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The map label for this gene is macB [H]

Identifier: 116622905

GI number: 116622905

Start: 4829918

End: 4831177

Strand: Direct

Name: macB [H]

Synonym: Acid_3806

Alternate gene names: 116622905

Gene position: 4829918-4831177 (Clockwise)

Preceding gene: 116622904

Following gene: 116622906

Centisome position: 48.47

GC content: 60.87

Gene sequence:

>1260_bases
GTGTCGGAGACCGCCAAATTCCGTCTGTCCGCGTCCTTTTGGGAAGCCACCCGGATCGCCGTCAATTCCCTGCACAAAAA
CAAACTCCGCACCTTCCTCACTCTGCTCGGCATCATCCTCGCCACCACCACCCTGATCGCCGTCACCGCCCTCATCCACG
GCATGAACCTCTATATCGCCGAAAAGGTCTCCAATATGGGCTCGGATGGTTTCCGCGTTGTGCGCATGGCCTGGTTCGGC
CCCTGGGATCCCAAGAAATTCATGGAAATGCAGAAGCGCAATCCGCAGATCCGTCCCGACGAGTACGAATTCATCAAGGA
TCGCGCCGTGCTCGTCAAAGACGTCGGCATGATGGCTTCCCGCCAGGCCCGCGTGTCTTACAAGGGCGATTCCACCCTCG
GTGTCGATATCGAAGGCGTCACCGAAAATATCCCGGCTATCAACAACGTCCAGATCGAGTCCGGACGCGGCATCACGTAC
GAAGAGGTTCGCCGCCACGCCCCGGTCGCCTTCATCGGCAACGACATTCGCACGCGCTTCTTCGAAGGCCGCGAGGCCAC
CGGCAAATTCATCGAGATCGAAGGCAGTCCCTACGAAGTGGTCGGCTGCGCCAAAACGCTTGGCAGCGTCTTCGGCCAGT
CGCAGGACAACTTTGTCATGATCCCGATCGAGAGTTACTTCAAAACCTACGGCAGCCGCAACGGCATCCGCATGGTCGCC
AAGGCTAACGGCCAGGAACACCTCGCCGAAGCGCAGGATGAGATCCGCGTCCTGCTCCGCTCCTATCGCCACCTCGGCCC
CGGCCAGGATGATAACTTCAGCATTTTCGCCTCGGAAACCATCGTCAACCTCTGGGAGCGGCTCACTTCCACCATCGCCG
GCATGGCAGTCGGCATCGTCAGCGTCTTCATGGTGGTCGGCGGCATCGTGATTATGAATATCATGCTCGCCGTGGTGACG
GAACGCACTCACGAAATCGGCATTCGCAAATCCCTGGGTGCGCGCCGCCGCGACATCCTCAATCAGTACCTGGTGGAATC
CAGCGTCCTCGCGGGCGCAGGAGGCCTGTGCGGAGTCGCCATCGCCTGGATTGTCGCGATCGTCGTCCGCAGCTTCACCT
CCGTCCCGATGGCGCTCCCCTGGACTAGCGTTGCCATCGGCGTCGGACTCTCGGCGACCGTCGGCCTCTTCTTCGGAATC
TACCCCGCGCGCCGCGCCTCGAAGCTCGATCCCATTGAAGCCCTGCGGGTGGAGCGCTAA

Upstream 100 bases:

>100_bases
GCGCTACGCGTACGACATCGGTCGTAGAGCTTCACTCTCCTATAACCTGCATTTCCCTGGAACAAATCTCCTCTCCCCGC
CGTCTTCTCCATCGAATACC

Downstream 100 bases:

>100_bases
TGACCAGGCTCGCTTTCGTGAACGGTCTGATGCTCGCCTTCGAGACCATCCGCTCGCACAAACTCCGCGCCTTCCTCACC
GTGCTCGGCGTCATCATCGG

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 419; Mature: 418

Protein sequence:

>419_residues
MSETAKFRLSASFWEATRIAVNSLHKNKLRTFLTLLGIILATTTLIAVTALIHGMNLYIAEKVSNMGSDGFRVVRMAWFG
PWDPKKFMEMQKRNPQIRPDEYEFIKDRAVLVKDVGMMASRQARVSYKGDSTLGVDIEGVTENIPAINNVQIESGRGITY
EEVRRHAPVAFIGNDIRTRFFEGREATGKFIEIEGSPYEVVGCAKTLGSVFGQSQDNFVMIPIESYFKTYGSRNGIRMVA
KANGQEHLAEAQDEIRVLLRSYRHLGPGQDDNFSIFASETIVNLWERLTSTIAGMAVGIVSVFMVVGGIVIMNIMLAVVT
ERTHEIGIRKSLGARRRDILNQYLVESSVLAGAGGLCGVAIAWIVAIVVRSFTSVPMALPWTSVAIGVGLSATVGLFFGI
YPARRASKLDPIEALRVER

Sequences:

