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The map label for this gene is ydeN [H]

Identifier: 116620007

GI number: 116620007

Start: 1098823

End: 1100154

Strand: Direct

Name: ydeN [H]

Synonym: Acid_0879

Alternate gene names: 116620007

Gene position: 1098823-1100154 (Clockwise)

Preceding gene: 116620006

Following gene: 116620008

Centisome position: 11.03

GC content: 65.24

Gene sequence:

>1332_bases
ATGAATACAACACGCCGCGATTTCATGGCCGCCAGCCTCGCCGCCCCGCTCATCCGGGCCGCCCCCGCCGCCGACCGGCC
CAACGTGCTGGTCGTCGTGCTCGACGATCTGGGCTGTCACGATCTCGGCTACCTCGGCGCGGCCGACCTGAAAACGCCCC
ACATCGACGCCCTTGCCGCCCGCGGCCTTAAATTCCGCAACTGGTATTCGAACGCCCCCGTCTGCGCTCCCGCACGGTCC
GCGATCCTGACCGGCCGCTTCCCTGCGTCGGCCGGCGTACCCGATAATGGTCCCGCCTTGGCGCACGGCATTCCGACCCT
CGCGTCCGTCCTCAAAGGCAGCGGATATCAGACCGGATGCTTCGGCAAGTGGCACTTGGGCAGCACCGATGAGACCGCGC
CCACCGGCCACGGCTTCGATAGTTTCTACGGCTTTCACAGCGGCTGCGTGGACTACTACTCGCACCGCTTCTATTGGGGC
GATAACTATCACGATCTCTGGCACAACCGCACCGAGATCTTCGAAGACGGCCGCTACCTGACCGAACGCATCGCGGACGA
GGCGGCCGGCTTCATCGGCCGCAACCGGCCCTTCCTAGGCTATGTCGCCTTCAACGCGCCCCACTATCCCATGCACGCAC
CCGCGCAGTACAAAGCGCGATTTCCCAACCTCGCGCCTGAGCGGCAGACTTACGCGGCGATGATCGCGGCAGTCGATGAC
GGAATCGGCCAGATCCAGCGCGCCCTGGAGACCACCGGCGCGGCTGAAAACACTCTCATGTTCTTCATCGGCGACAACGG
CGCGACTACCGAGAAACGCGCCGGCCTCAATGGCGATTTCGCTACCGCCGGCGACAACGGCGTTTTCAAAGGTTACAAAT
TCAGCCTCTTCGATGGCGGAATGCACGTGCCGGGCTTCGTCTCCTGGCCCGCCGGCATCCGCAAAGGCGGCTGGACCGAC
GAACTCGCGATGTCGATGGACATACTCCCGACCATCTGCCGCGCCACCGGCGCTCCGCTGCCCCCTCGCGTCGATGGCTC
CGACCTGCTCAACACCATCGCGAGCAACGCGCCCTCGCCGCATAAATCGCTCTACTGGTCGCAAGGCGGGCAACTGGCCA
CGCGCCGGGGCCCCTGGAAACTCGTCGTCAACGGCCGCCTGTACGATCGCCGCGCCGATGGCAATAAACCCCTCACGGGC
GAGGACGCCGTCTGGCTCTCCAATCTGGACGACAATCCCGGCGAGACGCGGAACCTCCGGCGCACCCACGCTAATCTCGT
CGATGAGCTGCTCACCGATCTGCACCGCTGGCACGACGCCCTGCCGAAGTAA

Upstream 100 bases:

>100_bases
CAAGTATTCCCCCAACTAATGGCATACGTGTGCCTTCCCGCAAGAAGCTTTTGGCTATCCTATTCGTTGTCGCCGACTCC
GAGCGCGAAGGGAGTTTCGT

Downstream 100 bases:

>100_bases
CTGTATACTGCGGAAATGAGAAAAATCGCCGTCGTCCTGCTCCTCTCCGCCCTGCCCGCGCTCTGTCAGGAACGCGTAGA
CCTCGGTGTGGTCGATCGAA

Product: sulfatase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 443; Mature: 443

Protein sequence:

>443_residues
MNTTRRDFMAASLAAPLIRAAPAADRPNVLVVVLDDLGCHDLGYLGAADLKTPHIDALAARGLKFRNWYSNAPVCAPARS
AILTGRFPASAGVPDNGPALAHGIPTLASVLKGSGYQTGCFGKWHLGSTDETAPTGHGFDSFYGFHSGCVDYYSHRFYWG
DNYHDLWHNRTEIFEDGRYLTERIADEAAGFIGRNRPFLGYVAFNAPHYPMHAPAQYKARFPNLAPERQTYAAMIAAVDD
GIGQIQRALETTGAAENTLMFFIGDNGATTEKRAGLNGDFATAGDNGVFKGYKFSLFDGGMHVPGFVSWPAGIRKGGWTD
ELAMSMDILPTICRATGAPLPPRVDGSDLLNTIASNAPSPHKSLYWSQGGQLATRRGPWKLVVNGRLYDRRADGNKPLTG
EDAVWLSNLDDNPGETRNLRRTHANLVDELLTDLHRWHDALPK

Sequences:

>Translated_443_residues
MNTTRRDFMAASLAAPLIRAAPAADRPNVLVVVLDDLGCHDLGYLGAADLKTPHIDALAARGLKFRNWYSNAPVCAPARS
AILTGRFPASAGVPDNGPALAHGIPTLASVLKGSGYQTGCFGKWHLGSTDETAPTGHGFDSFYGFHSGCVDYYSHRFYWG
DNYHDLWHNRTEIFEDGRYLTERIADEAAGFIGRNRPFLGYVAFNAPHYPMHAPAQYKARFPNLAPERQTYAAMIAAVDD
GIGQIQRALETTGAAENTLMFFIGDNGATTEKRAGLNGDFATAGDNGVFKGYKFSLFDGGMHVPGFVSWPAGIRKGGWTD
ELAMSMDILPTICRATGAPLPPRVDGSDLLNTIASNAPSPHKSLYWSQGGQLATRRGPWKLVVNGRLYDRRADGNKPLTG
EDAVWLSNLDDNPGETRNLRRTHANLVDELLTDLHRWHDALPK
>Mature_443_residues
MNTTRRDFMAASLAAPLIRAAPAADRPNVLVVVLDDLGCHDLGYLGAADLKTPHIDALAARGLKFRNWYSNAPVCAPARS
AILTGRFPASAGVPDNGPALAHGIPTLASVLKGSGYQTGCFGKWHLGSTDETAPTGHGFDSFYGFHSGCVDYYSHRFYWG
DNYHDLWHNRTEIFEDGRYLTERIADEAAGFIGRNRPFLGYVAFNAPHYPMHAPAQYKARFPNLAPERQTYAAMIAAVDD
GIGQIQRALETTGAAENTLMFFIGDNGATTEKRAGLNGDFATAGDNGVFKGYKFSLFDGGMHVPGFVSWPAGIRKGGWTD
ELAMSMDILPTICRATGAPLPPRVDGSDLLNTIASNAPSPHKSLYWSQGGQLATRRGPWKLVVNGRLYDRRADGNKPLTG
EDAVWLSNLDDNPGETRNLRRTHANLVDELLTDLHRWHDALPK

Specific function: Unknown

COG id: COG3119

COG function: function code P; Arylsulfatase A and related enzymes

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sulfatase family [H]

Homologues:

Organism=Homo sapiens, GI109389362, Length=472, Percent_Identity=28.1779661016949, Blast_Score=174, Evalue=2e-43,
Organism=Homo sapiens, GI38569405, Length=490, Percent_Identity=29.1836734693878, Blast_Score=173, Evalue=3e-43,
Organism=Homo sapiens, GI38569407, Length=375, Percent_Identity=32.5333333333333, Blast_Score=167, Evalue=2e-41,
Organism=Homo sapiens, GI59797060, Length=465, Percent_Identity=30.752688172043, Blast_Score=167, Evalue=2e-41,
Organism=Homo sapiens, GI4503899, Length=376, Percent_Identity=31.3829787234043, Blast_Score=161, Evalue=1e-39,
Organism=Homo sapiens, GI146229331, Length=441, Percent_Identity=30.8390022675737, Blast_Score=152, Evalue=5e-37,
Organism=Homo sapiens, GI146229329, Length=441, Percent_Identity=30.8390022675737, Blast_Score=152, Evalue=5e-37,
Organism=Homo sapiens, GI6005990, Length=441, Percent_Identity=30.8390022675737, Blast_Score=152, Evalue=5e-37,
Organism=Homo sapiens, GI146229324, Length=441, Percent_Identity=30.8390022675737, Blast_Score=152, Evalue=5e-37,
Organism=Homo sapiens, GI45430057, Length=392, Percent_Identity=30.1020408163265, Blast_Score=146, Evalue=5e-35,
Organism=Homo sapiens, GI31742482, Length=168, Percent_Identity=38.0952380952381, Blast_Score=108, Evalue=1e-23,
Organism=Homo sapiens, GI157266309, Length=163, Percent_Identity=39.8773006134969, Blast_Score=103, Evalue=3e-22,
Organism=Homo sapiens, GI146229327, Length=356, Percent_Identity=28.9325842696629, Blast_Score=100, Evalue=4e-21,
Organism=Homo sapiens, GI53831991, Length=191, Percent_Identity=32.9842931937173, Blast_Score=99, Evalue=9e-21,
Organism=Homo sapiens, GI71852586, Length=139, Percent_Identity=40.2877697841727, Blast_Score=92, Evalue=7e-19,
Organism=Homo sapiens, GI71852584, Length=139, Percent_Identity=40.2877697841727, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI58743319, Length=137, Percent_Identity=35.7664233576642, Blast_Score=86, Evalue=9e-17,
Organism=Homo sapiens, GI4506919, Length=375, Percent_Identity=26.6666666666667, Blast_Score=86, Evalue=1e-16,
Organism=Homo sapiens, GI4557659, Length=410, Percent_Identity=23.4146341463415, Blast_Score=79, Evalue=6e-15,
Organism=Homo sapiens, GI5360208, Length=310, Percent_Identity=24.1935483870968, Blast_Score=76, Evalue=6e-14,
Organism=Escherichia coli, GI87081924, Length=403, Percent_Identity=31.2655086848635, Blast_Score=174, Evalue=7e-45,
Organism=Escherichia coli, GI1790233, Length=478, Percent_Identity=27.8242677824268, Blast_Score=137, Evalue=1e-33,
Organism=Escherichia coli, GI1790112, Length=430, Percent_Identity=26.2790697674419, Blast_Score=111, Evalue=1e-25,
Organism=Caenorhabditis elegans, GI115533416, Length=464, Percent_Identity=28.0172413793103, Blast_Score=139, Evalue=3e-33,
Organism=Caenorhabditis elegans, GI115533418, Length=447, Percent_Identity=27.9642058165548, Blast_Score=127, Evalue=1e-29,
Organism=Caenorhabditis elegans, GI17559078, Length=133, Percent_Identity=33.8345864661654, Blast_Score=84, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24666109, Length=364, Percent_Identity=32.4175824175824, Blast_Score=168, Evalue=6e-42,
Organism=Drosophila melanogaster, GI24666175, Length=382, Percent_Identity=29.5811518324607, Blast_Score=166, Evalue=3e-41,
Organism=Drosophila melanogaster, GI281366397, Length=444, Percent_Identity=29.2792792792793, Blast_Score=164, Evalue=1e-40,
Organism=Drosophila melanogaster, GI281366395, Length=444, Percent_Identity=29.2792792792793, Blast_Score=164, Evalue=1e-40,
Organism=Drosophila melanogaster, GI24666163, Length=444, Percent_Identity=29.2792792792793, Blast_Score=164, Evalue=1e-40,
Organism=Drosophila melanogaster, GI281363223, Length=402, Percent_Identity=30.8457711442786, Blast_Score=162, Evalue=3e-40,
Organism=Drosophila melanogaster, GI24653364, Length=407, Percent_Identity=25.0614250614251, Blast_Score=79, Evalue=4e-15,
Organism=Drosophila melanogaster, GI19922168, Length=407, Percent_Identity=24.8157248157248, Blast_Score=79, Evalue=8e-15,
Organism=Drosophila melanogaster, GI21356831, Length=419, Percent_Identity=24.3436754176611, Blast_Score=75, Evalue=9e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017849
- InterPro:   IPR017850
- InterPro:   IPR000917 [H]

Pfam domain/function: PF00884 Sulfatase [H]

EC number: 3.1.6.- [C]

Molecular weight: Translated: 48272; Mature: 48272

Theoretical pI: Translated: 7.10; Mature: 7.10

Prosite motif: PS00523 SULFATASE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNTTRRDFMAASLAAPLIRAAPAADRPNVLVVVLDDLGCHDLGYLGAADLKTPHIDALAA
CCCCHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCHHHHHH
RGLKFRNWYSNAPVCAPARSAILTGRFPASAGVPDNGPALAHGIPTLASVLKGSGYQTGC
CCCEEEHHCCCCCCCCCCCHHEEECCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCC
FGKWHLGSTDETAPTGHGFDSFYGFHSGCVDYYSHRFYWGDNYHDLWHNRTEIFEDGRYL
CEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCEEEECCCHHHHHCCHHHHHHCHHHH
TERIADEAAGFIGRNRPFLGYVAFNAPHYPMHAPAQYKARFPNLAPERQTYAAMIAAVDD
HHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCCHHHHHCCCCCCCCHHHHHHHHHHHHH
GIGQIQRALETTGAAENTLMFFIGDNGATTEKRAGLNGDFATAGDNGVFKGYKFSLFDGG
HHHHHHHHHHHCCCCCCEEEEEECCCCCCHHHHCCCCCCCCCCCCCCCCCCEEEEEECCC
MHVPGFVSWPAGIRKGGWTDELAMSMDILPTICRATGAPLPPRVDGSDLLNTIASNAPSP
CCCCCEEECCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCCC
HKSLYWSQGGQLATRRGPWKLVVNGRLYDRRADGNKPLTGEDAVWLSNLDDNPGETRNLR
CHHEEECCCCCEEECCCCEEEEECCEEEECCCCCCCCCCCCCCEEEECCCCCCCCHHHHH
RTHANLVDELLTDLHRWHDALPK
HHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MNTTRRDFMAASLAAPLIRAAPAADRPNVLVVVLDDLGCHDLGYLGAADLKTPHIDALAA
CCCCHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCHHHHHH
RGLKFRNWYSNAPVCAPARSAILTGRFPASAGVPDNGPALAHGIPTLASVLKGSGYQTGC
CCCEEEHHCCCCCCCCCCCHHEEECCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCC
FGKWHLGSTDETAPTGHGFDSFYGFHSGCVDYYSHRFYWGDNYHDLWHNRTEIFEDGRYL
CEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCEEEECCCHHHHHCCHHHHHHCHHHH
TERIADEAAGFIGRNRPFLGYVAFNAPHYPMHAPAQYKARFPNLAPERQTYAAMIAAVDD
HHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCCHHHHHCCCCCCCCHHHHHHHHHHHHH
GIGQIQRALETTGAAENTLMFFIGDNGATTEKRAGLNGDFATAGDNGVFKGYKFSLFDGG
HHHHHHHHHHHCCCCCCEEEEEECCCCCCHHHHCCCCCCCCCCCCCCCCCCEEEEEECCC
MHVPGFVSWPAGIRKGGWTDELAMSMDILPTICRATGAPLPPRVDGSDLLNTIASNAPSP
CCCCCEEECCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCCC
HKSLYWSQGGQLATRRGPWKLVVNGRLYDRRADGNKPLTGEDAVWLSNLDDNPGETRNLR
CHHEEECCCCCEEECCCCEEEEECCEEEECCCCCCCCCCCCCCEEEECCCCCCCCHHHHH
RTHANLVDELLTDLHRWHDALPK
HHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503 [H]