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The map label for this gene is xylB [H]

Identifier: 116491999

GI number: 116491999

Start: 222180

End: 223685

Strand: Direct

Name: xylB [H]

Synonym: PEPE_0188

Alternate gene names: 116491999

Gene position: 222180-223685 (Clockwise)

Preceding gene: 116491998

Following gene: 116492000

Centisome position: 12.13

GC content: 41.7

Gene sequence:

>1506_bases
ATGGAAGTTGTATTAGGAGTGGATTTGGGAACAAGTGCGGTTAAGGTATCGGCTGTCGATCGTGAAGGGAAAATTGTTGC
CCAACAAAGTGAAGCTTACAGTTTGAATCAGCCCGAACCAGGTTATAGTGAACAAAATCCGGAGGATTGGGTAACCGGAA
CAACTGCGGCTATCGACCGGTTGATTAAAGTGGATGGTATCAAACCGGATGAAATTACTGGGATTAGCTATTCTGGACAA
ATGCATGGACTGGTTCTATTAGATGATCATAATCAAGTTTTACGCCCAGCTATTTTGTGGAATGATACCCGAACAACGGA
ACAATGCAAAGAAATTCTAGATACAATGGGACAAGATTTTATTGATATCACTCGTAATGTTCCACTAGAAGGATTTACTT
TGCCTAAACTTTTATGGGTAAAAGAAAATGAACCAGAACTCTTTAATAATGTATCAGTATTCTTATTGCCCAAGGATTAT
CTAAGATATCGGATGACCGGGAAAATCGCGATGGAATATTCGGACGCGGCAGGAACCGTAATGTTAGATGAAGAAAACAA
AACTTGGAGTACGAAGATTGCGGACGCCTTCGACTTGTCTCAAACAATCTTCCCGCCATTAATTGAATCCATTGGATTCG
CTGGTACGATTGGAGATACGTATGCGAAGTTCTCCGGATTGAAGACGACGACTAAGATCTACGGCGGAGCCGCTGATAAT
GCGGCAGGAGCGATTGGAGCCGGAATCTTAAGTTCTAATCAAGTCCTATCTTCAATTGGAACTTCCGGAGTAGTATTGAA
GTATGAAGATAATGCCGATGTCGATTATAAGGGAGCATTACATTTCTTTAACCACGCTATTCCAAATAAATTTTATACGA
TGGGAGTGACCTTAGCGGCGGGCTACAGTTTGAGTTGGTTTAAGAAGACTTTTAGTGCCGATCAAGATTTCACAGAATTT
GTAAACGCCGCAGGCGATTCCACCGTTGGTGCTAATGGTTTGTTATTTACGCCATATATTGTTGGCGAACGGACTCCATA
CCCTGATGGTGACGCGCGCGGTAGTTTCATTGGAATTGATGGAACCCATAATAAGGCAGACTTTACTCGGGCTGTATTAG
AGGGAATTGTCTTCTCGTTCAAAGATATTATGCGAATCTTTGCCGAAAAAGGTAGTAATTTTGATACGGTAGTATCAATC
GGAGGAGGCGCTAAGAGTCCACTATGGCTCCAAATTCAAGCCGATGTTTTCAATAAGAAAGTAGTTACGTTGAAAAACGA
ACAAGGCCCCGGCTTGGGAGCGGCAATGATTGCCGCTGTAGGAGTCGGTTGGTTCGATTCATTGAGCGATTGTGCCCAAA
AGTTTGTGTCATATGATCAAGAATATGTGCCTGGTAGTGGTAATGTCGAAAAGTATGAAAAGATGTATCAATTGTATAAA
CAAGTGTATGGACAAACCGCAGAAATCAGTCATAAATTAATGGAATATAGACGAAATAATCTCTAG

Upstream 100 bases:

>100_bases
CAATTGAAATCAACATTAAATAATTATATTTTTACCGTATTAGGCAAATAAGCGAAAAGGTGGCGAATTGCCACCTTTTT
ATTTTGAAGAGGTGAATGAC

Downstream 100 bases:

>100_bases
AGATTATTTATAGAGGCTTTCTCCAAATTAGTGGAGAAGGCTTTTTTATGTGAAATGAAACATGTTTCATGAAATGACAC
GTGTTACATAGGTTAGAACC

Product: xylulokinase

Products: NA

Alternate protein names: Xylulokinase [H]

Number of amino acids: Translated: 501; Mature: 501

Protein sequence:

>501_residues
MEVVLGVDLGTSAVKVSAVDREGKIVAQQSEAYSLNQPEPGYSEQNPEDWVTGTTAAIDRLIKVDGIKPDEITGISYSGQ
MHGLVLLDDHNQVLRPAILWNDTRTTEQCKEILDTMGQDFIDITRNVPLEGFTLPKLLWVKENEPELFNNVSVFLLPKDY
LRYRMTGKIAMEYSDAAGTVMLDEENKTWSTKIADAFDLSQTIFPPLIESIGFAGTIGDTYAKFSGLKTTTKIYGGAADN
AAGAIGAGILSSNQVLSSIGTSGVVLKYEDNADVDYKGALHFFNHAIPNKFYTMGVTLAAGYSLSWFKKTFSADQDFTEF
VNAAGDSTVGANGLLFTPYIVGERTPYPDGDARGSFIGIDGTHNKADFTRAVLEGIVFSFKDIMRIFAEKGSNFDTVVSI
GGGAKSPLWLQIQADVFNKKVVTLKNEQGPGLGAAMIAAVGVGWFDSLSDCAQKFVSYDQEYVPGSGNVEKYEKMYQLYK
QVYGQTAEISHKLMEYRRNNL

Sequences:

>Translated_501_residues
MEVVLGVDLGTSAVKVSAVDREGKIVAQQSEAYSLNQPEPGYSEQNPEDWVTGTTAAIDRLIKVDGIKPDEITGISYSGQ
MHGLVLLDDHNQVLRPAILWNDTRTTEQCKEILDTMGQDFIDITRNVPLEGFTLPKLLWVKENEPELFNNVSVFLLPKDY
LRYRMTGKIAMEYSDAAGTVMLDEENKTWSTKIADAFDLSQTIFPPLIESIGFAGTIGDTYAKFSGLKTTTKIYGGAADN
AAGAIGAGILSSNQVLSSIGTSGVVLKYEDNADVDYKGALHFFNHAIPNKFYTMGVTLAAGYSLSWFKKTFSADQDFTEF
VNAAGDSTVGANGLLFTPYIVGERTPYPDGDARGSFIGIDGTHNKADFTRAVLEGIVFSFKDIMRIFAEKGSNFDTVVSI
GGGAKSPLWLQIQADVFNKKVVTLKNEQGPGLGAAMIAAVGVGWFDSLSDCAQKFVSYDQEYVPGSGNVEKYEKMYQLYK
QVYGQTAEISHKLMEYRRNNL
>Mature_501_residues
MEVVLGVDLGTSAVKVSAVDREGKIVAQQSEAYSLNQPEPGYSEQNPEDWVTGTTAAIDRLIKVDGIKPDEITGISYSGQ
MHGLVLLDDHNQVLRPAILWNDTRTTEQCKEILDTMGQDFIDITRNVPLEGFTLPKLLWVKENEPELFNNVSVFLLPKDY
LRYRMTGKIAMEYSDAAGTVMLDEENKTWSTKIADAFDLSQTIFPPLIESIGFAGTIGDTYAKFSGLKTTTKIYGGAADN
AAGAIGAGILSSNQVLSSIGTSGVVLKYEDNADVDYKGALHFFNHAIPNKFYTMGVTLAAGYSLSWFKKTFSADQDFTEF
VNAAGDSTVGANGLLFTPYIVGERTPYPDGDARGSFIGIDGTHNKADFTRAVLEGIVFSFKDIMRIFAEKGSNFDTVVSI
GGGAKSPLWLQIQADVFNKKVVTLKNEQGPGLGAAMIAAVGVGWFDSLSDCAQKFVSYDQEYVPGSGNVEKYEKMYQLYK
QVYGQTAEISHKLMEYRRNNL

Specific function: Unknown

COG id: COG1070

COG function: function code G; Sugar (pentulose and hexulose) kinases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FGGY kinase family [H]

Homologues:

Organism=Homo sapiens, GI18860918, Length=488, Percent_Identity=23.155737704918, Blast_Score=91, Evalue=3e-18,
Organism=Homo sapiens, GI42794763, Length=444, Percent_Identity=21.3963963963964, Blast_Score=82, Evalue=1e-15,
Organism=Homo sapiens, GI41393575, Length=410, Percent_Identity=21.4634146341463, Blast_Score=80, Evalue=4e-15,
Organism=Homo sapiens, GI189409120, Length=444, Percent_Identity=21.3963963963964, Blast_Score=77, Evalue=4e-14,
Organism=Homo sapiens, GI4504007, Length=444, Percent_Identity=21.3963963963964, Blast_Score=77, Evalue=4e-14,
Organism=Escherichia coli, GI1789987, Length=482, Percent_Identity=36.7219917012448, Blast_Score=308, Evalue=8e-85,
Organism=Escherichia coli, GI1790005, Length=499, Percent_Identity=25.6513026052104, Blast_Score=176, Evalue=3e-45,
Organism=Escherichia coli, GI1787789, Length=515, Percent_Identity=23.6893203883495, Blast_Score=135, Evalue=5e-33,
Organism=Escherichia coli, GI1789168, Length=470, Percent_Identity=25.7446808510638, Blast_Score=127, Evalue=1e-30,
Organism=Escherichia coli, GI1790361, Length=499, Percent_Identity=23.6472945891784, Blast_Score=125, Evalue=7e-30,
Organism=Escherichia coli, GI1789138, Length=516, Percent_Identity=23.062015503876, Blast_Score=92, Evalue=6e-20,
Organism=Caenorhabditis elegans, GI17535599, Length=448, Percent_Identity=24.7767857142857, Blast_Score=107, Evalue=2e-23,
Organism=Drosophila melanogaster, GI17864214, Length=464, Percent_Identity=27.1551724137931, Blast_Score=123, Evalue=2e-28,
Organism=Drosophila melanogaster, GI24654573, Length=408, Percent_Identity=27.2058823529412, Blast_Score=117, Evalue=2e-26,
Organism=Drosophila melanogaster, GI24657106, Length=527, Percent_Identity=24.6679316888046, Blast_Score=111, Evalue=1e-24,
Organism=Drosophila melanogaster, GI24657102, Length=527, Percent_Identity=24.6679316888046, Blast_Score=111, Evalue=1e-24,
Organism=Drosophila melanogaster, GI24655555, Length=501, Percent_Identity=21.7564870259481, Blast_Score=91, Evalue=2e-18,
Organism=Drosophila melanogaster, GI24655560, Length=501, Percent_Identity=21.7564870259481, Blast_Score=91, Evalue=2e-18,
Organism=Drosophila melanogaster, GI24655570, Length=501, Percent_Identity=21.7564870259481, Blast_Score=91, Evalue=2e-18,
Organism=Drosophila melanogaster, GI24655574, Length=501, Percent_Identity=21.7564870259481, Blast_Score=91, Evalue=2e-18,
Organism=Drosophila melanogaster, GI24655565, Length=501, Percent_Identity=21.7564870259481, Blast_Score=91, Evalue=2e-18,
Organism=Drosophila melanogaster, GI19920476, Length=497, Percent_Identity=25.3521126760563, Blast_Score=89, Evalue=6e-18,
Organism=Drosophila melanogaster, GI24656367, Length=514, Percent_Identity=20.8171206225681, Blast_Score=86, Evalue=7e-17,
Organism=Drosophila melanogaster, GI21356607, Length=488, Percent_Identity=22.7459016393443, Blast_Score=70, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000577
- InterPro:   IPR018485
- InterPro:   IPR018483
- InterPro:   IPR018484
- InterPro:   IPR006000 [H]

Pfam domain/function: PF02782 FGGY_C; PF00370 FGGY_N [H]

EC number: =2.7.1.17 [H]

Molecular weight: Translated: 54820; Mature: 54820

Theoretical pI: Translated: 4.58; Mature: 4.58

Prosite motif: PS00933 FGGY_KINASES_1 ; PS00445 FGGY_KINASES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEVVLGVDLGTSAVKVSAVDREGKIVAQQSEAYSLNQPEPGYSEQNPEDWVTGTTAAIDR
CEEEEEECCCCCEEEEEEECCCCCEEEECCCCCCCCCCCCCCCCCCCHHHHCCCHHHHHH
LIKVDGIKPDEITGISYSGQMHGLVLLDDHNQVLRPAILWNDTRTTEQCKEILDTMGQDF
HHHHCCCCCCCCCCEEECCCEEEEEEECCCCCHHCCEEEECCCCCHHHHHHHHHHHCCHH
IDITRNVPLEGFTLPKLLWVKENEPELFNNVSVFLLPKDYLRYRMTGKIAMEYSDAAGTV
HHHHCCCCCCCCCCCEEEEEECCCCHHHCCCEEEEECHHHHHEEECCEEEEEECCCCCEE
MLDEENKTWSTKIADAFDLSQTIFPPLIESIGFAGTIGDTYAKFSGLKTTTKIYGGAADN
EECCCCCEEHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHCCCCEEHEEECCCCCC
AAGAIGAGILSSNQVLSSIGTSGVVLKYEDNADVDYKGALHFFNHAIPNKFYTMGVTLAA
CCCHHHHHHHCCHHHHHHCCCCCEEEEECCCCCCCCCHHHHHHHHHCCCCEEEEEEEEEC
GYSLSWFKKTFSADQDFTEFVNAAGDSTVGANGLLFTPYIVGERTPYPDGDARGSFIGID
CCCHHHHHHHHCCCHHHHHHHHCCCCCCCCCCCEEEEEEEECCCCCCCCCCCCCCEEEEC
GTHNKADFTRAVLEGIVFSFKDIMRIFAEKGSNFDTVVSIGGGAKSPLWLQIQADVFNKK
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCEEEEEEECCCCCE
VVTLKNEQGPGLGAAMIAAVGVGWFDSLSDCAQKFVSYDQEYVPGSGNVEKYEKMYQLYK
EEEEECCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHCCCHHCCCCCCCHHHHHHHHHHHH
QVYGQTAEISHKLMEYRRNNL
HHCCCHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MEVVLGVDLGTSAVKVSAVDREGKIVAQQSEAYSLNQPEPGYSEQNPEDWVTGTTAAIDR
CEEEEEECCCCCEEEEEEECCCCCEEEECCCCCCCCCCCCCCCCCCCHHHHCCCHHHHHH
LIKVDGIKPDEITGISYSGQMHGLVLLDDHNQVLRPAILWNDTRTTEQCKEILDTMGQDF
HHHHCCCCCCCCCCEEECCCEEEEEEECCCCCHHCCEEEECCCCCHHHHHHHHHHHCCHH
IDITRNVPLEGFTLPKLLWVKENEPELFNNVSVFLLPKDYLRYRMTGKIAMEYSDAAGTV
HHHHCCCCCCCCCCCEEEEEECCCCHHHCCCEEEEECHHHHHEEECCEEEEEECCCCCEE
MLDEENKTWSTKIADAFDLSQTIFPPLIESIGFAGTIGDTYAKFSGLKTTTKIYGGAADN
EECCCCCEEHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHCCCCEEHEEECCCCCC
AAGAIGAGILSSNQVLSSIGTSGVVLKYEDNADVDYKGALHFFNHAIPNKFYTMGVTLAA
CCCHHHHHHHCCHHHHHHCCCCCEEEEECCCCCCCCCHHHHHHHHHCCCCEEEEEEEEEC
GYSLSWFKKTFSADQDFTEFVNAAGDSTVGANGLLFTPYIVGERTPYPDGDARGSFIGID
CCCHHHHHHHHCCCHHHHHHHHCCCCCCCCCCCEEEEEEEECCCCCCCCCCCCCCEEEEC
GTHNKADFTRAVLEGIVFSFKDIMRIFAEKGSNFDTVVSIGGGAKSPLWLQIQADVFNKK
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCEEEEEEECCCCCE
VVTLKNEQGPGLGAAMIAAVGVGWFDSLSDCAQKFVSYDQEYVPGSGNVEKYEKMYQLYK
EEEEECCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHCCCHHCCCCCCCHHHHHHHHHHHH
QVYGQTAEISHKLMEYRRNNL
HHCCCHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9835554; 1587475 [H]