>Translated_419_residues
MSETAKFRLSASFWEATRIAVNSLHKNKLRTFLTLLGIILATTTLIAVTALIHGMNLYIAEKVSNMGSDGFRVVRMAWFG
PWDPKKFMEMQKRNPQIRPDEYEFIKDRAVLVKDVGMMASRQARVSYKGDSTLGVDIEGVTENIPAINNVQIESGRGITY
EEVRRHAPVAFIGNDIRTRFFEGREATGKFIEIEGSPYEVVGCAKTLGSVFGQSQDNFVMIPIESYFKTYGSRNGIRMVA
KANGQEHLAEAQDEIRVLLRSYRHLGPGQDDNFSIFASETIVNLWERLTSTIAGMAVGIVSVFMVVGGIVIMNIMLAVVT
ERTHEIGIRKSLGARRRDILNQYLVESSVLAGAGGLCGVAIAWIVAIVVRSFTSVPMALPWTSVAIGVGLSATVGLFFGI
YPARRASKLDPIEALRVER
>Mature_418_residues
SETAKFRLSASFWEATRIAVNSLHKNKLRTFLTLLGIILATTTLIAVTALIHGMNLYIAEKVSNMGSDGFRVVRMAWFGP
WDPKKFMEMQKRNPQIRPDEYEFIKDRAVLVKDVGMMASRQARVSYKGDSTLGVDIEGVTENIPAINNVQIESGRGITYE
EVRRHAPVAFIGNDIRTRFFEGREATGKFIEIEGSPYEVVGCAKTLGSVFGQSQDNFVMIPIESYFKTYGSRNGIRMVAK
ANGQEHLAEAQDEIRVLLRSYRHLGPGQDDNFSIFASETIVNLWERLTSTIAGMAVGIVSVFMVVGGIVIMNIMLAVVTE
RTHEIGIRKSLGARRRDILNQYLVESSVLAGAGGLCGVAIAWIVAIVVRSFTSVPMALPWTSVAIGVGLSATVGLFFGIY
PARRASKLDPIEALRVER

Specific function: Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation [H]

COG id: COG0577

COG function: function code V; ABC-type antimicrobial peptide transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Escherichia coli, GI1787105, Length=422, Percent_Identity=27.4881516587678, Blast_Score=134, Evalue=1e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR017911
- InterPro:   IPR003593
- InterPro:   IPR003838 [H]

Pfam domain/function: PF00005 ABC_tran; PF02687 FtsX [H]

EC number: NA

Molecular weight: Translated: 46275; Mature: 46144

Theoretical pI: Translated: 9.72; Mature: 9.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSETAKFRLSASFWEATRIAVNSLHKNKLRTFLTLLGIILATTTLIAVTALIHGMNLYIA
CCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHH
EKVSNMGSDGFRVVRMAWFGPWDPKKFMEMQKRNPQIRPDEYEFIKDRAVLVKDVGMMAS
HHHHCCCCCCCEEEEEECCCCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHC
RQARVSYKGDSTLGVDIEGVTENIPAINNVQIESGRGITYEEVRRHAPVAFIGNDIRTRF
CCCEEEECCCCEEEEEECCCCCCCCCCCCEEEECCCCCCHHHHHHCCCEEEECCHHHHHH
FEGREATGKFIEIEGSPYEVVGCAKTLGSVFGQSQDNFVMIPIESYFKTYGSRNGIRMVA
HCCCCCCCCEEEECCCCCHHHHHHHHHHHHHCCCCCCEEEEEHHHHHHHHCCCCCEEEEE
KANGQEHLAEAQDEIRVLLRSYRHLGPGQDDNFSIFASETIVNLWERLTSTIAGMAVGIV
ECCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHH
SVFMVVGGIVIMNIMLAVVTERTHEIGIRKSLGARRRDILNQYLVESSVLAGAGGLCGVA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHCCCCHHHHH
IAWIVAIVVRSFTSVPMALPWTSVAIGVGLSATVGLFFGIYPARRASKLDPIEALRVER
HHHHHHHHHHHHHCCCCCCCHHHHHHHCCHHHHHHHHHHCCCHHHCCCCCCHHHHHCCC
>Mature Secondary Structure 
SETAKFRLSASFWEATRIAVNSLHKNKLRTFLTLLGIILATTTLIAVTALIHGMNLYIA
CCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHH
EKVSNMGSDGFRVVRMAWFGPWDPKKFMEMQKRNPQIRPDEYEFIKDRAVLVKDVGMMAS
HHHHCCCCCCCEEEEEECCCCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHC
RQARVSYKGDSTLGVDIEGVTENIPAINNVQIESGRGITYEEVRRHAPVAFIGNDIRTRF
CCCEEEECCCCEEEEEECCCCCCCCCCCCEEEECCCCCCHHHHHHCCCEEEECCHHHHHH
FEGREATGKFIEIEGSPYEVVGCAKTLGSVFGQSQDNFVMIPIESYFKTYGSRNGIRMVA
HCCCCCCCCEEEECCCCCHHHHHHHHHHHHHCCCCCCEEEEEHHHHHHHHCCCCCEEEEE
KANGQEHLAEAQDEIRVLLRSYRHLGPGQDDNFSIFASETIVNLWERLTSTIAGMAVGIV
ECCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHH
SVFMVVGGIVIMNIMLAVVTERTHEIGIRKSLGARRRDILNQYLVESSVLAGAGGLCGVA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHCCCCHHHHH
IAWIVAIVVRSFTSVPMALPWTSVAIGVGLSATVGLFFGIYPARRASKLDPIEALRVER
HHHHHHHHHHHHHCCCCCCCHHHHHHHCCHHHHHHHHHHCCCHHHCCCCCCHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA