Click here to switch to the map view.

The map label for this gene is prpC [H]

Identifier: 116492598

GI number: 116492598

Start: 837131

End: 837877

Strand: Direct

Name: prpC [H]

Synonym: PEPE_0831

Alternate gene names: 116492598

Gene position: 837131-837877 (Clockwise)

Preceding gene: 116492597

Following gene: 116492599

Centisome position: 45.69

GC content: 35.88

Gene sequence:

>747_bases
ATGAAATATGCGTACCTATCTGATAAAGGACAAGTTCGAGAGACTAACCAAGACTATGTAGGAATTTTCAAAAATGATTC
TGAAGCTATTTTAACCATTGTAGCTGACGGTGTGGGTGGCAATCGGGGCGGCGATGTAGCTTCCGAGATGGCCGTTTCAC
ACATTGGGTATCTATTTGAAACTTCTGACGTTAATAATGTTACTGATGCTAAAAATTGGTTAATACGCCAACTTGCTCTT
GAAAATCGTAAAATTTTGCAAGCATCTAAGCACTATAAAAAATTAAATGGCATGGGAACAACCATCGTTTTGGCACTCTT
TTTAGGTAAGCAAGTGATTGTAGCTAATCTTGGCGACAGTCGTTGCTATTTATATAGTTCGAAAAATGGTTTGAAACAAC
TATCGACCGATCACTCCTTAGTGAATGAACTACTTCGTTTAGGAAAAATTACTCCTGAAGAAGCTCGTAACCATCCAGAA
AAAAATGTAATTACTAAAACTTTAGGAATTTCAGAACAAGCCGAAGCTGAGATTAAAGTATTTGATATTACCAAAGAAGA
TGAATTGCTACTTTGCACGGACGGATTAACTAAATTTGTTTCTGATGATATGATCAAAAATGTGTTGATGAGTACGCTTA
GCCTTGAAAAAAAAGCTAATCAGTTAGTAGATATGGCTAACACTGCAGGTGGAACAGATAATATTACAACTTTAATTGTT
CAAGTAGAAGAGGGGGATATATTATGA

Upstream 100 bases:

>100_bases
AGCAAAATCGAGATGAATTGAGCCTTAATATTTATCCTGATGATTTTGAATCAGACGGCTTTTTCATCGCTAATTTAAAA
AAGGTGAAGTGATTGGTGTT

Downstream 100 bases:

>100_bases
CCCCTAACCAAACTTTGAATGGTCGATATAAAATTATTCGACCACTTGGAGAAGGCGGAATGGCTAATGTTTATCTGGCA
CATGATTTAATTTTAGATCG

Product: Serine/threonine protein phosphatase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 248; Mature: 248

Protein sequence:

>248_residues
MKYAYLSDKGQVRETNQDYVGIFKNDSEAILTIVADGVGGNRGGDVASEMAVSHIGYLFETSDVNNVTDAKNWLIRQLAL
ENRKILQASKHYKKLNGMGTTIVLALFLGKQVIVANLGDSRCYLYSSKNGLKQLSTDHSLVNELLRLGKITPEEARNHPE
KNVITKTLGISEQAEAEIKVFDITKEDELLLCTDGLTKFVSDDMIKNVLMSTLSLEKKANQLVDMANTAGGTDNITTLIV
QVEEGDIL

Sequences:

>Translated_248_residues
MKYAYLSDKGQVRETNQDYVGIFKNDSEAILTIVADGVGGNRGGDVASEMAVSHIGYLFETSDVNNVTDAKNWLIRQLAL
ENRKILQASKHYKKLNGMGTTIVLALFLGKQVIVANLGDSRCYLYSSKNGLKQLSTDHSLVNELLRLGKITPEEARNHPE
KNVITKTLGISEQAEAEIKVFDITKEDELLLCTDGLTKFVSDDMIKNVLMSTLSLEKKANQLVDMANTAGGTDNITTLIV
QVEEGDIL
>Mature_248_residues
MKYAYLSDKGQVRETNQDYVGIFKNDSEAILTIVADGVGGNRGGDVASEMAVSHIGYLFETSDVNNVTDAKNWLIRQLAL
ENRKILQASKHYKKLNGMGTTIVLALFLGKQVIVANLGDSRCYLYSSKNGLKQLSTDHSLVNELLRLGKITPEEARNHPE
KNVITKTLGISEQAEAEIKVFDITKEDELLLCTDGLTKFVSDDMIKNVLMSTLSLEKKANQLVDMANTAGGTDNITTLIV
QVEEGDIL

Specific function: Protein phosphatase that dephosphorylates prkC and fusA (elongation factor G). PrpC and prkC are cotranscribed, which suggests that they form a functional couple in vivo, prpC's primary role being possibly to counter the action of prkC. May be involved in

COG id: COG0631

COG function: function code T; Serine/threonine protein phosphatase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PP2C-like domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015655
- InterPro:   IPR001932
- InterPro:   IPR014045 [H]

Pfam domain/function: PF00481 PP2C [H]

EC number: =3.1.3.16 [H]

Molecular weight: Translated: 27269; Mature: 27269

Theoretical pI: Translated: 5.01; Mature: 5.01

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKYAYLSDKGQVRETNQDYVGIFKNDSEAILTIVADGVGGNRGGDVASEMAVSHIGYLFE
CCEEEECCCCCCCCCCCCEEEEEECCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHEEE
TSDVNNVTDAKNWLIRQLALENRKILQASKHYKKLNGMGTTIVLALFLGKQVIVANLGDS
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCEEEEEECCCC
RCYLYSSKNGLKQLSTDHSLVNELLRLGKITPEEARNHPEKNVITKTLGISEQAEAEIKV
EEEEEECCCCHHHHCCHHHHHHHHHHHCCCCHHHHHCCCCHHHHHHHCCCCCCCCCEEEE
FDITKEDELLLCTDGLTKFVSDDMIKNVLMSTLSLEKKANQLVDMANTAGGTDNITTLIV
EEECCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEE
QVEEGDIL
EECCCCCC
>Mature Secondary Structure
MKYAYLSDKGQVRETNQDYVGIFKNDSEAILTIVADGVGGNRGGDVASEMAVSHIGYLFE
CCEEEECCCCCCCCCCCCEEEEEECCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHEEE
TSDVNNVTDAKNWLIRQLALENRKILQASKHYKKLNGMGTTIVLALFLGKQVIVANLGDS
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCEEEEEECCCC
RCYLYSSKNGLKQLSTDHSLVNELLRLGKITPEEARNHPEKNVITKTLGISEQAEAEIKV
EEEEEECCCCHHHHCCHHHHHHHHHHHCCCCHHHHHCCCCHHHHHHHCCCCCCCCCEEEE
FDITKEDELLLCTDGLTKFVSDDMIKNVLMSTLSLEKKANQLVDMANTAGGTDNITTLIV
EEECCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEE
QVEEGDIL
EECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9534248; 9384377 [H]