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The map label for this gene is murA2 [H]

Identifier: 116493298

GI number: 116493298

Start: 1538814

End: 1540085

Strand: Reverse

Name: murA2 [H]

Synonym: PEPE_1570

Alternate gene names: 116493298

Gene position: 1540085-1538814 (Counterclockwise)

Preceding gene: 116493299

Following gene: 116493297

Centisome position: 84.05

GC content: 40.49

Gene sequence:

>1272_bases
ATGAAAAAAATGATAATCAAGGGTGGACAGCGACTGTCTGGAGAAGTGACCATCGGTGGTGCTAAAAATAGTACCGTTGC
GTTGATTCCGGCTGCAATTTTGGCGGATACTCCAGTACGGTTTGATTCAGTGCCCGACATACTTGACGTGCATAACTTAA
TGATTATCCTTGAATCGATGAATGTTCATTCAACGTTTGAGGATGGAGTTATGGTGATTGATCCAACTGAAATTGTTGAG
AATCCATTGCCTAGTAAGGCAATTAAGAGCTTACGAGCATCATATTACTTTATGGGCTCTTTACTTGGTCGTTTCAAGCG
TTCAACAGTTACATTTCCAGGTGGAGATAATATTGGTCCAAGACCAATTGATCAGCATATTAAAGGCTTCAAAGCCTTAG
GTGCCAACGTTACAGAAGATGAAGATACAGTGTACATTTCAGCATATGATCGTGGACTCCATGGAGCGCACATCTTTTTA
GATGTGGTTTCTGTAGGAGCAACGATCAATGTTATTTTGGCTGCCGTTAAGGCCCAAGGTATTACAACGATTGAAAACGC
AGCACGTGAACCCGAGATTATTGATTTAGCAATGTTTTTAAATAATATGGGGGCTAAAATTCGTGGAGCAGGGACTGATG
TTATCCGAATTGAAGGTGTAGATAAGTTGGTTTCTACAGCTACGCATACCATTATTCCGGATCGAATTGAGGCTGGAACC
TATTTGTCTTTAGCTACGGCTGTGGGGGATGGTGTGATGGTAAATAATATTATTCCAGAACACCTAGAATCGTTTACTTC
AAAGATGCTTGAACTTGGCGTCGATATTAAAATTGATGGCGATAAGATTTTTGTTCCTAAAGTGGATCAATTAAAAGCAA
TTGAAGTCAATACGAGTCCTTTCCCTGGATTTGCGACTGATTTGCAACAACCTTTGACGGCTTCCCTATTAAAAGCAACT
GGTCAAAGTGTTGTTAATGATCATATTTATCCAGAACGTATCAAACACGTAATTGAATTACAAAAAATGGGTGCTAAGAT
TAAACATGCTGATGGAGTGATTTATATTAATCATTCTGAAAAACTTACGGGCGCTGAAGTTGAGGCTGGAGAAATTCGGG
CAGGGGCTTGTTTAATGATTGCAGCCTTTATGGCCCAAGGCACTACAACCATCACCCGAGCAGATAACATCCTACGTGGA
TACGACAGTTTGGTTAAAAAACTAACTAAGCTCGGAGCGGATGTTTCAATCACGACCGACAATACATTGTAG

Upstream 100 bases:

>100_bases
TGAGGTTGTATTTTTGGAACAAATTATTTATGATTGAGGTTGACTGTAAAATACATTCCTTAATTTTAAAGTACTTAAAG
TTCGTTTGTGAGGAAAAACC

Downstream 100 bases:

>100_bases
TCAAAGATATAGGAGAGTTAAGTCGATGGATAATTTTTTAACAATGAATGACTTGCAAGAAATGACTCTCAAAGAAATAT
ACGGCCTTGCCCGTGAATAT

Product: UDP-N-acetylglucosamine 1-carboxyvinyltransferase

Products: NA

Alternate protein names: Enoylpyruvate transferase 2; UDP-N-acetylglucosamine enolpyruvyl transferase 2; EPT 2 [H]

Number of amino acids: Translated: 423; Mature: 423

Protein sequence:

>423_residues
MKKMIIKGGQRLSGEVTIGGAKNSTVALIPAAILADTPVRFDSVPDILDVHNLMIILESMNVHSTFEDGVMVIDPTEIVE
NPLPSKAIKSLRASYYFMGSLLGRFKRSTVTFPGGDNIGPRPIDQHIKGFKALGANVTEDEDTVYISAYDRGLHGAHIFL
DVVSVGATINVILAAVKAQGITTIENAAREPEIIDLAMFLNNMGAKIRGAGTDVIRIEGVDKLVSTATHTIIPDRIEAGT
YLSLATAVGDGVMVNNIIPEHLESFTSKMLELGVDIKIDGDKIFVPKVDQLKAIEVNTSPFPGFATDLQQPLTASLLKAT
GQSVVNDHIYPERIKHVIELQKMGAKIKHADGVIYINHSEKLTGAEVEAGEIRAGACLMIAAFMAQGTTTITRADNILRG
YDSLVKKLTKLGADVSITTDNTL

Sequences:

>Translated_423_residues
MKKMIIKGGQRLSGEVTIGGAKNSTVALIPAAILADTPVRFDSVPDILDVHNLMIILESMNVHSTFEDGVMVIDPTEIVE
NPLPSKAIKSLRASYYFMGSLLGRFKRSTVTFPGGDNIGPRPIDQHIKGFKALGANVTEDEDTVYISAYDRGLHGAHIFL
DVVSVGATINVILAAVKAQGITTIENAAREPEIIDLAMFLNNMGAKIRGAGTDVIRIEGVDKLVSTATHTIIPDRIEAGT
YLSLATAVGDGVMVNNIIPEHLESFTSKMLELGVDIKIDGDKIFVPKVDQLKAIEVNTSPFPGFATDLQQPLTASLLKAT
GQSVVNDHIYPERIKHVIELQKMGAKIKHADGVIYINHSEKLTGAEVEAGEIRAGACLMIAAFMAQGTTTITRADNILRG
YDSLVKKLTKLGADVSITTDNTL
>Mature_423_residues
MKKMIIKGGQRLSGEVTIGGAKNSTVALIPAAILADTPVRFDSVPDILDVHNLMIILESMNVHSTFEDGVMVIDPTEIVE
NPLPSKAIKSLRASYYFMGSLLGRFKRSTVTFPGGDNIGPRPIDQHIKGFKALGANVTEDEDTVYISAYDRGLHGAHIFL
DVVSVGATINVILAAVKAQGITTIENAAREPEIIDLAMFLNNMGAKIRGAGTDVIRIEGVDKLVSTATHTIIPDRIEAGT
YLSLATAVGDGVMVNNIIPEHLESFTSKMLELGVDIKIDGDKIFVPKVDQLKAIEVNTSPFPGFATDLQQPLTASLLKAT
GQSVVNDHIYPERIKHVIELQKMGAKIKHADGVIYINHSEKLTGAEVEAGEIRAGACLMIAAFMAQGTTTITRADNILRG
YDSLVKKLTKLGADVSITTDNTL

Specific function: Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine [H]

COG id: COG0766

COG function: function code M; UDP-N-acetylglucosamine enolpyruvyl transferase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the EPSP synthase family. MurA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789580, Length=417, Percent_Identity=40.5275779376499, Blast_Score=291, Evalue=6e-80,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001986
- InterPro:   IPR013792
- InterPro:   IPR005750 [H]

Pfam domain/function: PF00275 EPSP_synthase [H]

EC number: =2.5.1.7 [H]

Molecular weight: Translated: 45437; Mature: 45437

Theoretical pI: Translated: 5.97; Mature: 5.97

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKMIIKGGQRLSGEVTIGGAKNSTVALIPAAILADTPVRFDSVPDILDVHNLMIILESM
CCCCEECCCCEECCEEEECCCCCCEEEEEEHHHHCCCCCCCCCCCCHHHHHHHHEEEECC
NVHSTFEDGVMVIDPTEIVENPLPSKAIKSLRASYYFMGSLLGRFKRSTVTFPGGDNIGP
CCCCCCCCCEEEECCHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCEEECCCCCCCCC
RPIDQHIKGFKALGANVTEDEDTVYISAYDRGLHGAHIFLDVVSVGATINVILAAVKAQG
CCHHHHHHHHHHHCCCCCCCCCEEEEEEECCCCCHHHHHHHHHHHCHHHHHHHHHHHHCC
ITTIENAAREPEIIDLAMFLNNMGAKIRGAGTDVIRIEGVDKLVSTATHTIIPDRIEAGT
CHHHHHHCCCCCHHHHHHHHHHCCCEEECCCCCEEEECCHHHHHHHHHHHCCCCCCCCCC
YLSLATAVGDGVMVNNIIPEHLESFTSKMLELGVDIKIDGDKIFVPKVDQLKAIEVNTSP
CEEHHHHHCCCEEECCCCHHHHHHHHHHHHHCCCEEEECCCEEECCCCCCEEEEEECCCC
FPGFATDLQQPLTASLLKATGQSVVNDHIYPERIKHVIELQKMGAKIKHADGVIYINHSE
CCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCEEECCCEEEEECCC
KLTGAEVEAGEIRAGACLMIAAFMAQGTTTITRADNILRGYDSLVKKLTKLGADVSITTD
CCCCCCCCCCCCCCCHHHHHHHHHHCCCEEEHHHHHHHHHHHHHHHHHHHCCCCEEEECC
NTL
CCC
>Mature Secondary Structure
MKKMIIKGGQRLSGEVTIGGAKNSTVALIPAAILADTPVRFDSVPDILDVHNLMIILESM
CCCCEECCCCEECCEEEECCCCCCEEEEEEHHHHCCCCCCCCCCCCHHHHHHHHEEEECC
NVHSTFEDGVMVIDPTEIVENPLPSKAIKSLRASYYFMGSLLGRFKRSTVTFPGGDNIGP
CCCCCCCCCEEEECCHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCEEECCCCCCCCC
RPIDQHIKGFKALGANVTEDEDTVYISAYDRGLHGAHIFLDVVSVGATINVILAAVKAQG
CCHHHHHHHHHHHCCCCCCCCCEEEEEEECCCCCHHHHHHHHHHHCHHHHHHHHHHHHCC
ITTIENAAREPEIIDLAMFLNNMGAKIRGAGTDVIRIEGVDKLVSTATHTIIPDRIEAGT
CHHHHHHCCCCCHHHHHHHHHHCCCEEECCCCCEEEECCHHHHHHHHHHHCCCCCCCCCC
YLSLATAVGDGVMVNNIIPEHLESFTSKMLELGVDIKIDGDKIFVPKVDQLKAIEVNTSP
CEEHHHHHCCCEEECCCCHHHHHHHHHHHHHCCCEEEECCCEEECCCCCCEEEEEECCCC
FPGFATDLQQPLTASLLKATGQSVVNDHIYPERIKHVIELQKMGAKIKHADGVIYINHSE
CCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCEEECCCEEEEECCC
KLTGAEVEAGEIRAGACLMIAAFMAQGTTTITRADNILRGYDSLVKKLTKLGADVSITTD
CCCCCCCCCCCCCCCHHHHHHHHHHCCCEEEHHHHHHHHHHHHHHHHHHHCCCCEEEECC
NTL
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12566566 [H]