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The map label for this gene is irgA [H]

Identifier: 116620927

GI number: 116620927

Start: 2248008

End: 2249819

Strand: Reverse

Name: irgA [H]

Synonym: Acid_1808

Alternate gene names: 116620927

Gene position: 2249819-2248008 (Counterclockwise)

Preceding gene: 116620929

Following gene: 116620926

Centisome position: 22.58

GC content: 62.14

Gene sequence:

>1812_bases
TTGCGCCTTACAGCATTTCTCATACCCTCAATTTGGGCCTCAGTCCTAGCCGCAGGGATTCCCGGGATCGCCCTCGCACA
GTTGCCGCAGCCGCGTCAGGAGACCGTTGTGGTCACCGGCACGTACGAACCGATGTCGCTCGAGGAGATCGACCGCGCGA
TTCGCGTGCTTCCCGTGCGCAGCCAGCGCCTGGTTCTCAACACGTTGACTGACGTGCTCAAGCTCGACCCGTCGCTCGAT
CTCGCCGAGCGCGCGCCCGGCGGCGTGCAGGCCGACCTCTCGATCCGCGGCGCCGGGTTCGGCCAGACTCTCGTGCTGTT
GAACGGCATGCGCCTCAACGACCCGCAATCCGGCCACCACAATATGGATATCCCGGTGCCGATGGATAGCGTCTCGCGCG
TCGAGGTCATGCGCGGCTCGGGCTCCACGCTATACGGCTCGGACGCGATGGGCGGCGTTATCAACGTGATCACGGAACCA
CCGCCCACCACCGAATTTCACCTGCGCACCGCGCTGGGCAGCGACGGCATCAATCAGCAGAGCAGTTCCCTCAACATCGC
GGGGAAGAAGCTCTCAGAGCAGTTTTCCTTCGCGCGCGATTTCTCCACGGGCTTCCTCCCAGATCGCGATTACCGCAATC
TGCAATTCGCCAGCGTGACCCGGATCGCCACCAGCATCGGTAACGGATCCATCAACCTCGCCTACATGGACCACCCCTTC
GGCGCCGATCAGTTCTACGGGAATTACAATTCCTGGGAAGATACCAAGACCTGGTTCGCGGGCGTGCAGCAGGCGCTTGG
CGAAAAGACCAGCGCCAGCTTTTCCTTCCGCCGCCACAGCGATCTCTTCGTGCTCTACCGTGACCGACCCGACGTCTTCG
CCAACCACCACTCCGACGAAAGCTACCAGTTGGCGCTGCGCCGCCGCGAAGAGATGTCGCCTACGACGACGCTGTACTAC
GGAGTGGAGGGCTTCCACGAATCGGTGATCAGCAACAATTTGGGCGACCACTCACGCAGCCGCGCGGCGGTCTACGCGGC
AGCCGATTTCCGCGCCCTCCATCGCTTCTCCACGACCATTTCCGCGCGCGAAGAGATTTACCGCAACTTCTCCGGCGCGT
TCACGCCGACGGTCGCCGCCGCATACTGGGCATCGCCGCAGGTGAAGTTTCGCGCTTCCGCCAGCCGCGCCTTTCGCGTG
CCGAGCTACACGGACCTCTACTATCACGACCCCGGGAACGTAGGCAGTCCCACGCTGCGGCCAGAGAGCGCGTGGACCTA
TGAGACCGGCGTGGATTGGACCCCGAGCTCCGTCCTCCGCGGCGACATCACGTTCTTCGAACGGCGCGAACACGACGGCA
TCGATTATTACCGCGCATCCCTCACCGACATCTATCGCGCGCTCAACATCCAGAATTTGAATTTCCGGGGCGTGGAAGCC
TCGCTGCGCTGGACGCCCTCGCGGACTCACATGTTCGATCTCCGCTATACCCACCTGCACGGCACACAGGACACGGTCGC
GGCCGGATTCACCAAGTACACCTTCAACTATCCGACGAACTCCGGGGTCTTCGGCTGGCAGGTGACGCCGCGCGGGAATT
TCGTATTTCGCACGCGTGTGGGCGTGATTCAACGCTACGCGCAATCGCTCTATCCGCTCTGGGATATCTATGCCGGGCTC
CCGAATAAGACGATTCGCCCGTTTTTCCAGGTGACCAACGCCGCCAACTCCTCCTACCAGGACATCCCCAACGTGCCGAT
GCCGGGACGCACTATCATTGGAGGGATCGAGATGGTATTTCGAAAGAGGTAA

Upstream 100 bases:

>100_bases
GTCGTCGCGCACTGGGCGAGGCGTCTGGGCCAACACCTGGTTTAAGAAGTCTTCCGCTGCGTCATTCCAGTTCATGGTCG
AAACCATCATAGAATGAAAG

Downstream 100 bases:

>100_bases
ACCGCATATGAAAACTCTCGGACTTCTTCTAGTTCTCGCAGGCGCGGGTTTTGCCGCGCAGGATGACGGCATCCAGTGGC
TCGGCAGTTATCGCGAGGCC

Product: TonB-dependent receptor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 603; Mature: 603

Protein sequence:

>603_residues
MRLTAFLIPSIWASVLAAGIPGIALAQLPQPRQETVVVTGTYEPMSLEEIDRAIRVLPVRSQRLVLNTLTDVLKLDPSLD
LAERAPGGVQADLSIRGAGFGQTLVLLNGMRLNDPQSGHHNMDIPVPMDSVSRVEVMRGSGSTLYGSDAMGGVINVITEP
PPTTEFHLRTALGSDGINQQSSSLNIAGKKLSEQFSFARDFSTGFLPDRDYRNLQFASVTRIATSIGNGSINLAYMDHPF
GADQFYGNYNSWEDTKTWFAGVQQALGEKTSASFSFRRHSDLFVLYRDRPDVFANHHSDESYQLALRRREEMSPTTTLYY
GVEGFHESVISNNLGDHSRSRAAVYAAADFRALHRFSTTISAREEIYRNFSGAFTPTVAAAYWASPQVKFRASASRAFRV
PSYTDLYYHDPGNVGSPTLRPESAWTYETGVDWTPSSVLRGDITFFERREHDGIDYYRASLTDIYRALNIQNLNFRGVEA
SLRWTPSRTHMFDLRYTHLHGTQDTVAAGFTKYTFNYPTNSGVFGWQVTPRGNFVFRTRVGVIQRYAQSLYPLWDIYAGL
PNKTIRPFFQVTNAANSSYQDIPNVPMPGRTIIGGIEMVFRKR

Sequences:

>Translated_603_residues
MRLTAFLIPSIWASVLAAGIPGIALAQLPQPRQETVVVTGTYEPMSLEEIDRAIRVLPVRSQRLVLNTLTDVLKLDPSLD
LAERAPGGVQADLSIRGAGFGQTLVLLNGMRLNDPQSGHHNMDIPVPMDSVSRVEVMRGSGSTLYGSDAMGGVINVITEP
PPTTEFHLRTALGSDGINQQSSSLNIAGKKLSEQFSFARDFSTGFLPDRDYRNLQFASVTRIATSIGNGSINLAYMDHPF
GADQFYGNYNSWEDTKTWFAGVQQALGEKTSASFSFRRHSDLFVLYRDRPDVFANHHSDESYQLALRRREEMSPTTTLYY
GVEGFHESVISNNLGDHSRSRAAVYAAADFRALHRFSTTISAREEIYRNFSGAFTPTVAAAYWASPQVKFRASASRAFRV
PSYTDLYYHDPGNVGSPTLRPESAWTYETGVDWTPSSVLRGDITFFERREHDGIDYYRASLTDIYRALNIQNLNFRGVEA
SLRWTPSRTHMFDLRYTHLHGTQDTVAAGFTKYTFNYPTNSGVFGWQVTPRGNFVFRTRVGVIQRYAQSLYPLWDIYAGL
PNKTIRPFFQVTNAANSSYQDIPNVPMPGRTIIGGIEMVFRKR
>Mature_603_residues
MRLTAFLIPSIWASVLAAGIPGIALAQLPQPRQETVVVTGTYEPMSLEEIDRAIRVLPVRSQRLVLNTLTDVLKLDPSLD
LAERAPGGVQADLSIRGAGFGQTLVLLNGMRLNDPQSGHHNMDIPVPMDSVSRVEVMRGSGSTLYGSDAMGGVINVITEP
PPTTEFHLRTALGSDGINQQSSSLNIAGKKLSEQFSFARDFSTGFLPDRDYRNLQFASVTRIATSIGNGSINLAYMDHPF
GADQFYGNYNSWEDTKTWFAGVQQALGEKTSASFSFRRHSDLFVLYRDRPDVFANHHSDESYQLALRRREEMSPTTTLYY
GVEGFHESVISNNLGDHSRSRAAVYAAADFRALHRFSTTISAREEIYRNFSGAFTPTVAAAYWASPQVKFRASASRAFRV
PSYTDLYYHDPGNVGSPTLRPESAWTYETGVDWTPSSVLRGDITFFERREHDGIDYYRASLTDIYRALNIQNLNFRGVEA
SLRWTPSRTHMFDLRYTHLHGTQDTVAAGFTKYTFNYPTNSGVFGWQVTPRGNFVFRTRVGVIQRYAQSLYPLWDIYAGL
PNKTIRPFFQVTNAANSSYQDIPNVPMPGRTIIGGIEMVFRKR

Specific function: Involved in the initial step of iron uptake by binding ferric vibriobactin, an iron chelatin siderophore that allows V.cholerae to extract iron from the environment [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell outer membrane [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tonB-dependent receptor family [H]

Homologues:

Organism=Escherichia coli, GI1788478, Length=163, Percent_Identity=34.9693251533742, Blast_Score=87, Evalue=4e-18,
Organism=Escherichia coli, GI1790405, Length=166, Percent_Identity=31.9277108433735, Blast_Score=68, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012910
- InterPro:   IPR000531
- InterPro:   IPR010916
- InterPro:   IPR010917 [H]

Pfam domain/function: PF07715 Plug; PF00593 TonB_dep_Rec [H]

EC number: NA

Molecular weight: Translated: 67519; Mature: 67519

Theoretical pI: Translated: 8.82; Mature: 8.82

Prosite motif: PS00430 TONB_DEPENDENT_REC_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLTAFLIPSIWASVLAAGIPGIALAQLPQPRQETVVVTGTYEPMSLEEIDRAIRVLPVR
CCEEEHHHHHHHHHHHHHCCCCCCHHCCCCCCCCEEEEEECCCCCCHHHHHHHHEEECCC
SQRLVLNTLTDVLKLDPSLDLAERAPGGVQADLSIRGAGFGQTLVLLNGMRLNDPQSGHH
CCHHHHHHHHHHHHCCCCCCHHHCCCCCEEEEEEEECCCCCCEEEEEECEECCCCCCCCC
NMDIPVPMDSVSRVEVMRGSGSTLYGSDAMGGVINVITEPPPTTEFHLRTALGSDGINQQ
CCCCCCCCCCCCCEEEEECCCCEEECCCCCCCEEEEECCCCCCCEEEEEEECCCCCCCCC
SSSLNIAGKKLSEQFSFARDFSTGFLPDRDYRNLQFASVTRIATSIGNGSINLAYMDHPF
CCCCEEHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHCCCCEEEEEEEECCC
GADQFYGNYNSWEDTKTWFAGVQQALGEKTSASFSFRRHSDLFVLYRDRPDVFANHHSDE
CCHHHCCCCCCCCHHHHHHHHHHHHHCCCCCCCEEEEECCCEEEEECCCCCHHCCCCCCC
SYQLALRRREEMSPTTTLYYGVEGFHESVISNNLGDHSRSRAAVYAAADFRALHRFSTTI
HHHHHHHHHHHCCCCEEEEECHHHHHHHHHHCCCCCCCCCCEEEEEHHHHHHHHHHHHHH
SAREEIYRNFSGAFTPTVAAAYWASPQVKFRASASRAFRVPSYTDLYYHDPGNVGSPTLR
HHHHHHHHHCCCCCCHHHHHHHCCCCCEEEEECCCCEEECCCCCEEEEECCCCCCCCCCC
PESAWTYETGVDWTPSSVLRGDITFFERREHDGIDYYRASLTDIYRALNIQNLNFRGVEA
CCCCEEECCCCCCCCHHHHCCCCCEEECCCCCCCHHHHHHHHHHHHHHCCCCCCCCCEEE
SLRWTPSRTHMFDLRYTHLHGTQDTVAAGFTKYTFNYPTNSGVFGWQVTPRGNFVFRTRV
EEEECCCCCEEEEEEEEEECCCCHHHHCCEEEEEEECCCCCCEEEEEECCCCCEEEEHHH
GVIQRYAQSLYPLWDIYAGLPNKTIRPFFQVTNAANSSYQDIPNVPMPGRTIIGGIEMVF
HHHHHHHHHHCCHHHHHHCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHE
RKR
ECC
>Mature Secondary Structure
MRLTAFLIPSIWASVLAAGIPGIALAQLPQPRQETVVVTGTYEPMSLEEIDRAIRVLPVR
CCEEEHHHHHHHHHHHHHCCCCCCHHCCCCCCCCEEEEEECCCCCCHHHHHHHHEEECCC
SQRLVLNTLTDVLKLDPSLDLAERAPGGVQADLSIRGAGFGQTLVLLNGMRLNDPQSGHH
CCHHHHHHHHHHHHCCCCCCHHHCCCCCEEEEEEEECCCCCCEEEEEECEECCCCCCCCC
NMDIPVPMDSVSRVEVMRGSGSTLYGSDAMGGVINVITEPPPTTEFHLRTALGSDGINQQ
CCCCCCCCCCCCCEEEEECCCCEEECCCCCCCEEEEECCCCCCCEEEEEEECCCCCCCCC
SSSLNIAGKKLSEQFSFARDFSTGFLPDRDYRNLQFASVTRIATSIGNGSINLAYMDHPF
CCCCEEHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHCCCCEEEEEEEECCC
GADQFYGNYNSWEDTKTWFAGVQQALGEKTSASFSFRRHSDLFVLYRDRPDVFANHHSDE
CCHHHCCCCCCCCHHHHHHHHHHHHHCCCCCCCEEEEECCCEEEEECCCCCHHCCCCCCC
SYQLALRRREEMSPTTTLYYGVEGFHESVISNNLGDHSRSRAAVYAAADFRALHRFSTTI
HHHHHHHHHHHCCCCEEEEECHHHHHHHHHHCCCCCCCCCCEEEEEHHHHHHHHHHHHHH
SAREEIYRNFSGAFTPTVAAAYWASPQVKFRASASRAFRVPSYTDLYYHDPGNVGSPTLR
HHHHHHHHHCCCCCCHHHHHHHCCCCCEEEEECCCCEEECCCCCEEEEECCCCCCCCCCC
PESAWTYETGVDWTPSSVLRGDITFFERREHDGIDYYRASLTDIYRALNIQNLNFRGVEA
CCCCEEECCCCCCCCHHHHCCCCCEEECCCCCCCHHHHHHHHHHHHHHCCCCCCCCCEEE
SLRWTPSRTHMFDLRYTHLHGTQDTVAAGFTKYTFNYPTNSGVFGWQVTPRGNFVFRTRV
EEEECCCCCEEEEEEEEEECCCCHHHHCCEEEEEEECCCCCCEEEEEECCCCCEEEEHHH
GVIQRYAQSLYPLWDIYAGLPNKTIRPFFQVTNAANSSYQDIPNVPMPGRTIIGGIEMVF
HHHHHHHHHHCCHHHHHHCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHE
RKR
ECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1406279; 2174861 [H]