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The map label for this gene is ald1 [H]

Identifier: 116491980

GI number: 116491980

Start: 197497

End: 198603

Strand: Direct

Name: ald1 [H]

Synonym: PEPE_0166

Alternate gene names: 116491980

Gene position: 197497-198603 (Clockwise)

Preceding gene: 116491979

Following gene: 116491981

Centisome position: 10.78

GC content: 41.19

Gene sequence:

>1107_bases
ATGAAAATTGCTGTAATTAAGGAGCAAAAAGAAGGCGAAGGACGGGTAGCAGCCACACCTGAAAATGTGCAAAAGATGGT
AGAAGCTGGAAATGAAGTTCTTGTGGAGCGCGATGCAGGAATTGGTGCCGGATTTTCCAATGAAGAATTTGAAAATGCAG
GAGGAAAAATTGTTTCTCATGCGGAAGCTTGGAAGGCTAAGTTGTGTATTAAAGTTAAGGAGCCTGACGAAGAAGAATAT
CAATATTTTGAAAAGGGTAAGATTGTTTGGGGCTTCCAGCATTTAGCCTCTGCAAAAGCTACCGTGGAAGCTATGATGCA
AGCAGGAGTAACGGCAATTGGTGGTGAAACGATTGTCAAAGATGGAAAACTAGAACTGTTAGCACCAATGAGCCAAATTG
CAGGGCGCCGCTCAGTAATCATGGGAGCATATTATTTAGAAGCGCAACATCAAGGCGCTGGTATTTTATTGTCAGGAATT
CCAGGCATGATTTCAGCGGGTAATGTTGTAATTTTTGGTGGCGGTAACGCTGCTACCGGTGCAGCAGATACAGCACTGGG
ATTAGGTTGCTCAGTGGTAATTATTGAATTGAACGACCAGAGAATTCAACAGCTCCAAAAATTATATAAAGGTAAAAAAG
TTCGAGTCGTTAAGTCAAATGAAGCAAATTTAGCCCAAGAAATCAAAGATGCTGATTTATTTATATCGACCATTTTAATT
CCAGGTTCTCGGCCACCCAAGTTGGTTAAAGAATCGATGGTCAAAAAGATGAAGAAGGGCTCAGTCATCGTTGATATTGC
AATTGATCAAGGCGGAACGGTAGAAACCATTGACCATCCAACGACGATTGACGATCCAATTTTTATTAAAGATGGTGTAA
TTCACTATGCTGTACCTAATCAACCAGGAGCAGTTCCACGGACATCCACGATGGCTTTGGCTGCCGGTAATTTAGATTAT
CTATTGGAAATAGCCGATCAGGGGATTGAAGCTGCTGGTAAAAATGATCCAGCATTAGCATCTGGGATTAACCTGTATGA
AGGAAAAATTACTAATCAAGGTTTGGCAGACTCCTTGAATCTTCCATATACTGAACTGAAACTATAA

Upstream 100 bases:

>100_bases
TTAAAGAAACAAATGTTTTTTTAAGGGAGATACCTTTTATTTTGGTTAACTTTGTGCAATACTACACATGTAAATAATTA
AATTCTAAGGAAGTGTCTTT

Downstream 100 bases:

>100_bases
AAAGGGGGTGGCGTTGATGTTAGTAGAGAAAGAACCCAGAAACCAAGTTGTAGCAGCAACCGATAATTTATTAAATCTAA
ACCAGATTGAAGAAGCCCGC

Product: L-alanine dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 368; Mature: 368

Protein sequence:

>368_residues
MKIAVIKEQKEGEGRVAATPENVQKMVEAGNEVLVERDAGIGAGFSNEEFENAGGKIVSHAEAWKAKLCIKVKEPDEEEY
QYFEKGKIVWGFQHLASAKATVEAMMQAGVTAIGGETIVKDGKLELLAPMSQIAGRRSVIMGAYYLEAQHQGAGILLSGI
PGMISAGNVVIFGGGNAATGAADTALGLGCSVVIIELNDQRIQQLQKLYKGKKVRVVKSNEANLAQEIKDADLFISTILI
PGSRPPKLVKESMVKKMKKGSVIVDIAIDQGGTVETIDHPTTIDDPIFIKDGVIHYAVPNQPGAVPRTSTMALAAGNLDY
LLEIADQGIEAAGKNDPALASGINLYEGKITNQGLADSLNLPYTELKL

Sequences:

>Translated_368_residues
MKIAVIKEQKEGEGRVAATPENVQKMVEAGNEVLVERDAGIGAGFSNEEFENAGGKIVSHAEAWKAKLCIKVKEPDEEEY
QYFEKGKIVWGFQHLASAKATVEAMMQAGVTAIGGETIVKDGKLELLAPMSQIAGRRSVIMGAYYLEAQHQGAGILLSGI
PGMISAGNVVIFGGGNAATGAADTALGLGCSVVIIELNDQRIQQLQKLYKGKKVRVVKSNEANLAQEIKDADLFISTILI
PGSRPPKLVKESMVKKMKKGSVIVDIAIDQGGTVETIDHPTTIDDPIFIKDGVIHYAVPNQPGAVPRTSTMALAAGNLDY
LLEIADQGIEAAGKNDPALASGINLYEGKITNQGLADSLNLPYTELKL
>Mature_368_residues
MKIAVIKEQKEGEGRVAATPENVQKMVEAGNEVLVERDAGIGAGFSNEEFENAGGKIVSHAEAWKAKLCIKVKEPDEEEY
QYFEKGKIVWGFQHLASAKATVEAMMQAGVTAIGGETIVKDGKLELLAPMSQIAGRRSVIMGAYYLEAQHQGAGILLSGI
PGMISAGNVVIFGGGNAATGAADTALGLGCSVVIIELNDQRIQQLQKLYKGKKVRVVKSNEANLAQEIKDADLFISTILI
PGSRPPKLVKESMVKKMKKGSVIVDIAIDQGGTVETIDHPTTIDDPIFIKDGVIHYAVPNQPGAVPRTSTMALAAGNLDY
LLEIADQGIEAAGKNDPALASGINLYEGKITNQGLADSLNLPYTELKL

Specific function: May play a role in cell wall synthesis as L-alanine is an important constituent of the peptidoglycan layer [H]

COG id: COG0686

COG function: function code E; Alanine dehydrogenase

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AlaDH/PNT family [H]

Homologues:

Organism=Homo sapiens, GI122939155, Length=356, Percent_Identity=26.4044943820225, Blast_Score=103, Evalue=3e-22,
Organism=Homo sapiens, GI122939153, Length=356, Percent_Identity=26.4044943820225, Blast_Score=103, Evalue=3e-22,
Organism=Escherichia coli, GI1787887, Length=349, Percent_Identity=28.080229226361, Blast_Score=119, Evalue=3e-28,
Organism=Caenorhabditis elegans, GI17550456, Length=351, Percent_Identity=27.9202279202279, Blast_Score=137, Evalue=7e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007698
- InterPro:   IPR008142
- InterPro:   IPR008143
- InterPro:   IPR007886
- InterPro:   IPR008141 [H]

Pfam domain/function: PF01262 AlaDh_PNT_C; PF05222 AlaDh_PNT_N [H]

EC number: =1.4.1.1 [H]

Molecular weight: Translated: 39107; Mature: 39107

Theoretical pI: Translated: 5.16; Mature: 5.16

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIAVIKEQKEGEGRVAATPENVQKMVEAGNEVLVERDAGIGAGFSNEEFENAGGKIVSH
CEEEEEECCCCCCCCEEECHHHHHHHHHCCCEEEEEECCCCCCCCCCCHHHCCCCCEEEH
AEAWKAKLCIKVKEPDEEEYQYFEKGKIVWGFQHLASAKATVEAMMQAGVTAIGGETIVK
HHHCCEEEEEEECCCCHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHHCCCEEECCCEEEE
DGKLELLAPMSQIAGRRSVIMGAYYLEAQHQGAGILLSGIPGMISAGNVVIFGGGNAATG
CCCEEEECCHHHHCCCCEEEEEEEEEEECCCCCEEEEECCCCCEECCCEEEECCCCCCCC
AADTALGLGCSVVIIELNDQRIQQLQKLYKGKKVRVVKSNEANLAQEIKDADLFISTILI
CCHHHHCCCEEEEEEEECHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHEEEEEEEE
PGSRPPKLVKESMVKKMKKGSVIVDIAIDQGGTVETIDHPTTIDDPIFIKDGVIHYAVPN
CCCCCHHHHHHHHHHHHHCCCEEEEEEECCCCEEEECCCCCCCCCCEEEECCEEEEECCC
QPGAVPRTSTMALAAGNLDYLLEIADQGIEAAGKNDPALASGINLYEGKITNQGLADSLN
CCCCCCCCCEEEEEECCHHHHHHHHHCCHHHCCCCCCCHHCCCEEEECCCCCCCCCCCCC
LPYTELKL
CCHHHHCC
>Mature Secondary Structure
MKIAVIKEQKEGEGRVAATPENVQKMVEAGNEVLVERDAGIGAGFSNEEFENAGGKIVSH
CEEEEEECCCCCCCCEEECHHHHHHHHHCCCEEEEEECCCCCCCCCCCHHHCCCCCEEEH
AEAWKAKLCIKVKEPDEEEYQYFEKGKIVWGFQHLASAKATVEAMMQAGVTAIGGETIVK
HHHCCEEEEEEECCCCHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHHCCCEEECCCEEEE
DGKLELLAPMSQIAGRRSVIMGAYYLEAQHQGAGILLSGIPGMISAGNVVIFGGGNAATG
CCCEEEECCHHHHCCCCEEEEEEEEEEECCCCCEEEEECCCCCEECCCEEEECCCCCCCC
AADTALGLGCSVVIIELNDQRIQQLQKLYKGKKVRVVKSNEANLAQEIKDADLFISTILI
CCHHHHCCCEEEEEEEECHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHEEEEEEEE
PGSRPPKLVKESMVKKMKKGSVIVDIAIDQGGTVETIDHPTTIDDPIFIKDGVIHYAVPN
CCCCCHHHHHHHHHHHHHCCCEEEEEEECCCCEEEECCCCCCCCCCEEEECCEEEEECCC
QPGAVPRTSTMALAAGNLDYLLEIADQGIEAAGKNDPALASGINLYEGKITNQGLADSLN
CCCCCCCCCEEEEEECCHHHHHHHHHCCHHHCCCCCCCHHCCCEEEECCCCCCCCCCCCC
LPYTELKL
CCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA