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The map label for this gene is macB [H]

Identifier: 116622906

GI number: 116622906

Start: 4831177

End: 4832418

Strand: Direct

Name: macB [H]

Synonym: Acid_3807

Alternate gene names: 116622906

Gene position: 4831177-4832418 (Clockwise)

Preceding gene: 116622905

Following gene: 116622909

Centisome position: 48.48

GC content: 61.43

Gene sequence:

>1242_bases
ATGACCAGGCTCGCTTTCGTGAACGGTCTGATGCTCGCCTTCGAGACCATCCGCTCGCACAAACTCCGCGCCTTCCTCAC
CGTGCTCGGCGTCATCATCGGCACCGGCACCATCATCGGCGTCAGCGCCATCCTCGCCGGTTTCGACGCCAATATGACCG
GCGTGCTGCGCAGCTTCGGTCCCAACTCGATCATCGTCTTCAAATTCCCCGTGGGCTTTCGCGTCGGCAACCTCAGCCCC
GAGGAACGCACCCGCAAAAATCTCACCTACGAAAATGCCGTCCACCTGCGCGAGCGTTGCAAGGCCGTAGACGACGTCTC
CGCCATGTTGTTTCCGCCAAACGGCATTCTCAACGTGAAGTACATGGGCAACGAGATGTACGACGTCAATCTCTTCGGCG
TCGAAGAAGGCTACTCGCGCGGCAGCGGCCAGGTCGATATTCACCTCGGCCGTTTCTTCACCGATGAAGAGAGCCACCGC
CGCTCCAACGTTGCAGTAATCGGCGCCGACGTGGAGAAGGGCCTGTTCTCCAACCTCGACCCCATCGGCAAGACCATCCT
GGTGGCCGGCCATGAGTTCACCGTGATCGGCACCATGCTGCGCCCCGCCGCCTCGTTCTTCGGCGACACCGATTCGCGCA
TCCTGCTGCCCTACGGCGCCATGCAGAAGATGTACCCCAACGCCCGCGAAAATGCCATCGTGGTCACGGCTAGCAACGGC
ATGCTCCCGCAGGCGCTCGACGAAGTGCGCACCATCCTTCGCATCGATCGGCGCGTGCCCTATGACAAGCCCGATAACTT
CGCGCTCTCCACCGCCGAGCAGATGGTCTCCGATTTCCACCAGATCACCGCCATGACCTTCCTCGTGATGGCCGTCCTCA
GCTCCATCGGACTCCTGGTCGGCGGCATCGGCGTGATGAACATCATGCTGGTGTCCGTCACCGAGCGCACTTTTGAAATC
GGCATCCGCAAAGCTATCGGCGCCAAGAAGGCCGATATCCTGATTCAATTCCTGATCGAAGCCGCCGCCTTAACCGGCCT
CGGCGGCATCATAGGCATCATCTTCGGCTGGCTGATCTCCCTGATCTCACGCCTCGTCTTCCCTTCCCTGCCGGCCTCCG
TCCCCTTGTGGGCTGCCGTCACCGGCATTGTCATGTCCGTCGGCGTCGGACTTTTCTTCGGCATCTGGCCGGCCAACAAA
GCCGCCCGCCTCGACCCCGTAGTCGCCCTCCGTTACGAGTAA

Upstream 100 bases:

>100_bases
GCGTCGGACTCTCGGCGACCGTCGGCCTCTTCTTCGGAATCTACCCCGCGCGCCGCGCCTCGAAGCTCGATCCCATTGAA
GCCCTGCGGGTGGAGCGCTA

Downstream 100 bases:

>100_bases
GACAAGGCGCTCCGCCTTGTATTACACCGCCCTTGTTTGCTCGCAGGCCGCAGACATCCGCACCGGAATATTCGCCGCCC
CATCAGAGCCGCGACCGTAA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 413; Mature: 412

Protein sequence:

>413_residues
MTRLAFVNGLMLAFETIRSHKLRAFLTVLGVIIGTGTIIGVSAILAGFDANMTGVLRSFGPNSIIVFKFPVGFRVGNLSP
EERTRKNLTYENAVHLRERCKAVDDVSAMLFPPNGILNVKYMGNEMYDVNLFGVEEGYSRGSGQVDIHLGRFFTDEESHR
RSNVAVIGADVEKGLFSNLDPIGKTILVAGHEFTVIGTMLRPAASFFGDTDSRILLPYGAMQKMYPNARENAIVVTASNG
MLPQALDEVRTILRIDRRVPYDKPDNFALSTAEQMVSDFHQITAMTFLVMAVLSSIGLLVGGIGVMNIMLVSVTERTFEI
GIRKAIGAKKADILIQFLIEAAALTGLGGIIGIIFGWLISLISRLVFPSLPASVPLWAAVTGIVMSVGVGLFFGIWPANK
AARLDPVVALRYE

Sequences:

