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The map label for this gene is ruvB

Identifier: 116493019

GI number: 116493019

Start: 1258348

End: 1259361

Strand: Reverse

Name: ruvB

Synonym: PEPE_1271

Alternate gene names: 116493019

Gene position: 1259361-1258348 (Counterclockwise)

Preceding gene: 116493020

Following gene: 116493018

Centisome position: 68.73

GC content: 40.83

Gene sequence:

>1014_bases
ATGGAAGATGAACGGATTACTTCTGCGGAAGTTCAAAGTCCAGACGAAGAAAATGAAGAGTTGTCGTTAAGGCCTCAAAC
ATTGCATCAATATATTGGTCAGGATCAGATTAAACATGAGCTTGAAGTATATATTGCCGCAGCCAAAAATCGCGAAGAAG
CACTAGATCATGTTCTTTTATATGGCCCCCCTGGACTAGGGAAAACGACTTTAGCGATGGTTATTGCTAATGAAATGAAC
GTTCAGATTCGAACGACTAGTGGACCAGCCATTGAAAAACCGGGTGATTTAGTAGCTCTTTTGAATGAGCTACAACCTGG
TGACGTTTTATTTATTGATGAAATTCATCGATTACCTAAAGTGGTGGAGGAAATGCTCTATTCAGCCATGGAAGATTTCT
TTGTTGATATTGTTGTCGGACAAGGACCAACTGCACATCCAATTCATTTTCCTTTACCACCTTTCACTTTGATTGGAGCG
ACTACTAGAGCGGGCTTACTCTCAGCTCCATTACGAGATCGCTTTGGAATTGTTGAACATATGAATTACTATAATGAAGC
GGATTTAGCTAACATTGTTCGACGCTCTGCGGGTATTTTTAACTCGCATATTGACGATCAAGGGGCGTACGAAATTGCTA
GTCGCTCACGAGGAACACCGCGAATTTCGAATCGTCTGTTAAAACGAATCCGAGATTTTGCTGAAGTAGAAAATGATGGA
CAAATTGATCGCCAATTGGTTAGTCAGTCCTTGAAATTACTTCAAGTAGATAATCGTGGACTAGATCGGACTGATAAAAA
AGTTCTAACTACTATGATCGAGCTCTATGGAGGCGGTCCGGTAGGAATTTCCACCATTGCAGCTAATATCGGTGAAGAAC
CAGATACTATTTCAGAAATGTATGAACCATACTTGCTTCAAATTGGATTCCTGAAAAGGACGCCTCGAGGCCGGATGGTT
ACAGAACGTGCCTACGAACATCTAGGCTTAATTGATCAATATATGAATAAATGA

Upstream 100 bases:

>100_bases
TAAGAAATTAACTAAGAAATTGAGTGAACAAACTGATCGGACAACTGATCAGTATATTAGTTCGGGATTAAAATTATTGA
TGAAAGGATAAGACAAGTTG

Downstream 100 bases:

>100_bases
GGAATTGAAAATGACACTAACTACTGAAGATTTTAATTATGACTTACCACATGAATTAATTGCCCAAACTCCAATTAAAG
AACGCGATGAATCTCGTTTA

Product: Holliday junction DNA helicase RuvB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 337; Mature: 337

Protein sequence:

>337_residues
MEDERITSAEVQSPDEENEELSLRPQTLHQYIGQDQIKHELEVYIAAAKNREEALDHVLLYGPPGLGKTTLAMVIANEMN
VQIRTTSGPAIEKPGDLVALLNELQPGDVLFIDEIHRLPKVVEEMLYSAMEDFFVDIVVGQGPTAHPIHFPLPPFTLIGA
TTRAGLLSAPLRDRFGIVEHMNYYNEADLANIVRRSAGIFNSHIDDQGAYEIASRSRGTPRISNRLLKRIRDFAEVENDG
QIDRQLVSQSLKLLQVDNRGLDRTDKKVLTTMIELYGGGPVGISTIAANIGEEPDTISEMYEPYLLQIGFLKRTPRGRMV
TERAYEHLGLIDQYMNK

Sequences:

>Translated_337_residues
MEDERITSAEVQSPDEENEELSLRPQTLHQYIGQDQIKHELEVYIAAAKNREEALDHVLLYGPPGLGKTTLAMVIANEMN
VQIRTTSGPAIEKPGDLVALLNELQPGDVLFIDEIHRLPKVVEEMLYSAMEDFFVDIVVGQGPTAHPIHFPLPPFTLIGA
TTRAGLLSAPLRDRFGIVEHMNYYNEADLANIVRRSAGIFNSHIDDQGAYEIASRSRGTPRISNRLLKRIRDFAEVENDG
QIDRQLVSQSLKLLQVDNRGLDRTDKKVLTTMIELYGGGPVGISTIAANIGEEPDTISEMYEPYLLQIGFLKRTPRGRMV
TERAYEHLGLIDQYMNK
>Mature_337_residues
MEDERITSAEVQSPDEENEELSLRPQTLHQYIGQDQIKHELEVYIAAAKNREEALDHVLLYGPPGLGKTTLAMVIANEMN
VQIRTTSGPAIEKPGDLVALLNELQPGDVLFIDEIHRLPKVVEEMLYSAMEDFFVDIVVGQGPTAHPIHFPLPPFTLIGA
TTRAGLLSAPLRDRFGIVEHMNYYNEADLANIVRRSAGIFNSHIDDQGAYEIASRSRGTPRISNRLLKRIRDFAEVENDG
QIDRQLVSQSLKLLQVDNRGLDRTDKKVLTTMIELYGGGPVGISTIAANIGEEPDTISEMYEPYLLQIGFLKRTPRGRMV
TERAYEHLGLIDQYMNK

Specific function: The ruvA-ruvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is an helicase that mediates the Holliday

COG id: COG2255

COG function: function code L; Holliday junction resolvasome, helicase subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ruvB family

Homologues:

Organism=Escherichia coli, GI1788167, Length=330, Percent_Identity=56.0606060606061, Blast_Score=387, Evalue=1e-109,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RUVB_PEDPA (Q03ER0)

Other databases:

- EMBL:   CP000422
- RefSeq:   YP_804754.1
- ProteinModelPortal:   Q03ER0
- SMR:   Q03ER0
- STRING:   Q03ER0
- GeneID:   4417607
- GenomeReviews:   CP000422_GR
- KEGG:   ppe:PEPE_1271
- NMPDR:   fig|278197.10.peg.1113
- eggNOG:   COG2255
- HOGENOM:   HBG339960
- OMA:   EKFDGGP
- PhylomeDB:   Q03ER0
- ProtClustDB:   PRK00080
- BioCyc:   PPEN278197:PEPE_1271-MONOMER
- HAMAP:   MF_00016
- InterPro:   IPR003593
- InterPro:   IPR004605
- InterPro:   IPR008823
- InterPro:   IPR008824
- InterPro:   IPR011991
- Gene3D:   G3DSA:1.10.10.10
- ProDom:   PD005323
- SMART:   SM00382
- TIGRFAMs:   TIGR00635

Pfam domain/function: PF05491 RuvB_C; PF05496 RuvB_N

EC number: =3.6.4.12

Molecular weight: Translated: 37804; Mature: 37804

Theoretical pI: Translated: 4.75; Mature: 4.75

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEDERITSAEVQSPDEENEELSLRPQTLHQYIGQDQIKHELEVYIAAAKNREEALDHVLL
CCCCCCCHHHCCCCCCCCCCCCCCHHHHHHHHCHHHHHHHHHHHEEHHCCHHHHHCEEEE
YGPPGLGKTTLAMVIANEMNVQIRTTSGPAIEKPGDLVALLNELQPGDVLFIDEIHRLPK
ECCCCCCHHHHHHHEECCCEEEEEECCCCCCCCCCHHHHHHHHCCCCCEEEHHHHHHHHH
VVEEMLYSAMEDFFVDIVVGQGPTAHPIHFPLPPFTLIGATTRAGLLSAPLRDRFGIVEH
HHHHHHHHHHHHHHEEEEECCCCCCCCCCCCCCCHHHHCCHHHHHHHHCCHHHHHHHHHH
MNYYNEADLANIVRRSAGIFNSHIDDQGAYEIASRSRGTPRISNRLLKRIRDFAEVENDG
HHHCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCC
QIDRQLVSQSLKLLQVDNRGLDRTDKKVLTTMIELYGGGPVGISTIAANIGEEPDTISEM
HHHHHHHHHHHHHEEECCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCHHHHHH
YEPYLLQIGFLKRTPRGRMVTERAYEHLGLIDQYMNK
HHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MEDERITSAEVQSPDEENEELSLRPQTLHQYIGQDQIKHELEVYIAAAKNREEALDHVLL
CCCCCCCHHHCCCCCCCCCCCCCCHHHHHHHHCHHHHHHHHHHHEEHHCCHHHHHCEEEE
YGPPGLGKTTLAMVIANEMNVQIRTTSGPAIEKPGDLVALLNELQPGDVLFIDEIHRLPK
ECCCCCCHHHHHHHEECCCEEEEEECCCCCCCCCCHHHHHHHHCCCCCEEEHHHHHHHHH
VVEEMLYSAMEDFFVDIVVGQGPTAHPIHFPLPPFTLIGATTRAGLLSAPLRDRFGIVEH
HHHHHHHHHHHHHHEEEEECCCCCCCCCCCCCCCHHHHCCHHHHHHHHCCHHHHHHHHHH
MNYYNEADLANIVRRSAGIFNSHIDDQGAYEIASRSRGTPRISNRLLKRIRDFAEVENDG
HHHCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCC
QIDRQLVSQSLKLLQVDNRGLDRTDKKVLTTMIELYGGGPVGISTIAANIGEEPDTISEM
HHHHHHHHHHHHHEEECCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCHHHHHH
YEPYLLQIGFLKRTPRGRMVTERAYEHLGLIDQYMNK
HHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA