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The map label for this gene is yceI [H]

Identifier: 116495729

GI number: 116495729

Start: 2275328

End: 2276533

Strand: Direct

Name: yceI [H]

Synonym: LSEI_2277

Alternate gene names: 116495729

Gene position: 2275328-2276533 (Clockwise)

Preceding gene: 116495726

Following gene: 116495734

Centisome position: 78.59

GC content: 50.41

Gene sequence:

>1206_bases
ATGTCAAAAAAACCGTCCGGCCATACGCGGCTGATCGTTGGCATCGGCGTTGCATGGCTGTTTGATGCCATGGATGTTGG
CATGTTAAGTTTCGTCATTGCGGCCTTACATAGCGAATGGCAATTAAGTACGGTGCAAATGGGCTGGATTGGCAGTGTCA
GTTCAATTGGGATGGCCGTTGGTGCCATTTTGTTCGGGATGATGGCGGACCGTTTTGGCCGTAAAGCGATCTTGATTCTT
ACTTTGCTAGTTTTTTCAATTGGCAGCGGCATTTCTGCCTTCGCCACAAGTTACGGCATTTTTCTTGGTTTGCGATTCAT
CATCGGTGCAGGCCTCGGTGGCGAGCTGCCAGTGGCATCAACCTTGGTTTCAGAAAGTGTGCCAGTTGAAAAACGTGGTC
GTAGTGTTGTCCTGTTGGAAAGTTTCTGGGCTGCCGGTTGGCTGTTAGCAGCCATTATTTCTTACTTCATTATGCCAATC
TGGGGCTGGCGCGTTGCCGTCTTTGCCACTGGTTTAGCCGGACTCTATGCGTTTTATTTTCGTGAAGGCATCAACGAATC
GCATGTCTTTAAAAAAGTGGCGCGGCCCGGCTTGCTCAAAACCCTCAGCACCCTTTGGCGCCCGCCTTATGTTCGCGCAA
CCTTGATGCTGTGGATCGTCTGGTTCATGGTAGTCTTCTCTTACTATGGCATGTTTCTTTGGCTGCCAAGTGTCATGGTA
CTCAAAGGATTTAGTCTGATTAATAGTTTTGGTTACGTCTTAATCATGACGCTTGCGCAGTTGCCTGGCTATTTCGTCGC
TGCTTGGTTAATTGAAAAATGGGGACGTAAAATGGTGCTGAGTCTGTTTCTGCTAGGCACAGCCGCCAGCGCATTAGGCT
TTGGCCTAGCCACCGGTTTGCCAATGCTACTGACTGCCGGCATGTTGCTCTCCTTCTTCAATCTCGGAGCTTGGGGCGCG
TTATACGCGTATTCTCCTGAACAATACCCAACTGTTGTCCGCAGCAGTGGTTCCGGTATGGCCGCCGGTATCGGCCGCAT
CGGTGGTGTGGTTGGACCGTTGTTAGTCGGTCATCTTTTGGGATCACACTGGTCAGTTGGCGGCATCTTTAGTATTTTCA
CCGCTGCCATCCTCATAGCAGTCCTAGCAATTATCTTCCTCGGCCAAGAAACCATGGGCGTGAAACTTGCCGACACGCTT
GAATAG

Upstream 100 bases:

>100_bases
ATATTGAAATTTTCATTGACATCACGGTTTGTTTTTGGTGAAATAGTAAACAAATCTAGGGTGTCAAGACACCCTAATCT
TCATTAAAGGAGGAGCGAAA

Downstream 100 bases:

>100_bases
TCTCAACAGACAACAAAAAAGCCTTGTAATTTGCGGGAATTCCCGCAGACTGCAAGGCTTTTTTACTGAAGTTAACGCCG
TAATGCGCGAGTAACCGTTT

Product: major facilitator superfamily permease

Products: Proton [Cytoplasm]; 3-(3-hydroxyphenyl)propionate [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 401; Mature: 400

Protein sequence:

>401_residues
MSKKPSGHTRLIVGIGVAWLFDAMDVGMLSFVIAALHSEWQLSTVQMGWIGSVSSIGMAVGAILFGMMADRFGRKAILIL
TLLVFSIGSGISAFATSYGIFLGLRFIIGAGLGGELPVASTLVSESVPVEKRGRSVVLLESFWAAGWLLAAIISYFIMPI
WGWRVAVFATGLAGLYAFYFREGINESHVFKKVARPGLLKTLSTLWRPPYVRATLMLWIVWFMVVFSYYGMFLWLPSVMV
LKGFSLINSFGYVLIMTLAQLPGYFVAAWLIEKWGRKMVLSLFLLGTAASALGFGLATGLPMLLTAGMLLSFFNLGAWGA
LYAYSPEQYPTVVRSSGSGMAAGIGRIGGVVGPLLVGHLLGSHWSVGGIFSIFTAAILIAVLAIIFLGQETMGVKLADTL
E

Sequences:

>Translated_401_residues
MSKKPSGHTRLIVGIGVAWLFDAMDVGMLSFVIAALHSEWQLSTVQMGWIGSVSSIGMAVGAILFGMMADRFGRKAILIL
TLLVFSIGSGISAFATSYGIFLGLRFIIGAGLGGELPVASTLVSESVPVEKRGRSVVLLESFWAAGWLLAAIISYFIMPI
WGWRVAVFATGLAGLYAFYFREGINESHVFKKVARPGLLKTLSTLWRPPYVRATLMLWIVWFMVVFSYYGMFLWLPSVMV
LKGFSLINSFGYVLIMTLAQLPGYFVAAWLIEKWGRKMVLSLFLLGTAASALGFGLATGLPMLLTAGMLLSFFNLGAWGA
LYAYSPEQYPTVVRSSGSGMAAGIGRIGGVVGPLLVGHLLGSHWSVGGIFSIFTAAILIAVLAIIFLGQETMGVKLADTL
E
>Mature_400_residues
SKKPSGHTRLIVGIGVAWLFDAMDVGMLSFVIAALHSEWQLSTVQMGWIGSVSSIGMAVGAILFGMMADRFGRKAILILT
LLVFSIGSGISAFATSYGIFLGLRFIIGAGLGGELPVASTLVSESVPVEKRGRSVVLLESFWAAGWLLAAIISYFIMPIW
GWRVAVFATGLAGLYAFYFREGINESHVFKKVARPGLLKTLSTLWRPPYVRATLMLWIVWFMVVFSYYGMFLWLPSVMVL
KGFSLINSFGYVLIMTLAQLPGYFVAAWLIEKWGRKMVLSLFLLGTAASALGFGLATGLPMLLTAGMLLSFFNLGAWGAL
YAYSPEQYPTVVRSSGSGMAAGIGRIGGVVGPLLVGHLLGSHWSVGGIFSIFTAAILIAVLAIIFLGQETMGVKLADTLE

Specific function: Could Be A Transporter For 3-Phenylpropionate (Hydrocinnamic Acid). [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family [H]

Homologues:

Organism=Homo sapiens, GI24308167, Length=440, Percent_Identity=29.5454545454545, Blast_Score=167, Evalue=2e-41,
Organism=Homo sapiens, GI213021148, Length=452, Percent_Identity=25.6637168141593, Blast_Score=114, Evalue=1e-25,
Organism=Homo sapiens, GI166064021, Length=407, Percent_Identity=25.5528255528256, Blast_Score=100, Evalue=4e-21,
Organism=Homo sapiens, GI90669191, Length=395, Percent_Identity=27.5949367088608, Blast_Score=99, Evalue=6e-21,
Organism=Homo sapiens, GI24497497, Length=395, Percent_Identity=27.5949367088608, Blast_Score=99, Evalue=1e-20,
Organism=Homo sapiens, GI7662270, Length=164, Percent_Identity=34.7560975609756, Blast_Score=94, Evalue=2e-19,
Organism=Homo sapiens, GI216548223, Length=164, Percent_Identity=35.3658536585366, Blast_Score=88, Evalue=1e-17,
Organism=Homo sapiens, GI24497490, Length=416, Percent_Identity=24.0384615384615, Blast_Score=81, Evalue=2e-15,
Organism=Homo sapiens, GI166197673, Length=377, Percent_Identity=27.3209549071618, Blast_Score=81, Evalue=2e-15,
Organism=Homo sapiens, GI31542327, Length=391, Percent_Identity=25.3196930946292, Blast_Score=81, Evalue=2e-15,
Organism=Homo sapiens, GI73695465, Length=164, Percent_Identity=32.3170731707317, Blast_Score=80, Evalue=3e-15,
Organism=Homo sapiens, GI262399383, Length=108, Percent_Identity=39.8148148148148, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI4507005, Length=419, Percent_Identity=23.3890214797136, Blast_Score=77, Evalue=2e-14,
Organism=Escherichia coli, GI87081723, Length=373, Percent_Identity=30.5630026809651, Blast_Score=131, Evalue=6e-32,
Organism=Escherichia coli, GI87082404, Length=387, Percent_Identity=25.3229974160207, Blast_Score=116, Evalue=2e-27,
Organism=Escherichia coli, GI87082231, Length=174, Percent_Identity=30.4597701149425, Blast_Score=92, Evalue=6e-20,
Organism=Escherichia coli, GI87082159, Length=375, Percent_Identity=26.4, Blast_Score=85, Evalue=8e-18,
Organism=Escherichia coli, GI1788068, Length=385, Percent_Identity=23.8961038961039, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI1788074, Length=388, Percent_Identity=25, Blast_Score=76, Evalue=3e-15,
Organism=Escherichia coli, GI1786229, Length=431, Percent_Identity=22.969837587007, Blast_Score=73, Evalue=4e-14,
Organism=Escherichia coli, GI1790550, Length=343, Percent_Identity=24.4897959183673, Blast_Score=63, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI32564663, Length=444, Percent_Identity=28.3783783783784, Blast_Score=163, Evalue=1e-40,
Organism=Caenorhabditis elegans, GI193209824, Length=402, Percent_Identity=24.3781094527363, Blast_Score=81, Evalue=9e-16,
Organism=Caenorhabditis elegans, GI71986689, Length=442, Percent_Identity=24.6606334841629, Blast_Score=75, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI193202825, Length=442, Percent_Identity=24.6606334841629, Blast_Score=75, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI71996338, Length=210, Percent_Identity=29.5238095238095, Blast_Score=70, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17542342, Length=412, Percent_Identity=23.3009708737864, Blast_Score=69, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI71980822, Length=358, Percent_Identity=24.8603351955307, Blast_Score=67, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI193207197, Length=414, Percent_Identity=24.1545893719807, Blast_Score=65, Evalue=8e-11,
Organism=Drosophila melanogaster, GI19922874, Length=432, Percent_Identity=25.9259259259259, Blast_Score=151, Evalue=6e-37,
Organism=Drosophila melanogaster, GI19922616, Length=412, Percent_Identity=28.6407766990291, Blast_Score=102, Evalue=4e-22,
Organism=Drosophila melanogaster, GI24640198, Length=457, Percent_Identity=23.6323851203501, Blast_Score=99, Evalue=5e-21,
Organism=Drosophila melanogaster, GI24640196, Length=457, Percent_Identity=23.6323851203501, Blast_Score=99, Evalue=5e-21,
Organism=Drosophila melanogaster, GI24640200, Length=457, Percent_Identity=23.6323851203501, Blast_Score=99, Evalue=5e-21,
Organism=Drosophila melanogaster, GI24649618, Length=413, Percent_Identity=24.455205811138, Blast_Score=90, Evalue=2e-18,
Organism=Drosophila melanogaster, GI24649616, Length=362, Percent_Identity=24.8618784530387, Blast_Score=86, Evalue=6e-17,
Organism=Drosophila melanogaster, GI24649622, Length=401, Percent_Identity=24.1895261845387, Blast_Score=80, Evalue=3e-15,
Organism=Drosophila melanogaster, GI21355657, Length=421, Percent_Identity=25.41567695962, Blast_Score=79, Evalue=4e-15,
Organism=Drosophila melanogaster, GI62484254, Length=420, Percent_Identity=23.8095238095238, Blast_Score=69, Evalue=6e-12,
Organism=Drosophila melanogaster, GI24668456, Length=389, Percent_Identity=23.3933161953728, Blast_Score=69, Evalue=7e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196
- InterPro:   IPR005829 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 43203; Mature: 43072

Theoretical pI: Translated: 10.21; Mature: 10.21

Prosite motif: PS50850 MFS ; PS00217 SUGAR_TRANSPORT_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKKPSGHTRLIVGIGVAWLFDAMDVGMLSFVIAALHSEWQLSTVQMGWIGSVSSIGMAV
CCCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHH
GAILFGMMADRFGRKAILILTLLVFSIGSGISAFATSYGIFLGLRFIIGAGLGGELPVAS
HHHHHHHHHHHHCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHH
TLVSESVPVEKRGRSVVLLESFWAAGWLLAAIISYFIMPIWGWRVAVFATGLAGLYAFYF
HHHHCCCCHHHCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
REGINESHVFKKVARPGLLKTLSTLWRPPYVRATLMLWIVWFMVVFSYYGMFLWLPSVMV
HHCCCHHHHHHHHHCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LKGFSLINSFGYVLIMTLAQLPGYFVAAWLIEKWGRKMVLSLFLLGTAASALGFGLATGL
HHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
PMLLTAGMLLSFFNLGAWGALYAYSPEQYPTVVRSSGSGMAAGIGRIGGVVGPLLVGHLL
HHHHHHHHHHHHHHCCCCHHHEECCCHHCCHHHHCCCCCHHHHHHHHHHHHHHHHHHHHH
GSHWSVGGIFSIFTAAILIAVLAIIFLGQETMGVKLADTLE
HCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHCCEEHHCCCC
>Mature Secondary Structure 
SKKPSGHTRLIVGIGVAWLFDAMDVGMLSFVIAALHSEWQLSTVQMGWIGSVSSIGMAV
CCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHH
GAILFGMMADRFGRKAILILTLLVFSIGSGISAFATSYGIFLGLRFIIGAGLGGELPVAS
HHHHHHHHHHHHCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHH
TLVSESVPVEKRGRSVVLLESFWAAGWLLAAIISYFIMPIWGWRVAVFATGLAGLYAFYF
HHHHCCCCHHHCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
REGINESHVFKKVARPGLLKTLSTLWRPPYVRATLMLWIVWFMVVFSYYGMFLWLPSVMV
HHCCCHHHHHHHHHCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LKGFSLINSFGYVLIMTLAQLPGYFVAAWLIEKWGRKMVLSLFLLGTAASALGFGLATGL
HHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
PMLLTAGMLLSFFNLGAWGALYAYSPEQYPTVVRSSGSGMAAGIGRIGGVVGPLLVGHLL
HHHHHHHHHHHHHHCCCCHHHEECCCHHCCHHHHCCCCCHHHHHHHHHHHHHHHHHHHHH
GSHWSVGGIFSIFTAAILIAVLAIIFLGQETMGVKLADTLE
HCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHCCEEHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; 3-(3-hydroxyphenyl)propionate [Periplasm] [C]

Specific reaction: Proton [Periplasm] + 3-(3-hydroxyphenyl)propionate [Periplasm] = Proton [Cytoplasm] + 3-(3-hydroxyphenyl)propionate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9274031; 9384377 [H]