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The map label for this gene is tldD [H]

Identifier: 116620145

GI number: 116620145

Start: 1263506

End: 1264936

Strand: Reverse

Name: tldD [H]

Synonym: Acid_1018

Alternate gene names: 116620145

Gene position: 1264936-1263506 (Counterclockwise)

Preceding gene: 116620146

Following gene: 116620144

Centisome position: 12.69

GC content: 63.38

Gene sequence:

>1431_bases
ATGCAGTTTTCCGATTCCATCTTCGCAACACGCTTCGGGATCACACGGCAGGACCTCGAAAGCTATCTGGGGGAAGCGCT
CTCGCAAGGGGGCGACTACGCGGACCTTTATTTCGAATATCTGCTCACCAGTTCCATCAGCATCGACGAATCCATGGTGA
AGTCTGCCGCACAGGGAGTTTCCATGGGGGTAGGGGTGCGGGTGATTTCGGGCGAGCGCACGGGCTACGCCTATAGCGAC
GACCTGGCGCCGGAGAAGATCCGCAAGGCGGCCAACGTAGCGGCGCACATCGCGTCGGCACCGAGCAAGGTCGAGAAGTT
CGATCTCAACGAAGGGCGCAAGCACAACCTCTATCCGGTGTTGATCGCGCCGACCGAAACCGCGTTCGGCGACCGGGTGG
AACTGGTGAAGCGGGCCGACCGCGCGGCGCGCGCTTACGATCCGCGAATTTTCCAGGTGCAGGCGGTCTACGCCGATAAT
CTTCGCCAGGTGATGGTGGCAACCAGTGATGGCAGGCTTTCGCTGGACCGGCAGCCGCTGGCGCGGTTAAGCGTTTCGGC
GCTGGCGCGGCAGGCCGGCGGACCGCCGCAGCGAGGTCACTCCGGCGGCGGCGGACGCGTGGAACTCGAGTATTTCCTGA
AGGACAAGACGCCCGAGCAGTTCGCGCTGGAGGCCGCCCGCGAATCAATCGTGATGCTGGATAGTGTGGAAGCTCCGGCG
GGCGAGATGACGGTAGTGCTCGGTCCCGGGTGGCCGGGCATCTTGCTGCACGAGGCGGTGGGCCACGGACTCGAGGCCGA
TTTCAATCGCAAGGGAGTCTCGGCCTTCAGCGGGCGCATGGGCCAGAAGGTGGCGAGCGAACTTTGCACGATCGTGGACG
ATGGCACTATCGGAAGCCGTCGCGGATCCCTCAATGTCGACGACGAAGGTCAGCCGACGCAGCGCAATGTGCTGATCGAA
AACGGCGTGCTGCGCAGCTACCTGCAGGACAAGCTGTCGAGCACGCTGTTGAACACGCCATCCACCGGCAGCGGACGGCG
CGAAAGCTACGCGCACATTCCCATGCCGCGTATGACCAACACCTTCATGATGGCCGGGGAGAGCGACCCGGAAGAGATCA
TCCGCTCCGTGCCGAAGGGCCTCTACTGCGTGAATTTCGGCGGCGGGCAGGTGGACATCACGAGTGGCAACTTCGTGTTC
TCGGCATCGGAAAGCTACTTCATCGAGGACGGCAAGCTGACGCGCCCCGTGCGCAACGCCACCCTGATCGGCAACGGTCC
CGAGGCCCTGAAGTACGTCAGCATGGTGGGCAACGATCTGCGGCTGGATGAAGGCATCGGCACCTGCGGCAAGGACGGGC
AGAGCGTGCCGGTGGGCGTCGGGATCCCGACCATCAAGATCGATCGTATGACCGTGGGAGGCACGGCTTGA

Upstream 100 bases:

>100_bases
TGCGGGAGATGGTGGACGAGGATTGCCGCGCGCTGGGGATCGGGTAGAACCGTAAGGGACCGGTCGGGAACTCAGTCTCA
CTCTGCTAGCCTGAAGGTAT

Downstream 100 bases:

>100_bases
ACGGGAATCATCTATTGGAACTCGCGCAAAACATCATCCGGCAGGCGCAAGCCGCGGGCGCGAGCGACGCCGAATGCACG
ATCGCGGAGGGCGAGGAGTT

Product: microcin-processing peptidase 2

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 476; Mature: 476

Protein sequence:

>476_residues
MQFSDSIFATRFGITRQDLESYLGEALSQGGDYADLYFEYLLTSSISIDESMVKSAAQGVSMGVGVRVISGERTGYAYSD
DLAPEKIRKAANVAAHIASAPSKVEKFDLNEGRKHNLYPVLIAPTETAFGDRVELVKRADRAARAYDPRIFQVQAVYADN
LRQVMVATSDGRLSLDRQPLARLSVSALARQAGGPPQRGHSGGGGRVELEYFLKDKTPEQFALEAARESIVMLDSVEAPA
GEMTVVLGPGWPGILLHEAVGHGLEADFNRKGVSAFSGRMGQKVASELCTIVDDGTIGSRRGSLNVDDEGQPTQRNVLIE
NGVLRSYLQDKLSSTLLNTPSTGSGRRESYAHIPMPRMTNTFMMAGESDPEEIIRSVPKGLYCVNFGGGQVDITSGNFVF
SASESYFIEDGKLTRPVRNATLIGNGPEALKYVSMVGNDLRLDEGIGTCGKDGQSVPVGVGIPTIKIDRMTVGGTA

Sequences:

>Translated_476_residues
MQFSDSIFATRFGITRQDLESYLGEALSQGGDYADLYFEYLLTSSISIDESMVKSAAQGVSMGVGVRVISGERTGYAYSD
DLAPEKIRKAANVAAHIASAPSKVEKFDLNEGRKHNLYPVLIAPTETAFGDRVELVKRADRAARAYDPRIFQVQAVYADN
LRQVMVATSDGRLSLDRQPLARLSVSALARQAGGPPQRGHSGGGGRVELEYFLKDKTPEQFALEAARESIVMLDSVEAPA
GEMTVVLGPGWPGILLHEAVGHGLEADFNRKGVSAFSGRMGQKVASELCTIVDDGTIGSRRGSLNVDDEGQPTQRNVLIE
NGVLRSYLQDKLSSTLLNTPSTGSGRRESYAHIPMPRMTNTFMMAGESDPEEIIRSVPKGLYCVNFGGGQVDITSGNFVF
SASESYFIEDGKLTRPVRNATLIGNGPEALKYVSMVGNDLRLDEGIGTCGKDGQSVPVGVGIPTIKIDRMTVGGTA
>Mature_476_residues
MQFSDSIFATRFGITRQDLESYLGEALSQGGDYADLYFEYLLTSSISIDESMVKSAAQGVSMGVGVRVISGERTGYAYSD
DLAPEKIRKAANVAAHIASAPSKVEKFDLNEGRKHNLYPVLIAPTETAFGDRVELVKRADRAARAYDPRIFQVQAVYADN
LRQVMVATSDGRLSLDRQPLARLSVSALARQAGGPPQRGHSGGGGRVELEYFLKDKTPEQFALEAARESIVMLDSVEAPA
GEMTVVLGPGWPGILLHEAVGHGLEADFNRKGVSAFSGRMGQKVASELCTIVDDGTIGSRRGSLNVDDEGQPTQRNVLIE
NGVLRSYLQDKLSSTLLNTPSTGSGRRESYAHIPMPRMTNTFMMAGESDPEEIIRSVPKGLYCVNFGGGQVDITSGNFVF
SASESYFIEDGKLTRPVRNATLIGNGPEALKYVSMVGNDLRLDEGIGTCGKDGQSVPVGVGIPTIKIDRMTVGGTA

Specific function: Suppresses The Inhibitory Activity Of The Carbon Storage Regulator (Csra). [C]

COG id: COG0312

COG function: function code R; Predicted Zn-dependent proteases and their inactivated homologs

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase U62 family [H]

Homologues:

Organism=Escherichia coli, GI1789640, Length=476, Percent_Identity=51.2605042016807, Blast_Score=461, Evalue=1e-131,
Organism=Escherichia coli, GI1790682, Length=409, Percent_Identity=23.4718826405868, Blast_Score=70, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002510 [H]

Pfam domain/function: PF01523 PmbA_TldD [H]

EC number: NA

Molecular weight: Translated: 51159; Mature: 51159

Theoretical pI: Translated: 5.24; Mature: 5.24

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQFSDSIFATRFGITRQDLESYLGEALSQGGDYADLYFEYLLTSSISIDESMVKSAAQGV
CCCCCCHHHHHCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHCC
SMGVGVRVISGERTGYAYSDDLAPEKIRKAANVAAHIASAPSKVEKFDLNEGRKHNLYPV
CCCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHCCCCCCCCCCCCEEE
LIAPTETAFGDRVELVKRADRAARAYDPRIFQVQAVYADNLRQVMVATSDGRLSLDRQPL
EEECCCCCCCHHHHHHHHHHHHHHHCCCEEEEEEEEECCCCEEEEEEECCCCEEECCCHH
ARLSVSALARQAGGPPQRGHSGGGGRVELEYFLKDKTPEQFALEAARESIVMLDSVEAPA
HHHHHHHHHHHCCCCCCCCCCCCCCEEEEEEEECCCCHHHHHHHHHHCCEEEEECCCCCC
GEMTVVLGPGWPGILLHEAVGHGLEADFNRKGVSAFSGRMGQKVASELCTIVDDGTIGSR
CCEEEEECCCCCHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCC
RGSLNVDDEGQPTQRNVLIENGVLRSYLQDKLSSTLLNTPSTGSGRRESYAHIPMPRMTN
CCCCCCCCCCCCCCCCEEEECHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEECCCCCCCC
TFMMAGESDPEEIIRSVPKGLYCVNFGGGQVDITSGNFVFSASESYFIEDGKLTRPVRNA
EEEEECCCCHHHHHHHCCCCEEEEEECCCEEEEECCCEEEECCCCEEEECCCCCCCCCCE
TLIGNGPEALKYVSMVGNDLRLDEGIGTCGKDGQSVPVGVGIPTIKIDRMTVGGTA
EEECCCHHHHHHHHHHCCCEEECCCCCCCCCCCCCCEEECCCCEEEEEEEECCCCC
>Mature Secondary Structure
MQFSDSIFATRFGITRQDLESYLGEALSQGGDYADLYFEYLLTSSISIDESMVKSAAQGV
CCCCCCHHHHHCCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHCC
SMGVGVRVISGERTGYAYSDDLAPEKIRKAANVAAHIASAPSKVEKFDLNEGRKHNLYPV
CCCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHCCCCCCCCCCCCEEE
LIAPTETAFGDRVELVKRADRAARAYDPRIFQVQAVYADNLRQVMVATSDGRLSLDRQPL
EEECCCCCCCHHHHHHHHHHHHHHHCCCEEEEEEEEECCCCEEEEEEECCCCEEECCCHH
ARLSVSALARQAGGPPQRGHSGGGGRVELEYFLKDKTPEQFALEAARESIVMLDSVEAPA
HHHHHHHHHHHCCCCCCCCCCCCCCEEEEEEEECCCCHHHHHHHHHHCCEEEEECCCCCC
GEMTVVLGPGWPGILLHEAVGHGLEADFNRKGVSAFSGRMGQKVASELCTIVDDGTIGSR
CCEEEEECCCCCHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCC
RGSLNVDDEGQPTQRNVLIENGVLRSYLQDKLSSTLLNTPSTGSGRRESYAHIPMPRMTN
CCCCCCCCCCCCCCCCEEEECHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEECCCCCCCC
TFMMAGESDPEEIIRSVPKGLYCVNFGGGQVDITSGNFVFSASESYFIEDGKLTRPVRNA
EEEEECCCCHHHHHHHCCCCEEEEEECCCEEEEECCCEEEECCCCEEEECCCCCCCCCCE
TLIGNGPEALKYVSMVGNDLRLDEGIGTCGKDGQSVPVGVGIPTIKIDRMTVGGTA
EEECCCHHHHHHHHHHCCCEEECCCCCCCCCCCCCCEEECCCCEEEEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12089438 [H]