>Translated_413_residues
MTRLAFVNGLMLAFETIRSHKLRAFLTVLGVIIGTGTIIGVSAILAGFDANMTGVLRSFGPNSIIVFKFPVGFRVGNLSP
EERTRKNLTYENAVHLRERCKAVDDVSAMLFPPNGILNVKYMGNEMYDVNLFGVEEGYSRGSGQVDIHLGRFFTDEESHR
RSNVAVIGADVEKGLFSNLDPIGKTILVAGHEFTVIGTMLRPAASFFGDTDSRILLPYGAMQKMYPNARENAIVVTASNG
MLPQALDEVRTILRIDRRVPYDKPDNFALSTAEQMVSDFHQITAMTFLVMAVLSSIGLLVGGIGVMNIMLVSVTERTFEI
GIRKAIGAKKADILIQFLIEAAALTGLGGIIGIIFGWLISLISRLVFPSLPASVPLWAAVTGIVMSVGVGLFFGIWPANK
AARLDPVVALRYE
>Mature_412_residues
TRLAFVNGLMLAFETIRSHKLRAFLTVLGVIIGTGTIIGVSAILAGFDANMTGVLRSFGPNSIIVFKFPVGFRVGNLSPE
ERTRKNLTYENAVHLRERCKAVDDVSAMLFPPNGILNVKYMGNEMYDVNLFGVEEGYSRGSGQVDIHLGRFFTDEESHRR
SNVAVIGADVEKGLFSNLDPIGKTILVAGHEFTVIGTMLRPAASFFGDTDSRILLPYGAMQKMYPNARENAIVVTASNGM
LPQALDEVRTILRIDRRVPYDKPDNFALSTAEQMVSDFHQITAMTFLVMAVLSSIGLLVGGIGVMNIMLVSVTERTFEIG
IRKAIGAKKADILIQFLIEAAALTGLGGIIGIIFGWLISLISRLVFPSLPASVPLWAAVTGIVMSVGVGLFFGIWPANKA
ARLDPVVALRYE

Specific function: Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the membrane and the ATP-binding domain (NBD) is responsible for energy generation [H]

COG id: COG0577

COG function: function code V; ABC-type antimicrobial peptide transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Escherichia coli, GI1787105, Length=413, Percent_Identity=30.9927360774818, Blast_Score=147, Evalue=9e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR017911
- InterPro:   IPR003593
- InterPro:   IPR003838 [H]

Pfam domain/function: PF00005 ABC_tran; PF02687 FtsX [H]

EC number: NA

Molecular weight: Translated: 44889; Mature: 44758

Theoretical pI: Translated: 8.90; Mature: 8.90

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRLAFVNGLMLAFETIRSHKLRAFLTVLGVIIGTGTIIGVSAILAGFDANMTGVLRSFG
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCHHHHHHHCC
PNSIIVFKFPVGFRVGNLSPEERTRKNLTYENAVHLRERCKAVDDVSAMLFPPNGILNVK
CCEEEEEEECCCEEECCCCHHHHHHHCCCHHHHHHHHHHHHHHHCCCEEEECCCCEEEEE
YMGNEMYDVNLFGVEEGYSRGSGQVDIHLGRFFTDEESHRRSNVAVIGADVEKGLFSNLD
EECCEEEEEEEEECCCCCCCCCCEEEEEECCEECCCHHHCCCCEEEEECCHHHHHHCCCC
PIGKTILVAGHEFTVIGTMLRPAASFFGDTDSRILLPYGAMQKMYPNARENAIVVTASNG
CCCCEEEEECCCCEEHHHHHHHHHHHCCCCCCEEEECCHHHHHHCCCCCCCEEEEEECCC
MLPQALDEVRTILRIDRRVPYDKPDNFALSTAEQMVSDFHQITAMTFLVMAVLSSIGLLV
CCHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GGIGVMNIMLVSVTERTFEIGIRKAIGAKKADILIQFLIEAAALTGLGGIIGIIFGWLIS
HHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LISRLVFPSLPASVPLWAAVTGIVMSVGVGLFFGIWPANKAARLDPVVALRYE
HHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHEEECCCCCCCCCCCEEEEECC
>Mature Secondary Structure 
TRLAFVNGLMLAFETIRSHKLRAFLTVLGVIIGTGTIIGVSAILAGFDANMTGVLRSFG
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCHHHHHHHCC
PNSIIVFKFPVGFRVGNLSPEERTRKNLTYENAVHLRERCKAVDDVSAMLFPPNGILNVK
CCEEEEEEECCCEEECCCCHHHHHHHCCCHHHHHHHHHHHHHHHCCCEEEECCCCEEEEE
YMGNEMYDVNLFGVEEGYSRGSGQVDIHLGRFFTDEESHRRSNVAVIGADVEKGLFSNLD
EECCEEEEEEEEECCCCCCCCCCEEEEEECCEECCCHHHCCCCEEEEECCHHHHHHCCCC
PIGKTILVAGHEFTVIGTMLRPAASFFGDTDSRILLPYGAMQKMYPNARENAIVVTASNG
CCCCEEEEECCCCEEHHHHHHHHHHHCCCCCCEEEECCHHHHHHCCCCCCCEEEEEECCC
MLPQALDEVRTILRIDRRVPYDKPDNFALSTAEQMVSDFHQITAMTFLVMAVLSSIGLLV
CCHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GGIGVMNIMLVSVTERTFEIGIRKAIGAKKADILIQFLIEAAALTGLGGIIGIIFGWLIS
HHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LISRLVFPSLPASVPLWAAVTGIVMSVGVGLFFGIWPANKAARLDPVVALRYE
HHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHEEECCCCCCCCCCCEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA