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The map label for this gene is ruvA

Identifier: 116493020

GI number: 116493020

Start: 1259371

End: 1259958

Strand: Reverse

Name: ruvA

Synonym: PEPE_1272

Alternate gene names: 116493020

Gene position: 1259958-1259371 (Counterclockwise)

Preceding gene: 116493021

Following gene: 116493019

Centisome position: 68.76

GC content: 32.82

Gene sequence:

>588_bases
ATGTATGAATATTTAGATGGAGTCGTCGTTAACGTTAATCCAGCTTATATTGTTGTTGATGTCAATGGAGTTGGATTTTT
AGTTAACGTGGCTAATCCATATAGTTTTGAACTAGATGCTAAACAGAAAGTTTTTGTTCATCAAGCTGTTTCAGAAAATG
ATCAAACTTTATATGGATTTAAAAAAGCTGAAGATAAAGAACTTTTTCTTAATTTATTAAAAGTTAAGGGGATTGGTCCG
AAAAGTGCGTTGGCTATTTTAGCGAACGATGATCATACAGGGTTGATTAATGCGATTAATAATGATGATGTAAGTTATCT
CAAAAAGTTCCCTAAGATTGGTCCTAAGGCTGCTCAACAAATCATTCTAGATTTGAAGGGCAAAGTGGCGGTTGAAAATG
AAGTAGGAACCCTTTTTGATTTATCAACTACTTCAAACCAAGCTCTAGATGAAGCTCTAGAAGCTTTGATTGCATTAGGT
TATTCTGAAAAAGAGGTTAAGAAATTAACTAAGAAATTGAGTGAACAAACTGATCGGACAACTGATCAGTATATTAGTTC
GGGATTAAAATTATTGATGAAAGGATAA

Upstream 100 bases:

>100_bases
TTAAAAGAATTCAAGATCCACACCATTCTGACTTGATGGAAGATGAGATGTGATACAATTAACTGAATGCGAACAAACGT
TTTGAAATGAGGATTTATAA

Downstream 100 bases:

>100_bases
GACAAGTTGATGGAAGATGAACGGATTACTTCTGCGGAAGTTCAAAGTCCAGACGAAGAAAATGAAGAGTTGTCGTTAAG
GCCTCAAACATTGCATCAAT

Product: Holliday junction DNA helicase subunit RuvA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 195; Mature: 195

Protein sequence:

>195_residues
MYEYLDGVVVNVNPAYIVVDVNGVGFLVNVANPYSFELDAKQKVFVHQAVSENDQTLYGFKKAEDKELFLNLLKVKGIGP
KSALAILANDDHTGLINAINNDDVSYLKKFPKIGPKAAQQIILDLKGKVAVENEVGTLFDLSTTSNQALDEALEALIALG
YSEKEVKKLTKKLSEQTDRTTDQYISSGLKLLMKG

Sequences:

>Translated_195_residues
MYEYLDGVVVNVNPAYIVVDVNGVGFLVNVANPYSFELDAKQKVFVHQAVSENDQTLYGFKKAEDKELFLNLLKVKGIGP
KSALAILANDDHTGLINAINNDDVSYLKKFPKIGPKAAQQIILDLKGKVAVENEVGTLFDLSTTSNQALDEALEALIALG
YSEKEVKKLTKKLSEQTDRTTDQYISSGLKLLMKG
>Mature_195_residues
MYEYLDGVVVNVNPAYIVVDVNGVGFLVNVANPYSFELDAKQKVFVHQAVSENDQTLYGFKKAEDKELFLNLLKVKGIGP
KSALAILANDDHTGLINAINNDDVSYLKKFPKIGPKAAQQIILDLKGKVAVENEVGTLFDLSTTSNQALDEALEALIALG
YSEKEVKKLTKKLSEQTDRTTDQYISSGLKLLMKG

Specific function: The ruvA-ruvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is an helicase that mediates the Holliday

COG id: COG0632

COG function: function code L; Holliday junction resolvasome, DNA-binding subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ruvA family

Homologues:

Organism=Escherichia coli, GI1788168, Length=203, Percent_Identity=33.9901477832512, Blast_Score=110, Evalue=5e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RUVA_PEDPA (Q03EQ9)

Other databases:

- EMBL:   CP000422
- RefSeq:   YP_804755.1
- ProteinModelPortal:   Q03EQ9
- SMR:   Q03EQ9
- STRING:   Q03EQ9
- GeneID:   4417608
- GenomeReviews:   CP000422_GR
- KEGG:   ppe:PEPE_1272
- NMPDR:   fig|278197.10.peg.1114
- eggNOG:   COG0632
- HOGENOM:   HBG635309
- OMA:   LSIETYV
- PhylomeDB:   Q03EQ9
- BioCyc:   PPEN278197:PEPE_1272-MONOMER
- HAMAP:   MF_00031
- InterPro:   IPR011114
- InterPro:   IPR013849
- InterPro:   IPR003583
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR000085
- InterPro:   IPR010994
- Gene3D:   G3DSA:2.40.50.140
- SMART:   SM00278
- TIGRFAMs:   TIGR00084

Pfam domain/function: PF07499 RuvA_C; PF01330 RuvA_N; SSF50249 Nucleic_acid_OB; SSF47781 RuvA_2_like; SSF46929 RuvA_C-like

EC number: =3.6.4.12

Molecular weight: Translated: 21397; Mature: 21397

Theoretical pI: Translated: 5.07; Mature: 5.07

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYEYLDGVVVNVNPAYIVVDVNGVGFLVNVANPYSFELDAKQKVFVHQAVSENDQTLYGF
CCCCCCCEEEECCCEEEEEEECCCEEEEECCCCEEEEECCCHHHHHHHHHCCCCCEEECC
KKAEDKELFLNLLKVKGIGPKSALAILANDDHTGLINAINNDDVSYLKKFPKIGPKAAQQ
CCCCCHHHHHHHHHHCCCCCCCEEEEEECCCCCEEEEECCCCCHHHHHHCCCCCHHHHHH
IILDLKGKVAVENEVGTLFDLSTTSNQALDEALEALIALGYSEKEVKKLTKKLSEQTDRT
HHHHCCCCEEEECCCCEEEEECCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCH
TDQYISSGLKLLMKG
HHHHHHHHHHHEECC
>Mature Secondary Structure
MYEYLDGVVVNVNPAYIVVDVNGVGFLVNVANPYSFELDAKQKVFVHQAVSENDQTLYGF
CCCCCCCEEEECCCEEEEEEECCCEEEEECCCCEEEEECCCHHHHHHHHHCCCCCEEECC
KKAEDKELFLNLLKVKGIGPKSALAILANDDHTGLINAINNDDVSYLKKFPKIGPKAAQQ
CCCCCHHHHHHHHHHCCCCCCCEEEEEECCCCCEEEEECCCCCHHHHHHCCCCCHHHHHH
IILDLKGKVAVENEVGTLFDLSTTSNQALDEALEALIALGYSEKEVKKLTKKLSEQTDRT
HHHHCCCCEEEECCCCEEEEECCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCH
TDQYISSGLKLLMKG
HHHHHHHHHHHEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA