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The map label for this gene is sufS [C]

Identifier: 116626730

GI number: 116626730

Start: 9676239

End: 9677489

Strand: Direct

Name: sufS [C]

Synonym: Acid_7702

Alternate gene names: 116626730

Gene position: 9676239-9677489 (Clockwise)

Preceding gene: 116626729

Following gene: 116626731

Centisome position: 97.1

GC content: 60.19

Gene sequence:

>1251_bases
ATGAGCACGCTGAGTAGCACCCCTACCGCCGCAAGTTTCGACGTGGAGAAGATCCGCGAGGATTTCCCCGTCCTCAAGCA
GAAGGTCCACGGCAAGCCGCTTGTCTATCTCGATAGCGCCGCCACCGCCCAAAAACCCTTGGCAGTGATTGACGCCATCC
GCCGCTTCCACGAAGTCGATTGCGCCAACATCCACCGCGGCGTCCACGAACTCTCCCAGCGCTCCACCGCTGCATATGAA
GAGACCCGCGCCAAGGCCAAACGCTTCCTTAACGCTCGCAGCAAGGACGAATTGATCTTCGTCCGCGGCACCACCGAGGG
CATCAATCTCGTCACCAGCTCCTGGGGCCGCCGCAACGTCAAGGAAGGCGACGAGATCATCGTCTCCGCCATGGAGCACC
ATTCCAACATCGTGCCGTGGCAGATGCTCTGCCTCGACACGGGCGCGAATCTCCGCGTCATCCCCATGAACGAGCGCGGC
GAACTCATTATGGAGGAGTACGAAAAGCTCCTCAATCCGCGTACCAAAATGGTCGCTGTCGCCCATGTCTCCAATGCGCT
CGGCACCATCAACCCCGTCCGCCAGATCATCGAAATGGCGCACAATGTCGGCGCGCTGACCCTGATCGATGGCGCCCAGG
CGGTCCCCCACGCGAAGGTCGATCTCCAGGCCCTTGACGCCGATTTCTATACCTTCAGCGGCCACAAGATCGTCGGGCCC
ACCGGCATCGGCATTCTCTACGGAAAGACCAAACTCCTCAACGCCATGCCCCCCTACCAGGGCGGCGGCGACATGATCAA
AGTAGTCACTTTCGAAAAAACCACCTACGCCGACCTGCCCTATAAGTTCGAAGCCGGCACGCCCAATATCGCCGGCGGCA
TCGGCCTTGGCGCCGCGTTGGATTACGTGACCGCACTCGGCATTGAACAGATCGCCGCCTACGAACACCAACTGCTCGAG
TACGGCACCGAACAGCTCTCCGGCATTCCAGGCCTGAGGCTGATCGGCACCGCGAAGGAGAAGGCCAGCGTGCTCTCCTT
CGTCATCGAAGGCATTCACCCTCACGACATCGGCACCATTCTCGATAAACAGGGAATCGCCGTCCGCACAGGCCATCACT
GCGCGCAGCCCGTGATGGATTTCTTCAACGTCCCGGCGACCACCCGCGCCTCGCTCGCGTTCTACAACACCTTTGGCGAA
ATCGATGCGCTCGTCGGCGGACTCAAAAAGGTAAAGGAGATTTTCTCCTAA

Upstream 100 bases:

>100_bases
CGAAACCTTCTGGTCTTCGCCTTCGCGCAGGACGTGGTCGATCGCATCAAAGTGCAGTCACTACGGGATTCGCTGGAAAA
AATCCTGTTCGAGAAATTCC

Downstream 100 bases:

>100_bases
TGGTTCACGATCTCTACCAGGAAATTATCCTGGATCACAGCAAGCGTCCCCGCAATTGTCACACCATGGAGAACGCCACC
GGTCACGCCGATGGCTACAA

Product: cysteine desulfurase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 416; Mature: 415

Protein sequence:

>416_residues
MSTLSSTPTAASFDVEKIREDFPVLKQKVHGKPLVYLDSAATAQKPLAVIDAIRRFHEVDCANIHRGVHELSQRSTAAYE
ETRAKAKRFLNARSKDELIFVRGTTEGINLVTSSWGRRNVKEGDEIIVSAMEHHSNIVPWQMLCLDTGANLRVIPMNERG
ELIMEEYEKLLNPRTKMVAVAHVSNALGTINPVRQIIEMAHNVGALTLIDGAQAVPHAKVDLQALDADFYTFSGHKIVGP
TGIGILYGKTKLLNAMPPYQGGGDMIKVVTFEKTTYADLPYKFEAGTPNIAGGIGLGAALDYVTALGIEQIAAYEHQLLE
YGTEQLSGIPGLRLIGTAKEKASVLSFVIEGIHPHDIGTILDKQGIAVRTGHHCAQPVMDFFNVPATTRASLAFYNTFGE
IDALVGGLKKVKEIFS

Sequences:

>Translated_416_residues
MSTLSSTPTAASFDVEKIREDFPVLKQKVHGKPLVYLDSAATAQKPLAVIDAIRRFHEVDCANIHRGVHELSQRSTAAYE
ETRAKAKRFLNARSKDELIFVRGTTEGINLVTSSWGRRNVKEGDEIIVSAMEHHSNIVPWQMLCLDTGANLRVIPMNERG
ELIMEEYEKLLNPRTKMVAVAHVSNALGTINPVRQIIEMAHNVGALTLIDGAQAVPHAKVDLQALDADFYTFSGHKIVGP
TGIGILYGKTKLLNAMPPYQGGGDMIKVVTFEKTTYADLPYKFEAGTPNIAGGIGLGAALDYVTALGIEQIAAYEHQLLE
YGTEQLSGIPGLRLIGTAKEKASVLSFVIEGIHPHDIGTILDKQGIAVRTGHHCAQPVMDFFNVPATTRASLAFYNTFGE
IDALVGGLKKVKEIFS
>Mature_415_residues
STLSSTPTAASFDVEKIREDFPVLKQKVHGKPLVYLDSAATAQKPLAVIDAIRRFHEVDCANIHRGVHELSQRSTAAYEE
TRAKAKRFLNARSKDELIFVRGTTEGINLVTSSWGRRNVKEGDEIIVSAMEHHSNIVPWQMLCLDTGANLRVIPMNERGE
LIMEEYEKLLNPRTKMVAVAHVSNALGTINPVRQIIEMAHNVGALTLIDGAQAVPHAKVDLQALDADFYTFSGHKIVGPT
GIGILYGKTKLLNAMPPYQGGGDMIKVVTFEKTTYADLPYKFEAGTPNIAGGIGLGAALDYVTALGIEQIAAYEHQLLEY
GTEQLSGIPGLRLIGTAKEKASVLSFVIEGIHPHDIGTILDKQGIAVRTGHHCAQPVMDFFNVPATTRASLAFYNTFGEI
DALVGGLKKVKEIFS

Specific function: Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine [H]

COG id: COG0520

COG function: function code E; Selenocysteine lyase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily [H]

Homologues:

Organism=Homo sapiens, GI32307132, Length=295, Percent_Identity=25.7627118644068, Blast_Score=90, Evalue=3e-18,
Organism=Escherichia coli, GI1787970, Length=404, Percent_Identity=55.9405940594059, Blast_Score=473, Evalue=1e-135,
Organism=Escherichia coli, GI1789175, Length=403, Percent_Identity=41.6873449131514, Blast_Score=336, Evalue=2e-93,
Organism=Escherichia coli, GI48994898, Length=219, Percent_Identity=28.7671232876712, Blast_Score=88, Evalue=8e-19,
Organism=Caenorhabditis elegans, GI25143064, Length=217, Percent_Identity=26.7281105990783, Blast_Score=98, Evalue=8e-21,
Organism=Caenorhabditis elegans, GI193211090, Length=373, Percent_Identity=25.201072386059, Blast_Score=88, Evalue=8e-18,
Organism=Saccharomyces cerevisiae, GI6319831, Length=229, Percent_Identity=28.3842794759825, Blast_Score=101, Evalue=2e-22,
Organism=Drosophila melanogaster, GI20129463, Length=262, Percent_Identity=27.0992366412214, Blast_Score=104, Evalue=1e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000192
- InterPro:   IPR010970
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00266 Aminotran_5 [H]

EC number: =2.8.1.7 [H]

Molecular weight: Translated: 45327; Mature: 45195

Theoretical pI: Translated: 6.93; Mature: 6.93

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTLSSTPTAASFDVEKIREDFPVLKQKVHGKPLVYLDSAATAQKPLAVIDAIRRFHEVD
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCHHHHHHHHHHHHHCC
CANIHRGVHELSQRSTAAYEETRAKAKRFLNARSKDELIFVRGTTEGINLVTSSWGRRNV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCHHHHCCCCCCCC
KEGDEIIVSAMEHHSNIVPWQMLCLDTGANLRVIPMNERGELIMEEYEKLLNPRTKMVAV
CCHHHHHHHHHHHCCCCCCCEEEEEECCCCEEEEECCCCCCHHHHHHHHHHCCHHHEEEH
AHVSNALGTINPVRQIIEMAHNVGALTLIDGAQAVPHAKVDLQALDADFYTFSGHKIVGP
HHHHHHHCCHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCCEEECCCEEEECCCEEECC
TGIGILYGKTKLLNAMPPYQGGGDMIKVVTFEKTTYADLPYKFEAGTPNIAGGIGLGAAL
CCCEEEECCHHHHHCCCCCCCCCCEEEEEEEECCEECCCCEEECCCCCCCCCCCHHHHHH
DYVTALGIEQIAAYEHQLLEYGTEQLSGIPGLRLIGTAKEKASVLSFVIEGIHPHDIGTI
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCHHHHHHHHHHHHCCCCCHHHHH
LDKQGIAVRTGHHCAQPVMDFFNVPATTRASLAFYNTFGEIDALVGGLKKVKEIFS
HCCCCCEEECCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHC
>Mature Secondary Structure 
STLSSTPTAASFDVEKIREDFPVLKQKVHGKPLVYLDSAATAQKPLAVIDAIRRFHEVD
CCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCHHHHHHHHHHHHHCC
CANIHRGVHELSQRSTAAYEETRAKAKRFLNARSKDELIFVRGTTEGINLVTSSWGRRNV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCHHHHCCCCCCCC
KEGDEIIVSAMEHHSNIVPWQMLCLDTGANLRVIPMNERGELIMEEYEKLLNPRTKMVAV
CCHHHHHHHHHHHCCCCCCCEEEEEECCCCEEEEECCCCCCHHHHHHHHHHCCHHHEEEH
AHVSNALGTINPVRQIIEMAHNVGALTLIDGAQAVPHAKVDLQALDADFYTFSGHKIVGP
HHHHHHHCCHHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCCEEECCCEEEECCCEEECC
TGIGILYGKTKLLNAMPPYQGGGDMIKVVTFEKTTYADLPYKFEAGTPNIAGGIGLGAAL
CCCEEEECCHHHHHCCCCCCCCCCEEEEEEEECCEECCCCEEECCCCCCCCCCCHHHHHH
DYVTALGIEQIAAYEHQLLEYGTEQLSGIPGLRLIGTAKEKASVLSFVIEGIHPHDIGTI
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCHHHHHHHHHHHHCCCCCHHHHH
LDKQGIAVRTGHHCAQPVMDFFNVPATTRASLAFYNTFGEIDALVGGLKKVKEIFS
HCCCCCEEECCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA