Click here to switch to the map view.

The map label for this gene is argK [C]

Identifier: 116332503

GI number: 116332503

Start: 65026

End: 65976

Strand: Reverse

Name: argK [C]

Synonym: LBJ_4061

Alternate gene names: 116332503

Gene position: 65976-65026 (Counterclockwise)

Preceding gene: 116332504

Following gene: 116332500

Centisome position: 22.01

GC content: 45.43

Gene sequence:

>951_bases
GTGAAACATCGCAAAGAAGATCTCGCGAAACTCATCGAAGGAGCACGCGAAGGGGAAAAATTTCCCCTCGCGAAGCTCAT
CTCCGGCGTCGAAAAACCGGATTCCTTCGAGTTTAGAAAGAACCTCTTTGAATCCCTTGCTTCCCAAGGCCTCTCAGGTC
AAAATTCTCTTACCGTGGGTTTTACCGGAACTCCCGGAGCCGGAAAATCCTCCTTACTCGGCAAACTCGCGACTCAATTT
TTAAAAGCCGATAACGGAGAAACGATGGCGATCGTCGCAATCGATCCCTCCAGCCATATCTCCGGCGGTTCTTTACTCGG
CGATAGAACCCGTCTTTTTCTTCCGGCAAGAGAGAAAAGGATTTACTTCCGTTCCCAACCGAGTCAATTAGAACTAGGCG
GAGTCAATCCGTACACGTACCACGTAATTCGATTGCTTCGTCGTTTTTTTCGTTACGTGTTTATCGAAACCGTCGGAATC
GGCCAGAATGAAATCGAAGTCTTCAAACTTACGGACCTTTCCTTTCTCGTTTTACAACCGTTAGGCGGAGATCAGGTTCA
GTTTATGAAAAGCGGAATCATGGAAGTTCCGGATTCCTTCATTATCAACAAATGCGACGAAGAAGTTCTTGCGAATTCCA
GTTATCATATGTTAACCACTACCCTGGAATTTCTAAAAGACGTTATGCCGGGAAAAAATCTTCCCCCCGTTTTTAAAACC
TCCGCGAAAACCAAGTATGGAATCGACGATCTTCTGGAATTTATCCGTAAGGCAAAACCCACCGTCGATCGTTCCAAAGA
AACGGATCTTCAGCTTAAGAAATGGATCAAGAACGAGTTCGGAAATTTCGGCCTGAAGATCATCGAACATCTCCCCTACT
CCGATCCTTCGAGTTTTGAAACCTTAGAAGACAGAGCGCTTCAGGAAATTCGAAAAAATCTGAATTCTTAA

Upstream 100 bases:

>100_bases
TCACTCCAAAAGACTACGATCTAATGGACGTGATGGAAAGAATCATCGATATCATTTCTCAGACGATAAAAGCCGCATAA
CGCGGTTTGACGGGTATGCC

Downstream 100 bases:

>100_bases
TTGATCCCTTCATTCATACTTTTAGGTAAGTTCGACGGTTGAAAGTTTGGGCGAATCCAGCCTTTGACAAGCAAAGGCTG
GACCGCGCTTTTCGTTCCAA

Product: protein kinase involved in LAO amino acid transport and metabolism

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 316; Mature: 316

Protein sequence:

>316_residues
MKHRKEDLAKLIEGAREGEKFPLAKLISGVEKPDSFEFRKNLFESLASQGLSGQNSLTVGFTGTPGAGKSSLLGKLATQF
LKADNGETMAIVAIDPSSHISGGSLLGDRTRLFLPAREKRIYFRSQPSQLELGGVNPYTYHVIRLLRRFFRYVFIETVGI
GQNEIEVFKLTDLSFLVLQPLGGDQVQFMKSGIMEVPDSFIINKCDEEVLANSSYHMLTTTLEFLKDVMPGKNLPPVFKT
SAKTKYGIDDLLEFIRKAKPTVDRSKETDLQLKKWIKNEFGNFGLKIIEHLPYSDPSSFETLEDRALQEIRKNLNS

Sequences:

>Translated_316_residues
MKHRKEDLAKLIEGAREGEKFPLAKLISGVEKPDSFEFRKNLFESLASQGLSGQNSLTVGFTGTPGAGKSSLLGKLATQF
LKADNGETMAIVAIDPSSHISGGSLLGDRTRLFLPAREKRIYFRSQPSQLELGGVNPYTYHVIRLLRRFFRYVFIETVGI
GQNEIEVFKLTDLSFLVLQPLGGDQVQFMKSGIMEVPDSFIINKCDEEVLANSSYHMLTTTLEFLKDVMPGKNLPPVFKT
SAKTKYGIDDLLEFIRKAKPTVDRSKETDLQLKKWIKNEFGNFGLKIIEHLPYSDPSSFETLEDRALQEIRKNLNS
>Mature_316_residues
MKHRKEDLAKLIEGAREGEKFPLAKLISGVEKPDSFEFRKNLFESLASQGLSGQNSLTVGFTGTPGAGKSSLLGKLATQF
LKADNGETMAIVAIDPSSHISGGSLLGDRTRLFLPAREKRIYFRSQPSQLELGGVNPYTYHVIRLLRRFFRYVFIETVGI
GQNEIEVFKLTDLSFLVLQPLGGDQVQFMKSGIMEVPDSFIINKCDEEVLANSSYHMLTTTLEFLKDVMPGKNLPPVFKT
SAKTKYGIDDLLEFIRKAKPTVDRSKETDLQLKKWIKNEFGNFGLKIIEHLPYSDPSSFETLEDRALQEIRKNLNS

Specific function: May have GTPase activity. May also bind and hydrolyze ATP. May function as chaperone [H]

COG id: COG1703

COG function: function code E; Putative periplasmic protein kinase ArgK and related GTPases of G3E family

Gene ontology:

Cell location: Inner Membrane-Associated [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ArgK family [H]

Homologues:

Organism=Homo sapiens, GI26892295, Length=290, Percent_Identity=31.7241379310345, Blast_Score=119, Evalue=3e-27,
Organism=Escherichia coli, GI1789285, Length=257, Percent_Identity=36.1867704280156, Blast_Score=133, Evalue=1e-32,
Organism=Caenorhabditis elegans, GI71994275, Length=252, Percent_Identity=31.7460317460317, Blast_Score=123, Evalue=1e-28,
Organism=Caenorhabditis elegans, GI71994271, Length=252, Percent_Identity=31.7460317460317, Blast_Score=123, Evalue=1e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005129
- InterPro:   IPR003593 [H]

Pfam domain/function: PF03308 ArgK [H]

EC number: 2.7.-.- [C]

Molecular weight: Translated: 35516; Mature: 35516

Theoretical pI: Translated: 9.18; Mature: 9.18

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKHRKEDLAKLIEGAREGEKFPLAKLISGVEKPDSFEFRKNLFESLASQGLSGQNSLTVG
CCCCHHHHHHHHHHHHCCCCCCHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCCCCCEEEE
FTGTPGAGKSSLLGKLATQFLKADNGETMAIVAIDPSSHISGGSLLGDRTRLFLPAREKR
ECCCCCCCHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCCEECCCCEEEECCHHCE
IYFRSQPSQLELGGVNPYTYHVIRLLRRFFRYVFIETVGIGQNEIEVFKLTDLSFLVLQP
EEEECCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCEEEEEEC
LGGDQVQFMKSGIMEVPDSFIINKCDEEVLANSSYHMLTTTLEFLKDVMPGKNLPPVFKT
CCCHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCCCCC
SAKTKYGIDDLLEFIRKAKPTVDRSKETDLQLKKWIKNEFGNFGLKIIEHLPYSDPSSFE
CCCCCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCHHH
TLEDRALQEIRKNLNS
HHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKHRKEDLAKLIEGAREGEKFPLAKLISGVEKPDSFEFRKNLFESLASQGLSGQNSLTVG
CCCCHHHHHHHHHHHHCCCCCCHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCCCCCEEEE
FTGTPGAGKSSLLGKLATQFLKADNGETMAIVAIDPSSHISGGSLLGDRTRLFLPAREKR
ECCCCCCCHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCCEECCCCEEEECCHHCE
IYFRSQPSQLELGGVNPYTYHVIRLLRRFFRYVFIETVGIGQNEIEVFKLTDLSFLVLQP
EEEECCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCEEEEEEC
LGGDQVQFMKSGIMEVPDSFIINKCDEEVLANSSYHMLTTTLEFLKDVMPGKNLPPVFKT
CCCHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCCCCC
SAKTKYGIDDLLEFIRKAKPTVDRSKETDLQLKKWIKNEFGNFGLKIIEHLPYSDPSSFE
CCCCCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCHHH
TLEDRALQEIRKNLNS
HHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Arg [C]

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12622808 [H]