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The map label for this gene is nadD

Identifier: 116623917

GI number: 116623917

Start: 6099502

End: 6100068

Strand: Direct

Name: nadD

Synonym: Acid_4829

Alternate gene names: 116623917

Gene position: 6099502-6100068 (Clockwise)

Preceding gene: 116623916

Following gene: 116623918

Centisome position: 61.21

GC content: 66.84

Gene sequence:

>567_bases
GTGAAACTGGCGATCTTCGGCGGCACCTTCGATCCGATTCACGCGGGCCACCTTGCGGCGGCCCGCGAAGCTTCCACGCG
ATTTGCTCTGGATCGCGTCCTCTTTATCCCCGCCGCGCACCCACCGCACAAAGCGGGGGTCACGCATGCCCCCTATGACG
ACCGCGTCCGCATGGCGGAACTTGCCTGCCGCGACGACGCGCGCTTCGAGGTCTCGCGGCTGGAGGAAGGCACCGCGCGC
AGCTACTCCATCGACACTATCGAGAAGGTGCGCGCCATGCTCGCACCCGGCGACGGGTTGTACTTTCTGATCGGCGCCGA
CGCCTTCGCCGAAATCCGCACCTGGCGCCGCTGGACGGATGTAGCTCGCGCCGTCCGCTTCCTGGTGGTCAGCCGTCCCG
GCCACACCTACGAGATTCCCGCAGAAGTCACGGTGGACCGCATCGACAGCCTGGAGATCCCCATCTCTTCTTCGGAGATC
CGCCGCACCCTGGCCGCCGGGGGCATACCTGAAGGTCTCCCGCCCGCCGTCCTCGCCTACGCCCGCGACCATCACCTCTA
CAACTGA

Upstream 100 bases:

>100_bases
TGGAGAAGATCTCGAAGGTCCCTCGCGGCGGCCAGGATCGCCCTGTCAAAGAAGTGCGGCTCAACTCCGTCACCATCGAG
AAGACATAGCCGCGGGCGCC

Downstream 100 bases:

>100_bases
TTTGCTGTACTATCTTGTACATAAAACAAATCAGGTTCAGAATGTTTGAGAGTGAGGTTTTGAATTGAAGCACACTTCCC
GCTACGGCACGCTCGCCTTG

Product: nicotinate-nucleotide adenylyltransferase

Products: NA

Alternate protein names: Deamido-NAD(+) diphosphorylase; Deamido-NAD(+) pyrophosphorylase; Nicotinate mononucleotide adenylyltransferase; NaMN adenylyltransferase

Number of amino acids: Translated: 188; Mature: 188

Protein sequence:

>188_residues
MKLAIFGGTFDPIHAGHLAAAREASTRFALDRVLFIPAAHPPHKAGVTHAPYDDRVRMAELACRDDARFEVSRLEEGTAR
SYSIDTIEKVRAMLAPGDGLYFLIGADAFAEIRTWRRWTDVARAVRFLVVSRPGHTYEIPAEVTVDRIDSLEIPISSSEI
RRTLAAGGIPEGLPPAVLAYARDHHLYN

Sequences:

>Translated_188_residues
MKLAIFGGTFDPIHAGHLAAAREASTRFALDRVLFIPAAHPPHKAGVTHAPYDDRVRMAELACRDDARFEVSRLEEGTAR
SYSIDTIEKVRAMLAPGDGLYFLIGADAFAEIRTWRRWTDVARAVRFLVVSRPGHTYEIPAEVTVDRIDSLEIPISSSEI
RRTLAAGGIPEGLPPAVLAYARDHHLYN
>Mature_188_residues
MKLAIFGGTFDPIHAGHLAAAREASTRFALDRVLFIPAAHPPHKAGVTHAPYDDRVRMAELACRDDARFEVSRLEEGTAR
SYSIDTIEKVRAMLAPGDGLYFLIGADAFAEIRTWRRWTDVARAVRFLVVSRPGHTYEIPAEVTVDRIDSLEIPISSSEI
RRTLAAGGIPEGLPPAVLAYARDHHLYN

Specific function: Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)

COG id: COG1057

COG function: function code H; Nicotinic acid mononucleotide adenylyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the nadD family

Homologues:

Organism=Escherichia coli, GI1786858, Length=208, Percent_Identity=31.25, Blast_Score=83, Evalue=1e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NADD_SOLUE (Q01X27)

Other databases:

- EMBL:   CP000473
- RefSeq:   YP_826073.1
- ProteinModelPortal:   Q01X27
- STRING:   Q01X27
- GeneID:   4426937
- GenomeReviews:   CP000473_GR
- KEGG:   sus:Acid_4829
- NMPDR:   fig|234267.9.peg.4582
- eggNOG:   COG1057
- HOGENOM:   HBG739448
- OMA:   TRELMRT
- PhylomeDB:   Q01X27
- HAMAP:   MF_00244
- InterPro:   IPR004821
- InterPro:   IPR004820
- InterPro:   IPR005248
- InterPro:   IPR014729
- Gene3D:   G3DSA:3.40.50.620
- PANTHER:   PTHR12039
- TIGRFAMs:   TIGR00125
- TIGRFAMs:   TIGR00482

Pfam domain/function: PF01467 CTP_transf_2

EC number: =2.7.7.18

Molecular weight: Translated: 20802; Mature: 20802

Theoretical pI: Translated: 6.97; Mature: 6.97

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLAIFGGTFDPIHAGHLAAAREASTRFALDRVLFIPAAHPPHKAGVTHAPYDDRVRMAE
CEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHEEEEECCCCCCCCCCCCCCCCCCHHHHH
LACRDDARFEVSRLEEGTARSYSIDTIEKVRAMLAPGDGLYFLIGADAFAEIRTWRRWTD
HHHCCCCCEEHHHHCCCCCCCCCHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHH
VARAVRFLVVSRPGHTYEIPAEVTVDRIDSLEIPISSSEIRRTLAAGGIPEGLPPAVLAY
HHHHHHHHEECCCCCEEECCCCEEEECCCCCCCCCCHHHHHHHHHHCCCCCCCCHHHHHH
ARDHHLYN
HHHCCCCC
>Mature Secondary Structure
MKLAIFGGTFDPIHAGHLAAAREASTRFALDRVLFIPAAHPPHKAGVTHAPYDDRVRMAE
CEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHEEEEECCCCCCCCCCCCCCCCCCHHHHH
LACRDDARFEVSRLEEGTARSYSIDTIEKVRAMLAPGDGLYFLIGADAFAEIRTWRRWTD
HHHCCCCCEEHHHHCCCCCCCCCHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHH
VARAVRFLVVSRPGHTYEIPAEVTVDRIDSLEIPISSSEIRRTLAAGGIPEGLPPAVLAY
HHHHHHHHEECCCCCEEECCCCEEEECCCCCCCCCCHHHHHHHHHHCCCCCCCCHHHHHH
ARDHHLYN
HHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA