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The map label for this gene is licA [H]

Identifier: 116496240

GI number: 116496240

Start: 2801780

End: 2802109

Strand: Direct

Name: licA [H]

Synonym: LSEI_2818

Alternate gene names: 116496240

Gene position: 2801780-2802109 (Clockwise)

Preceding gene: 116496239

Following gene: 116496242

Centisome position: 96.77

GC content: 47.58

Gene sequence:

>330_bases
ATGAGTGAAGAAGATCAGAACCTCGAAACTGTCATGGGCTTGATCATGAATGGTGGCAACGCCAAGAGTTCTGCCTTTGA
AGCTATTCACGCAGCCAAAGCAGGCGATTTTGAAAAGGCCGACGAAAAGCTTAAAGAGTCCGACCACTTCCTGACCGAAG
CCCACAACGTTCAAACAGGCATGTTAACCGCTGAAGCCCAAGGCGATCATGCCGAGGTTACCTTGTTAATGGTTCACAGT
CAGGACCATCTGATGAATGCCATCACCTTCCGCGATTTAGCTGGTGAAATGGTTGATTTGTACAAACGATTAAGCGAGAA
AGAAGCCTAG

Upstream 100 bases:

>100_bases
ATGTGATTAACATGCAGGATTACGGCTTGATGAACGGCGAAAAAGTCCTCAAGGCGTCCTTGAAGGCAATTGCAGATGGT
AAACAAGGAGAAGAAGCATA

Downstream 100 bases:

>100_bases
GCAAACAAATAAGCCTTCGCCACGCGATGACGCATGAAGGCTTATTTGCAGTGGCCATTGTGAATAAACGGCTGTTATGA
AATCCCAAACAATCGCACCA

Product: cellobiose-specific PTS system IIA component

Products: protein histidine; sugar phosphate

Alternate protein names: EIIA-Lic; EIII-Lic; PTS system lichenan-specific EIIA component [H]

Number of amino acids: Translated: 109; Mature: 108

Protein sequence:

>109_residues
MSEEDQNLETVMGLIMNGGNAKSSAFEAIHAAKAGDFEKADEKLKESDHFLTEAHNVQTGMLTAEAQGDHAEVTLLMVHS
QDHLMNAITFRDLAGEMVDLYKRLSEKEA

Sequences:

>Translated_109_residues
MSEEDQNLETVMGLIMNGGNAKSSAFEAIHAAKAGDFEKADEKLKESDHFLTEAHNVQTGMLTAEAQGDHAEVTLLMVHS
QDHLMNAITFRDLAGEMVDLYKRLSEKEA
>Mature_108_residues
SEEDQNLETVMGLIMNGGNAKSSAFEAIHAAKAGDFEKADEKLKESDHFLTEAHNVQTGMLTAEAQGDHAEVTLLMVHSQ
DHLMNAITFRDLAGEMVDLYKRLSEKEA

Specific function: The phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane. This system i

COG id: COG1447

COG function: function code G; Phosphotransferase system cellobiose-specific component IIA

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PTS EIIA type-3 domain [H]

Homologues:

Organism=Escherichia coli, GI1788031, Length=96, Percent_Identity=42.7083333333333, Blast_Score=82, Evalue=1e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003188 [H]

Pfam domain/function: PF02255 PTS_IIA [H]

EC number: 2.7.1.69

Molecular weight: Translated: 12007; Mature: 11875

Theoretical pI: Translated: 4.43; Mature: 4.43

Prosite motif: PS51095 PTS_EIIA_TYPE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
6.4 %Met     (Translated Protein)
6.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
5.6 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEEDQNLETVMGLIMNGGNAKSSAFEAIHAAKAGDFEKADEKLKESDHFLTEAHNVQTG
CCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCC
MLTAEAQGDHAEVTLLMVHSQDHLMNAITFRDLAGEMVDLYKRLSEKEA
EEEECCCCCCCEEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SEEDQNLETVMGLIMNGGNAKSSAFEAIHAAKAGDFEKADEKLKESDHFLTEAHNVQTG
CCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCC
MLTAEAQGDHAEVTLLMVHSQDHLMNAITFRDLAGEMVDLYKRLSEKEA
EEEECCCCCCCEEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: protein N(pi)-phosphohistidine; sugar

Specific reaction: protein N(pi)-phosphohistidine + sugar = protein histidine + sugar phosphate

General reaction: Transferring phosphorus-containing groups [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8990303; 8969509; 9384377 [H]