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The map label for this gene is iolG [H]

Identifier: 116623380

GI number: 116623380

Start: 5432312

End: 5433913

Strand: Reverse

Name: iolG [H]

Synonym: Acid_4289

Alternate gene names: 116623380

Gene position: 5433913-5432312 (Counterclockwise)

Preceding gene: 116623382

Following gene: 116623378

Centisome position: 54.53

GC content: 66.17

Gene sequence:

>1602_bases
ATGCAACGACGCGATCTCCTCAAATCCGCGGCCGCCGGCCTCACCATCCTCAAAAGCGGAGTCCTCCGCGGCCAGAACGC
CCCGAGCAACAAGCTCAACGTCGCCCTCTTCGGCGTCTGGGGACGCGGCACCGCCCACTACAACGTCCTCCGCGGCGAGA
ACGTCGTCGCCATCTGCGACGTGAACGACCTCCGCACCAAAGAGGCCCTCGCCATCTTCCCCAAAGCCAAAACCTATTGG
GACTGGCGCCGCGTCATGGACCAGAAGGACGTCGAAGCCGTCATCATCTGCACCGCCGACCACCACCACGCCTTCATCGC
CAACTGGGCCCTGAATCGCAACATGCACGTCTACTGCGAAAAGCCCCTCGGCATCTCCATCGACGAGGTCCGCACCGTCC
GCGCCAACTACCTCTCCAAGCGCGCCAAGCTCGCCACCCAGCACGGCACCCAGCGCCACGCCTACCCCAACTTCGAGCGT
GTCCGCGAGCTCATCCTCGATGGCGCCATCGGCGACCTGAAGACCGTCCACGGCTGGGACAGCCGCCGACTCCCGCGTCC
TGGCTACCCCACCGCCGAAGGCATGCCCCCCGCCGAGCTCCACTACGAGCAGTGGATCGGCCCCTCCCCCTACCACCCCT
ACAGCCCGCAATACTTCGGCGGCTCCAACGGCCTCAACTGCCTCTTCTGGAATATGTACCGCGATTTCGGCGTCGGCCAG
ATGGGCGACATGGGCGCCCACACCATGGACCTCCTCTGGAACTCCGTGGACGCCGGCGCCCCCACCGGCATCGAGGCCGA
CCTCGAAGTCAGCGACAAGTACGACCCCAACATCACCCCCGTGAAATTGAAGGCGACCTTCGACCACCCCGCCAATGCCT
GGCGCGGCCCCATCCAGATCGTCTGGTATCAGGGCGGCTTAAAACCCAATCCGCCCAAGGGCTACATCGACGTCTCCCGC
ATCGCCAACGGCGCCATCTTCGAGGGCACAAAGGGCGCGATCCTCGCCGACTTCACCACGCGCGTCATCATCCCCAACAA
CGACGATGGCGACCTGACCTACTACAAGCGCCGCTCCAAAGAGGAGACCCTCCCCCTGATCGGCGGCACCGGCCAGGTCA
CCCAGGCCCCGCCGCAGCGCCCCGCCCGCCCCGCCGCCGGTGCTGGCCCGCAGCGCCCCGGCCTGCCCGCCGGCTTCACC
GCCCAGCCCAGCGCCGAGCCCACCGCCAACGGCTTCCCGGAAGTCCAGTTCCTCGACAACGGACGCCTCCCCGCCGCCCT
CGGCCTCCCCAACCCGAGCATCGCCGGCATCCTCGCCGCCGAACAGGCCGGCCGCCCCGTCACCGGCGACGTCTTCCAAC
AGGAATGGCTCGACGCCTGCAAGGGCAAGTCCAATAACGCCGTCCACGGCACCAGCACCAAGACGCATTGCGACTTCGAT
TACAGCGGGACGATGATTGAGCAAATGCTCCTCGGGCTAATTGCCCACCGCGCAGGCAAAAAGCTCGACTACGACCCGAA
GACCGGCCGCGTCACTAACTTCGCCGAGGCTAACGATTGGCTAAAGAGAACTTACCGGACGGGGTGGACTCTGAACGGGT
GA

Upstream 100 bases:

>100_bases
AGATTTTCTTGGCGTTCTTGGCGTCTTGGCGAGAACGTGTTTTGATCCCTGCCTGCGCCCACCCTTGAACCCCGCGCGTA
TCCATGTTACTGCTGTCTCC

Downstream 100 bases:

>100_bases
CAAAGACTCAAAAAAGACGCGCCGAATTCAGATCGTAGCCCACTCTGGTGTTTGTCGCCACATCGAAAATCTCGATCCTC
TCGAAGCTGAAGGTGACTTT

Product: oxidoreductase domain-containing protein

Products: NA

Alternate protein names: Myo-inositol 2-dehydrogenase; MI 2-dehydrogenase [H]

Number of amino acids: Translated: 533; Mature: 533

Protein sequence:

>533_residues
MQRRDLLKSAAAGLTILKSGVLRGQNAPSNKLNVALFGVWGRGTAHYNVLRGENVVAICDVNDLRTKEALAIFPKAKTYW
DWRRVMDQKDVEAVIICTADHHHAFIANWALNRNMHVYCEKPLGISIDEVRTVRANYLSKRAKLATQHGTQRHAYPNFER
VRELILDGAIGDLKTVHGWDSRRLPRPGYPTAEGMPPAELHYEQWIGPSPYHPYSPQYFGGSNGLNCLFWNMYRDFGVGQ
MGDMGAHTMDLLWNSVDAGAPTGIEADLEVSDKYDPNITPVKLKATFDHPANAWRGPIQIVWYQGGLKPNPPKGYIDVSR
IANGAIFEGTKGAILADFTTRVIIPNNDDGDLTYYKRRSKEETLPLIGGTGQVTQAPPQRPARPAAGAGPQRPGLPAGFT
AQPSAEPTANGFPEVQFLDNGRLPAALGLPNPSIAGILAAEQAGRPVTGDVFQQEWLDACKGKSNNAVHGTSTKTHCDFD
YSGTMIEQMLLGLIAHRAGKKLDYDPKTGRVTNFAEANDWLKRTYRTGWTLNG

Sequences:

>Translated_533_residues
MQRRDLLKSAAAGLTILKSGVLRGQNAPSNKLNVALFGVWGRGTAHYNVLRGENVVAICDVNDLRTKEALAIFPKAKTYW
DWRRVMDQKDVEAVIICTADHHHAFIANWALNRNMHVYCEKPLGISIDEVRTVRANYLSKRAKLATQHGTQRHAYPNFER
VRELILDGAIGDLKTVHGWDSRRLPRPGYPTAEGMPPAELHYEQWIGPSPYHPYSPQYFGGSNGLNCLFWNMYRDFGVGQ
MGDMGAHTMDLLWNSVDAGAPTGIEADLEVSDKYDPNITPVKLKATFDHPANAWRGPIQIVWYQGGLKPNPPKGYIDVSR
IANGAIFEGTKGAILADFTTRVIIPNNDDGDLTYYKRRSKEETLPLIGGTGQVTQAPPQRPARPAAGAGPQRPGLPAGFT
AQPSAEPTANGFPEVQFLDNGRLPAALGLPNPSIAGILAAEQAGRPVTGDVFQQEWLDACKGKSNNAVHGTSTKTHCDFD
YSGTMIEQMLLGLIAHRAGKKLDYDPKTGRVTNFAEANDWLKRTYRTGWTLNG
>Mature_533_residues
MQRRDLLKSAAAGLTILKSGVLRGQNAPSNKLNVALFGVWGRGTAHYNVLRGENVVAICDVNDLRTKEALAIFPKAKTYW
DWRRVMDQKDVEAVIICTADHHHAFIANWALNRNMHVYCEKPLGISIDEVRTVRANYLSKRAKLATQHGTQRHAYPNFER
VRELILDGAIGDLKTVHGWDSRRLPRPGYPTAEGMPPAELHYEQWIGPSPYHPYSPQYFGGSNGLNCLFWNMYRDFGVGQ
MGDMGAHTMDLLWNSVDAGAPTGIEADLEVSDKYDPNITPVKLKATFDHPANAWRGPIQIVWYQGGLKPNPPKGYIDVSR
IANGAIFEGTKGAILADFTTRVIIPNNDDGDLTYYKRRSKEETLPLIGGTGQVTQAPPQRPARPAAGAGPQRPGLPAGFT
AQPSAEPTANGFPEVQFLDNGRLPAALGLPNPSIAGILAAEQAGRPVTGDVFQQEWLDACKGKSNNAVHGTSTKTHCDFD
YSGTMIEQMLLGLIAHRAGKKLDYDPKTGRVTNFAEANDWLKRTYRTGWTLNG

Specific function: Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose) [H]

COG id: COG0673

COG function: function code R; Predicted dehydrogenases and related proteins

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gfo/idh/mocA family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016040
- InterPro:   IPR000683
- InterPro:   IPR004104 [H]

Pfam domain/function: PF01408 GFO_IDH_MocA; PF02894 GFO_IDH_MocA_C [H]

EC number: =1.1.1.18 [H]

Molecular weight: Translated: 58675; Mature: 58675

Theoretical pI: Translated: 8.85; Mature: 8.85

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQRRDLLKSAAAGLTILKSGVLRGQNAPSNKLNVALFGVWGRGTAHYNVLRGENVVAICD
CCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEEEECCCCEEEEEECCCCEEEEEC
VNDLRTKEALAIFPKAKTYWDWRRVMDQKDVEAVIICTADHHHAFIANWALNRNMHVYCE
CCCCCCCCEEEEECCCCHHHHHHHHCCCCCCCEEEEEECCCCEEEEEEEEECCCEEEEEC
KPLGISIDEVRTVRANYLSKRAKLATQHGTQRHAYPNFERVRELILDGAIGDLKTVHGWD
CCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCCCCCCEECCCC
SRRLPRPGYPTAEGMPPAELHYEQWIGPSPYHPYSPQYFGGSNGLNCLFWNMYRDFGVGQ
CCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCEEEEEEHHHHCCCCC
MGDMGAHTMDLLWNSVDAGAPTGIEADLEVSDKYDPNITPVKLKATFDHPANAWRGPIQI
CCCCCCHHHHHHHHCCCCCCCCCCCCCEEECCCCCCCCCEEEEEEECCCCCCCCCCCEEE
VWYQGGLKPNPPKGYIDVSRIANGAIFEGTKGAILADFTTRVIIPNNDDGDLTYYKRRSK
EEEECCCCCCCCCCCEEHHHHCCCCEEECCCCCEEEECEEEEEEECCCCCCEEEEECCCC
EETLPLIGGTGQVTQAPPQRPARPAAGAGPQRPGLPAGFTAQPSAEPTANGFPEVQFLDN
CCCCCEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEECC
GRLPAALGLPNPSIAGILAAEQAGRPVTGDVFQQEWLDACKGKSNNAVHGTSTKTHCDFD
CCCCEEECCCCCCCEEEEEHHHCCCCCCHHHHHHHHHHHHCCCCCCCEECCCCCEEECCC
YSGTMIEQMLLGLIAHRAGKKLDYDPKTGRVTNFAEANDWLKRTYRTGWTLNG
CCHHHHHHHHHHHHHHHCCCCCCCCCCCCCEECHHHHHHHHHHHHHCCCEECC
>Mature Secondary Structure
MQRRDLLKSAAAGLTILKSGVLRGQNAPSNKLNVALFGVWGRGTAHYNVLRGENVVAICD
CCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEEEECCCCEEEEEECCCCEEEEEC
VNDLRTKEALAIFPKAKTYWDWRRVMDQKDVEAVIICTADHHHAFIANWALNRNMHVYCE
CCCCCCCCEEEEECCCCHHHHHHHHCCCCCCCEEEEEECCCCEEEEEEEEECCCEEEEEC
KPLGISIDEVRTVRANYLSKRAKLATQHGTQRHAYPNFERVRELILDGAIGDLKTVHGWD
CCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHCCCCCCCCEECCCC
SRRLPRPGYPTAEGMPPAELHYEQWIGPSPYHPYSPQYFGGSNGLNCLFWNMYRDFGVGQ
CCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCEEEEEEHHHHCCCCC
MGDMGAHTMDLLWNSVDAGAPTGIEADLEVSDKYDPNITPVKLKATFDHPANAWRGPIQI
CCCCCCHHHHHHHHCCCCCCCCCCCCCEEECCCCCCCCCEEEEEEECCCCCCCCCCCEEE
VWYQGGLKPNPPKGYIDVSRIANGAIFEGTKGAILADFTTRVIIPNNDDGDLTYYKRRSK
EEEECCCCCCCCCCCEEHHHHCCCCEEECCCCCEEEECEEEEEEECCCCCCEEEEECCCC
EETLPLIGGTGQVTQAPPQRPARPAAGAGPQRPGLPAGFTAQPSAEPTANGFPEVQFLDN
CCCCCEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEECC
GRLPAALGLPNPSIAGILAAEQAGRPVTGDVFQQEWLDACKGKSNNAVHGTSTKTHCDFD
CCCCEEECCCCCCCEEEEEHHHCCCCCCHHHHHHHHHHHHCCCCCCCEECCCCCEEECCC
YSGTMIEQMLLGLIAHRAGKKLDYDPKTGRVTNFAEANDWLKRTYRTGWTLNG
CCHHHHHHHHHHHHHHHCCCCCCCCCCCCCEECHHHHHHHHHHHHHCCCEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA