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The map label for this gene is dmsB [H]

Identifier: 116619325

GI number: 116619325

Start: 232125

End: 233648

Strand: Direct

Name: dmsB [H]

Synonym: Acid_0182

Alternate gene names: 116619325

Gene position: 232125-233648 (Clockwise)

Preceding gene: 116619324

Following gene: 116619326

Centisome position: 2.33

GC content: 65.42

Gene sequence:

>1524_bases
TTGACCGGGTTACCCCTGCTCGAAAGCGACTTGCTCTACCGGCCGGTGCCTACCGGACTCGTGCAGCTCCGCCGTGCGCC
GGAACTGACTCCGCGCCGACCCCTCGCGGCCGGCGAGCAGTACCGGTTTCACTTCGACATGACGAAGTGCATCGGCTGCA
AATGCTGCGTGGTGGCCTGCAACGAACAGAACGGTAATCCCGCCGCCATCAACTGGCGCCGCGTCGGCGAGATCGAGGGC
GGCCACTATCCCTACACCCAGCGTCACTACCTTTCGATGGGCTGCAATCACTGTATCGAGCCCTCCTGCATGACCGGCTG
CCCGGTGGAAGCCTACACCAAAAACGCCATTACGGGCGTGGTCGAGCACAGCGCCGACGCCTGCATCGGCTGCCAGTACT
GCACCTGGAACTGCTCCTACGGCGTGCCGCAATACAACCCGGCGCGCGGGGTCGTCGGCAAATGCGACATGTGCCACAAC
CGCTTGACCGATGGCATGGCGCCCGCGTGCGTCCAAGCCTGTCCGGAGGGCGCAATCGCAATCGAAATCGTCAACGTCGC
GCAATGGCGTGCCGACTACCTGGACGCCAACGCGCCCGGCCTGCCCTCCGCGGACGACAGCATCTCCACTACGCGCATCA
CCCTTCCCGCTAACCTCGCGCCGGACACCGGGCGTGTCGATACCCAGCGCATTCATCCGGAAGATCCGCACCTACCGCTG
GTTTTTATGCTCGTCCTGACGCAGCTTGCCGTCGGCGCATTCGGAGTTCTCTGGCTGCTTGACCTCCTGGGGCACGCCGG
CCGCCTGTGGATCTCCGCGATAGCGTCTTTGACGCTTGCCGGCGTGAGCCTCGGCGCCTCCACGCTCCACCTGGGCCGTC
CCATCTACGCTTGGCGCGCCTTGCGCGGACTCCGCACCTCGTGGTTGAGCCGCGAAGTCCTGGCCCTCTCTCTCTTCGCC
GCCATCGCGTCCTTATTTGCTGGAACGCTGGCTGCGAATCTGCCGGGAAGGACTTGGATCGGGCTCGCGACTGTCGCCTT
CGGCGTCGCCGGCATCACCTGCTCGGCTCGCATCTACCTGGTGCGTGCGCGTCCCTCTTGGTGCAGCCGGTACACCACCG
CCGAATTCTTTGCGACCGCTCTCCTGCTCGGTCCCCTCTTCGTGCTCGCCATGCCCGTATCGAGTGTTCCGTGGATTGCG
TGGATGGCGGCCGTTGGCGGTGCCGCGCAGCTGATCACGCAAGCCGCAAAGTTCCTCTGGCTCTCGCACTCCGAGACCTT
CGAATTGCGGGCCTCCTCCCGCCTGATCTCCGGACGGTTTCGAGCACTGTTTCTGATCCGGCTCGGACTCCTGCTGATTG
CCGGAATCGTAGCGCCCCTTGCCTTGCACGGCAGCGCCGTCGCGGTTGCCGCGTTTGTCCTCGCGCTCGCGGGCGAGTGG
TCGGGACGCTGGCTCTTCTTCGTCACCGTGGTTCCCAAGAACATGGCCGCGGCCTTCCCGGCCACGGCGAGGGTGGCTGC
ATGA

Upstream 100 bases:

>100_bases
GCCGCCAGGTGGAGGTGAAGGCCCCGGCCGTAATGGTGATCGGCGAAGTGGTCCGCCACCGGACCGCGGTGCGTAGAGCC
ATGCTGCAGGAGGCGGTCGC

Downstream 100 bases:

>100_bases
ACTTCAAGCGCATGATCGGCCTCGATAACCTCGCAACCGAATACACATTCGCGCGCGATTCCGAAACCGGGTATACCGCG
GCATCCCGCATCCCCGCGAA

Product: 4Fe-4S ferredoxin iron-sulfur binding domain-containing protein

Products: Reduced form of N-Oxide compounds [C]

Alternate protein names: DMSO reductase iron-sulfur subunit [H]

