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The map label for this gene is kdsB

Identifier: 116625271

GI number: 116625271

Start: 7794309

End: 7795067

Strand: Reverse

Name: kdsB

Synonym: Acid_6216

Alternate gene names: 116625271

Gene position: 7795067-7794309 (Counterclockwise)

Preceding gene: 116625276

Following gene: 116625270

Centisome position: 78.22

GC content: 57.44

Gene sequence:

>759_bases
GTGCCGCGTAAAATTCTCGGCGTCATCCCTGCTAGATTCTCCTCTACTCGATTTCCCGGCAAGGTTTTGGCTCAAATCGC
CAACAAAACCATGCTGCAGCACGTTTACGAGCGTGCCGGGCTCGCAACTTACCTCACGAGCACGATCATTGCCACGGATG
ACGAGCGCGTCTACACAGCTGCAAAAAGTTTCGGCGCACGGGTACGAATGACACGCGCCGACCACCTTTCAGGCACGGAC
CGCGTGGCCGAGGTGGCTTCCGCGGAGAACGCCGAAATCATCGTCAACATTCAAGGCGACGAGCCGTTGATCGATCCGGC
GGCGATCGATGCCGCTGTATTGCCGTTGGTGCATGAGCCCGACGTGCTCATGGGGACGCTCAAGAAGCGGATCGAAGATC
CGCGCGAAATCGTCGATCCCAACGTGGTTAAGGTTGTCACAGACCATGCGGGGGATGCGATCTATTTTTCCCGGTGCCCG
ATTCCGTTCGATCGCGACCGTTCCGCCGACACGCCCTATTTCAAGCATGTCGGGCTATACGTCTACCAGCGGGATTTCCT
GCTCTCCTATTCCACGCTGCCGGTAGGGCCGCTGGAACGGTCGGAGCGGCTGGAGCAGTTGCGTGCGTTGGAAAACGGAT
ATCGAATCCGGGTGGTGGAAACCGAATACGAGTCGTTGGGCGTGGATACGCCGGAGGATCTGGAAAGGGTGAGCAGATTG
TTCAAAGCCTCAATCTTACAAGGGATGGGAAATGGCTAA

Upstream 100 bases:

>100_bases
AATGGCGCTACGAATCAACAACTTAAGGTAGGACGGCAGCATCGGCTGGCCAGCCTTTCTTCCCCAAGAATAACATAAGG
ATTTTATGGTATGATCGCGT

Downstream 100 bases:

>100_bases
ATACATATTCGTAACCGGCGGCGTGGTCTCCTCTTTGGGGAAAGGGATTGCGGCCGCGTCGATCGGTTGCCTGCTGGAGA
GCCGCGGACTCAAAGTCACG

Product: 3-deoxy-manno-octulosonate cytidylyltransferase

Products: NA

Alternate protein names: CMP-2-keto-3-deoxyoctulosonic acid synthase; CKS; CMP-KDO synthase

Number of amino acids: Translated: 252; Mature: 251

Protein sequence:

>252_residues
MPRKILGVIPARFSSTRFPGKVLAQIANKTMLQHVYERAGLATYLTSTIIATDDERVYTAAKSFGARVRMTRADHLSGTD
RVAEVASAENAEIIVNIQGDEPLIDPAAIDAAVLPLVHEPDVLMGTLKKRIEDPREIVDPNVVKVVTDHAGDAIYFSRCP
IPFDRDRSADTPYFKHVGLYVYQRDFLLSYSTLPVGPLERSERLEQLRALENGYRIRVVETEYESLGVDTPEDLERVSRL
FKASILQGMGNG

Sequences:

>Translated_252_residues
MPRKILGVIPARFSSTRFPGKVLAQIANKTMLQHVYERAGLATYLTSTIIATDDERVYTAAKSFGARVRMTRADHLSGTD
RVAEVASAENAEIIVNIQGDEPLIDPAAIDAAVLPLVHEPDVLMGTLKKRIEDPREIVDPNVVKVVTDHAGDAIYFSRCP
IPFDRDRSADTPYFKHVGLYVYQRDFLLSYSTLPVGPLERSERLEQLRALENGYRIRVVETEYESLGVDTPEDLERVSRL
FKASILQGMGNG
>Mature_251_residues
PRKILGVIPARFSSTRFPGKVLAQIANKTMLQHVYERAGLATYLTSTIIATDDERVYTAAKSFGARVRMTRADHLSGTDR
VAEVASAENAEIIVNIQGDEPLIDPAAIDAAVLPLVHEPDVLMGTLKKRIEDPREIVDPNVVKVVTDHAGDAIYFSRCPI
PFDRDRSADTPYFKHVGLYVYQRDFLLSYSTLPVGPLERSERLEQLRALENGYRIRVVETEYESLGVDTPEDLERVSRLF
KASILQGMGNG

Specific function: Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria

COG id: COG1212

COG function: function code M; CMP-2-keto-3-deoxyoctulosonic acid synthetase

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the kdsB family

Homologues:

Organism=Escherichia coli, GI1787147, Length=240, Percent_Identity=46.6666666666667, Blast_Score=180, Evalue=1e-46,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): KDSB_SOLUE (Q01T78)

Other databases:

- EMBL:   CP000473
- RefSeq:   YP_827427.1
- ProteinModelPortal:   Q01T78
- SMR:   Q01T78
- STRING:   Q01T78
- GeneID:   4425552
- GenomeReviews:   CP000473_GR
- KEGG:   sus:Acid_6216
- NMPDR:   fig|234267.9.peg.5906
- eggNOG:   COG1212
- HOGENOM:   HBG637773
- OMA:   IIPARLK
- PhylomeDB:   Q01T78
- ProtClustDB:   PRK05450
- GO:   GO:0005737
- HAMAP:   MF_00057
- InterPro:   IPR003329
- InterPro:   IPR004528
- TIGRFAMs:   TIGR00466

Pfam domain/function: PF02348 CTP_transf_3

EC number: =2.7.7.38

Molecular weight: Translated: 28087; Mature: 27956

Theoretical pI: Translated: 5.71; Mature: 5.71

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPRKILGVIPARFSSTRFPGKVLAQIANKTMLQHVYERAGLATYLTSTIIATDDERVYTA
CCCCHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCHHHHH
AKSFGARVRMTRADHLSGTDRVAEVASAENAEIIVNIQGDEPLIDPAAIDAAVLPLVHEP
HHHHCCEEEEECHHCCCCHHHHHHHHCCCCCEEEEEECCCCCCCCHHHHHHHHHCCCCCC
DVLMGTLKKRIEDPREIVDPNVVKVVTDHAGDAIYFSRCPIPFDRDRSADTPYFKHVGLY
HHHHHHHHHHHCCCHHHHCCCEEEEEECCCCCEEEEECCCCCCCCCCCCCCCHHHHHHHH
VYQRDFLLSYSTLPVGPLERSERLEQLRALENGYRIRVVETEYESLGVDTPEDLERVSRL
EEEHHHHEEECCCCCCCCHHHHHHHHHHHHHCCCEEEEEEECHHHCCCCCHHHHHHHHHH
FKASILQGMGNG
HHHHHHHHCCCC
>Mature Secondary Structure 
PRKILGVIPARFSSTRFPGKVLAQIANKTMLQHVYERAGLATYLTSTIIATDDERVYTA
CCCHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCHHHHH
AKSFGARVRMTRADHLSGTDRVAEVASAENAEIIVNIQGDEPLIDPAAIDAAVLPLVHEP
HHHHCCEEEEECHHCCCCHHHHHHHHCCCCCEEEEEECCCCCCCCHHHHHHHHHCCCCCC
DVLMGTLKKRIEDPREIVDPNVVKVVTDHAGDAIYFSRCPIPFDRDRSADTPYFKHVGLY
HHHHHHHHHHHCCCHHHHCCCEEEEEECCCCCEEEEECCCCCCCCCCCCCCCHHHHHHHH
VYQRDFLLSYSTLPVGPLERSERLEQLRALENGYRIRVVETEYESLGVDTPEDLERVSRL
EEEHHHHEEECCCCCCCCHHHHHHHHHHHHHCCCEEEEEEECHHHCCCCCHHHHHHHHHH
FKASILQGMGNG
HHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA