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The map label for this gene is xylA

Identifier: 116491998

GI number: 116491998

Start: 220787

End: 222130

Strand: Direct

Name: xylA

Synonym: PEPE_0187

Alternate gene names: 116491998

Gene position: 220787-222130 (Clockwise)

Preceding gene: 116491997

Following gene: 116491999

Centisome position: 12.05

GC content: 38.91

Gene sequence:

>1344_bases
ATGAGTGAATATTACGATTTTAACAAGATGGAATATATTGGTAACCAAAAAGGTCTAAAGGCTGGAGATGGTTTTCACTA
CTACAACCCAGACGAACTTATCCAAGGCAAGAAGATGAGCGAATGGTTGAAATTCTCCGTTGCTTACTGGCACACCATGG
ATCAACGCTTGGTTGACCCATTCGGAGATGGTACAGCTCAACGTCCATGGGACAAATTCGAAGATCCGATGGAACAAGCT
TTAGCTAAAGTAGATTACATGTTCGAATTTTTGGACAAAATGAACGTTGAATATTTCGCATTCCATGATCGTGATTTAGC
TCCAGAAGGCAATACTTTACGTGAAACTAATGCTAATTTAGACAAAGTAGTCGACAAAATTGTTGAAAAGATGCAAGAAA
CTGGTAAGAAAGTGCTTTGGAACACATCAAGCCTCTTTACTAACCCTCGTTTCGTTGCGGGTGGTGCTACAGCACCTTTT
GCTGATATCGTTGCTTACTCAGCTGCTCAAATCAAACATTCTTTGGAAATTGCTAAACGGGTAAATTCCATGAACTATGT
TTTCTGGGGTGGTCGTGAAGGTTACGAATCATTACTCAATACTGATATGAAACTTGAACAAGAACACATTGCTAAATTTT
TCCACATGGCTAAGGATTATGCTAACGAAATTGGTTACACAGGACAATTCTTGCTTGAACCAAAACCAAAGGAACCAACA
TCACATCAGTATGATACTGATGCGGCAACAACAATTGCCTTCCTTAAGACCTACGGTCTAGAAAAAGACTTTAAGTTAAA
TCTTGAAGGTAACCATGCTTATCTTGCAGGCCACACTTACGAACATGAAGTTCGCGTCGCTCGTGACGCTGGCTTACTTG
GTTCACTTGATGCCAACATGGGTGACAAGTTGATTGGTTGGGATATTGATGAATTCCCTAATGATATTTATGAAGCAACC
CTTGTTATGTATGAGATGCTTAAGAATGGTGGCCTAGCTACAGGTGGTTTAAACTTTGATGCTAAACCAAGACGTCAATC
ATTCACTATGGAAGACCTCTTCTTAGCTCATACTGCAGGTATGGACACTTATGCTGCTGGATTGAGAGTAGCTGCTAAAT
TACTTGAAGATCGTGTATTTGATTCAGTAATTGAAGATCGCTACAGCTCATTCAAATCTGGTATCGGTGCTGACTTTGAA
AATGATAAGGTAACCTTCAAAGAACTTGAAGATTATGTGATCGATAAGCCTCAATCAGAATTGATTGCCGCAACAAAATC
TGGTCACTTAGAACAATTGAAATCAACATTAAATAATTATATTTTTACCGTATTAGGCAAATAA

Upstream 100 bases:

>100_bases
AAAATGCAAGTCTTTATGGCGGCTGTGCCCAAATGATTCGAACTATTTTAGGTGTTTCGAAACTTAAATTACAATACAAA
AAATAGAAGAGGTTTTTATA

Downstream 100 bases:

>100_bases
GCGAAAAGGTGGCGAATTGCCACCTTTTTATTTTGAAGAGGTGAATGACATGGAAGTTGTATTAGGAGTGGATTTGGGAA
CAAGTGCGGTTAAGGTATCG

Product: xylose isomerase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 447; Mature: 446

Protein sequence:

>447_residues
MSEYYDFNKMEYIGNQKGLKAGDGFHYYNPDELIQGKKMSEWLKFSVAYWHTMDQRLVDPFGDGTAQRPWDKFEDPMEQA
LAKVDYMFEFLDKMNVEYFAFHDRDLAPEGNTLRETNANLDKVVDKIVEKMQETGKKVLWNTSSLFTNPRFVAGGATAPF
ADIVAYSAAQIKHSLEIAKRVNSMNYVFWGGREGYESLLNTDMKLEQEHIAKFFHMAKDYANEIGYTGQFLLEPKPKEPT
SHQYDTDAATTIAFLKTYGLEKDFKLNLEGNHAYLAGHTYEHEVRVARDAGLLGSLDANMGDKLIGWDIDEFPNDIYEAT
LVMYEMLKNGGLATGGLNFDAKPRRQSFTMEDLFLAHTAGMDTYAAGLRVAAKLLEDRVFDSVIEDRYSSFKSGIGADFE
NDKVTFKELEDYVIDKPQSELIAATKSGHLEQLKSTLNNYIFTVLGK

Sequences:

>Translated_447_residues
MSEYYDFNKMEYIGNQKGLKAGDGFHYYNPDELIQGKKMSEWLKFSVAYWHTMDQRLVDPFGDGTAQRPWDKFEDPMEQA
LAKVDYMFEFLDKMNVEYFAFHDRDLAPEGNTLRETNANLDKVVDKIVEKMQETGKKVLWNTSSLFTNPRFVAGGATAPF
ADIVAYSAAQIKHSLEIAKRVNSMNYVFWGGREGYESLLNTDMKLEQEHIAKFFHMAKDYANEIGYTGQFLLEPKPKEPT
SHQYDTDAATTIAFLKTYGLEKDFKLNLEGNHAYLAGHTYEHEVRVARDAGLLGSLDANMGDKLIGWDIDEFPNDIYEAT
LVMYEMLKNGGLATGGLNFDAKPRRQSFTMEDLFLAHTAGMDTYAAGLRVAAKLLEDRVFDSVIEDRYSSFKSGIGADFE
NDKVTFKELEDYVIDKPQSELIAATKSGHLEQLKSTLNNYIFTVLGK
>Mature_446_residues
SEYYDFNKMEYIGNQKGLKAGDGFHYYNPDELIQGKKMSEWLKFSVAYWHTMDQRLVDPFGDGTAQRPWDKFEDPMEQAL
AKVDYMFEFLDKMNVEYFAFHDRDLAPEGNTLRETNANLDKVVDKIVEKMQETGKKVLWNTSSLFTNPRFVAGGATAPFA
DIVAYSAAQIKHSLEIAKRVNSMNYVFWGGREGYESLLNTDMKLEQEHIAKFFHMAKDYANEIGYTGQFLLEPKPKEPTS
HQYDTDAATTIAFLKTYGLEKDFKLNLEGNHAYLAGHTYEHEVRVARDAGLLGSLDANMGDKLIGWDIDEFPNDIYEATL
VMYEMLKNGGLATGGLNFDAKPRRQSFTMEDLFLAHTAGMDTYAAGLRVAAKLLEDRVFDSVIEDRYSSFKSGIGADFEN
DKVTFKELEDYVIDKPQSELIAATKSGHLEQLKSTLNNYIFTVLGK

Specific function: Unknown

COG id: COG2115

COG function: function code G; Xylose isomerase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the xylose isomerase family

Homologues:

Organism=Escherichia coli, GI1789988, Length=443, Percent_Identity=44.920993227991, Blast_Score=414, Evalue=1e-117,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): XYLA_PEDPA (Q03HN1)

Other databases:

- EMBL:   CP000422
- RefSeq:   YP_803733.1
- ProteinModelPortal:   Q03HN1
- SMR:   Q03HN1
- STRING:   Q03HN1
- GeneID:   4418631
- GenomeReviews:   CP000422_GR
- KEGG:   ppe:PEPE_0187
- NMPDR:   fig|278197.10.peg.171
- eggNOG:   COG2115
- HOGENOM:   HBG297199
- OMA:   LLGWDTD
- PhylomeDB:   Q03HN1
- ProtClustDB:   PRK05474
- BioCyc:   PPEN278197:PEPE_0187-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00455
- InterPro:   IPR013022
- InterPro:   IPR012307
- InterPro:   IPR013452
- InterPro:   IPR001998
- Gene3D:   G3DSA:3.20.20.150
- PRINTS:   PR00688
- TIGRFAMs:   TIGR02630

Pfam domain/function: PF01261 AP_endonuc_2; SSF51658 Xyl_isomerase-like_TIM-brl

EC number: =5.3.1.5

Molecular weight: Translated: 50863; Mature: 50732

Theoretical pI: Translated: 4.78; Mature: 4.78

Prosite motif: PS51415 XYLOSE_ISOMERASE; PS00172 XYLOSE_ISOMERASE_1 ; PS00173 XYLOSE_ISOMERASE_2

Important sites: ACT_SITE 102-102 ACT_SITE 105-105

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEYYDFNKMEYIGNQKGLKAGDGFHYYNPDELIQGKKMSEWLKFSVAYWHTMDQRLVDP
CCCCCCCCHHHHHCCCCCCCCCCCCCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCC
FGDGTAQRPWDKFEDPMEQALAKVDYMFEFLDKMNVEYFAFHDRDLAPEGNTLRETNANL
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCHHCCCCH
DKVVDKIVEKMQETGKKVLWNTSSLFTNPRFVAGGATAPFADIVAYSAAQIKHSLEIAKR
HHHHHHHHHHHHHCCHHEEECCHHHCCCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHH
VNSMNYVFWGGREGYESLLNTDMKLEQEHIAKFFHMAKDYANEIGYTGQFLLEPKPKEPT
HCCCCEEEECCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCC
SHQYDTDAATTIAFLKTYGLEKDFKLNLEGNHAYLAGHTYEHEVRVARDAGLLGSLDANM
CCCCCCHHHHHHHHHHHHCCCCCEEEEECCCEEEEECCCCHHHHHHHHCCCCEECCCCCC
GDKLIGWDIDEFPNDIYEATLVMYEMLKNGGLATGGLNFDAKPRRQSFTMEDLFLAHTAG
CCCEECCCHHHCCHHHHHHHHHHHHHHHCCCCEECCCCCCCCCCHHCCCHHHHHHHHHCC
MDTYAAGLRVAAKLLEDRVFDSVIEDRYSSFKSGIGADFENDKVTFKELEDYVIDKPQSE
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCCCHHH
LIAATKSGHLEQLKSTLNNYIFTVLGK
HHHHHCCCHHHHHHHHHHHEEEEEECC
>Mature Secondary Structure 
SEYYDFNKMEYIGNQKGLKAGDGFHYYNPDELIQGKKMSEWLKFSVAYWHTMDQRLVDP
CCCCCCCHHHHHCCCCCCCCCCCCCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCC
FGDGTAQRPWDKFEDPMEQALAKVDYMFEFLDKMNVEYFAFHDRDLAPEGNTLRETNANL
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCHHCCCCH
DKVVDKIVEKMQETGKKVLWNTSSLFTNPRFVAGGATAPFADIVAYSAAQIKHSLEIAKR
HHHHHHHHHHHHHCCHHEEECCHHHCCCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHHH
VNSMNYVFWGGREGYESLLNTDMKLEQEHIAKFFHMAKDYANEIGYTGQFLLEPKPKEPT
HCCCCEEEECCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCC
SHQYDTDAATTIAFLKTYGLEKDFKLNLEGNHAYLAGHTYEHEVRVARDAGLLGSLDANM
CCCCCCHHHHHHHHHHHHCCCCCEEEEECCCEEEEECCCCHHHHHHHHCCCCEECCCCCC
GDKLIGWDIDEFPNDIYEATLVMYEMLKNGGLATGGLNFDAKPRRQSFTMEDLFLAHTAG
CCCEECCCHHHCCHHHHHHHHHHHHHHHCCCCEECCCCCCCCCCHHCCCHHHHHHHHHCC
MDTYAAGLRVAAKLLEDRVFDSVIEDRYSSFKSGIGADFENDKVTFKELEDYVIDKPQSE
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHCCCCHHH
LIAATKSGHLEQLKSTLNNYIFTVLGK
HHHHHCCCHHHHHHHHHHHEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA