism=Homo sapiens, GI71773324, Length=385, Percent_Identity=25.1948051948052, Blast_Score=96, Evalue=3e-19,
Organism=Homo sapiens, GI4502043, Length=329, Percent_Identity=24.9240121580547, Blast_Score=94, Evalue=1e-18,
Organism=Homo sapiens, GI238814371, Length=329, Percent_Identity=24.9240121580547, Blast_Score=94, Evalue=1e-18,
Organism=Homo sapiens, GI310128089, Length=336, Percent_Identity=25.8928571428571, Blast_Score=87, Evalue=1e-16,
Organism=Homo sapiens, GI310128095, Length=322, Percent_Identity=26.0869565217391, Blast_Score=82, Evalue=5e-15,
Organism=Homo sapiens, GI301500698, Length=432, Percent_Identity=24.3055555555556, Blast_Score=80, Evalue=1e-14,
Organism=Homo sapiens, GI310128101, Length=223, Percent_Identity=26.9058295964126, Blast_Score=79, Evalue=3e-14,
Organism=Homo sapiens, GI73695881, Length=354, Percent_Identity=23.1638418079096, Blast_Score=78, Evalue=5e-14,
Organism=Homo sapiens, GI73695879, Length=354, Percent_Identity=23.1638418079096, Blast_Score=78, Evalue=5e-14,
Organism=Homo sapiens, GI310128099, Length=222, Percent_Identity=27.027027027027, Blast_Score=78, Evalue=7e-14,
Organism=Homo sapiens, GI4557303, Length=331, Percent_Identity=22.6586102719033, Blast_Score=77, Evalue=8e-14,
Organism=Homo sapiens, GI73466520, Length=331, Percent_Identity=22.6586102719033, Blast_Score=77, Evalue=1e-13,
Organism=Homo sapiens, GI310128097, Length=269, Percent_Identity=26.0223048327138, Blast_Score=74, Evalue=7e-13,
Organism=Homo sapiens, GI223972651, Length=313, Percent_Identity=27.7955271565495, Blast_Score=68, Evalue=5e-11,
Organism=Escherichia coli, GI1787250, Length=1338, Percent_Identity=66.2929745889387, Blast_Score=1720, Evalue=0.0,
Organism=Escherichia coli, GI1789015, Length=462, Percent_Identity=30.5194805194805, Blast_Score=181, Evalue=2e-46,
Organism=Escherichia coli, GI1787715, Length=446, Percent_Identity=32.7354260089686, Blast_Score=169, Evalue=1e-42,
Organism=Escherichia coli, GI1787684, Length=460, Percent_Identity=29.7826086956522, Blast_Score=165, Evalue=1e-41,
Organism=Escherichia coli, GI1788042, Length=448, Percent_Identity=31.0267857142857, Blast_Score=157, Evalue=5e-39,
Organism=Escherichia coli, GI1786504, Length=483, Percent_Identity=28.7784679089027, Blast_Score=147, Evalue=6e-36,
Organism=Escherichia coli, GI1787558, Length=411, Percent_Identity=30.4136253041363, Blast_Score=145, Evalue=1e-35,
Organism=Escherichia coli, GI87081896, Length=413, Percent_Identity=29.5399515738499, Blast_Score=144, Evalue=5e-35,
Organism=Escherichia coli, GI87082295, Length=448, Percent_Identity=27.9017857142857, Blast_Score=130, Evalue=7e-31,
Organism=Escherichia coli, GI87081926, Length=428, Percent_Identity=26.1682242990654, Blast_Score=111, Evalue=3e-25,
Organism=Escherichia coli, GI1787653, Length=378, Percent_Identity=23.8095238095238, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17534447, Length=462, Percent_Identity=31.8181818181818, Blast_Score=184, Evalue=2e-46,
Organism=Caenorhabditis elegans, GI25144435, Length=456, Percent_Identity=32.6754385964912, Blast_Score=177, Evalue=4e-44,
Organism=Caenorhabditis elegans, GI32564736, Length=411, Percent_Identity=33.3333333333333, Blast_Score=169, Evalue=6e-42,
Organism=Caenorhabditis elegans, GI17562198, Length=493, Percent_Identity=29.6146044624746, Blast_Score=165, Evalue=1e-40,
Organism=Caenorhabditis elegans, GI115532534, Length=375, Percent_Identity=32.2666666666667, Blast_Score=155, Evalue=1e-37,
Organism=Caenorhabditis elegans, GI115534176, Length=454, Percent_Identity=29.295154185022, Blast_Score=155, Evalue=2e-37,
Organism=Caenorhabditis elegans, GI133930964, Length=440, Percent_Identity=28.4090909090909, Blast_Score=147, Evalue=5e-35,
Organism=Caenorhabditis elegans, GI25143874, Length=511, Percent_Identity=26.2230919765166, Blast_Score=146, Evalue=9e-35,
Organism=Caenorhabditis elegans, GI32564151, Length=415, Percent_Identity=29.8795180722892, Blast_Score=145, Evalue=1e-34,
Organism=Caenorhabditis elegans, GI25143876, Length=512, Percent_Identity=26.3671875, Blast_Score=144, Evalue=3e-34,
Organism=Caenorhabditis elegans, GI71986308, Length=427, Percent_Identity=28.5714285714286, Blast_Score=137, Evalue=3e-32,
Organism=Caenorhabditis elegans, GI17551164, Length=453, Percent_Identity=26.2693156732892, Blast_Score=132, Evalue=1e-30,
Organism=Caenorhabditis elegans, GI17534119, Length=455, Percent_Identity=27.6923076923077, Blast_Score=127, Evalue=4e-29,
Organism=Caenorhabditis elegans, GI71995606, Length=443, Percent_Identity=26.86230248307, Blast_Score=120, Evalue=3e-27,
Organism=Caenorhabditis elegans, GI71995613, Length=400, Percent_Identity=26.75, Blast_Score=118, Evalue=2e-26,
Organism=Caenorhabditis elegans, GI71990744, Length=302, Percent_Identity=30.1324503311258, Blast_Score=114, Evalue=2e-25,
Organism=Caenorhabditis elegans, GI25146391, Length=326, Percent_Identity=25.1533742331288, Blast_Score=95, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI25146394, Length=326, Percent_Identity=25.1533742331288, Blast_Score=95, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI32566756, Length=326, Percent_Identity=25.1533742331288, Blast_Score=95, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17564084, Length=330, Percent_Identity=25.1515151515152, Blast_Score=89, Evalue=2e-17,
Organism=Saccharomyces cerevisiae, GI6320917, Length=460, Percent_Identity=32.6086956521739, Blast_Score=192, Evalue=4e-49,
Organism=Saccharomyces cerevisiae, GI6325196, Length=463, Percent_Identity=30.6695464362851, Blast_Score=177, Evalue=1e-44,
Organism=Saccharomyces cerevisiae, GI6321826, Length=482, Percent_Identity=30.4979253112033, Blast_Score=171, Evalue=6e-43,
Organism=Saccharomyces cerevisiae, GI6324950, Length=450, Percent_Identity=28.6666666666667, Blast_Score=166, Evalue=2e-41,
Organism=Saccharomyces cerevisiae, GI6323821, Length=470, Percent_Identity=30.2127659574468, Blast_Score=162, Evalue=3e-40,
Organism=Saccharomyces cerevisiae, GI6323822, Length=474, Percent_Identity=29.1139240506329, Blast_Score=158, Evalue=7e-39,
Organism=Saccharomyces cerevisiae, GI6319478, Length=462, Percent_Identity=27.9220779220779, Blast_Score=134, Evalue=1e-31,
Organism=Saccharomyces cerevisiae, GI6321828, Length=475, Percent_Identity=23.7894736842105, Blast_Score=98, Evalue=1e-20,
Organism=Saccharomyces cerevisiae, GI6323757, Length=326, Percent_Identity=25.7668711656442, Blast_Score=77, Evalue=3e-14,
Organism=Drosophila melanogaster, GI20129399, Length=444, Percent_Identity=29.954954954955, Blast_Score=168, Evalue=3e-41,
Organism=Drosophila melanogaster, GI281362580, Length=473, Percent_Identity=29.3868921775898, Blast_Score=167, Evalue=7e-41,
Organism=Drosophila melanogaster, GI62472918, Length=473, Percent_Identity=29.3868921775898, Blast_Score=167, Evalue=7e-41,
Organism=Drosophila melanogaster, GI62472926, Length=473, Percent_Identity=29.3868921775898, Blast_Score=167, Evalue=7e-41,
Organism=Drosophila melanogaster, GI62472936, Length=473, Percent_Identity=29.3868921775898, Blast_Score=167, Evalue=7e-41,
Organism=Drosophila melanogaster, GI21356737, Length=473, Percent_Identity=29.3868921775898, Blast_Score=167, Evalue=7e-41,
Organism=Drosophila melanogaster, GI24650465, Length=448, Percent_Identity=28.3482142857143, Blast_Score=157, Evalue=5e-38,
Organism=Drosophila melanogaster, GI24668425, Length=481, Percent_Identity=25.987525987526, Blast_Score=157, Evalue=7e-38,
Organism=Drosophila melanogaster, GI24668417, Length=481, Percent_Identity=25.987525987526, Blast_Score=157, Evalue=7e-38,
Organism=Drosophila melanogaster, GI24668413, Length=481, Percent_Identity=25.987525987526, Blast_Score=157, Evalue=7e-38,
Organism=Drosophila melanogaster, GI24585660, Length=474, Percent_Identity=26.7932489451477, Blast_Score=147, Evalue=6e-35,
Organism=Drosophila melanogaster, GI28574525, Length=493, Percent_Identity=26.369168356998, Blast_Score=143, Evalue=7e-34,
Organism=Drosophila melanogaster, GI24666674, Length=481, Percent_Identity=27.8586278586279, Blast_Score=141, Evalue=3e-33,
Organism=Drosophila melanogaster, GI28571806, Length=459, Percent_Identity=25.4901960784314, Blast_Score=137, Evalue=6e-32,
Organism=Drosophila melanogaster, GI28571802, Length=459, Percent_Identity=25.4901960784314, Blast_Score=137, Evalue=7e-32,
Organism=Drosophila melanogaster, GI28571800, Length=459, Percent_Identity=25.4901960784314, Blast_Score=137, Evalue=7e-32,
Organism=Drosophila melanogaster, GI28571798, Length=459, Percent_Identity=25.4901960784314, Blast_Score=137, Evalue=8e-32,
Organism=Drosophila melanogaster, GI28571796, Length=459, Percent_Identity=25.4901960784314, Blast_Score=137, Evalue=8e-32,
Organism=Drosophila melanogaster, GI28571794, Length=459, Percent_Identity=25.4901960784314, Blast_Score=137, Evalue=8e-32,
Organism=Drosophila melanogaster, GI24638878, Length=428, Percent_Identity=26.8691588785047, Blast_Score=115, Evalue=2e-25,
Organism=Drosophila melanogaster, GI24638876, Length=428, Percent_Identity=26.8691588785047, Blast_Score=115, Evalue=2e-25,
Organism=Drosophila melanogaster, GI281360299, Length=391, Percent_Identity=27.6214833759591, Blast_Score=101, Evalue=4e-21,
Organism=Drosophila melanogaster, GI281360297, Length=391, Percent_Identity=27.6214833759591, Blast_Score=101, Evalue=4e-21,
Organism=Drosophila melanogaster, GI281360295, Length=391, Percent_Identity=27.6214833759591, Blast_Score=101, Evalue=4e-21,
Organism=Drosophila melanogaster, GI24586250, Length=391, Percent_Identity=27.6214833759591, Blast_Score=101, Evalue=4e-21,
Organism=Drosophila melanogaster, GI281360301, Length=391, Percent_Identity=27.1099744245524, Blast_Score=101, Evalue=5e-21,
Organism=Drosophila melanogaster, GI45552499, Length=391, Percent_Identity=26.0869565217391, Blast_Score=95, Evalue=3e-19,
Organism=Drosophila melanogaster, GI281360303, Length=391, Percent_Identity=26.0869565217391, Blast_Score=95, Evalue=3e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016161
- InterPro:   IPR016163
- InterPro:   IPR016160
- InterPro:   IPR016162
- InterPro:   IPR015590
- InterPro:   IPR005933
- InterPro:   IPR002872 [H]

Pfam domain/function: PF00171 Aldedh; PF01619 Pro_dh [H]

EC number: =1.5.99.8; =1.5.1.12 [H]

Molecular weight: Translated: 140126; Mature: 139995

Theoretical pI: Translated: 6.31; Mature: 6.31

Prosite motif: PS00070 ALDEHYDE_DEHYDR_CYS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MASTTLGVKVDDLLRSRLKDAAARLERTPHWLIKQAIFAYLERIEHGQLPPELSGHSGVT
CCCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCH
ELADGQATDGDDDNSPHPFLEFAQNVQPQSVLRAAITAAYRRPEPECVPFLLGQARLPAN
HHCCCCCCCCCCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHCCCCCHHHHHHCCCCCCCC
LQADVQALATKLVEALREKSSGGGVEGLIHEFSLSSQEGVALMCLAEALLRIPDRATRDA
CHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCHHHHHH
LIRDKISKGDWRSHVGHAPSLFVNAATWGLMITGKLVTTNSEAGLSSALTRLIGRGGEPL
HHHHHCCCCCHHHHCCCCCHHEEEHHHEEEEEEEEEEECCCCCCHHHHHHHHHCCCCCHH
IRKGVDMAMRLMGEQFVTGETISEALANSRKYEARGFRYSYDMLGEAATTEEDAQRYYAS
HHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCCEEEHHHHCCCCCCHHHHHHHHHH
YEQAIHAIGKAAGGRGIYEGPGISIKLSALHARYSRSQQDRTMSELLPRVRALALLARRY
HHHHHHHHHHHCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DIGLNIDAEEADRLELSLDLLEALCFDPELAGWNGIGFVVQGYQKRCPFVIDYLIDLARR
CCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCHHHEECHHHCCCHHHHHHHHHHHH
SRHRLMIRLVKGAYWDSEIKRAQVDGLEGYPVYTRKIYTDVSYLACAKKLLGAPDAVYPQ
HHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCC
FATHNAHTLAAIYHLAGQNYYPGQYEFQCLHGMGEPLYEEVTGRDKLNRPCRVYAPVGTH
HHCCCHHHHHHHHHHHCCCCCCCCCCHHHHHCCCCHHHHHHCCHHHCCCCEEEEECCCCH
ETLLAYLVRRLLENGANTSFVNRIADKTVPVKELVADPVDEASKVVPLGAPHAKIPLPRN
HHHHHHHHHHHHHCCCCHHHHHHHHHCCCCHHHHHCCCHHHHHCEEECCCCCCCCCCCCC
LYGDERPNSMGLDLSNEHRLASLSSALLASAHHPWRAAPMLADDALADAPARDVRNPADQ
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCHHHHHHCCCCHHHHCCCCCH
RDVVGTVSEATSEHVSAALAHAVAAAPIWQATPVDARADCLVRAADLLEAQMHTLMGLIV
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
REAGKSLPNAIAEIREAVDFLRYYAAQIRGEFSNDTHRPLGPVVCISPWNFPLAIFMGQV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEECCCCCHHHHHHHHH
AAALAAGNTVLAKPAEQTPLIAAQAVRLLREAGVPAGAVQLLPGTGETVGAALVADPRTR
HHHHHCCCEEEECCCCCCCHHHHHHHHHHHHCCCCCCEEEEECCCCCHHCEEEEECCCCC
AVMFTGSTEVARLINKTLAARLDPDGKPIPLIAETGGQNAMIVDSSALAEQVVADVMQSS
EEEEECCHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCEEEEEHHHHHHHHHHHHHHHH
FDSAGQRCSALRVLCLQDDVADRTLTMLKGAMHELALGNPDRLSTDVGPVIDAEAKQTID
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHH
THVAAMKDKGHAVTQLPMPDACAHGTFVPPTLIEIGSIDELKREVFGPVLHVVRYRRSQL
HHHHHHHCCCCEEEECCCCCHHCCCCCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
DKLLEQIRATGYGLTLGIHTRIDETIAHVISNAHVGNIYVNRNVIGAVVGVQPFGGEGLS
HHHHHHHHHCCCEEEEEEHHHHHHHHHHHHHCCCCCEEEECCCEEEEEEECCCCCCCCCC
GTGPKAGGALYLQRLLATRPSGLPRALAQSLVADGATESDARGNPAAALTTLRDWLIEQR
CCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHCC
EPALAARCDGYLAQVPAGATAVLSGPTGERNTYTLGPRGTVLCVAATPGGARAQFAAVLA
CCHHHHHHCCHHHHCCCCCEEEEECCCCCCCCEEECCCCEEEEEEECCCCCHHHEEEEEE
TGNRALFAGAAGEALVAALPASLKAHAAVRKQADAPFDAVLFEGDSDELQTLVKDVAQRP
ECCCEEEECCCCHHHHHHHCHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHHCC
GPIVSVQGVSAGAFENGDAEDYALERLLTERSVSVNTAAAGGNANLMTIG
CCEEEECCCCCCCCCCCCHHHHHHHHHHHHCCCCCEEECCCCCCCEEEEC
>Mature Secondary Structure 
ASTTLGVKVDDLLRSRLKDAAARLERTPHWLIKQAIFAYLERIEHGQLPPELSGHSGVT
CCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCH
ELADGQATDGDDDNSPHPFLEFAQNVQPQSVLRAAITAAYRRPEPECVPFLLGQARLPAN
HHCCCCCCCCCCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHCCCCCHHHHHHCCCCCCCC
LQADVQALATKLVEALREKSSGGGVEGLIHEFSLSSQEGVALMCLAEALLRIPDRATRDA
CHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCHHHHHH
LIRDKISKGDWRSHVGHAPSLFVNAATWGLMITGKLVTTNSEAGLSSALTRLIGRGGEPL
HHHHHCCCCCHHHHCCCCCHHEEEHHHEEEEEEEEEEECCCCCCHHHHHHHHHCCCCCHH
IRKGVDMAMRLMGEQFVTGETISEALANSRKYEARGFRYSYDMLGEAATTEEDAQRYYAS
HHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCCEEEHHHHCCCCCCHHHHHHHHHH
YEQAIHAIGKAAGGRGIYEGPGISIKLSALHARYSRSQQDRTMSELLPRVRALALLARRY
HHHHHHHHHHHCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DIGLNIDAEEADRLELSLDLLEALCFDPELAGWNGIGFVVQGYQKRCPFVIDYLIDLARR
CCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCHHHEECHHHCCCHHHHHHHHHHHH
SRHRLMIRLVKGAYWDSEIKRAQVDGLEGYPVYTRKIYTDVSYLACAKKLLGAPDAVYPQ
HHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCC
FATHNAHTLAAIYHLAGQNYYPGQYEFQCLHGMGEPLYEEVTGRDKLNRPCRVYAPVGTH
HHCCCHHHHHHHHHHHCCCCCCCCCCHHHHHCCCCHHHHHHCCHHHCCCCEEEEECCCCH
ETLLAYLVRRLLENGANTSFVNRIADKTVPVKELVADPVDEASKVVPLGAPHAKIPLPRN
HHHHHHHHHHHHHCCCCHHHHHHHHHCCCCHHHHHCCCHHHHHCEEECCCCCCCCCCCCC
LYGDERPNSMGLDLSNEHRLASLSSALLASAHHPWRAAPMLADDALADAPARDVRNPADQ
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCHHHHHHCCCCHHHHCCCCCH
RDVVGTVSEATSEHVSAALAHAVAAAPIWQATPVDARADCLVRAADLLEAQMHTLMGLIV
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
REAGKSLPNAIAEIREAVDFLRYYAAQIRGEFSNDTHRPLGPVVCISPWNFPLAIFMGQV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEECCCCCHHHHHHHHH
AAALAAGNTVLAKPAEQTPLIAAQAVRLLREAGVPAGAVQLLPGTGETVGAALVADPRTR
HHHHHCCCEEEECCCCCCCHHHHHHHHHHHHCCCCCCEEEEECCCCCHHCEEEEECCCCC
AVMFTGSTEVARLINKTLAARLDPDGKPIPLIAETGGQNAMIVDSSALAEQVVADVMQSS
EEEEECCHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCEEEEEHHHHHHHHHHHHHHHH
FDSAGQRCSALRVLCLQDDVADRTLTMLKGAMHELALGNPDRLSTDVGPVIDAEAKQTID
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHH
THVAAMKDKGHAVTQLPMPDACAHGTFVPPTLIEIGSIDELKREVFGPVLHVVRYRRSQL
HHHHHHHCCCCEEEECCCCCHHCCCCCCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
DKLLEQIRATGYGLTLGIHTRIDETIAHVISNAHVGNIYVNRNVIGAVVGVQPFGGEGLS
HHHHHHHHHCCCEEEEEEHHHHHHHHHHHHHCCCCCEEEECCCEEEEEEECCCCCCCCCC
GTGPKAGGALYLQRLLATRPSGLPRALAQSLVADGATESDARGNPAAALTTLRDWLIEQR
CCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHCC
EPALAARCDGYLAQVPAGATAVLSGPTGERNTYTLGPRGTVLCVAATPGGARAQFAAVLA
CCHHHHHHCCHHHHCCCCCEEEEECCCCCCCCEEECCCCEEEEEEECCCCCHHHEEEEEE
TGNRALFAGAAGEALVAALPASLKAHAAVRKQADAPFDAVLFEGDSDELQTLVKDVAQRP
ECCCEEEECCCCHHHHHHHCHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHHCC
GPIVSVQGVSAGAFENGDAEDYALERLLTERSVSVNTAAAGGNANLMTIG
CCEEEECCCCCCCCCCCCHHHHHHHHHHHHCCCCCEEECCCCCCCEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7966312; 8905232; 9278503; 3325781; 12514740 [H]