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The map label for this gene is rsmB [H]

Identifier: 116492597

GI number: 116492597

Start: 835788

End: 837122

Strand: Direct

Name: rsmB [H]

Synonym: PEPE_0830

Alternate gene names: 116492597

Gene position: 835788-837122 (Clockwise)

Preceding gene: 116492596

Following gene: 116492598

Centisome position: 45.61

GC content: 36.18

Gene sequence:

>1335_bases
ATGACAAATCAAAATAATAGTGCACGAAATTTAGCAGTTGATATTTTAGAAAAGATTGATGAAGGTTCTTTTTCCAATAT
TCAACTTAATCAAGATATAAAAAGTTCATCATTGATTGATATTGATAAAAATTTGTTAACAGAAATTGTATACGGAGTTT
TGCAACATCGACTCACTCTTGATTTTTATTTAGCTGATTATATTAGGAAACCAGAGATGACTCCGCGCTGGGTCATTAAT
CTACTAAGAACAGCTGTTTTCCAAATGGAGTTTCTAGATCGCGTACCGGACTTTGCTATTTTTAATGAATCAATTGAAAT
TGCTAAGCTTCGGGGCAATGACGGTATCAGAAAAATGGTGACGGGTGTGCTACGCTCGTATCAGAGAAATGGTAAACCAA
GTTTTGATTCGATCAAAAATCCAGTGGAAAAATTATCGACTCAATATAGCGTTGCTCCTTGGATTGTTGATCAAATGTTA
TACGAATTGGGTGAGGAAAAATGCATTTCAATTTTGAAGAGTATTAACCAACCGTCCCATCTTGCGGTTCGTATTAATCG
TTGGAATAAAACACATGCGGATATTATTAAAGATTTAGAATATGAGTATACGGTAACGACAAGTGCAATTGCTAAAGATG
GATTACGTCTTAGCAAAGGGGCTAGTATTTCTGATACAAGAAGTTATATTGATGGTGATTTGACCGTTCAAGATGAATCA
GCGATGTTAGTTGCAGAAACGATGCACTTAGAGAAGGGGCAAAAAGTGCTAGATGCTTGTGCCGCTCCCGGGGGGAAGAC
GACCCAAATAGCCGCGATGATTGGCGAAACAGGAGAAGTAACTGGATGGGATATCTATCAAAAACGAGTGCAATTAATTC
AAGATAATGCGCAAAGAATGCATCTGGAGAACGTTAAGACTGAGGTTCAGGATGCCATTGCTCCTCGTGAAGATTTAGAT
GAAAGTTTTGATCGAATTTTAGTAGATGCACCATGTTCGGGAATTGGTTTGATGAGAAGAAAACCAGAAATCCGTTATCT
TAAGAGTAAGAAGGATAGTAGCGACCTTCATCAACTCCAATTAAAAATCTTGGATAATATTGCTAAAATGCTCAAAGTAG
GTGGCGTACTAACTTATAGTACATGTACAATTTTGCGTAAAGAAAATCAAGAAACCATAGAAAAATTCCTAGCTATCCAT
CCTGAATTTGAACAACTCAAAGTTGAAACAGCTAAAAAAATCAAGCAAAATCGAGATGAATTGAGCCTTAATATTTATCC
TGATGATTTTGAATCAGACGGCTTTTTCATCGCTAATTTAAAAAAGGTGAAGTGA

Upstream 100 bases:

>100_bases
ATTGAAGAATTACAGCCAGCTGGCAAACAAAAGATGACAATTACAGACTATCTCAATGGAGTAGGTGAAAACTTACACCC
AGGAAAGCAAATAATAGATA

Downstream 100 bases:

>100_bases
TTGGTGTTATGAAATATGCGTACCTATCTGATAAAGGACAAGTTCGAGAGACTAACCAAGACTATGTAGGAATTTTCAAA
AATGATTCTGAAGCTATTTT

Product: tRNA and rRNA cytosine-C5-methylase

Products: NA

Alternate protein names: rRNA (cytosine-C(5)-)-methyltransferase rsmB [H]

Number of amino acids: Translated: 444; Mature: 443

Protein sequence:

>444_residues
MTNQNNSARNLAVDILEKIDEGSFSNIQLNQDIKSSSLIDIDKNLLTEIVYGVLQHRLTLDFYLADYIRKPEMTPRWVIN
LLRTAVFQMEFLDRVPDFAIFNESIEIAKLRGNDGIRKMVTGVLRSYQRNGKPSFDSIKNPVEKLSTQYSVAPWIVDQML
YELGEEKCISILKSINQPSHLAVRINRWNKTHADIIKDLEYEYTVTTSAIAKDGLRLSKGASISDTRSYIDGDLTVQDES
AMLVAETMHLEKGQKVLDACAAPGGKTTQIAAMIGETGEVTGWDIYQKRVQLIQDNAQRMHLENVKTEVQDAIAPREDLD
ESFDRILVDAPCSGIGLMRRKPEIRYLKSKKDSSDLHQLQLKILDNIAKMLKVGGVLTYSTCTILRKENQETIEKFLAIH
PEFEQLKVETAKKIKQNRDELSLNIYPDDFESDGFFIANLKKVK

Sequences:

>Translated_444_residues
MTNQNNSARNLAVDILEKIDEGSFSNIQLNQDIKSSSLIDIDKNLLTEIVYGVLQHRLTLDFYLADYIRKPEMTPRWVIN
LLRTAVFQMEFLDRVPDFAIFNESIEIAKLRGNDGIRKMVTGVLRSYQRNGKPSFDSIKNPVEKLSTQYSVAPWIVDQML
YELGEEKCISILKSINQPSHLAVRINRWNKTHADIIKDLEYEYTVTTSAIAKDGLRLSKGASISDTRSYIDGDLTVQDES
AMLVAETMHLEKGQKVLDACAAPGGKTTQIAAMIGETGEVTGWDIYQKRVQLIQDNAQRMHLENVKTEVQDAIAPREDLD
ESFDRILVDAPCSGIGLMRRKPEIRYLKSKKDSSDLHQLQLKILDNIAKMLKVGGVLTYSTCTILRKENQETIEKFLAIH
PEFEQLKVETAKKIKQNRDELSLNIYPDDFESDGFFIANLKKVK
>Mature_443_residues
TNQNNSARNLAVDILEKIDEGSFSNIQLNQDIKSSSLIDIDKNLLTEIVYGVLQHRLTLDFYLADYIRKPEMTPRWVINL
LRTAVFQMEFLDRVPDFAIFNESIEIAKLRGNDGIRKMVTGVLRSYQRNGKPSFDSIKNPVEKLSTQYSVAPWIVDQMLY
ELGEEKCISILKSINQPSHLAVRINRWNKTHADIIKDLEYEYTVTTSAIAKDGLRLSKGASISDTRSYIDGDLTVQDESA
MLVAETMHLEKGQKVLDACAAPGGKTTQIAAMIGETGEVTGWDIYQKRVQLIQDNAQRMHLENVKTEVQDAIAPREDLDE
SFDRILVDAPCSGIGLMRRKPEIRYLKSKKDSSDLHQLQLKILDNIAKMLKVGGVLTYSTCTILRKENQETIEKFLAIHP
EFEQLKVETAKKIKQNRDELSLNIYPDDFESDGFFIANLKKVK

Specific function: Unknown

COG id: COG0144

COG function: function code J; tRNA and rRNA cytosine-C5-methylases

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. RsmB/NOP family [H]

Homologues:

Organism=Homo sapiens, GI32698918, Length=276, Percent_Identity=32.6086956521739, Blast_Score=119, Evalue=8e-27,
Organism=Homo sapiens, GI76150625, Length=346, Percent_Identity=27.7456647398844, Blast_Score=109, Evalue=5e-24,
Organism=Homo sapiens, GI76150623, Length=346, Percent_Identity=27.7456647398844, Blast_Score=109, Evalue=5e-24,
Organism=Homo sapiens, GI39995082, Length=190, Percent_Identity=32.6315789473684, Blast_Score=91, Evalue=3e-18,
Organism=Homo sapiens, GI301336155, Length=190, Percent_Identity=32.6315789473684, Blast_Score=91, Evalue=3e-18,
Organism=Homo sapiens, GI8922322, Length=236, Percent_Identity=25.8474576271186, Blast_Score=81, Evalue=2e-15,
Organism=Homo sapiens, GI270288818, Length=236, Percent_Identity=25.8474576271186, Blast_Score=81, Evalue=2e-15,
Organism=Homo sapiens, GI23199998, Length=236, Percent_Identity=25.8474576271186, Blast_Score=81, Evalue=2e-15,
Organism=Homo sapiens, GI270288816, Length=236, Percent_Identity=25.8474576271186, Blast_Score=81, Evalue=2e-15,
Organism=Homo sapiens, GI11545785, Length=223, Percent_Identity=28.2511210762332, Blast_Score=76, Evalue=6e-14,
Organism=Escherichia coli, GI2367212, Length=450, Percent_Identity=32, Blast_Score=185, Evalue=5e-48,
Organism=Escherichia coli, GI87081985, Length=284, Percent_Identity=27.8169014084507, Blast_Score=128, Evalue=9e-31,
Organism=Caenorhabditis elegans, GI17536757, Length=392, Percent_Identity=26.7857142857143, Blast_Score=113, Evalue=2e-25,
Organism=Caenorhabditis elegans, GI25143471, Length=177, Percent_Identity=33.8983050847458, Blast_Score=91, Evalue=1e-18,
Organism=Caenorhabditis elegans, GI115534021, Length=238, Percent_Identity=27.7310924369748, Blast_Score=75, Evalue=7e-14,
Organism=Caenorhabditis elegans, GI71998419, Length=238, Percent_Identity=27.7310924369748, Blast_Score=75, Evalue=9e-14,
Organism=Saccharomyces cerevisiae, GI6324268, Length=238, Percent_Identity=31.0924369747899, Blast_Score=107, Evalue=3e-24,
Organism=Saccharomyces cerevisiae, GI6319447, Length=181, Percent_Identity=32.0441988950276, Blast_Score=85, Evalue=3e-17,
Organism=Drosophila melanogaster, GI22024126, Length=230, Percent_Identity=31.7391304347826, Blast_Score=120, Evalue=1e-27,
Organism=Drosophila melanogaster, GI24668781, Length=245, Percent_Identity=28.9795918367347, Blast_Score=95, Evalue=1e-19,
Organism=Drosophila melanogaster, GI21356513, Length=245, Percent_Identity=28.9795918367347, Blast_Score=94, Evalue=2e-19,
Organism=Drosophila melanogaster, GI21355201, Length=183, Percent_Identity=28.9617486338798, Blast_Score=86, Evalue=6e-17,
Organism=Drosophila melanogaster, GI21356579, Length=216, Percent_Identity=27.3148148148148, Blast_Score=81, Evalue=1e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001678
- InterPro:   IPR018314
- InterPro:   IPR006027
- InterPro:   IPR004573 [H]

Pfam domain/function: PF01189 Nol1_Nop2_Fmu; PF01029 NusB [H]

EC number: NA

Molecular weight: Translated: 50493; Mature: 50362

Theoretical pI: Translated: 5.99; Mature: 5.99

Prosite motif: PS01153 NOL1_NOP2_SUN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTNQNNSARNLAVDILEKIDEGSFSNIQLNQDIKSSSLIDIDKNLLTEIVYGVLQHRLTL
CCCCCCCHHHHHHHHHHHHCCCCCCCEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
DFYLADYIRKPEMTPRWVINLLRTAVFQMEFLDRVPDFAIFNESIEIAKLRGNDGIRKMV
HHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEECCCEEEEEECCCCCHHHHH
TGVLRSYQRNGKPSFDSIKNPVEKLSTQYSVAPWIVDQMLYELGEEKCISILKSINQPSH
HHHHHHHHHCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCHHHHHHHHHHCCCCCE
LAVRINRWNKTHADIIKDLEYEYTVTTSAIAKDGLRLSKGASISDTRSYIDGDLTVQDES
EEEEEECCCCHHHHHHHHCCCEEEEEHHHHHHCCCCCCCCCCCCHHHHHCCCCEEEECCC
AMLVAETMHLEKGQKVLDACAAPGGKTTQIAAMIGETGEVTGWDIYQKRVQLIQDNAQRM
CCHHHHHHHHHHHHHHHHHHCCCCCCCEEHHEECCCCCCCCCHHHHHHHHHHHHHHHHHH
HLENVKTEVQDAIAPREDLDESFDRILVDAPCSGIGLMRRKPEIRYLKSKKDSSDLHQLQ
HHHHHHHHHHHHCCCHHHHHHHHHHEEEECCCCCCHHHHCCCHHHHHHCCCCCHHHHHHH
LKILDNIAKMLKVGGVLTYSTCTILRKENQETIEKFLAIHPEFEQLKVETAKKIKQNRDE
HHHHHHHHHHHHHCCEEEEHHHHHHHHCCHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCC
LSLNIYPDDFESDGFFIANLKKVK
EEEEECCCCCCCCCEEEEEEEECC
>Mature Secondary Structure 
TNQNNSARNLAVDILEKIDEGSFSNIQLNQDIKSSSLIDIDKNLLTEIVYGVLQHRLTL
CCCCCCHHHHHHHHHHHHCCCCCCCEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
DFYLADYIRKPEMTPRWVINLLRTAVFQMEFLDRVPDFAIFNESIEIAKLRGNDGIRKMV
HHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEECCCEEEEEECCCCCHHHHH
TGVLRSYQRNGKPSFDSIKNPVEKLSTQYSVAPWIVDQMLYELGEEKCISILKSINQPSH
HHHHHHHHHCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCHHHHHHHHHHCCCCCE
LAVRINRWNKTHADIIKDLEYEYTVTTSAIAKDGLRLSKGASISDTRSYIDGDLTVQDES
EEEEEECCCCHHHHHHHHCCCEEEEEHHHHHHCCCCCCCCCCCCHHHHHCCCCEEEECCC
AMLVAETMHLEKGQKVLDACAAPGGKTTQIAAMIGETGEVTGWDIYQKRVQLIQDNAQRM
CCHHHHHHHHHHHHHHHHHHCCCCCCCEEHHEECCCCCCCCCHHHHHHHHHHHHHHHHHH
HLENVKTEVQDAIAPREDLDESFDRILVDAPCSGIGLMRRKPEIRYLKSKKDSSDLHQLQ
HHHHHHHHHHHHCCCHHHHHHHHHHEEEECCCCCCHHHHCCCHHHHHHCCCCCHHHHHHH
LKILDNIAKMLKVGGVLTYSTCTILRKENQETIEKFLAIHPEFEQLKVETAKKIKQNRDE
HHHHHHHHHHHHHCCEEEEHHHHHHHHCCHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCC
LSLNIYPDDFESDGFFIANLKKVK
EEEEECCCCCCCCCEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9534248; 9384377; 9086272 [H]