BacMap

Definition	Candidatus Solibacter usitatus Ellin6076 chromosome, complete genome.
Accession	NC_008536
Length	9,965,640

Click here to switch to the map view.

The map label for this gene is ppiB [H]

Identifier: 116623916

GI number: 116623916

Start: 6099002

End: 6099490

Strand: Direct

Name: ppiB [H]

Synonym: Acid_4828

Alternate gene names: 116623916

Gene position: 6099002-6099490 (Clockwise)

Preceding gene: 116623914

Following gene: 116623917

Centisome position: 61.2

GC content: 59.92

Gene sequence:

>489_bases
ATGGCCAACGAAATCTACGCCGCTTTCGACACTAGCGAAGGCAAGTTTAAAGTCAAACTCTTCGCGGACAAAGCGCCCAA
CACGGTGAACAACTTTGTCTCGCTCGCCGATGGATCCAAGACCGGAAAGCCCTTCTACAACGGCACCATCTTCCATCGCG
TGATCCCCGACTTCATGATCCAGGGCGGCTGCCCCCAGGGCACCGGCACCGGCGGTCCCGGCTACAAGTTCGCAGATGAG
TTCCACCCCACCCTGAAGCACTCCAAGCCCGGCCTTCTTTCCATGGCCAACGCCGGACCCGGCACCAACGGCAGCCAGTT
TTTCGTGACCGTGGCCGCCACCCCCTGGCTGGATAACAAGCACAGCATCTTCGGCGAGGTGACCGAAGGCTACGACGTGG
TGGAGAAGATCTCGAAGGTCCCTCGCGGCGGCCAGGATCGCCCTGTCAAAGAAGTGCGGCTCAACTCCGTCACCATCGAG
AAGACATAG

Upstream 100 bases:

>100_bases
GGAGATTCTCCCGGAGCGTTACCAGGCAGTGCTTCGGGCGACTCAAACGGTCGCATCGTGAACTCAAGTCTACCATAGCC
ATGCTGTTACAATTCTAAGG

Downstream 100 bases:

>100_bases
CCGCGGGCGCCGTGAAACTGGCGATCTTCGGCGGCACCTTCGATCCGATTCACGCGGGCCACCTTGCGGCGGCCCGCGAA
GCTTCCACGCGATTTGCTCT

Product: peptidylprolyl isomerase

Products: NA

Alternate protein names: PPIase; Rotamase [H]

Number of amino acids: Translated: 162; Mature: 161

Protein sequence:

>162_residues
MANEIYAAFDTSEGKFKVKLFADKAPNTVNNFVSLADGSKTGKPFYNGTIFHRVIPDFMIQGGCPQGTGTGGPGYKFADE
FHPTLKHSKPGLLSMANAGPGTNGSQFFVTVAATPWLDNKHSIFGEVTEGYDVVEKISKVPRGGQDRPVKEVRLNSVTIE
KT

Sequences:

>Translated_162_residues
MANEIYAAFDTSEGKFKVKLFADKAPNTVNNFVSLADGSKTGKPFYNGTIFHRVIPDFMIQGGCPQGTGTGGPGYKFADE
FHPTLKHSKPGLLSMANAGPGTNGSQFFVTVAATPWLDNKHSIFGEVTEGYDVVEKISKVPRGGQDRPVKEVRLNSVTIE
KT
>Mature_161_residues
ANEIYAAFDTSEGKFKVKLFADKAPNTVNNFVSLADGSKTGKPFYNGTIFHRVIPDFMIQGGCPQGTGTGGPGYKFADEF
HPTLKHSKPGLLSMANAGPGTNGSQFFVTVAATPWLDNKHSIFGEVTEGYDVVEKISKVPRGGQDRPVKEVRLNSVTIEK
T

Specific function: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides [H]

COG id: COG0652

COG function: function code O; Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PPIase cyclophilin-type domain [H]

Homologues:

Organism=Homo sapiens, GI7706339, Length=149, Percent_Identity=51.6778523489933, Blast_Score=151, Evalue=3e-37,
Organism=Homo sapiens, GI24308049, Length=158, Percent_Identity=50.6329113924051, Blast_Score=150, Evalue=5e-37,
Organism=Homo sapiens, GI19557636, Length=158, Percent_Identity=41.1392405063291, Blast_Score=128, Evalue=2e-30,
Organism=Homo sapiens, GI4758950, Length=147, Percent_Identity=49.6598639455782, Blast_Score=127, Evalue=4e-30,
Organism=Homo sapiens, GI5454154, Length=145, Percent_Identity=50.3448275862069, Blast_Score=127, Evalue=6e-30,
Organism=Homo sapiens, GI10863927, Length=130, Percent_Identity=52.3076923076923, Blast_Score=125, Evalue=2e-29,
Organism=Homo sapiens, GI22547212, Length=158, Percent_Identity=44.9367088607595, Blast_Score=120, Evalue=5e-28,
Organism=Homo sapiens, GI7657473, Length=158, Percent_Identity=44.9367088607595, Blast_Score=120, Evalue=5e-28,
Organism=Homo sapiens, GI22547215, Length=158, Percent_Identity=44.9367088607595, Blast_Score=120, Evalue=6e-28,
Organism=Homo sapiens, GI4505991, Length=149, Percent_Identity=48.3221476510067, Blast_Score=119, Evalue=1e-27,
Organism=Homo sapiens, GI256017253, Length=126, Percent_Identity=52.3809523809524, Blast_Score=119, Evalue=1e-27,
Organism=Homo sapiens, GI221139811, Length=126, Percent_Identity=52.3809523809524, Blast_Score=119, Evalue=1e-27,
Organism=Homo sapiens, GI256017251, Length=126, Percent_Identity=52.3809523809524, Blast_Score=119, Evalue=1e-27,
Organism=Homo sapiens, GI45439316, Length=130, Percent_Identity=51.5384615384615, Blast_Score=117, Evalue=4e-27,
Organism=Homo sapiens, GI303305009, Length=132, Percent_Identity=50.7575757575758, Blast_Score=117, Evalue=4e-27,
Organism=Homo sapiens, GI64276486, Length=154, Percent_Identity=40.2597402597403, Blast_Score=117, Evalue=6e-27,
Organism=Homo sapiens, GI5031987, Length=128, Percent_Identity=53.125, Blast_Score=117, Evalue=6e-27,
Organism=Homo sapiens, GI178057341, Length=128, Percent_Identity=50.78125, Blast_Score=116, Evalue=8e-27,
Organism=Homo sapiens, GI310129267, Length=128, Percent_Identity=51.5625, Blast_Score=116, Evalue=8e-27,
Organism=Homo sapiens, GI310120620, Length=128, Percent_Identity=51.5625, Blast_Score=116, Evalue=8e-27,
Organism=Homo sapiens, GI310127646, Length=136, Percent_Identity=47.7941176470588, Blast_Score=115, Evalue=1e-26,
Organism=Homo sapiens, GI310114371, Length=136, Percent_Identity=47.7941176470588, Blast_Score=115, Evalue=1e-26,
Organism=Homo sapiens, GI310119221, Length=136, Percent_Identity=47.7941176470588, Blast_Score=115, Evalue=1e-26,
Organism=Homo sapiens, GI5174637, Length=129, Percent_Identity=51.1627906976744, Blast_Score=115, Evalue=2e-26,
Organism=Homo sapiens, GI310110104, Length=128, Percent_Identity=50.78125, Blast_Score=114, Evalue=3e-26,
Organism=Homo sapiens, GI209417936, Length=128, Percent_Identity=50, Blast_Score=114, Evalue=3e-26,
Organism=Homo sapiens, GI30102944, Length=128, Percent_Identity=50, Blast_Score=114, Evalue=3e-26,
Organism=Homo sapiens, GI219842199, Length=128, Percent_Identity=50, Blast_Score=114, Evalue=3e-26,
Organism=Homo sapiens, GI4826932, Length=148, Percent_Identity=48.6486486486487, Blast_Score=114, Evalue=4e-26,
Organism=Homo sapiens, GI6631100, Length=151, Percent_Identity=44.3708609271523, Blast_Score=111, Evalue=2e-25,
Organism=Homo sapiens, GI169164185, Length=128, Percent_Identity=49.21875, Blast_Score=110, Evalue=4e-25,
Organism=Homo sapiens, GI169163623, Length=128, Percent_Identity=49.21875, Blast_Score=110, Evalue=4e-25,
Organism=Homo sapiens, GI169163387, Length=128, Percent_Identity=49.21875, Blast_Score=110, Evalue=6e-25,
Organism=Homo sapiens, GI42560244, Length=153, Percent_Identity=44.4444444444444, Blast_Score=107, Evalue=4e-24,
Organism=Homo sapiens, GI310132444, Length=130, Percent_Identity=47.6923076923077, Blast_Score=104, Evalue=3e-23,
Organism=Homo sapiens, GI310113152, Length=130, Percent_Identity=47.6923076923077, Blast_Score=104, Evalue=3e-23,
Organism=Homo sapiens, GI150418007, Length=142, Percent_Identity=46.4788732394366, Blast_Score=103, Evalue=1e-22,
Organism=Homo sapiens, GI169214050, Length=137, Percent_Identity=45.985401459854, Blast_Score=100, Evalue=6e-22,
Organism=Homo sapiens, GI239751853, Length=137, Percent_Identity=45.985401459854, Blast_Score=100, Evalue=7e-22,
Organism=Homo sapiens, GI113428306, Length=137, Percent_Identity=45.985401459854, Blast_Score=100, Evalue=7e-22,
Organism=Homo sapiens, GI310127745, Length=121, Percent_Identity=48.7603305785124, Blast_Score=98, Evalue=3e-21,
Organism=Homo sapiens, GI310119290, Length=121, Percent_Identity=48.7603305785124, Blast_Score=98, Evalue=3e-21,
Organism=Homo sapiens, GI310114540, Length=121, Percent_Identity=48.7603305785124, Blast_Score=98, Evalue=3e-21,
Organism=Homo sapiens, GI20911035, Length=162, Percent_Identity=33.9506172839506, Blast_Score=94, Evalue=7e-20,
Organism=Homo sapiens, GI27735045, Length=150, Percent_Identity=38, Blast_Score=92, Evalue=2e-19,
Organism=Homo sapiens, GI289803023, Length=176, Percent_Identity=31.8181818181818, Blast_Score=84, Evalue=7e-17,
Organism=Homo sapiens, GI14277126, Length=96, Percent_Identity=43.75, Blast_Score=82, Evalue=2e-16,
Organism=Escherichia coli, GI1786736, Length=169, Percent_Identity=37.2781065088757, Blast_Score=84, Evalue=4e-18,
Organism=Escherichia coli, GI1789763, Length=165, Percent_Identity=35.1515151515151, Blast_Score=79, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17539496, Length=152, Percent_Identity=51.3157894736842, Blast_Score=154, Evalue=3e-38,
Organism=Caenorhabditis elegans, GI17506311, Length=161, Percent_Identity=49.0683229813665, Blast_Score=140, Evalue=2e-34,
Organism=Caenorhabditis elegans, GI17552780, Length=143, Percent_Identity=51.7482517482517, Blast_Score=134, Evalue=2e-32,
Organism=Caenorhabditis elegans, GI71980594, Length=153, Percent_Identity=41.8300653594771, Blast_Score=127, Evalue=2e-30,
Organism=Caenorhabditis elegans, GI17506307, Length=143, Percent_Identity=51.0489510489511, Blast_Score=126, Evalue=6e-30,
Organism=Caenorhabditis elegans, GI17559074, Length=153, Percent_Identity=47.7124183006536, Blast_Score=123, Evalue=3e-29,
Organism=Caenorhabditis elegans, GI17566266, Length=133, Percent_Identity=51.1278195488722, Blast_Score=122, Evalue=6e-29,
Organism=Caenorhabditis elegans, GI17565860, Length=136, Percent_Identity=50.7352941176471, Blast_Score=122, Evalue=1e-28,
Organism=Caenorhabditis elegans, GI71980590, Length=142, Percent_Identity=42.9577464788732, Blast_Score=121, Evalue=2e-28,
Organism=Caenorhabditis elegans, GI17551282, Length=150, Percent_Identity=47.3333333333333, Blast_Score=119, Evalue=8e-28,
Organism=Caenorhabditis elegans, GI17551284, Length=150, Percent_Identity=47.3333333333333, Blast_Score=119, Evalue=9e-28,
Organism=Caenorhabditis elegans, GI17532643, Length=143, Percent_Identity=51.0489510489511, Blast_Score=118, Evalue=1e-27,
Organism=Caenorhabditis elegans, GI17539498, Length=154, Percent_Identity=44.1558441558442, Blast_Score=116, Evalue=4e-27,
Organism=Caenorhabditis elegans, GI17552784, Length=153, Percent_Identity=38.562091503268, Blast_Score=112, Evalue=1e-25,
Organism=Caenorhabditis elegans, GI71997782, Length=148, Percent_Identity=41.8918918918919, Blast_Score=110, Evalue=3e-25,
Organism=Caenorhabditis elegans, GI17532641, Length=146, Percent_Identity=42.4657534246575, Blast_Score=110, Evalue=4e-25,
Organism=Caenorhabditis elegans, GI17552782, Length=142, Percent_Identity=46.4788732394366, Blast_Score=109, Evalue=7e-25,
Organism=Caenorhabditis elegans, GI32563659, Length=162, Percent_Identity=32.0987654320988, Blast_Score=97, Evalue=5e-21,
Organism=Caenorhabditis elegans, GI115533296, Length=136, Percent_Identity=36.7647058823529, Blast_Score=79, Evalue=8e-16,
Organism=Caenorhabditis elegans, GI32563661, Length=90, Percent_Identity=35.5555555555556, Blast_Score=71, Evalue=3e-13,
Organism=Saccharomyces cerevisiae, GI6320359, Length=131, Percent_Identity=53.4351145038168, Blast_Score=126, Evalue=2e-30,
Organism=Saccharomyces cerevisiae, GI6323562, Length=131, Percent_Identity=53.4351145038168, Blast_Score=122, Evalue=2e-29,
Organism=Saccharomyces cerevisiae, GI6320510, Length=147, Percent_Identity=48.9795918367347, Blast_Score=122, Evalue=2e-29,
Organism=Saccharomyces cerevisiae, GI6321848, Length=146, Percent_Identity=45.8904109589041, Blast_Score=118, Evalue=3e-28,
Organism=Saccharomyces cerevisiae, GI6323246, Length=159, Percent_Identity=42.7672955974843, Blast_Score=114, Evalue=7e-27,
Organism=Saccharomyces cerevisiae, GI6319914, Length=164, Percent_Identity=34.1463414634146, Blast_Score=66, Evalue=3e-12,
Organism=Drosophila melanogaster, GI17986117, Length=159, Percent_Identity=49.0566037735849, Blast_Score=157, Evalue=3e-39,
Organism=Drosophila melanogaster, GI19922376, Length=158, Percent_Identity=41.1392405063291, Blast_Score=136, Evalue=7e-33,
Organism=Drosophila melanogaster, GI19922912, Length=165, Percent_Identity=47.2727272727273, Blast_Score=124, Evalue=2e-29,
Organism=Drosophila melanogaster, GI45549139, Length=128, Percent_Identity=53.90625, Blast_Score=124, Evalue=3e-29,
Organism=Drosophila melanogaster, GI20130249, Length=151, Percent_Identity=47.682119205298, Blast_Score=122, Evalue=1e-28,
Organism=Drosophila melanogaster, GI24652460, Length=154, Percent_Identity=40.9090909090909, Blast_Score=121, Evalue=2e-28,
Organism=Drosophila melanogaster, GI24586038, Length=145, Percent_Identity=48.9655172413793, Blast_Score=116, Evalue=6e-27,
Organism=Drosophila melanogaster, GI24664125, Length=137, Percent_Identity=49.6350364963504, Blast_Score=115, Evalue=1e-26,
Organism=Drosophila melanogaster, GI21357783, Length=137, Percent_Identity=49.6350364963504, Blast_Score=115, Evalue=1e-26,
Organism=Drosophila melanogaster, GI24650807, Length=148, Percent_Identity=45.2702702702703, Blast_Score=112, Evalue=1e-25,
Organism=Drosophila melanogaster, GI21357249, Length=155, Percent_Identity=39.3548387096774, Blast_Score=108, Evalue=1e-24,
Organism=Drosophila melanogaster, GI17647301, Length=131, Percent_Identity=47.3282442748092, Blast_Score=105, Evalue=1e-23,
Organism=Drosophila melanogaster, GI17136360, Length=149, Percent_Identity=40.9395973154362, Blast_Score=101, Evalue=2e-22,
Organism=Drosophila melanogaster, GI21355677, Length=161, Percent_Identity=32.9192546583851, Blast_Score=87, Evalue=7e-18,
Organism=Drosophila melanogaster, GI24661775, Length=136, Percent_Identity=33.8235294117647, Blast_Score=67, Evalue=6e-12,
Organism=Drosophila melanogaster, GI21355237, Length=136, Percent_Identity=33.8235294117647, Blast_Score=67, Evalue=6e-12,
Organism=Drosophila melanogaster, GI24661771, Length=136, Percent_Identity=33.8235294117647, Blast_Score=67, Evalue=6e-12,

Paralogues:

None

Copy number: 780 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 60 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015891
- InterPro:   IPR020892
- InterPro:   IPR002130 [H]

Pfam domain/function: PF00160 Pro_isomerase [H]

EC number: =5.2.1.8 [H]

Molecular weight: Translated: 17486; Mature: 17355

Theoretical pI: Translated: 9.01; Mature: 9.01

Prosite motif: PS00170 CSA_PPIASE_1 ; PS50072 CSA_PPIASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MANEIYAAFDTSEGKFKVKLFADKAPNTVNNFVSLADGSKTGKPFYNGTIFHRVIPDFMI
CCCCEEEEEECCCCEEEEEEEECCCCCHHHHHEECCCCCCCCCCCCCCEEHHHHHHHHHH
QGGCPQGTGTGGPGYKFADEFHPTLKHSKPGLLSMANAGPGTNGSQFFVTVAATPWLDNK
CCCCCCCCCCCCCCCCCCCCCCCHHHCCCCCEEEECCCCCCCCCCEEEEEEEECCCCCCC
HSIFGEVTEGYDVVEKISKVPRGGQDRPVKEVRLNSVTIEKT
CCCCCCCCCCHHHHHHHHHCCCCCCCCCHHHEEECEEEEECC
>Mature Secondary Structure 
ANEIYAAFDTSEGKFKVKLFADKAPNTVNNFVSLADGSKTGKPFYNGTIFHRVIPDFMI
CCCEEEEEECCCCEEEEEEEECCCCCHHHHHEECCCCCCCCCCCCCCEEHHHHHHHHHH
QGGCPQGTGTGGPGYKFADEFHPTLKHSKPGLLSMANAGPGTNGSQFFVTVAATPWLDNK
CCCCCCCCCCCCCCCCCCCCCCCHHHCCCCCEEEECCCCCCCCCCEEEEEEEECCCCCCC
HSIFGEVTEGYDVVEKISKVPRGGQDRPVKEVRLNSVTIEKT
CCCCCCCCCCHHHHHHHHHCCCCCCCCCHHHEEECEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9317025; 9665876 [H]