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The map label for this gene is nudB [C]

Identifier: 116496242

GI number: 116496242

Start: 2802942

End: 2803406

Strand: Direct

Name: nudB [C]

Synonym: LSEI_2820

Alternate gene names: 116496242

Gene position: 2802942-2803406 (Clockwise)

Preceding gene: 116496240

Following gene: 116496243

Centisome position: 96.81

GC content: 48.17

Gene sequence:

>465_bases
GTGGCAGATTATATTAAAGATATCCGGACAAAGGTTGGTCATGCGCCCTTGATTATGGCTGGCGTGATTGGCATCCTGAC
CGATCAGGCTGGGCGCGTTCTACTCCAACAACGCAGCGATTTTACCGGTGAATGGGGCTTGATTAGCGGGACGATCGAAT
ACGGTGAAACCCCTGCCCAGACGATGGTGCGTGAATTCAAAGAAGAAACCAATCTGGAGGTTGAAGTTGTCCGGTTGCTT
GGCGTTAATGGCAATCTCACCCTCACCTATCCAAATGGCGATGTTGCCCAATGGTTGTGCCCGGTGTTTCTTGTGAAACA
ATTAAGCGGTGTGTTAAATAGTGACAACAGTGAGACTGAAGCCTTAAAATTTTGGGATCCAGCAGCCGCTCCTGACCTGT
TTAATCAACAACATCGGGAAGTCTTGGCGCACTTTATCGCAAATGAAACGGGGTATTTTGATTGA

Upstream 100 bases:

>100_bases
CACAATTATTGCCCAGGAAATAATGCAATCGTCAACTATGTTAATGTCAGTATAGCGGTAAACGATTCGAGTTAATCTTA
GATAAGGAGTGAATCTCATA

Downstream 100 bases:

>100_bases
ATCGATTGATCATTCTGCGTGGCAATTCAGGCAGTGGTAAAACCACCACCGCAACCGCCTTGCGTACCCAACTGGCCAAT
ACGCTGCTAGTATCTTAAGA

Product: ADP-ribose pyrophosphatase

Products: dAMP; pyrophosphate [C]

Alternate protein names: NA

Number of amino acids: Translated: 154; Mature: 153

Protein sequence:

>154_residues
MADYIKDIRTKVGHAPLIMAGVIGILTDQAGRVLLQQRSDFTGEWGLISGTIEYGETPAQTMVREFKEETNLEVEVVRLL
GVNGNLTLTYPNGDVAQWLCPVFLVKQLSGVLNSDNSETEALKFWDPAAAPDLFNQQHREVLAHFIANETGYFD

Sequences:

>Translated_154_residues
MADYIKDIRTKVGHAPLIMAGVIGILTDQAGRVLLQQRSDFTGEWGLISGTIEYGETPAQTMVREFKEETNLEVEVVRLL
GVNGNLTLTYPNGDVAQWLCPVFLVKQLSGVLNSDNSETEALKFWDPAAAPDLFNQQHREVLAHFIANETGYFD
>Mature_153_residues
ADYIKDIRTKVGHAPLIMAGVIGILTDQAGRVLLQQRSDFTGEWGLISGTIEYGETPAQTMVREFKEETNLEVEVVRLLG
VNGNLTLTYPNGDVAQWLCPVFLVKQLSGVLNSDNSETEALKFWDPAAAPDLFNQQHREVLAHFIANETGYFD

Specific function: Hydrolysis Of Nucleoside Triphosphates With A Preference For Datp. [C]

COG id: COG0494

COG function: function code LR; NTP pyrophosphohydrolases including oxidative damage repair enzymes

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 nudix hydrolase domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005834
- InterPro:   IPR023214
- InterPro:   IPR006357
- InterPro:   IPR023215
- InterPro:   IPR020476
- InterPro:   IPR020084
- InterPro:   IPR000086
- InterPro:   IPR015797 [H]

Pfam domain/function: PF00702 Hydrolase; PF00293 NUDIX [H]

EC number: 3.6.1.- [C]

Molecular weight: Translated: 17112; Mature: 16980

Theoretical pI: Translated: 4.33; Mature: 4.33

Prosite motif: PS00893 NUDIX

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADYIKDIRTKVGHAPLIMAGVIGILTDQAGRVLLQQRSDFTGEWGLISGTIEYGETPAQ
CHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEECCCCCCCCCHH
TMVREFKEETNLEVEVVRLLGVNGNLTLTYPNGDVAQWLCPVFLVKQLSGVLNSDNSETE
HHHHHHHHHCCCCEEEHEEECCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCHH
ALKFWDPAAAPDLFNQQHREVLAHFIANETGYFD
HEECCCCCCCCHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
ADYIKDIRTKVGHAPLIMAGVIGILTDQAGRVLLQQRSDFTGEWGLISGTIEYGETPAQ
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEECCCCCCCCCHH
TMVREFKEETNLEVEVVRLLGVNGNLTLTYPNGDVAQWLCPVFLVKQLSGVLNSDNSETE
HHHHHHHHHCCCCEEEHEEECCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHCCCCCCHH
ALKFWDPAAAPDLFNQQHREVLAHFIANETGYFD
HEECCCCCCCCHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: deoxy-ATP; H2O [C]

Specific reaction: deoxy-ATP + H2O = dAMP + pyrophosphate [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8631946 [H]