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The map label for this gene is rfbB [C]

Identifier: 116621366

GI number: 116621366

Start: 2871439

End: 2872497

Strand: Reverse

Name: rfbB [C]

Synonym: Acid_2247

Alternate gene names: 116621366

Gene position: 2872497-2871439 (Counterclockwise)

Preceding gene: 116621367

Following gene: 116621365

Centisome position: 28.82

GC content: 68.37

Gene sequence:

>1059_bases
ATGCGGAACTCTCTGGAGCGCGATCTGGACCATGTGCTCTCCCACACCGAAGAGCTGTGGGCCGAGGTGCGCGGCGAGCG
GATCTTCATGACCGGCGGCACCGGTTTCGTCGGCACATGGTTGACGGAGAGCCTGCTCTGGGCCAACCGCCGCTTGTCCC
TCGGGGTGCACGCCGTGCTCCTGACTCGCGATCCCGATGCGTTTCGGCGCCGCTCCCCTCACCTCGCAGAGGATCCAGCC
GTAACTCTGTTAGCCGGCGACGGCCCCACCTTCCCCTACCCCGATGGTGATTTCCCCCTGGTGGTGCACGCGGCCACGGA
GCGGCACGCTCCACCCGGCCCAGCGTGCCCCGCATCCACCCTCGACCGCGATCTCGCCGCCACGCGCCGCGTCCTCGAAC
TCGCTCGCACCCACGGCGCGCGCCGCCTGCTGTTCACCAGCTCCGGCGCCGTCTACGGCCGCCAGCCCGCGTCGCTCAGG
CACGTGCCGGAGGATTATCCCGGGGCGCCGCTCTCGACCGACACGGCCTCGGCATACGGACAGGGCAAACGTATTTCGGA
ATACCTCTGCGCGTGTTATTCGCAGGTCTACGGCTTCGACGCTGTCATCGGCCGCCTCTTCGCCTTCGTCGGCCCCCACC
TTCCGCTCGACGCCAACTACGCGGTCGGCAACTTCATCCGCGACGCCTTCGGGGGAGGCCCGGTGAAGATCGCGGGCGAC
GGCACGCCCTACCGCTCCTACCTCTACGCCGCCGACCTCGCCATCTGGCTCTGGACCTTGCTGATCCGCGGACAAAAGGG
TACGGCGTACAACGTCGGCTCGCCGCATGAAGTCTCGATCGCGGACCTCGCCCGCGTCGTAGTCCGCGAAATCGCGCCGC
AGGCCGGAATATGCATCGCCGGACGGCCCGTCACCGGCGCTCCAGCGCTGCGCTACGTCCCTTCCACTGATCGGGCGGCC
GCACTCGGCCTGCACCCCTGGATCCCGCTGGAGGAAGGCATCCGCCGTACCCGAGATTGGTGCCGCGTCCAGTTGCTCGC
TACTCAACTTCCGGGTTGA

Upstream 100 bases:

>100_bases
TCGGCGTCTACCCCGGCATCACCTCCGCCATGATGGATTACATTCTCGAAAGCTTCCACGCCATTCCCCGAGCAGCCACG
TCGGCGGGTTAAAGGGCTCC

Downstream 100 bases:

>100_bases
GATGTGCGACCTTTGACAAGCCGCGTGCGGTTCCTTTCACAATCCTCATTCTTGTACGTTCCCGCCTTGTTTTAACGACC
CTCTGCAAGTACGATAGGAA

Product: NAD-dependent epimerase/dehydratase

Products: NA

Alternate protein names: Galactowaldenase; UDP-galactose 4-epimerase [H]

Number of amino acids: Translated: 352; Mature: 352

Protein sequence:

>352_residues
MRNSLERDLDHVLSHTEELWAEVRGERIFMTGGTGFVGTWLTESLLWANRRLSLGVHAVLLTRDPDAFRRRSPHLAEDPA
VTLLAGDGPTFPYPDGDFPLVVHAATERHAPPGPACPASTLDRDLAATRRVLELARTHGARRLLFTSSGAVYGRQPASLR
HVPEDYPGAPLSTDTASAYGQGKRISEYLCACYSQVYGFDAVIGRLFAFVGPHLPLDANYAVGNFIRDAFGGGPVKIAGD
GTPYRSYLYAADLAIWLWTLLIRGQKGTAYNVGSPHEVSIADLARVVVREIAPQAGICIAGRPVTGAPALRYVPSTDRAA
ALGLHPWIPLEEGIRRTRDWCRVQLLATQLPG

Sequences:

>Translated_352_residues
MRNSLERDLDHVLSHTEELWAEVRGERIFMTGGTGFVGTWLTESLLWANRRLSLGVHAVLLTRDPDAFRRRSPHLAEDPA
VTLLAGDGPTFPYPDGDFPLVVHAATERHAPPGPACPASTLDRDLAATRRVLELARTHGARRLLFTSSGAVYGRQPASLR
HVPEDYPGAPLSTDTASAYGQGKRISEYLCACYSQVYGFDAVIGRLFAFVGPHLPLDANYAVGNFIRDAFGGGPVKIAGD
GTPYRSYLYAADLAIWLWTLLIRGQKGTAYNVGSPHEVSIADLARVVVREIAPQAGICIAGRPVTGAPALRYVPSTDRAA
ALGLHPWIPLEEGIRRTRDWCRVQLLATQLPG
>Mature_352_residues
MRNSLERDLDHVLSHTEELWAEVRGERIFMTGGTGFVGTWLTESLLWANRRLSLGVHAVLLTRDPDAFRRRSPHLAEDPA
VTLLAGDGPTFPYPDGDFPLVVHAATERHAPPGPACPASTLDRDLAATRRVLELARTHGARRLLFTSSGAVYGRQPASLR
HVPEDYPGAPLSTDTASAYGQGKRISEYLCACYSQVYGFDAVIGRLFAFVGPHLPLDANYAVGNFIRDAFGGGPVKIAGD
GTPYRSYLYAADLAIWLWTLLIRGQKGTAYNVGSPHEVSIADLARVVVREIAPQAGICIAGRPVTGAPALRYVPSTDRAA
ALGLHPWIPLEEGIRRTRDWCRVQLLATQLPG

Specific function: DTDP-L-RHAMNOSE BIOSYNTHESIS WITHIN THE O ANTIGEN BIOSYNTHESIS PATHWAY OF LIPOPOLYSACCHARIDE BIOSYNTHESIS. [C]

COG id: COG0451

COG function: function code MG; Nucleoside-diphosphate-sugar epimerases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sugar epimerase family [H]

Homologues:

Organism=Homo sapiens, GI42516563, Length=346, Percent_Identity=27.7456647398844, Blast_Score=116, Evalue=3e-26,
Organism=Homo sapiens, GI7657641, Length=334, Percent_Identity=23.0538922155689, Blast_Score=82, Evalue=7e-16,
Organism=Escherichia coli, GI1788353, Length=350, Percent_Identity=24.2857142857143, Blast_Score=82, Evalue=7e-17,
Organism=Escherichia coli, GI48994969, Length=343, Percent_Identity=25.6559766763848, Blast_Score=78, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17539532, Length=324, Percent_Identity=26.8518518518519, Blast_Score=104, Evalue=7e-23,
Organism=Drosophila melanogaster, GI21356223, Length=325, Percent_Identity=27.3846153846154, Blast_Score=100, Evalue=2e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001509
- InterPro:   IPR016040 [H]

Pfam domain/function: PF01370 Epimerase [H]

EC number: =5.1.3.2 [H]

Molecular weight: Translated: 38293; Mature: 38293

Theoretical pI: Translated: 7.95; Mature: 7.95

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRNSLERDLDHVLSHTEELWAEVRGERIFMTGGTGFVGTWLTESLLWANRRLSLGVHAVL
CCCHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHHCCCEECCEEEEE
LTRDPDAFRRRSPHLAEDPAVTLLAGDGPTFPYPDGDFPLVVHAATERHAPPGPACPAST
EECCCHHHHHCCCCCCCCCCEEEEECCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCHHH
LDRDLAATRRVLELARTHGARRLLFTSSGAVYGRQPASLRHVPEDYPGAPLSTDTASAYG
HHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCHHCCCCCCCCCCCCCCCCHHHHC
QGKRISEYLCACYSQVYGFDAVIGRLFAFVGPHLPLDANYAVGNFIRDAFGGGPVKIAGD
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCCEEECCC
GTPYRSYLYAADLAIWLWTLLIRGQKGTAYNVGSPHEVSIADLARVVVREIAPQAGICIA
CCCHHHHHHHHHHHHHHHHHHHCCCCCCEECCCCCCEECHHHHHHHHHHHHCCCCCEEEE
GRPVTGAPALRYVPSTDRAAALGLHPWIPLEEGIRRTRDWCRVQLLATQLPG
CCCCCCCCCEEECCCCCCHHEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MRNSLERDLDHVLSHTEELWAEVRGERIFMTGGTGFVGTWLTESLLWANRRLSLGVHAVL
CCCHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHHCCCEECCEEEEE
LTRDPDAFRRRSPHLAEDPAVTLLAGDGPTFPYPDGDFPLVVHAATERHAPPGPACPAST
EECCCHHHHHCCCCCCCCCCEEEEECCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCHHH
LDRDLAATRRVLELARTHGARRLLFTSSGAVYGRQPASLRHVPEDYPGAPLSTDTASAYG
HHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCHHCCCCCCCCCCCCCCCCHHHHC
QGKRISEYLCACYSQVYGFDAVIGRLFAFVGPHLPLDANYAVGNFIRDAFGGGPVKIAGD
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCCEEECCC
GTPYRSYLYAADLAIWLWTLLIRGQKGTAYNVGSPHEVSIADLARVVVREIAPQAGICIA
CCCHHHHHHHHHHHHHHHHHHHCCCCCCEECCCCCCEECHHHHHHHHHHHHCCCCCEEEE
GRPVTGAPALRYVPSTDRAAALGLHPWIPLEEGIRRTRDWCRVQLLATQLPG
CCCCCCCCCEEECCCCCCHHEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]