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The map label for this gene is ctpA [H]

Identifier: 116625276

GI number: 116625276

Start: 7799963

End: 7801564

Strand: Reverse

Name: ctpA [H]

Synonym: Acid_6221

Alternate gene names: 116625276

Gene position: 7801564-7799963 (Counterclockwise)

Preceding gene: 116625277

Following gene: 116625271

Centisome position: 78.28

GC content: 60.49

Gene sequence:

>1602_bases
ATGGCCCGAAGAAGGCGCTCCCTCTTTGTCTTACCCGTGATTGTTTTCGCCTGCTCCATTGCAGGCGGGTTTTACGGGCC
GAAAGTGGAGGTAGCCGCGGCAGCCTCGCAATCCGAAGATCTCGATAAAGACGTACGGGACTTCAGCAAAGTCCTTTCCC
TGGTGCAAGATAACTTCGCGGACCACGTCAGCGCCGATAAGACGATCTACAAGGGCGCGATTCCCGGCATGCTGCGCACG
CTGGACCCGCACTCCAACTTTTTCGACGCGCGCGAGTACCAATTGATGCGCGAGGACCAGAAGGGCCACTACTACGGCGT
GGGCATGCAGGTATCGCCGCAACCCAGCGGGAAGACCGCGGTCAAGGCGCCGTTCCCCGGTTCACCGGCGTACAAAGTGG
GCCTGCGGCCGGGCGACCTCCTAATTTCGGTGAACGACAAGTCCACCGAAGGGCTGAACACCACCGAGATCGCCGACCTG
TTGAAGGGACCCCGCGGGACCTCGGTGAAGATCGTGGTGTCGCGGGAGGGAACGAAGGATTACCTGACCTTCACGGTGGT
GCGCGACGAGATCAGCCGTAAGAGTGTTCAGGATGCGTTCTGGATTAAGCCGGGTTATGCGTACGTGAAGATCCTGAGCT
TCGGCGAGAATACCAGCAGGGAACTGGAAGAGAACCTGAAGCGCCTGGGCGAGAACAATATCAAGGGGCTGGTGCTGGAC
CTGCGCGAGAATCCCGGTGGACTGTTGAATGAAGGCGTCGCGGTAGCGGACCACTTCCTGCCCAAGAATGCGCTGATTGT
TTCGCACCGCGGGCGCTCCGCTCCGGAAAAGGCTTACGTGGCGCAGCACGGCAATCGCGGACGCGATTACGCAATGGTGG
TGCTGGTCAACCGCTATTCGGCATCGGCCGCGGAGATCGTGTCGGGCGCGCTGCAGGATCACGATCGCGCGTTGATTCTG
GGCGAGACCACGTTCGGCAAGGGCCTGGTCCAGACGGTGTATCCGCTGAGCGACAATACGGCGCTGGCGTTGACCTGGGC
GCATTTCTATACGCCCAGCGGCCGGCTGATCCAGCGCGACTACTCGAATAAGAGCTTCTACGATTACTACACGCATCGCG
ACGAAAGCACGCGCAATCCGGTGGACGTGAAGATGACCGATGGCGGCCGCACGGTATATGGCGGCGGCGGCATTACTCCG
GACGAGAAGTACGAGGTGCCTAAGCTGGACCGTTTCGAGATCGGCCTCTTCCGCAACGGTCTGTTCGATTTCACGCGGTC
TTATTTCGGCGCGCATTCGGCGGCGAGCCTCTCCAAGACCTGGATGCCGGACGACCAGGTGCTCAACGAACTGAAGGCTC
ACCTGCGAAGCAAGGGCACGGTGTTCACGGATGCCGAGTTCAACAAGGATCGCGAGTGGATCAAGCGCAACCTGGCGCGC
GAGATGTATACCTCCGCATTCAATGTGGATGAAAGCGACGCGATGTTCGCGCGCACGGATCCCGAAGTGGAGAAGGCCGT
GGAGATGATGCCCAAGGCCGCGGCGCTGGCGGAGAGCGCGAAGAAGATCATCGTTCAGCGCATGGCAGGACAGGGACGCT
AA

Upstream 100 bases:

>100_bases
GTGCTGGACGCCGTGCGACGTGAAATGCCGGAGCCAAATGCTCCTCCGGCGCGTCTAAATTCCTAGTAAGGTATACTTCG
CTCTAAGGACGGTTTCCCGA

Downstream 100 bases:

>100_bases
AGGTCACCGGTCACCGGGTATCGTCACTGGCTATCCAGGTATCGGCGTCGCGCGGAGGGATCGATCGGACCTGTGATTCG
GGACTGCGGGCGGTACGACC

Product: carboxyl-terminal protease

Products: NA

Alternate protein names: C-terminal-processing protease [H]

Number of amino acids: Translated: 533; Mature: 532

Protein sequence:

>533_residues
MARRRRSLFVLPVIVFACSIAGGFYGPKVEVAAAASQSEDLDKDVRDFSKVLSLVQDNFADHVSADKTIYKGAIPGMLRT
LDPHSNFFDAREYQLMREDQKGHYYGVGMQVSPQPSGKTAVKAPFPGSPAYKVGLRPGDLLISVNDKSTEGLNTTEIADL
LKGPRGTSVKIVVSREGTKDYLTFTVVRDEISRKSVQDAFWIKPGYAYVKILSFGENTSRELEENLKRLGENNIKGLVLD
LRENPGGLLNEGVAVADHFLPKNALIVSHRGRSAPEKAYVAQHGNRGRDYAMVVLVNRYSASAAEIVSGALQDHDRALIL
GETTFGKGLVQTVYPLSDNTALALTWAHFYTPSGRLIQRDYSNKSFYDYYTHRDESTRNPVDVKMTDGGRTVYGGGGITP
DEKYEVPKLDRFEIGLFRNGLFDFTRSYFGAHSAASLSKTWMPDDQVLNELKAHLRSKGTVFTDAEFNKDREWIKRNLAR
EMYTSAFNVDESDAMFARTDPEVEKAVEMMPKAAALAESAKKIIVQRMAGQGR

Sequences:

>Translated_533_residues
MARRRRSLFVLPVIVFACSIAGGFYGPKVEVAAAASQSEDLDKDVRDFSKVLSLVQDNFADHVSADKTIYKGAIPGMLRT
LDPHSNFFDAREYQLMREDQKGHYYGVGMQVSPQPSGKTAVKAPFPGSPAYKVGLRPGDLLISVNDKSTEGLNTTEIADL
LKGPRGTSVKIVVSREGTKDYLTFTVVRDEISRKSVQDAFWIKPGYAYVKILSFGENTSRELEENLKRLGENNIKGLVLD
LRENPGGLLNEGVAVADHFLPKNALIVSHRGRSAPEKAYVAQHGNRGRDYAMVVLVNRYSASAAEIVSGALQDHDRALIL
GETTFGKGLVQTVYPLSDNTALALTWAHFYTPSGRLIQRDYSNKSFYDYYTHRDESTRNPVDVKMTDGGRTVYGGGGITP
DEKYEVPKLDRFEIGLFRNGLFDFTRSYFGAHSAASLSKTWMPDDQVLNELKAHLRSKGTVFTDAEFNKDREWIKRNLAR
EMYTSAFNVDESDAMFARTDPEVEKAVEMMPKAAALAESAKKIIVQRMAGQGR
>Mature_532_residues
ARRRRSLFVLPVIVFACSIAGGFYGPKVEVAAAASQSEDLDKDVRDFSKVLSLVQDNFADHVSADKTIYKGAIPGMLRTL
DPHSNFFDAREYQLMREDQKGHYYGVGMQVSPQPSGKTAVKAPFPGSPAYKVGLRPGDLLISVNDKSTEGLNTTEIADLL
KGPRGTSVKIVVSREGTKDYLTFTVVRDEISRKSVQDAFWIKPGYAYVKILSFGENTSRELEENLKRLGENNIKGLVLDL
RENPGGLLNEGVAVADHFLPKNALIVSHRGRSAPEKAYVAQHGNRGRDYAMVVLVNRYSASAAEIVSGALQDHDRALILG
ETTFGKGLVQTVYPLSDNTALALTWAHFYTPSGRLIQRDYSNKSFYDYYTHRDESTRNPVDVKMTDGGRTVYGGGGITPD
EKYEVPKLDRFEIGLFRNGLFDFTRSYFGAHSAASLSKTWMPDDQVLNELKAHLRSKGTVFTDAEFNKDREWIKRNLARE
MYTSAFNVDESDAMFARTDPEVEKAVEMMPKAAALAESAKKIIVQRMAGQGR

Specific function: Involved in protection of the bacterium from thermal and osmotic stresses (Potential) [H]

COG id: COG0793

COG function: function code M; Periplasmic protease

Gene ontology:

Cell location: Secreted (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PDZ (DHR) domain [H]

Homologues:

Organism=Escherichia coli, GI1788134, Length=281, Percent_Identity=29.5373665480427, Blast_Score=107, Evalue=2e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001478
- InterPro:   IPR005151
- InterPro:   IPR004447 [H]

Pfam domain/function: PF00595 PDZ; PF03572 Peptidase_S41 [H]

EC number: =3.4.21.102 [H]

Molecular weight: Translated: 59217; Mature: 59085

Theoretical pI: Translated: 8.88; Mature: 8.88

Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS50106 PDZ

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARRRRSLFVLPVIVFACSIAGGFYGPKVEVAAAASQSEDLDKDVRDFSKVLSLVQDNFA
CCCCCCCEEHHHHHHHHHHHHCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHH
DHVSADKTIYKGAIPGMLRTLDPHSNFFDAREYQLMREDQKGHYYGVGMQVSPQPSGKTA
HHCCCCCEEECCCCCHHHHHCCCCCCCCCHHHHHHHHHCCCCCEEEECEEECCCCCCCCE
VKAPFPGSPAYKVGLRPGDLLISVNDKSTEGLNTTEIADLLKGPRGTSVKIVVSREGTKD
EECCCCCCCCEEECCCCCCEEEEECCCCCCCCCHHHHHHHHCCCCCCEEEEEEECCCCCC
YLTFTVVRDEISRKSVQDAFWIKPGYAYVKILSFGENTSRELEENLKRLGENNIKGLVLD
EEEEEEEHHHHHHHHHHHHEEECCCCEEEEEEECCCCCHHHHHHHHHHHCCCCCCEEEEE
LRENPGGLLNEGVAVADHFLPKNALIVSHRGRSAPEKAYVAQHGNRGRDYAMVVLVNRYS
ECCCCCCCHHCCHHHHHHHCCCCEEEEECCCCCCCHHHHHHHCCCCCCCEEEEEEEECCC
ASAAEIVSGALQDHDRALILGETTFGKGLVQTVYPLSDNTALALTWAHFYTPSGRLIQRD
CHHHHHHHHHHHCCCCEEEEECCCCCCCHHHHEEECCCCCEEEEEEEEEECCCCCEEEEC
YSNKSFYDYYTHRDESTRNPVDVKMTDGGRTVYGGGGITPDEKYEVPKLDRFEIGLFRNG
CCCCCEEEHHHCCCCCCCCCEEEEECCCCEEEECCCCCCCCCCCCCCCCCCEEEHHHHHH
LFDFTRSYFGAHSAASLSKTWMPDDQVLNELKAHLRSKGTVFTDAEFNKDREWIKRNLAR
HHHHHHHHHCCCCHHHHHHCCCCHHHHHHHHHHHHHCCCCEEECCCCCCCHHHHHHHHHH
EMYTSAFNVDESDAMFARTDPEVEKAVEMMPKAAALAESAKKIIVQRMAGQGR
HHHHHHCCCCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
ARRRRSLFVLPVIVFACSIAGGFYGPKVEVAAAASQSEDLDKDVRDFSKVLSLVQDNFA
CCCCCCEEHHHHHHHHHHHHCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHH
DHVSADKTIYKGAIPGMLRTLDPHSNFFDAREYQLMREDQKGHYYGVGMQVSPQPSGKTA
HHCCCCCEEECCCCCHHHHHCCCCCCCCCHHHHHHHHHCCCCCEEEECEEECCCCCCCCE
VKAPFPGSPAYKVGLRPGDLLISVNDKSTEGLNTTEIADLLKGPRGTSVKIVVSREGTKD
EECCCCCCCCEEECCCCCCEEEEECCCCCCCCCHHHHHHHHCCCCCCEEEEEEECCCCCC
YLTFTVVRDEISRKSVQDAFWIKPGYAYVKILSFGENTSRELEENLKRLGENNIKGLVLD
EEEEEEEHHHHHHHHHHHHEEECCCCEEEEEEECCCCCHHHHHHHHHHHCCCCCCEEEEE
LRENPGGLLNEGVAVADHFLPKNALIVSHRGRSAPEKAYVAQHGNRGRDYAMVVLVNRYS
ECCCCCCCHHCCHHHHHHHCCCCEEEEECCCCCCCHHHHHHHCCCCCCCEEEEEEEECCC
ASAAEIVSGALQDHDRALILGETTFGKGLVQTVYPLSDNTALALTWAHFYTPSGRLIQRD
CHHHHHHHHHHHCCCCEEEEECCCCCCCHHHHEEECCCCCEEEEEEEEEECCCCCEEEEC
YSNKSFYDYYTHRDESTRNPVDVKMTDGGRTVYGGGGITPDEKYEVPKLDRFEIGLFRNG
CCCCCEEEHHHCCCCCCCCCEEEEECCCCEEEECCCCCCCCCCCCCCCCCCEEEHHHHHH
LFDFTRSYFGAHSAASLSKTWMPDDQVLNELKAHLRSKGTVFTDAEFNKDREWIKRNLAR
HHHHHHHHHCCCCHHHHHHCCCCHHHHHHHHHHHHHCCCCEEECCCCCCCHHHHHHHHHH
EMYTSAFNVDESDAMFARTDPEVEKAVEMMPKAAALAESAKKIIVQRMAGQGR
HHHHHHCCCCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9141685 [H]