Number of amino acids: Translated: 507; Mature: 506

Protein sequence:

>507_residues
MTGLPLLESDLLYRPVPTGLVQLRRAPELTPRRPLAAGEQYRFHFDMTKCIGCKCCVVACNEQNGNPAAINWRRVGEIEG
GHYPYTQRHYLSMGCNHCIEPSCMTGCPVEAYTKNAITGVVEHSADACIGCQYCTWNCSYGVPQYNPARGVVGKCDMCHN
RLTDGMAPACVQACPEGAIAIEIVNVAQWRADYLDANAPGLPSADDSISTTRITLPANLAPDTGRVDTQRIHPEDPHLPL
VFMLVLTQLAVGAFGVLWLLDLLGHAGRLWISAIASLTLAGVSLGASTLHLGRPIYAWRALRGLRTSWLSREVLALSLFA
AIASLFAGTLAANLPGRTWIGLATVAFGVAGITCSARIYLVRARPSWCSRYTTAEFFATALLLGPLFVLAMPVSSVPWIA
WMAAVGGAAQLITQAAKFLWLSHSETFELRASSRLISGRFRALFLIRLGLLLIAGIVAPLALHGSAVAVAAFVLALAGEW
SGRWLFFVTVVPKNMAAAFPATARVAA

Sequences:

>Translated_507_residues
MTGLPLLESDLLYRPVPTGLVQLRRAPELTPRRPLAAGEQYRFHFDMTKCIGCKCCVVACNEQNGNPAAINWRRVGEIEG
GHYPYTQRHYLSMGCNHCIEPSCMTGCPVEAYTKNAITGVVEHSADACIGCQYCTWNCSYGVPQYNPARGVVGKCDMCHN
RLTDGMAPACVQACPEGAIAIEIVNVAQWRADYLDANAPGLPSADDSISTTRITLPANLAPDTGRVDTQRIHPEDPHLPL
VFMLVLTQLAVGAFGVLWLLDLLGHAGRLWISAIASLTLAGVSLGASTLHLGRPIYAWRALRGLRTSWLSREVLALSLFA
AIASLFAGTLAANLPGRTWIGLATVAFGVAGITCSARIYLVRARPSWCSRYTTAEFFATALLLGPLFVLAMPVSSVPWIA
WMAAVGGAAQLITQAAKFLWLSHSETFELRASSRLISGRFRALFLIRLGLLLIAGIVAPLALHGSAVAVAAFVLALAGEW
SGRWLFFVTVVPKNMAAAFPATARVAA
>Mature_506_residues
TGLPLLESDLLYRPVPTGLVQLRRAPELTPRRPLAAGEQYRFHFDMTKCIGCKCCVVACNEQNGNPAAINWRRVGEIEGG
HYPYTQRHYLSMGCNHCIEPSCMTGCPVEAYTKNAITGVVEHSADACIGCQYCTWNCSYGVPQYNPARGVVGKCDMCHNR
LTDGMAPACVQACPEGAIAIEIVNVAQWRADYLDANAPGLPSADDSISTTRITLPANLAPDTGRVDTQRIHPEDPHLPLV
FMLVLTQLAVGAFGVLWLLDLLGHAGRLWISAIASLTLAGVSLGASTLHLGRPIYAWRALRGLRTSWLSREVLALSLFAA
IASLFAGTLAANLPGRTWIGLATVAFGVAGITCSARIYLVRARPSWCSRYTTAEFFATALLLGPLFVLAMPVSSVPWIAW
MAAVGGAAQLITQAAKFLWLSHSETFELRASSRLISGRFRALFLIRLGLLLIAGIVAPLALHGSAVAVAAFVLALAGEWS
GRWLFFVTVVPKNMAAAFPATARVAA

Specific function: Electron transfer subunit of the terminal reductase during anaerobic growth on various sulfoxide and N-oxide compounds [H]

COG id: COG0437

COG function: function code C; Fe-S-cluster-containing hydrogenase components 1

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 3 4Fe-4S ferredoxin-type domains [H]

Homologues:

Organism=Escherichia coli, GI1787122, Length=190, Percent_Identity=36.3157894736842, Blast_Score=119, Evalue=7e-28,
Organism=Escherichia coli, GI1787872, Length=204, Percent_Identity=35.7843137254902, Blast_Score=118, Evalue=9e-28,
Organism=Escherichia coli, GI1790326, Length=191, Percent_Identity=32.9842931937173, Blast_Score=100, Evalue=3e-22,
Organism=Escherichia coli, GI1789370, Length=165, Percent_Identity=33.3333333333333, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI2367345, Length=146, Percent_Identity=34.9315068493151, Blast_Score=96, Evalue=4e-21,
Organism=Escherichia coli, GI1787749, Length=175, Percent_Identity=33.7142857142857, Blast_Score=96, Evalue=7e-21,
Organism=Escherichia coli, GI226510944, Length=136, Percent_Identity=36.7647058823529, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI2367245, Length=145, Percent_Identity=33.7931034482759, Blast_Score=71, Evalue=2e-13,
Organism=Escherichia coli, GI87082180, Length=181, Percent_Identity=28.7292817679558, Blast_Score=67, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001450
- InterPro:   IPR017896
- InterPro:   IPR017900
- InterPro:   IPR014297 [H]

Pfam domain/function: PF00037 Fer4 [H]

EC number: NA

Molecular weight: Translated: 54502; Mature: 54371

Theoretical pI: Translated: 8.41; Mature: 8.41

Prosite motif: PS00086 CYTOCHROME_P450

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.7 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
3.8 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTGLPLLESDLLYRPVPTGLVQLRRAPELTPRRPLAAGEQYRFHFDMTKCIGCKCCVVAC
CCCCCCCCCCCCCCCCCHHHHHHHCCCCCCCCCCCCCCCCEEEEECHHHHCCCEEEEEEE
NEQNGNPAAINWRRVGEIEGGHYPYTQRHYLSMGCNHCIEPSCMTGCPVEAYTKNAITGV
ECCCCCCCEEEEEEECCCCCCCCCCCHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHH
VEHSADACIGCQYCTWNCSYGVPQYNPARGVVGKCDMCHNRLTDGMAPACVQACPEGAIA
HHCCCCCEEECEEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHCCCCHHHHHHCCCCCEE
IEIVNVAQWRADYLDANAPGLPSADDSISTTRITLPANLAPDTGRVDTQRIHPEDPHLPL
EEEEHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCHHH
VFMLVLTQLAVGAFGVLWLLDLLGHAGRLWISAIASLTLAGVSLGASTLHLGRPIYAWRA
HHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCHHHHCCCHHHHHHH
LRGLRTSWLSREVLALSLFAAIASLFAGTLAANLPGRTWIGLATVAFGVAGITCSARIYL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCEEEEEEEEE
VRARPSWCSRYTTAEFFATALLLGPLFVLAMPVSSVPWIAWMAAVGGAAQLITQAAKFLW
EECCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCHHHHHHHHHHHHHE
LSHSETFELRASSRLISGRFRALFLIRLGLLLIAGIVAPLALHGSAVAVAAFVLALAGEW
ECCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCC
SGRWLFFVTVVPKNMAAAFPATARVAA
CCCEEEEEEEECCCHHHHCCCHHCCCC
>Mature Secondary Structure 
TGLPLLESDLLYRPVPTGLVQLRRAPELTPRRPLAAGEQYRFHFDMTKCIGCKCCVVAC
CCCCCCCCCCCCCCCCHHHHHHHCCCCCCCCCCCCCCCCEEEEECHHHHCCCEEEEEEE
NEQNGNPAAINWRRVGEIEGGHYPYTQRHYLSMGCNHCIEPSCMTGCPVEAYTKNAITGV
ECCCCCCCEEEEEEECCCCCCCCCCCHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHH
VEHSADACIGCQYCTWNCSYGVPQYNPARGVVGKCDMCHNRLTDGMAPACVQACPEGAIA
HHCCCCCEEECEEEEEECCCCCCCCCCCCCCCCCHHHHHHHHHCCCCHHHHHHCCCCCEE
IEIVNVAQWRADYLDANAPGLPSADDSISTTRITLPANLAPDTGRVDTQRIHPEDPHLPL
EEEEHHHHHHHHHCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCCHHH
VFMLVLTQLAVGAFGVLWLLDLLGHAGRLWISAIASLTLAGVSLGASTLHLGRPIYAWRA
HHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCHHHHCCCHHHHHHH
LRGLRTSWLSREVLALSLFAAIASLFAGTLAANLPGRTWIGLATVAFGVAGITCSARIYL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCEEEEEEEEE
VRARPSWCSRYTTAEFFATALLLGPLFVLAMPVSSVPWIAWMAAVGGAAQLITQAAKFLW
EECCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCHHHHHHHHHHHHHE
LSHSETFELRASSRLISGRFRALFLIRLGLLLIAGIVAPLALHGSAVAVAAFVLALAGEW
ECCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCC
SGRWLFFVTVVPKNMAAAFPATARVAA
CCCEEEEEEEECCCHHHHCCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: Iron-Sulfur Cluster. [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: N-Oxide; Sulfoxide Compounds Including Trimethylamine N-Oxide. [C]

Specific reaction: Reduces Various N-Oxide And Sulfoxide Compounds Including Trimethylamine N-Oxide. [C]

General reaction: Oxidoreductases [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7542800; 8635740 [H]