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The map label for this gene is glcD [H]

Identifier: 116623575

GI number: 116623575

Start: 5677787

End: 5678992

Strand: Reverse

Name: glcD [H]

Synonym: Acid_4485

Alternate gene names: 116623575

Gene position: 5678992-5677787 (Counterclockwise)

Preceding gene: 116623576

Following gene: 116623569

Centisome position: 56.99

GC content: 68.66

Gene sequence:

>1206_bases
GTGACCGGGGGACGGGTGCCGTTCGGCGGCTGGGTGCTCTCGCTCGAGAAGTTCACGCGGCTGGATATCGAGTCCGGCTT
CGCGGTTGTCGGCGCGGGGACGCTGCTGCGCGACCTGCATGCCGCGGCGCAGCGTTCCGGCCAGTTCTATCCGCCCGACC
CCACCGAGACGGGCGCGTCGCTGGGCGGGAACATCGCATGCAATGCGAGCGGCTCGCGCAGCTTCCGTTACGGCGCCACG
CGCGCCTGGGTGCGGCGGCTGCGCGTGGTGCTGGCCGACGGCCGCGTTCTGGACGTGAGCCGCGGCGAGCCGGTGGATTT
CGACCCGGGCTCAGTGCCGCTGCCGGCCGTCACCAAGAATACCGCCGGCTACCTGCTGCGCCCAGGCATGGATTGGGTGG
ACCTGTTCACCGGAAGCGAAGGCACGCTCGGCGTGGTCACTGAGGCGACCGTGGGCCTGCTGCCGCTTCCGAAGGCCGTG
CTTGGCGGCGTGGTCTTCTTCCGGAGCGATGGGGAGGCGATCGACGCGGTGGAGAACTGGCGCGGCGGTTCGACGGCCCG
GATGCTGGAGTATTTCGACCGGCCGTCGCTCGATTTGCTGCGCGCGCGTTTTCCGGAGATCCCGGCGGAGGCGGGCGCGG
CGATTTTGTTCGAGCAGGAGATGGCGAGCGAAGAGGATGCGGAGCTCGACCTGTGGCTGGAACGAATCGAAGGCGCGGCG
GGCGCGCTGGGGGAGGGTTCCTGGTTCGCCACCACGGCGAATGACCGGGAGCGCTTCCGCAAATTCCGCCACAGCCTGCC
GGAGCTGGTGAACGACACCGTGCGGCGCAGTGGGGCGCTGAAGATGAATACGGATTTCGCGGTGCCGCTGGAGCGCAACC
GCGAGATGCTGGCGTATTACCGGCGCCGGCTGGAGGAGGAGTTCCCGGGGAGGTACGTGATCTTCGGCCACATCGGGGAT
GCTCACGTGCATGTCAACCTGTTCAGCGATCCGGCCAATCCGGACGCCGCCGCGGGATTACTCAAGGAGTTCGCCCGGCA
TGCCGCGGAGCTGGGCGGGACTGTGTCCGCCGAGCACGGTGTGGGCAAGCGCAAGGCAGGGCTGCTGGCGCTGCAGTATT
CGCCGGAGCATTTGGAGACGATGCGCGCGGTGAAGCGGAGGCTCGACCCGGCCAATATACTCGGGCGCGGCACGATGTGG
GCATGA

Upstream 100 bases:

>100_bases
GCGCGTCCTGATTCCATCGGACGAAGCTGAGATTTCATCGATTCTGCGCGAGGCATCGGCTGCGGGCACTCCGGTAACGG
TTGCCGGCGCCGGGACCGGC

Downstream 100 bases:

>100_bases
GCTGGGTGGCTAGAGTTGTTTGTCATCGATAAGGTGACTTATCCGGAGTAAGCCGCTGCGCTTGCCCGAAGACCGTTTGG
GCCAAAGTACCAGTCGACGA

Product: FAD linked oxidase domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 401; Mature: 400

Protein sequence:

>401_residues
MTGGRVPFGGWVLSLEKFTRLDIESGFAVVGAGTLLRDLHAAAQRSGQFYPPDPTETGASLGGNIACNASGSRSFRYGAT
RAWVRRLRVVLADGRVLDVSRGEPVDFDPGSVPLPAVTKNTAGYLLRPGMDWVDLFTGSEGTLGVVTEATVGLLPLPKAV
LGGVVFFRSDGEAIDAVENWRGGSTARMLEYFDRPSLDLLRARFPEIPAEAGAAILFEQEMASEEDAELDLWLERIEGAA
GALGEGSWFATTANDRERFRKFRHSLPELVNDTVRRSGALKMNTDFAVPLERNREMLAYYRRRLEEEFPGRYVIFGHIGD
AHVHVNLFSDPANPDAAAGLLKEFARHAAELGGTVSAEHGVGKRKAGLLALQYSPEHLETMRAVKRRLDPANILGRGTMW
A

Sequences:

>Translated_401_residues
MTGGRVPFGGWVLSLEKFTRLDIESGFAVVGAGTLLRDLHAAAQRSGQFYPPDPTETGASLGGNIACNASGSRSFRYGAT
RAWVRRLRVVLADGRVLDVSRGEPVDFDPGSVPLPAVTKNTAGYLLRPGMDWVDLFTGSEGTLGVVTEATVGLLPLPKAV
LGGVVFFRSDGEAIDAVENWRGGSTARMLEYFDRPSLDLLRARFPEIPAEAGAAILFEQEMASEEDAELDLWLERIEGAA
GALGEGSWFATTANDRERFRKFRHSLPELVNDTVRRSGALKMNTDFAVPLERNREMLAYYRRRLEEEFPGRYVIFGHIGD
AHVHVNLFSDPANPDAAAGLLKEFARHAAELGGTVSAEHGVGKRKAGLLALQYSPEHLETMRAVKRRLDPANILGRGTMW
A
>Mature_400_residues
TGGRVPFGGWVLSLEKFTRLDIESGFAVVGAGTLLRDLHAAAQRSGQFYPPDPTETGASLGGNIACNASGSRSFRYGATR
AWVRRLRVVLADGRVLDVSRGEPVDFDPGSVPLPAVTKNTAGYLLRPGMDWVDLFTGSEGTLGVVTEATVGLLPLPKAVL
GGVVFFRSDGEAIDAVENWRGGSTARMLEYFDRPSLDLLRARFPEIPAEAGAAILFEQEMASEEDAELDLWLERIEGAAG
ALGEGSWFATTANDRERFRKFRHSLPELVNDTVRRSGALKMNTDFAVPLERNREMLAYYRRRLEEEFPGRYVIFGHIGDA
HVHVNLFSDPANPDAAAGLLKEFARHAAELGGTVSAEHGVGKRKAGLLALQYSPEHLETMRAVKRRLDPANILGRGTMWA

Specific function: Unknown

COG id: COG0277

COG function: function code C; FAD/FMN-containing dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FAD-binding PCMH-type domain [H]

Homologues:

Organism=Homo sapiens, GI119964728, Length=408, Percent_Identity=31.3725490196078, Blast_Score=139, Evalue=3e-33,
Organism=Homo sapiens, GI37595754, Length=404, Percent_Identity=32.6732673267327, Blast_Score=130, Evalue=3e-30,
Organism=Homo sapiens, GI37595756, Length=395, Percent_Identity=32.6582278481013, Blast_Score=129, Evalue=4e-30,
Organism=Escherichia coli, GI1789351, Length=421, Percent_Identity=28.2660332541568, Blast_Score=100, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI71992381, Length=404, Percent_Identity=29.2079207920792, Blast_Score=125, Evalue=5e-29,
Organism=Caenorhabditis elegans, GI71992392, Length=367, Percent_Identity=29.4277929155313, Blast_Score=119, Evalue=4e-27,
Organism=Caenorhabditis elegans, GI71992373, Length=407, Percent_Identity=28.5012285012285, Blast_Score=118, Evalue=5e-27,
Organism=Caenorhabditis elegans, GI17534361, Length=410, Percent_Identity=26.8292682926829, Blast_Score=115, Evalue=6e-26,
Organism=Saccharomyces cerevisiae, GI6320023, Length=416, Percent_Identity=25.7211538461538, Blast_Score=110, Evalue=5e-25,
Organism=Saccharomyces cerevisiae, GI6320764, Length=425, Percent_Identity=26.5882352941176, Blast_Score=102, Evalue=8e-23,
Organism=Saccharomyces cerevisiae, GI6320027, Length=396, Percent_Identity=25, Blast_Score=102, Evalue=1e-22,
Organism=Drosophila melanogaster, GI18921117, Length=407, Percent_Identity=26.2899262899263, Blast_Score=102, Evalue=6e-22,
Organism=Drosophila melanogaster, GI24639277, Length=407, Percent_Identity=26.2899262899263, Blast_Score=102, Evalue=6e-22,
Organism=Drosophila melanogaster, GI24639275, Length=407, Percent_Identity=26.2899262899263, Blast_Score=102, Evalue=6e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016166
- InterPro:   IPR016167
- InterPro:   IPR016164
- InterPro:   IPR016168
- InterPro:   IPR004113
- InterPro:   IPR004490
- InterPro:   IPR006094
- InterPro:   IPR016171 [H]

Pfam domain/function: PF02913 FAD-oxidase_C; PF01565 FAD_binding_4 [H]

EC number: NA

Molecular weight: Translated: 43738; Mature: 43607

Theoretical pI: Translated: 6.13; Mature: 6.13

Prosite motif: PS00482 DIHYDROOROTASE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTGGRVPFGGWVLSLEKFTRLDIESGFAVVGAGTLLRDLHAAAQRSGQFYPPDPTETGAS
CCCCCCCCCCEEEEHHHHHHCCCCCCEEEEEHHHHHHHHHHHHHHCCCCCCCCCCCCCHH
LGGNIACNASGSRSFRYGATRAWVRRLRVVLADGRVLDVSRGEPVDFDPGSVPLPAVTKN
CCCCEEECCCCCCCCCCCHHHHHHHHHHHHEECCEEEECCCCCCCCCCCCCCCCCCCCCC
TAGYLLRPGMDWVDLFTGSEGTLGVVTEATVGLLPLPKAVLGGVVFFRSDGEAIDAVENW
CCCEEECCCCCCEEEECCCCCCEEEEEHHHHCCCCCCHHHHCCEEEECCCCCHHHHHHHC
RGGSTARMLEYFDRPSLDLLRARFPEIPAEAGAAILFEQEMASEEDAELDLWLERIEGAA
CCCCHHHHHHHHCCCCHHHHHHHCCCCCCCCCCEEEEEHHHCCCCCCHHHHHHHHHCCCC
GALGEGSWFATTANDRERFRKFRHSLPELVNDTVRRSGALKMNTDFAVPLERNREMLAYY
CCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCEECCHHCCHHHHHHH
RRRLEEEFPGRYVIFGHIGDAHVHVNLFSDPANPDAAAGLLKEFARHAAELGGTVSAEHG
HHHHHHHCCCCEEEEEECCCEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCEECCCC
VGKRKAGLLALQYSPEHLETMRAVKRRLDPANILGRGTMWA
CCCCCCCEEEEEECHHHHHHHHHHHHHCCHHHHCCCCCCCC
>Mature Secondary Structure 
TGGRVPFGGWVLSLEKFTRLDIESGFAVVGAGTLLRDLHAAAQRSGQFYPPDPTETGAS
CCCCCCCCCEEEEHHHHHHCCCCCCEEEEEHHHHHHHHHHHHHHCCCCCCCCCCCCCHH
LGGNIACNASGSRSFRYGATRAWVRRLRVVLADGRVLDVSRGEPVDFDPGSVPLPAVTKN
CCCCEEECCCCCCCCCCCHHHHHHHHHHHHEECCEEEECCCCCCCCCCCCCCCCCCCCCC
TAGYLLRPGMDWVDLFTGSEGTLGVVTEATVGLLPLPKAVLGGVVFFRSDGEAIDAVENW
CCCEEECCCCCCEEEECCCCCCEEEEEHHHHCCCCCCHHHHCCEEEECCCCCHHHHHHHC
RGGSTARMLEYFDRPSLDLLRARFPEIPAEAGAAILFEQEMASEEDAELDLWLERIEGAA
CCCCHHHHHHHHCCCCHHHHHHHCCCCCCCCCCEEEEEHHHCCCCCCHHHHHHHHHCCCC
GALGEGSWFATTANDRERFRKFRHSLPELVNDTVRRSGALKMNTDFAVPLERNREMLAYY
CCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCEECCHHCCHHHHHHH
RRRLEEEFPGRYVIFGHIGDAHVHVNLFSDPANPDAAAGLLKEFARHAAELGGTVSAEHG
HHHHHHHCCCCEEEEEECCCEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCEECCCC
VGKRKAGLLALQYSPEHLETMRAVKRRLDPANILGRGTMWA
CCCCCCCEEEEEECHHHHHHHHHHHHHCCHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8969504; 9384377 [H]