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The map label for this gene is yutK [H]

Identifier: 116624314

GI number: 116624314

Start: 6566725

End: 6567948

Strand: Direct

Name: yutK [H]

Synonym: Acid_5232

Alternate gene names: 116624314

Gene position: 6566725-6567948 (Clockwise)

Preceding gene: 116624313

Following gene: 116624315

Centisome position: 65.89

GC content: 61.44

Gene sequence:

>1224_bases
ATGGAGCGTTTCACGGGGTTGCTGGGCCTCGTCGTGATCCTGGCAGTCGCGTGGTTGTTTTCCACTCACAAACGCGAGAT
CAAGCTACGGTTGATCGCGTGGGGCATGGGGCTACAGATCCTCTTCGCAGTGCTGGTGCTGAAGACGGATTTCGGCATCA
TCTTCCAGCGCATCGGCGACGGCGTGAACGCGATGCTGAACTATGCCGAAGTCGGCAGCCAGTTTCTATTCGGACCGCTG
GGCACGAAGGCGGGGCCGTATGGCGTGCTGTTCGCCTTCCAGGTGCTGCCGATCGTGATCTTCATCGCGTCGTTTTTCTC
CATCCTTTATTACCTCGGCGTGATGCAGTTCGTGGTCAAGGCGATGGCGATCGGGATGCAGAAGGTGATGGGGGTGAGCG
GCGCCGAGAGTTTGAACGTGGCGGCGAGCATCTTCATGGGGCAGACCGAAGCGCCGCTGACGATCAAGCCGTTCCTGGCG
GGGCTGACGGAATCCGAATTGTTCACGATCATGACGGCCGGCATGGCGCACGTATCGGGCGCGGTGATGGCGGCATACGT
GAAGATAGCGGGAGTTTCGATCACGCATTTGCTGACCGCGGTAATTATGACGGCGCCGGCGACGATCATGCTGGCCAAGA
TTTTCATTCCGGAAACGGAAAAGCCGGCGACCGCGGGACGCGTGGACGTGAAGATCGAGAAGACCGCGGTCAACGTGATC
GACGCAGCGGCACAGGGAGCGGGCGACGGGTTGCAACTGGCGCTGAACATCGGCGGCATGCTGATCGCGTTCCTGGCATT
GATCGCGATGGTCAACGGAATTCTGGGCTGGGTGCACACGTTGCCCCTGATGGGCTGGCTGCCCTCGTCCCTGGAGCGCG
TGTTTGGCATTCTGTTCGCGCCGGTGGCGTGGCTGCTGGGCGTGCCGTGGAAGGACTGCGGCGTGATCGGCGACCTGCTG
GGCACGCGGCTGGTGCTCAATGAATTCGTGTCGTTCCTGAAATTGGGGCCGCTGAAGGCGTCGCTCGATCCGAAGAGCTT
TACGATTGCGACGTACGCGTTGTGCGGATTTGCGAATTTCAGTTCGATCGCGATTCAGATCGGCGGCATCGGAGCGCTGG
CGCCGACGCGCAAGAGCGACCTGGCGAGGCTGGGACTGCGCGCGGTGGCGGCGGGGACGATGGCGAACTTCATGTCGGCG
TGCATTGCGGGAATGTTGCTGTGA

Upstream 100 bases:

>100_bases
AAGACAACGTGGACGAGGCCGCCGAAATGGTGGAGGATGCCTTCCGCGTGTCCGGCACCAAGCCTGATGAGCGCGAGCTC
ATCCTGGAAGTTGTCGGCTA

Downstream 100 bases:

>100_bases
CGGACGAGGCAAAGCGGTTTATTCAAGGCCACACGAGTGTGCGGCCGTCCATCGGCGTCGTGTTGGGGAGCGGGCTTGGG
GCGTTTGCCGACGAGCTCAC

Product: Na+ dependent nucleoside transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 407; Mature: 407

Protein sequence:

>407_residues
MERFTGLLGLVVILAVAWLFSTHKREIKLRLIAWGMGLQILFAVLVLKTDFGIIFQRIGDGVNAMLNYAEVGSQFLFGPL
GTKAGPYGVLFAFQVLPIVIFIASFFSILYYLGVMQFVVKAMAIGMQKVMGVSGAESLNVAASIFMGQTEAPLTIKPFLA
GLTESELFTIMTAGMAHVSGAVMAAYVKIAGVSITHLLTAVIMTAPATIMLAKIFIPETEKPATAGRVDVKIEKTAVNVI
DAAAQGAGDGLQLALNIGGMLIAFLALIAMVNGILGWVHTLPLMGWLPSSLERVFGILFAPVAWLLGVPWKDCGVIGDLL
GTRLVLNEFVSFLKLGPLKASLDPKSFTIATYALCGFANFSSIAIQIGGIGALAPTRKSDLARLGLRAVAAGTMANFMSA
CIAGMLL

Sequences:

>Translated_407_residues
MERFTGLLGLVVILAVAWLFSTHKREIKLRLIAWGMGLQILFAVLVLKTDFGIIFQRIGDGVNAMLNYAEVGSQFLFGPL
GTKAGPYGVLFAFQVLPIVIFIASFFSILYYLGVMQFVVKAMAIGMQKVMGVSGAESLNVAASIFMGQTEAPLTIKPFLA
GLTESELFTIMTAGMAHVSGAVMAAYVKIAGVSITHLLTAVIMTAPATIMLAKIFIPETEKPATAGRVDVKIEKTAVNVI
DAAAQGAGDGLQLALNIGGMLIAFLALIAMVNGILGWVHTLPLMGWLPSSLERVFGILFAPVAWLLGVPWKDCGVIGDLL
GTRLVLNEFVSFLKLGPLKASLDPKSFTIATYALCGFANFSSIAIQIGGIGALAPTRKSDLARLGLRAVAAGTMANFMSA
CIAGMLL
>Mature_407_residues
MERFTGLLGLVVILAVAWLFSTHKREIKLRLIAWGMGLQILFAVLVLKTDFGIIFQRIGDGVNAMLNYAEVGSQFLFGPL
GTKAGPYGVLFAFQVLPIVIFIASFFSILYYLGVMQFVVKAMAIGMQKVMGVSGAESLNVAASIFMGQTEAPLTIKPFLA
GLTESELFTIMTAGMAHVSGAVMAAYVKIAGVSITHLLTAVIMTAPATIMLAKIFIPETEKPATAGRVDVKIEKTAVNVI
DAAAQGAGDGLQLALNIGGMLIAFLALIAMVNGILGWVHTLPLMGWLPSSLERVFGILFAPVAWLLGVPWKDCGVIGDLL
GTRLVLNEFVSFLKLGPLKASLDPKSFTIATYALCGFANFSSIAIQIGGIGALAPTRKSDLARLGLRAVAAGTMANFMSA
CIAGMLL

Specific function: Unknown

COG id: COG1972

COG function: function code F; Nucleoside permease

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family [H]

Homologues:

Organism=Homo sapiens, GI42542381, Length=422, Percent_Identity=37.6777251184834, Blast_Score=286, Evalue=2e-77,
Organism=Homo sapiens, GI11545853, Length=415, Percent_Identity=40.2409638554217, Blast_Score=278, Evalue=7e-75,
Organism=Homo sapiens, GI227116277, Length=422, Percent_Identity=36.7298578199052, Blast_Score=276, Evalue=2e-74,
Organism=Escherichia coli, GI1788485, Length=419, Percent_Identity=37.9474940334129, Blast_Score=271, Evalue=4e-74,
Organism=Escherichia coli, GI1788488, Length=420, Percent_Identity=37.8571428571429, Blast_Score=259, Evalue=3e-70,
Organism=Escherichia coli, GI1788737, Length=411, Percent_Identity=27.007299270073, Blast_Score=164, Evalue=8e-42,
Organism=Caenorhabditis elegans, GI17560276, Length=416, Percent_Identity=34.375, Blast_Score=218, Evalue=6e-57,
Organism=Caenorhabditis elegans, GI71991794, Length=417, Percent_Identity=31.6546762589928, Blast_Score=214, Evalue=6e-56,
Organism=Caenorhabditis elegans, GI25146537, Length=215, Percent_Identity=31.1627906976744, Blast_Score=115, Evalue=6e-26,
Organism=Drosophila melanogaster, GI45552519, Length=410, Percent_Identity=37.0731707317073, Blast_Score=273, Evalue=1e-73,
Organism=Drosophila melanogaster, GI45552517, Length=410, Percent_Identity=37.0731707317073, Blast_Score=273, Evalue=1e-73,
Organism=Drosophila melanogaster, GI19921868, Length=410, Percent_Identity=37.0731707317073, Blast_Score=273, Evalue=1e-73,
Organism=Drosophila melanogaster, GI281360430, Length=406, Percent_Identity=38.423645320197, Blast_Score=252, Evalue=3e-67,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008276
- InterPro:   IPR018270
- InterPro:   IPR011642
- InterPro:   IPR011657
- InterPro:   IPR002668 [H]

Pfam domain/function: PF07670 Gate; PF07662 Nucleos_tra2_C; PF01773 Nucleos_tra2_N [H]

EC number: NA

Molecular weight: Translated: 43037; Mature: 43037

Theoretical pI: Translated: 9.57; Mature: 9.57

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
4.7 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
4.7 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MERFTGLLGLVVILAVAWLFSTHKREIKLRLIAWGMGLQILFAVLVLKTDFGIIFQRIGD
CCHHHHHHHHHHHHHHHHHHHCCCHHEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHCC
GVNAMLNYAEVGSQFLFGPLGTKAGPYGVLFAFQVLPIVIFIASFFSILYYLGVMQFVVK
HHHHHHHHHHHCCHHEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AMAIGMQKVMGVSGAESLNVAASIFMGQTEAPLTIKPFLAGLTESELFTIMTAGMAHVSG
HHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCEEHHHHHHCCCHHHHHHHHHHHHHHHHH
AVMAAYVKIAGVSITHLLTAVIMTAPATIMLAKIFIPETEKPATAGRVDVKIEKTAVNVI
HHHHHHHHHHCCHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCCCCEEEEEEHHHHHHH
DAAAQGAGDGLQLALNIGGMLIAFLALIAMVNGILGWVHTLPLMGWLPSSLERVFGILFA
HHHHCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHH
PVAWLLGVPWKDCGVIGDLLGTRLVLNEFVSFLKLGPLKASLDPKSFTIATYALCGFANF
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCC
SSIAIQIGGIGALAPTRKSDLARLGLRAVAAGTMANFMSACIAGMLL
CEEEEEECCEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MERFTGLLGLVVILAVAWLFSTHKREIKLRLIAWGMGLQILFAVLVLKTDFGIIFQRIGD
CCHHHHHHHHHHHHHHHHHHHCCCHHEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHCC
GVNAMLNYAEVGSQFLFGPLGTKAGPYGVLFAFQVLPIVIFIASFFSILYYLGVMQFVVK
HHHHHHHHHHHCCHHEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AMAIGMQKVMGVSGAESLNVAASIFMGQTEAPLTIKPFLAGLTESELFTIMTAGMAHVSG
HHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCEEHHHHHHCCCHHHHHHHHHHHHHHHHH
AVMAAYVKIAGVSITHLLTAVIMTAPATIMLAKIFIPETEKPATAGRVDVKIEKTAVNVI
HHHHHHHHHHCCHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCCCCEEEEEEHHHHHHH
DAAAQGAGDGLQLALNIGGMLIAFLALIAMVNGILGWVHTLPLMGWLPSSLERVFGILFA
HHHHCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHH
PVAWLLGVPWKDCGVIGDLLGTRLVLNEFVSFLKLGPLKASLDPKSFTIATYALCGFANF
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCC
SSIAIQIGGIGALAPTRKSDLARLGLRAVAAGTMANFMSACIAGMLL
CEEEEEECCEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]