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The map label for this gene is pat [H]

Identifier: 116623050

GI number: 116623050

Start: 5007548

End: 5008714

Strand: Reverse

Name: pat [H]

Synonym: Acid_3954

Alternate gene names: 116623050

Gene position: 5008714-5007548 (Counterclockwise)

Preceding gene: 116623053

Following gene: 116623046

Centisome position: 50.26

GC content: 63.32

Gene sequence:

>1167_bases
ATGTCCCTTGCCAACCTCACCGATTCGCTTCTGCAGCGCGGATTTACGCGCCGCGATCTGGGCCGCATTACGAGCCTCAT
CACCGCCGGCGCGGCACTGCCGTTCTACAACGAGTACGCGATGGCGCAAGACGCGCAACAGCGCATGATGCGCGGCGCGG
GCGGGGCGCGCAGGGCGATGGATCCCGATGCCGTCCGCATCTCGAGCAACGAAAATCCGCTGGGCCCATGCAAGGAAGGG
CTGGAGGCGATGGCCAAGATCGCGCCGTATGGCGGGCGCTACTCGCCGTTCGGCGAGCAGGGAGAGTTCGTCACCACGGT
CGCGGAGATGGAAGGTATCAAGGAGCCGTACGTCGCTCCGTTCGCGGGTTCGAGCGATCCGCTGCACCGCATCAGCTGCG
CCTTCACGTCGCCGAAGCGGAGTTGGGTGATGGCGAACCCGGGCTACGGCGGTGGCGCGCCGGAATTCATCGGCTCCAAG
ACCACGCGGGTGCCGCTGCGCGCGGATCACAGCCACGATGTGGAAGCTATGATCAAGGCCGACCCCGATGGCGGCGTTTT
TTACGTGTGCAATCCGAATAATCCCTCGGGCACGATCACGGCGCGCAAGGACATCGAGTACCTGCTGGCGAACAAGAAGA
AAGACGCCGTGGTGGTGATCGACGAGGCGTACATTCACTTCTCCGAGAAGGCCCAGCCGTGCAACGATCTGGTGGCCGCC
GATAAAGACGTAATCGTACTGCGAACGTTTTCGAAGGTCTACGGCATGGCCGGCATCCGCGCGGGCTTTGCGATGGGACG
CCCCGACCTGCTCGCGAAGCTGCGGCCTTTCGGCGTCGGGTTCCTGCCGATCACAGGTTTGGCCTGCGCGACCGCGAGCC
TCAAGGCGAAGGGCCTGGTGGCCGAGCGCCGCGGTATCAACAAGAGGATCCGTGAGAATACTTTTGCATTCCTGGAAAAG
AAGGGGATTCCGTTCATCCCCAGCGAGACCAACTTCTTCATGATGGAGGTTAAGCGACCGGGCACGGAATTCGCGCAGGC
GCTGGCCGCGGAGAAGGTCATCATCGGACGCGTGTGGCCGGCATGGCCGACCAAAGTGCGCGTCACGGTGGGCACGCAGG
CGGAGATGGATAAGTTCACCGCCGCGGTATCAAAGGTGGTCGGCTAA

Upstream 100 bases:

>100_bases
TGCGGGGCCTTGACATCCACCGTTTCGGGGGGTATTGTCTGAGGAACCCGTCAGGCCGCTCCGAGTCGAGCAACATTTCG
ATTCAAATAAGGAGCTTCCG

Downstream 100 bases:

>100_bases
CTCAGAAGATCTTTGACCACGTTGCCGTGGACGTCGGTCAGCCGGAAGTGGCGGCCCTGGAATTTATAGGTCAACTTCAG
GTGATCGACGCCCAGGCAGC

Product: aminotransferase

Products: 3-(imidazol-4-yl)-2-oxopropyl phosphate; L-glutamate

Alternate protein names: NA

Number of amino acids: Translated: 388; Mature: 387

Protein sequence:

>388_residues
MSLANLTDSLLQRGFTRRDLGRITSLITAGAALPFYNEYAMAQDAQQRMMRGAGGARRAMDPDAVRISSNENPLGPCKEG
LEAMAKIAPYGGRYSPFGEQGEFVTTVAEMEGIKEPYVAPFAGSSDPLHRISCAFTSPKRSWVMANPGYGGGAPEFIGSK
TTRVPLRADHSHDVEAMIKADPDGGVFYVCNPNNPSGTITARKDIEYLLANKKKDAVVVIDEAYIHFSEKAQPCNDLVAA
DKDVIVLRTFSKVYGMAGIRAGFAMGRPDLLAKLRPFGVGFLPITGLACATASLKAKGLVAERRGINKRIRENTFAFLEK
KGIPFIPSETNFFMMEVKRPGTEFAQALAAEKVIIGRVWPAWPTKVRVTVGTQAEMDKFTAAVSKVVG

Sequences:

>Translated_388_residues
MSLANLTDSLLQRGFTRRDLGRITSLITAGAALPFYNEYAMAQDAQQRMMRGAGGARRAMDPDAVRISSNENPLGPCKEG
LEAMAKIAPYGGRYSPFGEQGEFVTTVAEMEGIKEPYVAPFAGSSDPLHRISCAFTSPKRSWVMANPGYGGGAPEFIGSK
TTRVPLRADHSHDVEAMIKADPDGGVFYVCNPNNPSGTITARKDIEYLLANKKKDAVVVIDEAYIHFSEKAQPCNDLVAA
DKDVIVLRTFSKVYGMAGIRAGFAMGRPDLLAKLRPFGVGFLPITGLACATASLKAKGLVAERRGINKRIRENTFAFLEK
KGIPFIPSETNFFMMEVKRPGTEFAQALAAEKVIIGRVWPAWPTKVRVTVGTQAEMDKFTAAVSKVVG
>Mature_387_residues
SLANLTDSLLQRGFTRRDLGRITSLITAGAALPFYNEYAMAQDAQQRMMRGAGGARRAMDPDAVRISSNENPLGPCKEGL
EAMAKIAPYGGRYSPFGEQGEFVTTVAEMEGIKEPYVAPFAGSSDPLHRISCAFTSPKRSWVMANPGYGGGAPEFIGSKT
TRVPLRADHSHDVEAMIKADPDGGVFYVCNPNNPSGTITARKDIEYLLANKKKDAVVVIDEAYIHFSEKAQPCNDLVAAD
KDVIVLRTFSKVYGMAGIRAGFAMGRPDLLAKLRPFGVGFLPITGLACATASLKAKGLVAERRGINKRIRENTFAFLEKK
GIPFIPSETNFFMMEVKRPGTEFAQALAAEKVIIGRVWPAWPTKVRVTVGTQAEMDKFTAAVSKVVG

Specific function: May catalyze the transamination reaction in phenylalanine biosynthesis [H]

COG id: COG0079

COG function: function code E; Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Escherichia coli, GI1788332, Length=305, Percent_Identity=27.2131147540984, Blast_Score=99, Evalue=4e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001176
- InterPro:   IPR001917
- InterPro:   IPR004839
- InterPro:   IPR005861
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: 2.6.1.9

Molecular weight: Translated: 42051; Mature: 41920

Theoretical pI: Translated: 9.67; Mature: 9.67

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLANLTDSLLQRGFTRRDLGRITSLITAGAALPFYNEYAMAQDAQQRMMRGAGGARRAM
CCHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCC
DPDAVRISSNENPLGPCKEGLEAMAKIAPYGGRYSPFGEQGEFVTTVAEMEGIKEPYVAP
CCCCEEECCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEHHHHHHCCCCCCCCC
FAGSSDPLHRISCAFTSPKRSWVMANPGYGGGAPEFIGSKTTRVPLRADHSHDVEAMIKA
CCCCCCCCCEEEEEEECCCCCEEEECCCCCCCCCHHCCCCCEECEEECCCCCCCEEEEEE
DPDGGVFYVCNPNNPSGTITARKDIEYLLANKKKDAVVVIDEAYIHFSEKAQPCNDLVAA
CCCCCEEEEECCCCCCCEEEEHHHHHHHHCCCCCCEEEEEEEEEEEECCCCCCHHHHHHC
DKDVIVLRTFSKVYGMAGIRAGFAMGRPDLLAKLRPFGVGFLPITGLACATASLKAKGLV
CCCEEEEEEHHHHHCCHHHHHHHCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCHH
AERRGINKRIRENTFAFLEKKGIPFIPSETNFFMMEVKRPGTEFAQALAAEKVIIGRVWP
HHHHCHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHEEEECCCC
AWPTKVRVTVGTQAEMDKFTAAVSKVVG
CCCCEEEEEECCCHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SLANLTDSLLQRGFTRRDLGRITSLITAGAALPFYNEYAMAQDAQQRMMRGAGGARRAM
CHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCC
DPDAVRISSNENPLGPCKEGLEAMAKIAPYGGRYSPFGEQGEFVTTVAEMEGIKEPYVAP
CCCCEEECCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEHHHHHHCCCCCCCCC
FAGSSDPLHRISCAFTSPKRSWVMANPGYGGGAPEFIGSKTTRVPLRADHSHDVEAMIKA
CCCCCCCCCEEEEEEECCCCCEEEECCCCCCCCCHHCCCCCEECEEECCCCCCCEEEEEE
DPDGGVFYVCNPNNPSGTITARKDIEYLLANKKKDAVVVIDEAYIHFSEKAQPCNDLVAA
CCCCCEEEEECCCCCCCEEEEHHHHHHHHCCCCCCEEEEEEEEEEEECCCCCCHHHHHHC
DKDVIVLRTFSKVYGMAGIRAGFAMGRPDLLAKLRPFGVGFLPITGLACATASLKAKGLV
CCCEEEEEEHHHHHCCHHHHHHHCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCHH
AERRGINKRIRENTFAFLEKKGIPFIPSETNFFMMEVKRPGTEFAQALAAEKVIIGRVWP
HHHHCHHHHHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHEEEECCCC
AWPTKVRVTVGTQAEMDKFTAAVSKVVG
CCCCEEEEEECCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: Pyridoxal Phosphate. [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: L-histidinol phosphate; 2-oxoglutarate

Specific reaction: L-histidinol phosphate + 2-oxoglutarate = 3-(imidazol-4-yl)-2-oxopropyl phosphate + L-glutamate

General reaction: Amino group transfer [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA